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Journal Articles

The metabolic enzyme pyruvate kinase M2 regulates platelet function and arterial thrombosis

Manasa K. Nayak, Madankumar Ghatge, Gagan D. Flora, Nirav Dhanesha, Manish Jain, Kathleen R. Markan, Matthew J. Potthoff, Steven R. Lentz, Anil K. Chauhan
Journal: Blood
Blood (2021) 137 (12): 1658–1668.
https://doi.org/10.1182/blood.2020007140
Published: 2021
Includes: Supplemental data
Journal Articles

Activated but Not Quiescent Hematopoietic Stem Cells Rely Readily on Glycolysis As Their Main Source of Energy

Tasleem Arif, PhD, Raymond Liang, PhD, Maio Lin, Msc, Svetlana Kalmikova, Msc, Artem Kasianov, PhD, Vijay Menon, PhD, Dmitri Papatsenko, PhD, Saghi Ghaffari, PhD MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 271.
https://doi.org/10.1182/blood-2019-129099
Published: 2019
Journal Articles

Chronic lymphocytic leukemia cells impair mitochondrial fitness in CD8 + T cells and impede CAR T-cell efficacy

Jaco A. C. van Bruggen, Anne W. J. Martens, Joseph A. Fraietta, Tom Hofland, Sanne H. Tonino, Eric Eldering, Mark-David Levin, Peter J. Siska, Sanne Endstra, Jeffrey C. Rathmell, Carl H. June, David L. Porter, J. Joseph Melenhorst, Arnon P. Kater, Gerritje J. W. van der Windt
Journal: Blood
Blood (2019) 134 (1): 44–58.
https://doi.org/10.1182/blood.2018885863
Published: 2019
Includes: Supplemental data
Journal Articles

Metabolic Reprogramming of Dendritic Cells Is Controlled By the Mir-142

Yaping Sun, MD PhD MS, Thomas Saunders, PhD, Katherine Oravecz-Wilson, BS, MS, Sydney Bridges, BS, Richard McEachin, PhD, Julia Wu, PhD, Stephanie Kim, Cynthia Zajac, Tomomi Toubai, MDPhD, Hideaki Fujiwara, Israel Henig, MD, Dan Peltier, MD, Pavan Reddy, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2265.
https://doi.org/10.1182/blood.V130.Suppl_1.2265.2265
Published: 2017
Journal Articles

Control of Hematopoietic Stem Cell Function through Epigenetic Regulation of Energy Metabolism and Genome Integrity

Zhenhua Yang, PhD, Hao Jiang
Journal: Blood
Blood (2017) 130 (Supplement 1): 772.
https://doi.org/10.1182/blood.V130.Suppl_1.772.772
Published: 2017
Journal Articles

Effects of Isoprenoid Biosynthetic Pathway Inhibition on Glucose Uptake in Myeloma Cells

Kaitlyn M. Dykstra, PhD, Sarah A. Holstein, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3300.
https://doi.org/10.1182/blood.V128.22.3300.3300
Published: 2016
Journal Articles

Glucose Transporter 3 in Platelets Facilitates Alpha-Granule Mediated Glucose Uptake, Driving Intragranular Glycolysis That Is Required for Platelet Degranulation and Activation

Fidler P.L Trevor, Elizabeth Middleton, MD, Jesse W Rowley, PhD, Luc Boudreau, PhD, Robert A. Campbell, PhD, Rhonda Souvenir, PhD, Eric Boilard, PhD, E. Dale Abel, MD PhD, Andrew S. Weyrich, PhD
Journal: Blood
Blood (2015) 126 (23): 417.
https://doi.org/10.1182/blood.V126.23.417.417
Published: 2015
Journal Articles

Distinct Bone Marrow Blood Vessels Differentially Regulate Normal and Malignant Hematopoietic Stem and Progenitor Cells

Tomer Itkin, PhD, Shiri Gur Cohen, PhD, Joel A. Spencer, PhD, Amir Schajnovitz, Saravana K. Ramasamy, PhD, Anjali P. Kusumbe, PhD, Yookyung Jung, PhD, Guy Ledergor, MD, Idan Milo, PhD, Michael Gustave Poulos, PhD, Maria Garcia Fernandez, PhD, Alexander Kalinkovich, MDPhD, Aya Ludin, Orit Kollet, PhD, Guy Shakhar, PhD, Simon Mendez-Ferrer, PhD, Jason M. Butler, PhD, Shahin Rafii, MD, Ralf H. Adams, PhD, David T. Scadden, MD, Charles P. Lin, Tsvee Lapidot, PhD
Journal: Blood
Blood (2015) 126 (23): 664.
https://doi.org/10.1182/blood.V126.23.664.664
Published: 2015
Journal Articles

