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Journal Articles

Paraoxonase 2 Enables Initiation of B-ALL By Subverting Metabolic Gatekeeper Functions

Lili Pan, MD, Chao Hong, PhD, Gang Xiao, PhD, Huimin Geng, PhD, Shaoyuan Wang, MD, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 746.

https://doi.org/10.1182/blood-2019-125171

Published: 2019

Journal Articles

IGF1R-IRS1/2 Signaling Pathway Is a Potential Target for FLT3-Mutated Acute Myeloid Leukemia

Juan L Coelho-Silva, BSc, MSc, Diego A Pereira-Martins, MSc, Virginia Campos Silvestrini, BSc, MSc, Eduardo M Rego, MD PhD, Vitor Marcel Faca, PhD, João Agostinho Machado-Neto, PhD, Fabiola Traina, MD PhD

Blood (2019) 134 (Supplement_1): 2689.

https://doi.org/10.1182/blood-2019-132129

Published: 2019

Journal Articles

Phospho-Proteomic Profiling of T-Cell Acute Lymphoblastic Leukemia Identifies Specific Kinase Activation Signatures That Can Predict Response to Targeted Therapy

Valentina Cordo', MSc, Rico Hagelaar, Sander Piersma, Thang V Pham, Connie Jimenez, PhD, Jules P.P. Meijerink, PhD

Blood (2019) 134 (Supplement_1): 4649.

https://doi.org/10.1182/blood-2019-122898

Published: 2019

Journal Articles

Glycemic Control in Patients Treated with Tyrosine Kinase Inhibitors for Chronic Myeloid Leukemia: A Systematic Review

Laura Spatafora, Breanne Golemiec, Lehana Thabane, PhD, Laura Banfield, Christopher M. Hillis, MD, Constantine Samaan, MD, Uma Athale, MD MBBS,MSc

Blood (2018) 132 (Supplement 1): 4273.

https://doi.org/10.1182/blood-2018-99-117464

Published: 2018

Journal Articles

High IGF1R Expression Is Associated with Worse Prognosis in CLL and Impacts Response to PI3K-δ Inhibitor Treatment

Annika Scheffold, Billy Michael Chelliah Jebaraj, PhD, Johannes Bloehdorn, MD, Eugen Tausch, MD, Jasmin Bahlo, PhD, Sandra Robrecht, PhD, Kirsten Fischer, MD, Michael Hallek, MD, Hartmut Döhner, MD, Daniel Mertens, PhD, Stephan Stilgenbauer, MD PhD

Blood (2017) 130 (Supplement 1): 390.

https://doi.org/10.1182/blood.V130.Suppl_1.390.390

Published: 2017

Journal Articles

Targeting Insulin-like Growth Factor/Insulin Receptor Signaling to Overcome JAK2 Inhibitor Persistence in Myeloproliferative Neoplasms

Lucia Mazzacurati, Que T. Lambert, Gary W. Reuther, PhD

Blood (2017) 130 (Supplement 1): 2935.

https://doi.org/10.1182/blood.V130.Suppl_1.2935.2935

Published: 2017

Journal Articles

CDC37 As a Novel Target for the Treatment of NPM1-ALK Expressing Anaplastic Large Cell Lymphomas

Sudhakiranmayi Kuravi, M.S., Elizabeth Parrott, M.A., Siddhartha Ganguly, MD, Anusha Vallurupalli, MD, Yogenthiran Saunthararajah, MD, Brian S Blagg, PhD, Jensen Roy, MD, Joseph P. McGuirk, DO, Ramesh Balusu, PhD

Blood (2017) 130 (Supplement 1): 2758.

https://doi.org/10.1182/blood.V130.Suppl_1.2758.2758

Published: 2017

Journal Articles

Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function

Blood (2017) 130 (12): 1445–1455.

https://doi.org/10.1182/blood-2017-02-767921

Published: 2017

Includes: Supplemental data

Journal Articles

Transcriptional Control of Glucose and Energy Supply Prevents Oncogenic Signaling and B Cell Transformation

Lai N Chan, PhD, Zhengshan Chen, MD PhD, Gang Xiao, PhD, Jaewoong Lee, PhD, Huimin Geng, PhD, Hurtz Christian, PhD, Valeria Cazzaniga, PhD, Giovanni Cazzaniga, PhD, Ross A Dickins, PhD, Markus Müschen, MD PhD

