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Journal Articles

Macrophage metabolic adaptation to heme detoxification involves CO-dependent activation of the pentose phosphate pathway

Gael F. P. Bories, Scott Yeudall, Vlad Serbulea, Todd E. Fox, Brant E. Isakson, Norbert Leitinger

Blood (2020) 136 (13): 1535–1548.

https://doi.org/10.1182/blood.2020004964

Published: 2020

Includes: Supplemental data

Journal Articles

Predictors of Transfer to Different Facility at Discharge in Patients Admitted with Hematologic Malignancy: A Nationwide Inpatient Sample (NIS) Database Analysis

Sunny R K Singh, MD, Sindhu Malapati, MD, Rohit Kumar, MD, Olekdandra Lupak, MD, Philip Kuriakose, MD

Blood (2019) 134 (Supplement_1): 2132.

https://doi.org/10.1182/blood-2019-127604

Published: 2019

Journal Articles

Post-Translational Mechanisms of NT5C2 Activation As Non-Genetic Drivers of Chemotherapy Resistance in Relapsed Acute Lymphoblastic Leukemia

Clara Reglero, PhD, Dieck L. Chelsea, PhD, Jui Wan Loh, Hossein Khiabanian, PhD, Adolfo Ferrando, MD, PhD

Blood (2019) 134 (Supplement_1): 728.

https://doi.org/10.1182/blood-2019-128615

Published: 2019

Journal Articles

Dual Targeting of ALDH1 and ALDH3: A Promising Therapeutic Approach in Acute Myeloid Leukemia

Mileidys Perez-Alea, Sr., PhD, Julien Colle, Jr., MD, Muhube Yazir, Jr., MSc, Céline Baier, Jr., PhD, Yasmine Labiad, PhD, Isabelle Arnoux, Sr., Hematologist, Geoffroy Venton, Jr., PhD MD, Guillaume Guillaume, MSc, Ismail Ceylan, MSc, Regis T. Costello, Sr., MD PhD

Blood (2019) 134 (Supplement_1): 3364.

https://doi.org/10.1182/blood-2019-126484

Published: 2019

Journal Articles

Lentiviral Gene Therapy with Autologous Hematopoietic Stem and Progenitor Cells (HSPCs) for the Treatment of Severe Combined Immune Deficiency Due to Adenosine Deaminase Deficiency (ADA-SCID): Results in an Expanded Cohort

Blood (2019) 134 (Supplement_1): 3345.

https://doi.org/10.1182/blood-2019-123432

Published: 2019

Journal Articles

Paraoxonase 2 Enables Initiation of B-ALL By Subverting Metabolic Gatekeeper Functions

Lili Pan, MD, Chao Hong, PhD, Gang Xiao, PhD, Huimin Geng, PhD, Shaoyuan Wang, MD, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 746.

https://doi.org/10.1182/blood-2019-125171

Published: 2019

Journal Articles

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

Etienne De Braekeleer, PhD MSc, Joanne Hsu, BS, Celine Hervieu, MSc, Konstantinos Tzelepis, PhD, Stefano Indraccolo, MD, Alan J. Warren, PhD FRCP, FRCPath, Irmela Jeremias, MD PhD, David Fernandez Antoran, PhD, Phil H Jones, PhD, Margaret A. Goodell, PhD, George S. Vassiliou

Blood (2018) 132 (Supplement 1): 2615.

https://doi.org/10.1182/blood-2018-99-118827

Published: 2018

Journal Articles

Coordination of Pro- and Anti-Inflammatory Signals Determine Human Hematopoietic Stem and Progenitor Cell Expansion

Jalila Chagraoui, PhD, Elisa Tomellini, PhD, Leo Aubert, Iman Fares, PhD, Jean-Francois Spinella, PhD, Simon Girard, Nadine Mayotte, Philippe P Roux, PhD, Guy Sauvageau, MD, PhD

Blood (2018) 132 (Supplement 1): 2555.

https://doi.org/10.1182/blood-2018-99-111917

Published: 2018

Journal Articles

Toward a Proteome-Complete Computational Model of the Human Red Blood Cell

James T Yurkovich, PhD, Laurence Yang, PhD, Bernhard O Palsson, PhD

Blood (2018) 132 (Supplement 1): 4888.

