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Ann H. Rux
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Journal Articles

Complement mediates binding and procoagulant effects of ultralarge HIT immune complexes

Sanjay Khandelwal, Ayiesha Barnes, Lubica Rauova, Amrita Sarkar, Ann H. Rux, Serge V. Yarovoi, S. Sergei Zaitsev, John D. Lambris, Sooho S. Myoung, Alexandra Johnson, Grace M. Lee, Madelaine Duarte, Mortimer Poncz, Gowthami M. Arepally, Douglas B. Cines
Journal: Blood
Blood (2021) 138 (21): 2106–2116.
https://doi.org/10.1182/blood.2020009487
Published: 2021
Includes: Supplemental data
Journal Articles

FcRn augments induction of tissue factor activity by IgG-containing immune complexes

Douglas B. Cines, Sergei Zaitsev, Lubica Rauova, Ann H. Rux, Victoria Stepanova, Sriram Krishnaswamy, Amrita Sarkar, M. Anna Kowalska, Guohua Zhao, Alan E. Mast, Laurence J. Blumberg, Keith R. McCrae, Mortimer Poncz, Jonathan J. Hubbard, Michal Pyzik, Richard S. Blumberg
Journal: Blood
Blood (2020) 135 (23): 2085–2093.
https://doi.org/10.1182/blood.2019001133
Published: 2020
Includes: Supplemental data
Journal Articles

Novel diagnostic assays for heparin-induced thrombocytopenia

Adam Cuker, Ann H. Rux, Jillian L. Hinds, May Dela Cruz, Serge V. Yarovoi, Isola A. M. Brown, Wei Yang, Barbara A. Konkle, Gowthami M. Arepally, Stephen P. Watson, Douglas B. Cines, Bruce S. Sachais
Journal: Blood
Blood (2013) 121 (18): 3727–3732.
https://doi.org/10.1182/blood-2013-01-479576
Published: 2013
Journal Articles

Novel Diagnostic Assays for Heparin-Induced Thrombocytopenia

Adam Cuker, MD, MS, Ann H Rux, PhD, Jillian L Hinds, BS, May Dela Cruz, MD, Serge Yarovoi, PhD, Wei Yang, PhD, Barbara A. Konkle, MD, Gowthami M Arepally, MD, Steve P Watson, PhD, Douglas B. Cines, Bruce S Sachais, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 267.
https://doi.org/10.1182/blood.V120.21.267.267
Published: 2012
Journal Articles

Dynamic antibody-binding properties in the pathogenesis of HIT

Bruce S. Sachais, Rustem I. Litvinov, Serge V. Yarovoi, Lubica Rauova, Jillian L. Hinds, Ann H. Rux, Gowthami M. Arepally, Mortimer Poncz, Adam Cuker, John W. Weisel, Douglas B. Cines
Journal: Blood
Blood (2012) 120 (5): 1137–1142.
https://doi.org/10.1182/blood-2012-01-407262
Published: 2012
Includes: Supplemental data
Journal Articles

Rational design and characterization of platelet factor 4 antagonists for the study of heparin-induced thrombocytopenia

Bruce S. Sachais, Ann H. Rux, Douglas B. Cines, Serge V. Yarovoi, Lee I. Garner, Stephen P. Watson, Jillian L. Hinds, John J. Rux
Journal: Blood
Blood (2012) 119 (25): 5955–5962.
https://doi.org/10.1182/blood-2012-01-406801
Published: 2012
Journal Articles

Rational Design and Characterization of Platelet Factor 4 Antagonists

Bruce S Sachais, MD, PhD, Ann H Rux, PhD, Jillian L Hinds, BS, John J Rux, PhD
Journal: Blood
Blood (2010) 116 (21): 724.
https://doi.org/10.1182/blood.V116.21.724.724
Published: 2010
Journal Articles

Low Density Lipoprotein Apheresis Reduces PF4 on the Surface of Platelets: a Possible Protective Mechanism Against HIT

Yvette C Tanhehco, MD, PhD, Ann H Rux, PhD, Bruce S Sachais, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2530.
https://doi.org/10.1182/blood.V116.21.2530.2530
Published: 2010
Journal Articles

The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow

Ping Zhang, Weilan Pan, Ann H. Rux, Bruce S. Sachais, X. Long Zheng
Journal: Blood
Blood (2007) 110 (6): 1887–1894.
https://doi.org/10.1182/blood-2007-04-083329
Published: 2007
Journal Articles

The Middle and Distal Carboxyl Terminal Domains of ADAMTS13 Are Critical for Docking ADAMTS13 to von Willebrand Factor.

Ping Zhang, MD, Pan Weilan, MD, Ann H. Rux, PhD, Bruce S. Sachais, MD, PhD, X. Long Zheng, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 332.
https://doi.org/10.1182/blood.V108.11.332.332
Published: 2006
Journal Articles

Endothelial expression of E-selectin is induced by the platelet-specific chemokine platelet factor 4 through LRP in an NF-κB–dependent manner

Guangyao Yu, Ann H. Rux, Peihong Ma, Khalil Bdeir, Bruce S. Sachais
Journal: Blood
Blood (2005) 105 (9): 3545–3551.
https://doi.org/10.1182/blood-2004-07-2617
Published: 2005
Journal Articles

The Platelet Specific Chemokine Platelet Factor 4 Induces Expression of E-Selectin in an NF-κ B Dependent Manner.

Bruce S. Sachais, MD, PhD, Peihong Ma, BS, Ann H. Rux, PhD, Guangyao Yu, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 3908.
https://doi.org/10.1182/blood.V104.11.3908.3908
Published: 2004
Journal Articles

The kringle stabilizes urokinase binding to the urokinase receptor

Khalil Bdeir, Alice Kuo, Bruce S. Sachais, Ann H. Rux, Yasmina Bdeir, Andrew Mazar, Abd Al-Roof Higazi, Douglas B. Cines
Journal: Blood
Blood (2003) 102 (10): 3600–3608.
https://doi.org/10.1182/blood-2003-03-0949
Published: 2003