Blood (2016) 128 (22): 437.

https://doi.org/10.1182/blood.V128.22.437.437

Published: 2016

Journal Articles

Ponatinib Exerts Multiple Effects on Vascular Endothelial Cells: Possible Mechanisms and Explanations for the Adverse Vascular Events Seen in CML Patients Treated with Ponatinib

Emir Hadzijusufovic, DVM, Rudolf Kirchmair, MD, Markus Theurl, MD, Susanne Gamperl, MSc, Daniela Lener, Clemens Gutmann, Ursula Stanzl, Andrijana Kirsch, MD, Sasa Frank, PhD, Peter Valent, MD

Blood (2016) 128 (22): 1883.

https://doi.org/10.1182/blood.V128.22.1883.1883

Published: 2016

Journal Articles

A Genetic Risk Score for Insulin Resistance Identify Patients with Chronic Myeloid Leukemia, Treated with Nilotinib, Developing Diabetes

Bruno Martino, Claudia Labate, DSC, Caterina Alati, MD, Domenica Ielo, DSC, Carmelo Laganà, MD, Francesca Ronco, Corrado Mammì, MD

Blood (2016) 128 (22): 3098.

https://doi.org/10.1182/blood.V128.22.3098.3098

Published: 2016

Journal Articles

B-Lymphoid Transcription Factors Restrict Glycolytic Energy Supply for Oncogenic Signaling

Blood (2015) 126 (23): 1255.

https://doi.org/10.1182/blood.V126.23.1255.1255

Published: 2015

Journal Articles

Melphalan Affects Genes Critical for Myeloma Survival, Homing, and Response to Cytokines and Chemokines

Shmuel Yaccoby, Joshua Epstein, DSc, Pingping Qu, PhD, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Christoph Heuck, MD, Faith E Davies, MD, Alan Mitchell, Antje Hoering, PhD, John Crowley, PhD, Bart Barlogie, MD PhD, Gareth J Morgan, MDPhD

Blood (2015) 126 (23): 1808.

https://doi.org/10.1182/blood.V126.23.1808.1808

Published: 2015

Journal Articles

Ptdglc-Enriched Lipid Rafts Are a Novel Platform for Apoptosis Signaling in Human Neutrophilic Lineage Cells

Roudy Chiminch Ekyalongo, Noriko Yokoyama, Hitoshi Nakayama, Hideoki Ogawa, Yoko Tabe, Kenji Takamori, Yoshio Hirabayashi, Kazuhisa Iwabuchi

Blood (2015) 126 (23): 4968.

https://doi.org/10.1182/blood.V126.23.4968.4968

Published: 2015

Journal Articles

Metformin Therapy and Survival in Multiple Myeloma Among US Veterans with Diabetes Mellitus

Jesse Keller, MD, Kristen M. Sanfilippo, MD MPHS, Suhong Luo, MPH, Brian F. Gage, MDMSc, Kenneth R Carson, MD PhD

Blood (2015) 126 (23): 4502.

https://doi.org/10.1182/blood.V126.23.4502.4502

Published: 2015

Journal Articles

Growth Factor Receptor-Bound Protein 10 (Grb10) Regulates Hematopoietic Stem Cell (HSC) Self-Renewal Via Control of mTOR Signaling

Xiao Yan, Heather A Himburg, PhD, Phuong L Doan, MD, Mamle Quarmyne, PhD, Evelyn Tran, Liman Zhao, Nelson J. Chao, MD, John P Chute, MD

Blood (2015) 126 (23): 1160.

https://doi.org/10.1182/blood.V126.23.1160.1160

Published: 2015

Journal Articles

Preclinical Analysis of Linsitinib for the Treatment of Polycythemia Vera

Titiksha Basu, Albert Gruender, PhD, Christine Dierks, MD, Heike L Pahl, PhD

Blood (2015) 126 (23): 2825.

https://doi.org/10.1182/blood.V126.23.2825.2825

Published: 2015

Journal Articles

Growth Factor Receptor-Bound Protein 10 (Grb10) Regulates Hematopoietic Stem Cell Renewal

