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Jenna Oberg
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Journal Articles

Both platelet factor 4 (PF4) and b2-glycoprotein I (b2GPI) bind to von Willebrand factor (VWF) and inhibit ADAMTS13 cleavage: Mechanistic and clinical implications in thrombotic thrombocytopenic purpura (TTP)

Free
Amrita Sarkar, Khalil Bdeir, Chloe Ro, Jenna Oberg, X. Long Zheng, Gow Arepally, Douglas Cines, Lubica Rauova, Mortimer Poncz
Journal: Blood
Blood (2025) 146 (Supplement 1): 4876.
https://doi.org/10.1182/blood-2025-4876
Published: 2025
Journal Articles

Platelet-activating antibodies to the chemokine, platelet factor 4, in cerebral malaria differ from those in heparin-induced thrombocytopenia and vaccine-induced thrombotic thrombocytopenia.

Free
Lubica Rauova, Iset Vera, Jenna Oberg, Ruth Namazzi, Marcus Shackleford, Karl Seydel, Douglas Cines, Chandy John, Kami Kim, Mortimer Poncz
Journal: Blood
Blood (2025) 146 (Supplement 1): 4870.
https://doi.org/10.1182/blood-2025-4870
Published: 2025
Journal Articles

Platelet factor 4 (PF4) modulates endothelial cell antimicrobial activity to enhance bacterial clearance and improve sepsis outcomes

Free
Anh Ngo, Weronika Ortmann, Abigail Skidmore, Hyunjun Kim, Jenna Oberg, Amrita Sarkar, Veronica Bochenek, Nate Levine, Lubica Rauova, Irina Chernysh, Zachary Martinez, Caroline Diorio, Mark Goulian, Victor Nizet, Mortimer Poncz, Kandace Gollomp
Journal: Blood
Blood (2025) 146 (Supplement 1): 1322.
https://doi.org/10.1182/blood-2025-1322
Published: 2025
Journal Articles

Destabilization of PF4-antigenic complexes in heparin-induced thrombocytopenia

Available to Purchase
Lubica Rauova, Khalil Bdeir, Ann H. Rux, Manu Thomas Kalathottukaren, Jenna Oberg, Chanel C. La, David T. E. Lim, Vincent Hayes, Gavin T. Koma, Amrita Sarkar, Mortimer Poncz, Jayachandran N. Kizhakkedathu, Douglas B. Cines
Journal: Blood
Blood (2025) 145 (25): 3030–3040.
https://doi.org/10.1182/blood.2024025653
Published: 2025
Includes: Supplemental data
Journal Articles

Platelet Factor 4 Enhances Endothelial Cell Antimicrobial Activity in Vitro and Promotes Bacterial Clearance In Vivo , Improving Sepsis Outcomes

Free
Anh T.P. Ngo, Veronica Bochenek, Hyunjun Kim, Nate Levine, Samir Maarouf, Jenna Oberg, Manuela Roggiani, Amrita Sarkar, Lubica Rauova, Caroline Diorio, Zachary Martinez, Mark Goulian, Mortimer Poncz, Victor Nizet, Kandace Gollomp
Journal: Blood
Blood (2024) 144 (Supplement 1): 1231.
https://doi.org/10.1182/blood-2024-211717
Published: 2024
Journal Articles

A Novel Adenovirus (Adv)-Vaccinated Murine Model Simulates the Prothrombotic Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT) Clinical Disorder

Free
Lubica Rauova, Jenna Oberg, Nate Levine, Khalil Bdeir, Douglas B. Cines, Sarah Gilbert, Mortimer Poncz, Gowthami Arepally
Journal: Blood
Blood (2023) 142 (Supplement 1): 2631.
https://doi.org/10.1182/blood-2023-186729
Published: 2023