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Journal Articles

Cell Adhesion of ALL to Stromal Cells May Mediate CAR T-Cell Resistance: A Novel Escape Mechanism for Immunotherapy

Hye Na Kim, Enzi Jiang, MD PhD, Ruan Yongsheng, MD, Heather Ogana, Nour Abdel-Azim, Justin Le, BS, Annie Luong, Halvard Bonig, MD, Nabil Ahmed, MD, Moghimi Babak, MD, Michael A. Pulsipher, MD, Deepa Bhojwani, MD, Alan S. Wayne, MD, Chintan Parekh, MBBS, Hisham Abdel-Azim, Nora Heisterkamp, Yong-Mi Kim, MD MPH, PhD

Blood (2019) 134 (Supplement_1): 2623.

https://doi.org/10.1182/blood-2019-132131

Published: 2019

Journal Articles

Progressive Multifocal Leukoencephalopathy in a Patient with Multiple Myeloma Receiving Daratumumab and Pomalidomide

Jorge Monge, MD, Jorge Contreras, MD, Sarah Elsoukkary, MD, Jin Guo, MD, Art Perry, PA, Robin S. Solomon, Kari Flicker, BS, David S Jayabalan, MSc, Morton Coleman, MD, Adriana C. Rossi, MDMSc, Rebecca Harris, MD, Markus Plate, MD, Joerg-Patrick Stuebgen, MB, ChB, MD, Ruben Niesvizky, MD

Blood (2019) 134 (Supplement_1): 4876.

https://doi.org/10.1182/blood-2019-122134

Published: 2019

Journal Articles

Phase II Trial of Natalizumab (Tysabri®) with Corticosteroids As Initial Treatment of Gastrointestinal Acute Graft Versus Host Disease

Natasha Kekre, MD FRCPC, Haesook T Kim, PhD, Vincent T Ho, MD, Yikun Guo, Umair Mahmood, Wafae Belatreche, John Koreth, MBBS, DPhil, Philippe Armand, MD PhD, Sarah Nikiforow, Edwin Alyea, III, MD, Prashant Nageshwar, MD, Brett Glotzbecker, Areej El-Jawahri, MD, Robert J. Soiffer, MD, Joseph H. Antin, MD, Yi-Bin Chen, MD, Corey S. Cutler, MD MPH

Blood (2017) 130 (Supplement 1): 3252.

https://doi.org/10.1182/blood.V130.Suppl_1.3252.3252

Published: 2017

Journal Articles

Autologous Hematopoietic Stem Cell Transplantation (AHSCT) in Advanced, Treatment Refractory Multiple Sclerosis (MS) — a Phase II Clinical Trial

Jennifer Massey, MBBS, John Moore, MDFRACP,FRCPA,, Ian Sutton, Chun Kei Kris Ma, PhDMBBS, Sam Milliken, FRACP,FRCPA,MBBS, David Ma

Blood (2017) 130 (Supplement 1): 4553.

https://doi.org/10.1182/blood.V130.Suppl_1.4553.4553

Published: 2017

Journal Articles

CAR T Cell Relapse CD19 Negative ALL Cells Express Integrins and Integrin Blockade Can Prolong Survival In Vivo

Hye Na Kim, Solah Lee, Kristen Fousek, BS, MS, Shuangyue Li, Anne Kim, Junji Watanabe, PhD, Halvard Bonig, MD MA, Nabil Ahmed, MD, Hisham Abdel-Azim, Nora Heisterkamp, PhD, Yong-Mi Kim, MD MPH, PhD

Blood (2017) 130 (Supplement 1): 2601.

https://doi.org/10.1182/blood.V130.Suppl_1.2601.2601

Published: 2017

Journal Articles

AVA4746, an Orally Available, Clinical Grade Antagonist of Integrin Alpha 4, Sensitizes Pre-B Cell Acute Lymphoblastic Leukemia to Chemotherapy

Yongsheng Ruan, MD, Eun Ji Gang, Hye-Na Kim, Chintan Parekh, MBBS, Hisham Abdel-Azim, MD, Deepa Bhojwani, MD, Alan S. Wayne, MD, Yong-Mi Kim, MD PhD MPH

Blood (2016) 128 (22): 2765.

https://doi.org/10.1182/blood.V128.22.2765.2765

Published: 2016

Journal Articles

Selective Inhibition of α4β1 Integrin (VLA-4) Mitigates GvHD

Bader Alahmari, MD, Jaebok Choi, PhD, Matthew L Cooper, PhD, Kiran R. Vij, MD, Julie Ritchey, Bing Wang, John F DiPersio, MD PhD

Blood (2016) 128 (22): 3344.

https://doi.org/10.1182/blood.V128.22.3344.3344

Published: 2016

Journal Articles

Adoptive T Cell Therapy for Polyomaviral Infections and Related Diseases

Dhana Chinnasamy, PhD, Greg Whitehill, BS, Keyvan Keyvanfar, BS, Isaac Brownell, MD PhD, Christopher Buck, PhD, Pawel Muranski, MD, Austin John Barrett, MDFRCP,FRCPath