https://doi.org/10.1182/blood-2018-99-114969

Published: 2018

Journal Articles

Defective Autophagy Process and Increased ROS Formation in Primary Myelofibrosis

Guanfang Shi, PhD, Sreenath Kodali, MBBS, MD, Ching Wong, MD, Vladimir K. Gotlieb, MD, Jen-Chin Wang, MD

Blood (2018) 132 (Supplement 1): 3069.

https://doi.org/10.1182/blood-2018-99-112406

Published: 2018

Journal Articles

Adhesion of Sickle RBCs to Heme-Activated Endothelial Cells Correlates with Patient Clinical Phenotypes

Erdem Kucukal, MS, Anton Ilich, MD, Nigel S. Key, MBChB, FRCP, Jane A. Little, MD, Umut A. Gurkan, PhD

Blood (2017) 130 (Supplement 1): 959.

https://doi.org/10.1182/blood.V130.Suppl_1.959.959

Published: 2017

Journal Articles

The High NRF2 Expression Confers Chemotherapy Resistance through Upregulated DUSP1 in Myelodysplastic Syndromes

Peipei Lin, Yanling Ren, Xinping Zhou, Chen Mei, Chao Hu, Yingwan Luo, Yile Zhou, Xiaomei Yan, Gang Huang, PhD, Hongyan Tong, PhD

Blood (2017) 130 (Supplement 1): 2956.

https://doi.org/10.1182/blood.V130.Suppl_1.2956.2956

Published: 2017

Journal Articles

Delayed Expansion of Murine BCR-ABL1 + Leukemia By Genetic and Pharmacological Inhibition of NOX2

Hanna Grauers Wiktorin, Msc, Malin Nilsson, Msc, Tina Nilsson, Msc, Johan Gustafsson, Msc, Ebru Aydin, Msc, Anders Ståhlberg, PhD, Fredrik B Thoren, Kristoffer Hellstrand, MD PhD, Lars Palmqvist, Professor, Anna Martner, PhD

Blood (2017) 130 (Supplement 1): 2879.

https://doi.org/10.1182/blood.V130.Suppl_1.2879.2879

Published: 2017

Journal Articles

Endogenous Retrovirus Derepression Drives Ectopic UGT2B17 Overexpression in Multiple Myeloma Cells: Molecular Sequelae and Pathophysiological Implications

Spyros Ioannis Papamichos, MD PhD, Eleftheria Lamprianidou, Chryssoula Kordella, Emmanouil Spanoudakis, Menelaos Konstantinos Papoutselis, Ioannis Kotsianidis, PhD

Blood (2017) 130 (Supplement 1): 4978.

https://doi.org/10.1182/blood.V130.Suppl_1.4978.4978

Published: 2017

Journal Articles

Genome-Wide CRISPR/Cas9-Mediated Loss-of-Function Screening in Human Erythroleukemic Cells Identifies Novel Cellular Components Involved in Iron and Heme Trafficking

Amin Sobh, Alex Loguinov, PhD, Paula Fraenkel, MD, Chris D Vulpe, MD PhD

Blood (2017) 130 (Supplement 1): 169.

https://doi.org/10.1182/blood.V130.Suppl_1.169.169

Published: 2017

Journal Articles

MMSET I Acts As an Oncoprotein and Regulates GLO1 Expression in T(4;14) Multiple Myeloma Cells

Zhigang Xie, PhD, Jing Yuan Chooi, BSc, Sabrina Hui Min Toh, Bachelor, Wee Joo Chng, MB ChB, MRCP, PhD

Blood (2017) 130 (Supplement 1): 563.

https://doi.org/10.1182/blood.V130.Suppl_1.563.563

Published: 2017

Journal Articles

PON2 Exemplifies a Unique Dependency of B Cell Lineage ALL Cells on Detoxifying Lactonases

Gang Xiao, PhD, Chao Hong, PhD, Huimin Geng, PhD, Markus Muschen, MD

Blood (2017) 130 (Supplement 1): 882.

https://doi.org/10.1182/blood.V130.Suppl_1.882.882

Published: 2017

Journal Articles

The Impact of Antimicrobial Prophylaxis during Induction Chemotherapy for Acute Myeloid Leukemia in the Current Era

