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Manu Thomas Kalathottukaren
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Journal Articles

Destabilization of PF4-antigenic complexes in heparin-induced thrombocytopenia

Lubica Rauova, Khalil Bdeir, Ann H Rux, Manu Thomas Kalathottukaren, Jenna Oberg, Chanel C. La, David Thiam En Lim, Vincent M Hayes, Gavin T. Koma, Amrita Sarkar, Mortimer Poncz, Jayachandran N Kizhakkedathu, Douglas B. Cines
Journal: Blood
Blood blood.2024025653.
https://doi.org/10.1182/blood.2024025653
Published: 2025
Includes: Supplemental data
Journal Articles

Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA

Manu Thomas Kalathottukaren, Libin Abraham, Piyushkumar R. Kapopara, Benjamin F. L. Lai, Rajesh A. Shenoi, Federico I. Rosell, Edward M. Conway, Edward L. G. Pryzdial, James H. Morrissey, Charles A. Haynes, Jayachandran N. Kizhakkedathu
Journal: Blood
Blood (2017) 129 (10): 1368–1379.
https://doi.org/10.1182/blood-2016-10-747915
Published: 2017
Includes: Supplemental data
Journal Articles

A Universal Heparin Antidote with Negligible Effect on Fibrin(ogen) and Plasma Coagulation

Manu Thomas Kalathottukaren, PhDcandidate, Rajesh A Shenoi, PhD, Lai FL Benjamin, MSc, Fred Rosell, PhD, Jayachandran N Kizhakkedathu, PhD, Edward L.G. Pryzdial, PhD
Journal: Blood
Blood (2014) 124 (21): 4231.
https://doi.org/10.1182/blood.V124.21.4231.4231
Published: 2014
Journal Articles

Nontoxic polyphosphate inhibitors reduce thrombosis while sparing hemostasis

Richard J. Travers, Rajesh A. Shenoi, Manu Thomas Kalathottukaren, Jayachandran N. Kizhakkedathu, James H. Morrissey
Journal: Blood
Blood (2014) 124 (22): 3183–3190.
https://doi.org/10.1182/blood-2014-05-577932
Published: 2014
Includes: Supplemental data