Blood (2015) 126 (23): 4294.

https://doi.org/10.1182/blood.V126.23.4294.4294

Published: 2015

Journal Articles

Natalizumab Blocks VLA-4 Mediated Red Blood Cell Adhesion and Is a Potential Therapy for Sickle Cell Disease

Patrick C. Hines, MD PhD, Sriram Krishnamoorthy, PhD, Jennell White, PhD, Dipti Gupta, MS, Arjan van der Flier, PhD, Moira M. Lancelot, MD, Robert T. Peters, PhD BS, Haiyan Jiang, PhD, William E Hobbs, MD PhD, David R. Light, PhD

Blood (2014) 124 (21): 221.

https://doi.org/10.1182/blood.V124.21.221.221

Published: 2014

Journal Articles

Development and characterization of a physiologically relevant model of lymphocyte migration in chronic lymphocytic leukemia

Elisabeth Walsby, Andrea Buggins, Stephen Devereux, Ceri Jones, Guy Pratt, Paul Brennan, Chris Fegan, Chris Pepper

Blood (2014) 123 (23): 3607–3617.

https://doi.org/10.1182/blood-2013-12-544569

Published: 2014

Includes: Supplemental data

Journal Articles

Allogeneic Hematopoietic Stem Cell Transplantation For Severe Neuromyelitis Optica

Blood (2013) 122 (21): 5539.

https://doi.org/10.1182/blood.V122.21.5539.5539

Published: 2013

Journal Articles

VLA4 Blockade In Acute Myeloid Leukemia

Yao-Te Hsieh, Enzi Jiang, MD, PhD, Jennifer Pham, Hye-Na Kim, Hisham Abdel-Azim, MD, Sajad Khazal, MD, Gesine Bug, MD, PhD, Gabriele Spohn, Ph.D., Halvard Bonig, MD, MA, Yong-Mi Kim, MD, MPH, PhD

Blood (2013) 122 (21): 3944.

https://doi.org/10.1182/blood.V122.21.3944.3944

Published: 2013

Journal Articles

Characterization Of a Novel In Vitro Circulation System Designed To Model The Migration Of Primary CLL Cells Across The Vascular Endothelium

Elisabeth J Walsby, Andrea GS Buggins, Ph.D., Stephen Devereux, FRCP, FRCPath, PhD, Paul Brennan, Chris Fegan, Chris Pepper

Blood (2013) 122 (21): 667.

https://doi.org/10.1182/blood.V122.21.667.667

Published: 2013

Journal Articles

The Small Molecule Inhibitor of VLA4 TBC3486 Sensitizes Resistant ALL to Chemotherapy

Yao-Te Hsieh, Eun Ji Gang, MD, PhD, Halvard Bonig, MD, MA, Ronald J Biediger, PhD, Peter Vanderslice, PhD, Yong-Mi Kim, MD, MPH, PhD

Blood (2012) 120 (21): 1500.

https://doi.org/10.1182/blood.V120.21.1500.1500

Published: 2012

Journal Articles

Therapeutic Plasma Exchange for Progressive Multifocal Leukoencephalopathy Related to Multiple Sclerosis Therapy with Natalizumab

Eimad Zakariya, MD, Mariko Yabe, MD, Armistead Williams, MD, Randy L. Levine, MD, Mark T Friedman, DO

Blood (2012) 120 (21): 4386.

https://doi.org/10.1182/blood.V120.21.4386.4386

Published: 2012

Journal Articles

Treatment of Severe Relapsing-Remitting Multiple Sclerosis with High-Dose Immunosuppressive Therapy and Autologous Hematopoietic Cell Transplantation: 2-Year Follow-up Results of the HALT MS Clinical Trial (Immune Tolerance Network: ITN033AI)

Richard A. Nash, MD, George J. Hutton, MD, Michael K Racke, MD, Uday R. Popat, M.D., Steven M. Devine, MD, George E. Georges, MD, Linda M. Griffith, MD, PhD, Paolo A Muraro, MD, Harry Openshaw, MD, Peter H. Sayre, MD, PhD, Olaf Stuve, MD, Douglas L Arnold, MD, Meagan Spychala, Noha Lim, PhD, Sachin Malhotra, PhD, Deborah Phippard, PhD, Annette Wundes, MD, George H Kraft, MD, James D Bowen, MD

Blood (2012) 120 (21): 962.

https://doi.org/10.1182/blood.V120.21.962.962

Published: 2012

Journal Articles

Immune Defects of B- and T-Cell Compartments in Natalizumab-Induced Progressive Multifocal Leukoencephalopathy,

Alessandra Sottini, Ruggero Capra, Cinzia Zanotti, Marco Chiarini, Federico Serana, Cinzia Lamorgese, Marina Motta, MD, Doris Ricotta, Luigi Caimi, Luisa Imberti

Blood (2011) 118 (21): 3228.

