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Journal Articles

An intestinal organoid–based platform that recreates susceptibility to T-cell–mediated tissue injury

Blood (2020) 135 (26): 2388–2401.

https://doi.org/10.1182/blood.2019004116

Published: 2020

Includes: Supplemental data

Journal Articles

T-Cell Derived Interferon Gamma Directly Targets Intestinal Epithelium to Induce Stem Cell Apoptosis in GI Gvhd

Shuichiro Takashima, MD PhD, Maria L. Martin, PhD, Suze A. Jansen, Ya-Yuan Fu, PhD, Anastasiya Egorova, Chen Liu, MD PhD, Richard Kolesnick, MD, Caroline A. Lindemans, MD, Alan M. Hanash, MD PhD

Blood (2019) 134 (Supplement_1): 585.

https://doi.org/10.1182/blood-2019-130811

Published: 2019

Journal Articles

Acute Myeloid Leukemia (AML) in a 3D Bone Marrow Niche Showed High Performance for in Vitro and In Vivo Drug Screenings

Giulia Borella, Ambra Da Ros, Elena Porcù, PhD, Claudia Tregnago, PhD, Maddalena Benetton, Valeria Bisio, PhD, Elisabetta Campodoni, Silvia Panseri, PhD, Monica Sandri, PhD, Monica Montesi, PhD, Stefano Cairo, PhD, Franco Locatelli, MD PhD, Martina Pigazzi, PhD

Blood (2019) 134 (Supplement_1): 544.

https://doi.org/10.1182/blood-2019-128382

Published: 2019

Journal Articles

Mapping MALT1 Signaling Connectivity Unveils Novel B-Cell Feedback Mechanisms Directing Assembly of Potent Anti-Lymphoma Regimens

Lorena Fontan, PhD, Matthew Durant, Rebecca Goldstein, PhD, Matthew R Teater, PhD, Gabriella Casalena, PhD, Min Xia, PhD, Jimmy Wilson, Ilkay Us, Giorgio Inghirami, MD, Ari Melnick, MD

Blood (2019) 134 (Supplement_1): 173.

https://doi.org/10.1182/blood-2019-130516

Published: 2019

Journal Articles

Combined EZH2 and BCL2 Inhibitors As Precision Therapy for Genetically Defined DLBCL Subtypes

Destini Gibbs, Herman Van Besien, BA, Stephenson Regan, Ankur Singh, PhD, Matthew Teater, Ethel Cesarman, MD PhD, Ari Melnick, MD, Lisa Giulino Roth, MD

Blood (2019) 134 (Supplement_1): 304.

https://doi.org/10.1182/blood-2019-126790

Published: 2019

Journal Articles

Blocking JAK1/JAK2 While Sparing JAK3 Not Only Prevents GvHD but Also Promotes Damaged Tissue Repair

Kidist Ashami, BA, Sena Kim, PhD, Ravi Vij, MBBS, Julie K. Ritchey, Srikanth Santhanam, PhD, Sora Lim, MS, Sarah Peterson, Matthew Ciorba, MD, John F. DiPersio, MD PhD, Jaebok Choi, PhD

Blood (2019) 134 (Supplement_1): 4420.

https://doi.org/10.1182/blood-2019-126167

Published: 2019

Journal Articles

Microbial-Derived Metabolites Drive Protective Type-I Interferon Responses in Models of Gut Epithelial Damage and Limit Graft-Versus-Host Disease

Erik Thiele Orberg, MD PhD, Sascha Göttert, Hendrik Poeck, MD

Blood (2019) 134 (Supplement_1): 3207.

https://doi.org/10.1182/blood-2019-125850

Published: 2019

Journal Articles

Follicular Lymphoma Organoids for Investigating the Tumor Microenvironment

Lisa E Wagar, PhD, Brian Sworder, MD PhD, Michael S. Khodadoust, MD PhD, Mark M Davis, PhD, Ash A. Alizadeh, MD PhD