Cereblon Deficiency Leads to Alteration in c-Myc Regulated Genes, Increased Glucose Uptake and Resistance to JQ1 Bromodomain Inhibition

Matthew S Beatty, PhD, Rebecca S Hesterberg, BA, Ying Han, MD, Eric Padron, MD, Adam W Mailloux, PhD, Sean Yoder, M.S, Anjali M Rajadhyaksha, PhD, Alan F. List, MD, Pearlie K Epling-Burnette, PhD
Journal: Blood
Blood (2015) 126 (23): 286.
https://doi.org/10.1182/blood.V126.23.286.286
Published: 2015
Journal Articles

Stromal cell–mediated glycolytic switch in CLL cells involves Notch-c-Myc signaling

Brief Report
Regina Jitschin, Martina Braun, Mirjeta Qorraj, Domenica Saul, Katarina Le Blanc, Thorsten Zenz, Dimitrios Mougiakakos
Journal: Blood
Blood (2015) 125 (22): 3432–3436.
https://doi.org/10.1182/blood-2014-10-607036
Published: 2015
Includes: Supplemental data
Journal Articles

Differential Dependence On Aerobic Glycolysis In Normal and Malignant Hematopoietic Stem and Progenitor Cells To Sustain Daughter Cell Production

Ying-Hua Wang, PhD, William J. Israelsen, Dongjun Lee, PhD, Vionnie W.C. Yu, PhD, Nathaniel T. Jeanson, PhD, Clary B. Clish, PhD, Lewis C. Cantley, PhD, Matthew G. Vander Heiden, MD/PhD, David T. Scadden, MD
Journal: Blood
Blood (2013) 122 (21): 793.
https://doi.org/10.1182/blood.V122.21.793.793
Published: 2013
Journal Articles

Cited2 Is Required For The Maintenance Of Glycolytic Metabolism In Adult Hematopoietic Stem Cells

Jinwei Du, PhD, Qiang Li, PhD, Fangqiang Tang, PhD, Michelle Puchowitz, PhD, Hasashi Fujioka, PhD, Sally Dunwoodie, PhD, David Danielpour, PhD, Yu-Chung Yang, PhD
Journal: Blood
Blood (2013) 122 (21): 794.
https://doi.org/10.1182/blood.V122.21.794.794
Published: 2013
Journal Articles

Identification of HIF2α as an important STAT5 target gene in human hematopoietic stem cells

Szabolcs Fatrai, Albertus T. J. Wierenga, Simon M. G. J. Daenen, Edo Vellenga, Jan Jacob Schuringa
Journal: Blood
Blood (2011) 117 (12): 3320–3330.
https://doi.org/10.1182/blood-2010-08-303669
Published: 2011
Includes: Supplemental data
Journal Articles

IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival

Jessica A. Wofford, Heather L. Wieman, Sarah R. Jacobs, Yuxing Zhao, Jeffrey C. Rathmell
Journal: Blood
Blood (2008) 111 (4): 2101–2111.
https://doi.org/10.1182/blood-2007-06-096297
Published: 2008
Journal Articles

Abnormalities in Glucose Uptake and Metabolism in Imatinib-Resistant Bcr-Abl Positive Cells.

Natalie J. Serkova, PhD, Douglas J. Kominsky, Ph.D., Jaimi L. Brown, B.S., Jelena Miljus, M.S., Laszlo G. Boros, M.D., Gail S. Eckhardt, M.D., Junia V. Melo, M.D., Ph.D.
Journal: Blood
Blood (2006) 108 (11): 2338.
https://doi.org/10.1182/blood.V108.11.2338.2338
Published: 2006
Journal Articles

Antigen receptor–mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth

Cheryl A. Doughty, Blair F. Bleiman, Dean J. Wagner, Fay J. Dufort, Jennifer M. Mataraza, Mary F. Roberts, Thomas C. Chiles
Journal: Blood
Blood (2006) 107 (11): 4458–4465.
https://doi.org/10.1182/blood-2005-12-4788
Published: 2006
Journal Articles

Relationship between m-TOR-Mediated Upregulation of Glycolysis, Chemoresistance, and Prognosis in Patients with ALL.

Daniela Buglio, PhD, Marina Konopleva, MD, PhD, Teresa McQueen, BS, Ismael Samudio, PhD, Kristine R. Broglio, MS, BS, Vivian Ruvolo, Rooha Contractor, Wenjing Chen, MS, Hagop Kantarjian, MD, Michael Andreeff, MD, PhD, Mary A. Weiser, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 12.
https://doi.org/10.1182/blood.V106.11.12.12
Published: 2005