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Journal Articles

Nicked β2-glycoprotein I binds angiostatin 4.5 (plasminogen kringle 1-5) and attenuates its antiangiogenic property

Hisako Nakagawa, Shinsuke Yasuda, Eiji Matsuura, Kazuko Kobayashi, Masahiro Ieko, Hiroshi Kataoka, Tetsuya Horita, Tatsuya Atsumi, Takao Koike
Journal: Blood
Blood (2009) 114 (12): 2553–2559.
https://doi.org/10.1182/blood-2008-12-190629
Published: 2009
Journal Articles

A Unique Recombinant Plasmin Molecule Lacking Kringles 2-5 Possesses Equivalent Hemostatic Safety as Full-Length Human Plasmin.

Victor J. Marder, MD, Valery Novokhatny, Steve Manyak, Theresa Gruber, Jennifer Hunt, John Bromirski, Abha Goyal, Philip Scuderi, Steve Petteway
Journal: Blood
Blood (2008) 112 (11): 2028.
https://doi.org/10.1182/blood.V112.11.2028.2028
Published: 2008
Journal Articles

Kringle 5 of human plasminogen, an angiogenesis inhibitor, induces both autophagy and apoptotic death in endothelial cells

Tri Minh Bui Nguyen, Indira V. Subramanian, Ameeta Kelekar, Sundaram Ramakrishnan
Journal: Blood
Blood (2007) 109 (11): 4793–4802.
https://doi.org/10.1182/blood-2006-11-059352
Published: 2007
Includes: Supplemental data
Journal Articles

Phosphatidylserine (PS) Binding Sites in Kringle Modules Regulate the Domain Organization and Conformation of Bovine Prothrombin.

Shalmali Sen, PhD, Mou Banerjee, Ph.D, Vishwanath Koppaka, Ph.D, Chaoming Zhou, Ph.D, Barry R. Lentz, Ph.D.
Journal: Blood
Blood (2005) 106 (11): 1952.
https://doi.org/10.1182/blood.V106.11.1952.1952
Published: 2005
Journal Articles

Kringle IV Encoding Domains in the Apo(a) Gene and Serum Lipoprotein(a) Level Do Not Contribute to Avascular Necrosis of Bone (AVN) in Acute Lymphoblastic Leukemia.

Désirée D.L. Bezemer, Robert D. van Beek, Jules P.P. Meijerink, Sabine M.P.F. de Muinck Keizer-Schrama, Rob Pieters, Marry M. van den Heuvel-Eibrink
Journal: Blood
Blood (2004) 104 (11): 4440.
https://doi.org/10.1182/blood.V104.11.4440.4440
Published: 2004
Journal Articles

Nicked β 2 -glycoprotein I: a marker of cerebral infarct and a novel role in the negative feedback pathway of extrinsic fibrinolysis

Clinical Trials & Observations
Shinsuke Yasuda, Tatsuya Atsumi, Masahiro Ieko, Eiji Matsuura, Kazuko Kobayashi, Junko Inagaki, Hisao Kato, Hideyuki Tanaka, Minoru Yamakado, Minoru Akino, Hisatoshi Saitou, Yoshiharu Amasaki, Satoshi Jodo, Olga Amengual, Takao Koike
Journal: Blood
Blood (2004) 103 (10): 3766–3772.
https://doi.org/10.1182/blood-2003-08-2712
Published: 2004
Journal Articles

The kringle stabilizes urokinase binding to the urokinase receptor

Khalil Bdeir, Alice Kuo, Bruce S. Sachais, Ann H. Rux, Yasmina Bdeir, Andrew Mazar, Abd Al-Roof Higazi, Douglas B. Cines
Journal: Blood
Blood (2003) 102 (10): 3600–3608.
https://doi.org/10.1182/blood-2003-03-0949
Published: 2003
Journal Articles

Tumor suppression induced by intratumor administration of adenovirus vector expressing NK4, a 4-kringle antagonist of hepatocyte growth factor, and naive dendritic cells

Toshiaki Kikuchi, Makoto Maemondo, Koh Narumi, Kunio Matsumoto, Toshikazu Nakamura, Toshihiro Nukiwa
Journal: Blood
Blood (2002) 100 (12): 3950–3959.
https://doi.org/10.1182/blood-2002-04-1096
Published: 2002
Journal Articles

Novel Interaction of Apolipoprotein(a) With β-2 Glycoprotein I Mediated by the Kringle IV Domain

Silvano Köchl, Friedrich Fresser, Eva Lobentanz, Gottfried Baier, Gerd Utermann
Journal: Blood
Blood (1997) 90 (4): 1482–1489.
https://doi.org/10.1182/blood.V90.4.1482
Published: 1997