Marla M. Jalbut, MD, Evan C. Chen, MD, Gabriela S. Hobbs, MD, Ashley M. Perry, BS, Lillian Werner, MS, Philip C. Amrein, MD, Amir T. Fathi, MD MD BS, Andrew M. Brunner, MD

Blood (2017) 130 (Supplement 1): 2586.

https://doi.org/10.1182/blood.V130.Suppl_1.2586.2586

Published: 2017

Journal Articles

Allogeneic Umbilical Cord Blood Infusion for Adults with Ischemic Stroke (CoBIS): Clinical Outcomes from a Phase 1 Safety Study

Joanne Kurtzberg, MD, Jesse D Troy, PhD, Ellen Bennett, PhD, Samir Belagaje, MD, Elizabeth J. Shpall, MD, Jonathan Wiese, MSN, RN, CNL, John Volpi, MD, Daniel Laskowitz, MD

Blood (2016) 128 (22): 2284.

https://doi.org/10.1182/blood.V128.22.2284.2284

Published: 2016

Journal Articles

Persisting Hyperbilirubinemia in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Chronically Treated with Eculizumab: The Role of Hepatocanalicular Transport Variants

Ferras Alashkar, MD, Ali Canbay, MD, Dörte Herich-Terhürne, Ulrich Dührsen, MD, Frank Lammert, MD, Alexander Röth, MD

Blood (2015) 126 (23): 940.

https://doi.org/10.1182/blood.V126.23.940.940

Published: 2015

NARROW

Macrophage metabolic adaptation to heme detoxification involves CO-dependent activation of the pentose phosphate pathway

Predictors of Transfer to Different Facility at Discharge in Patients Admitted with Hematologic Malignancy: A Nationwide Inpatient Sample (NIS) Database Analysis

Post-Translational Mechanisms of NT5C2 Activation As Non-Genetic Drivers of Chemotherapy Resistance in Relapsed Acute Lymphoblastic Leukemia

Dual Targeting of ALDH1 and ALDH3: A Promising Therapeutic Approach in Acute Myeloid Leukemia

Lentiviral Gene Therapy with Autologous Hematopoietic Stem and Progenitor Cells (HSPCs) for the Treatment of Severe Combined Immune Deficiency Due to Adenosine Deaminase Deficiency (ADA-SCID): Results in an Expanded Cohort

Paraoxonase 2 Enables Initiation of B-ALL By Subverting Metabolic Gatekeeper Functions

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

Coordination of Pro- and Anti-Inflammatory Signals Determine Human Hematopoietic Stem and Progenitor Cell Expansion

Toward a Proteome-Complete Computational Model of the Human Red Blood Cell

Defective Autophagy Process and Increased ROS Formation in Primary Myelofibrosis

Adhesion of Sickle RBCs to Heme-Activated Endothelial Cells Correlates with Patient Clinical Phenotypes

The High NRF2 Expression Confers Chemotherapy Resistance through Upregulated DUSP1 in Myelodysplastic Syndromes

Delayed Expansion of Murine BCR-ABL1 + Leukemia By Genetic and Pharmacological Inhibition of NOX2

Endogenous Retrovirus Derepression Drives Ectopic UGT2B17 Overexpression in Multiple Myeloma Cells: Molecular Sequelae and Pathophysiological Implications

Genome-Wide CRISPR/Cas9-Mediated Loss-of-Function Screening in Human Erythroleukemic Cells Identifies Novel Cellular Components Involved in Iron and Heme Trafficking

MMSET I Acts As an Oncoprotein and Regulates GLO1 Expression in T(4;14) Multiple Myeloma Cells

PON2 Exemplifies a Unique Dependency of B Cell Lineage ALL Cells on Detoxifying Lactonases

The Impact of Antimicrobial Prophylaxis during Induction Chemotherapy for Acute Myeloid Leukemia in the Current Era

Allogeneic Umbilical Cord Blood Infusion for Adults with Ischemic Stroke (CoBIS): Clinical Outcomes from a Phase 1 Safety Study

Persisting Hyperbilirubinemia in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Chronically Treated with Eculizumab: The Role of Hepatocanalicular Transport Variants

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American Society of Hematology

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American Society of Hematology

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