https://doi.org/10.1182/blood.V118.21.3228.3228

Published: 2011

Journal Articles

Interactions with the Microenvironment Protect Lymphoma B-Cells From Rituximab Induced Apoptosis and Could Represent a Therapeutic Target

Marek Mraz, MD, Clive S. Zent, MD, Amy K Church, Nisar A Baig, Diane F. Jelinek, PhD, Xiaosheng Wu, PhD, Sarka Pospisilova, Dr, PhD, Stephen M. Ansell, MD, PhD, Anne J. Novak, PhD, Thomas E. Witzig, MD, Grzegorz S. Nowakowski, MD

Blood (2010) 116 (21): 3115.

https://doi.org/10.1182/blood.V116.21.3115.3115

Published: 2010

Journal Articles

Long-Term Effects of In Vivo Administration of An Anti-VLA-4 Antibody (natalizumab) on Mobilization of Committed and Primitive Hematopoietic Progenitor Cells In Humans

Jorge Domenech, MD, PhD, Julien Goustille, PharmD, Maud Pallix, MD, Zakia Bekhechi, PharmD, Elfi Ducrocq, Michel Degenne, PharmD, Olivier Herault, MD, PhD, Gilles Thibault, PharmD, Anne-Marie Guennoc, MD, Christian Binet, MD

Blood (2010) 116 (21): 2264.

https://doi.org/10.1182/blood.V116.21.2264.2264

Published: 2010

Journal Articles

Adjuvant CD49d Blockade Eradicates Chemoresistant ALL

Yao-Te Hsieh, Eugene Park, Enzi Jiang, MD, PhD, Katrin Dauber, Doreen Chudziak, Paul Schaefer, Lars Klemm, Carlton Scharman, Eun-Suk Kang, MD, PhD, Hong-Hoe Koo, MD, PhD, Mignon L. Loh, M.D., Wolf Karsten Hofmann, MD, PhD, Nora Heisterkamp, Markus Muschen, MD, Hiroyuki Shimada, MD, Halvard Bonig, MD, MA, Yong-Mi Kim, MD, MPH

Blood (2010) 116 (21): 869.

https://doi.org/10.1182/blood.V116.21.869.869

Published: 2010

NARROW

Cell Adhesion of ALL to Stromal Cells May Mediate CAR T-Cell Resistance: A Novel Escape Mechanism for Immunotherapy

Progressive Multifocal Leukoencephalopathy in a Patient with Multiple Myeloma Receiving Daratumumab and Pomalidomide

Phase II Trial of Natalizumab (Tysabri®) with Corticosteroids As Initial Treatment of Gastrointestinal Acute Graft Versus Host Disease

Autologous Hematopoietic Stem Cell Transplantation (AHSCT) in Advanced, Treatment Refractory Multiple Sclerosis (MS) — a Phase II Clinical Trial

CAR T Cell Relapse CD19 Negative ALL Cells Express Integrins and Integrin Blockade Can Prolong Survival In Vivo

AVA4746, an Orally Available, Clinical Grade Antagonist of Integrin Alpha 4, Sensitizes Pre-B Cell Acute Lymphoblastic Leukemia to Chemotherapy

Selective Inhibition of α4β1 Integrin (VLA-4) Mitigates GvHD

Adoptive T Cell Therapy for Polyomaviral Infections and Related Diseases

Natalizumab Blocks VLA-4 Mediated Red Blood Cell Adhesion and Is a Potential Therapy for Sickle Cell Disease

Development and characterization of a physiologically relevant model of lymphocyte migration in chronic lymphocytic leukemia

Allogeneic Hematopoietic Stem Cell Transplantation For Severe Neuromyelitis Optica

VLA4 Blockade In Acute Myeloid Leukemia

Characterization Of a Novel In Vitro Circulation System Designed To Model The Migration Of Primary CLL Cells Across The Vascular Endothelium

The Small Molecule Inhibitor of VLA4 TBC3486 Sensitizes Resistant ALL to Chemotherapy

Therapeutic Plasma Exchange for Progressive Multifocal Leukoencephalopathy Related to Multiple Sclerosis Therapy with Natalizumab

Treatment of Severe Relapsing-Remitting Multiple Sclerosis with High-Dose Immunosuppressive Therapy and Autologous Hematopoietic Cell Transplantation: 2-Year Follow-up Results of the HALT MS Clinical Trial (Immune Tolerance Network: ITN033AI)

Immune Defects of B- and T-Cell Compartments in Natalizumab-Induced Progressive Multifocal Leukoencephalopathy,

Interactions with the Microenvironment Protect Lymphoma B-Cells From Rituximab Induced Apoptosis and Could Represent a Therapeutic Target

Long-Term Effects of In Vivo Administration of An Anti-VLA-4 Antibody (natalizumab) on Mobilization of Committed and Primitive Hematopoietic Progenitor Cells In Humans

Adjuvant CD49d Blockade Eradicates Chemoresistant ALL

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American Society of Hematology

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