Xiao Yan, Heather A. Himburg, PhD, Phuong L. Doan, MD, Mamle Quarmyne, Nelson J. Chao, MD, John P. Chute, MD

Blood (2014) 124 (21): 248.

https://doi.org/10.1182/blood.V124.21.248.248

Published: 2014

Journal Articles

Identification of Wee1 and IGF-1R As Novel Therapeutic Targets for Mutant RAS-Driven Acute Leukemia By Combinatory Chemical Screens

Atsushi Nonami, MDPhD, Chen Zhao, PhD, Liu Qingsong, PhD, Kristen Cowens, Amanda L. Christie, Yongfei Chen, Martin Sattler, PhD, Kwok-Kin Wang, MDPhD, Nathanael S. Gray, PhD, James D. Griffin, MD, Ellen L. Weisberg, PhD

Blood (2014) 124 (21): 3502.

https://doi.org/10.1182/blood.V124.21.3502.3502

Published: 2014

Journal Articles

Integrated Analysis Of Genomic and Gene Expression Profiles In Follicular Lymphoma Reveals Subsets and Driver Genes Of Potential Microenvironmental Importance

Ondrej Havranek, MD PhD, Jason R. Westin, MD, Min Zhang, PhD, Seema Rawal, PhD, Larry W. Kwak, MD, PhD, Sattva S. Neelapu, MD, R. Eric Davis, MD

Blood (2013) 122 (21): 2487.

https://doi.org/10.1182/blood.V122.21.2487.2487

Published: 2013

NARROW

Paraoxonase 2 Enables Initiation of B-ALL By Subverting Metabolic Gatekeeper Functions

IGF1R-IRS1/2 Signaling Pathway Is a Potential Target for FLT3-Mutated Acute Myeloid Leukemia

Phospho-Proteomic Profiling of T-Cell Acute Lymphoblastic Leukemia Identifies Specific Kinase Activation Signatures That Can Predict Response to Targeted Therapy

Glycemic Control in Patients Treated with Tyrosine Kinase Inhibitors for Chronic Myeloid Leukemia: A Systematic Review

High IGF1R Expression Is Associated with Worse Prognosis in CLL and Impacts Response to PI3K-δ Inhibitor Treatment

Targeting Insulin-like Growth Factor/Insulin Receptor Signaling to Overcome JAK2 Inhibitor Persistence in Myeloproliferative Neoplasms

CDC37 As a Novel Target for the Treatment of NPM1-ALK Expressing Anaplastic Large Cell Lymphomas

Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function

Transcriptional Control of Glucose and Energy Supply Prevents Oncogenic Signaling and B Cell Transformation

Ponatinib Exerts Multiple Effects on Vascular Endothelial Cells: Possible Mechanisms and Explanations for the Adverse Vascular Events Seen in CML Patients Treated with Ponatinib

A Genetic Risk Score for Insulin Resistance Identify Patients with Chronic Myeloid Leukemia, Treated with Nilotinib, Developing Diabetes

B-Lymphoid Transcription Factors Restrict Glycolytic Energy Supply for Oncogenic Signaling

Melphalan Affects Genes Critical for Myeloma Survival, Homing, and Response to Cytokines and Chemokines

Ptdglc-Enriched Lipid Rafts Are a Novel Platform for Apoptosis Signaling in Human Neutrophilic Lineage Cells

Metformin Therapy and Survival in Multiple Myeloma Among US Veterans with Diabetes Mellitus

Growth Factor Receptor-Bound Protein 10 (Grb10) Regulates Hematopoietic Stem Cell (HSC) Self-Renewal Via Control of mTOR Signaling

Preclinical Analysis of Linsitinib for the Treatment of Polycythemia Vera

Growth Factor Receptor-Bound Protein 10 (Grb10) Regulates Hematopoietic Stem Cell Renewal

Identification of Wee1 and IGF-1R As Novel Therapeutic Targets for Mutant RAS-Driven Acute Leukemia By Combinatory Chemical Screens

Integrated Analysis Of Genomic and Gene Expression Profiles In Follicular Lymphoma Reveals Subsets and Driver Genes Of Potential Microenvironmental Importance

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American Society of Hematology

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ASH Publications

American Society of Hematology

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