Blood (2019) 134 (Supplement_1): 2799.

https://doi.org/10.1182/blood-2019-131192

Published: 2019

Journal Articles

Guided Polarization of iPSC-Derived CD4SP Helper T Cells By CRISPR/Cas9-Based Genome-Editing

Hisashi Yano, MD, Tokuyuki Shinohara, PhD, Keiko Koga, PhD, Shoichi Iriguchi, PhD, Yasuyuki Miyake, Xuewei Song, Megumi Tada, Yoshiaki Kassai, PhD, Hitoshi Kiyoi, MD PhD, Shin Kaneko, MD PhD

Blood (2019) 134 (Supplement_1): 1937.

https://doi.org/10.1182/blood-2019-122193

Published: 2019

Journal Articles

Development of Bio-Artificial Micro-Vessels with Immunosuppressive Capacities: A Hope for Future Transplantations and Organoids

Sina Naserian, PhD, Mohamed Essameldin Abdelgawad, PhD, Julie Lachaux, Master, Nassim Arouche, Master, Fanny Loisel, Mazdak Afshar, Master, Gilgueng Hwang, PhD, Mercier Olaf, MD PhD, Anne-Marie Haghiri-Gosnet, PhD, Georges Uzan, PhD

Blood (2019) 134 (Supplement_1): 3610.

https://doi.org/10.1182/blood-2019-121395

Published: 2019

Journal Articles

The Innate Immune Sensor Sting Regulates Intestinal Inflammation and GVHD after Allogeneic Hematopoietic Stem Cell Transplantation in Knock-out and Human Allele Knock-in Recipient Mice

Cameron S. Bader, BS, Henry Barreras, MPH, Casey O. Lightbourn, MS, Sabrina Copsel, PhD, Jeonghyun Ahn, PhD, Glen N. Barber, PhD, Lei Jin, PhD MSc, Robert B. Levy, PhD

Blood (2018) 132 (Supplement 1): 65.

https://doi.org/10.1182/blood-2018-99-109999

Published: 2018

Journal Articles

Enhancing a Wnt-Telomere Feedback Loop Restores Intestinal Stem Cell Function in Dyskeratosis Congenita

Christopher Lengner

Blood (2018) 132 (Supplement 1): SCI-30.

https://doi.org/10.1182/blood-2018-99-109480

Published: 2018

Journal Articles

Developing the Next Generation of iPSC Cell-Based Immunotherapies

Raul Vizcardo, PhD, Nicholas Donald Klemen, MD, Rafiqul Islam, PhD, Devikala Gurusamy, PhD, Naritaka Tamaoki, MD, PhD, Li Jia, PhD, Zhiya Yu, PhD, Amanda N Hennings, PhD, Takuya Maeda, MD, Marta Bosch-Marce, PhD, Meghan L Good, MD, Svetlana Pack, PhD, David F. Stroncek, Francis A Flomerfelt, PhD, Michael J Kruhlak, PhD, Nicholas Phillip Restifo, MD

Blood (2018) 132 (Supplement 1): 3707.

https://doi.org/10.1182/blood-2018-99-118593

Published: 2018

Journal Articles

Engineering Regenerative Thymic Tissues to Restore Long-Term T Cell Lymphopoiesis

Hui Gai, MD, Rafa Gras~Pena, PhD, Yogendra Verma, MS, Vincent Fateh, BS, Kazuya Ikeda, MD, Beruh Dejene, MS, Dullei Min, Jing Wang, MD, Tomek Swigut, PhD, Ken I. Weinberg, MD, Georg A. Hollander, MD, Sarah Heilshorn, PhD, Maria-Grazia Roncarolo, MD, Vittorio Sebastiano, PhD, Katja G. Weinacht, MD PhD

Blood (2018) 132 (Supplement 1): 5092.

https://doi.org/10.1182/blood-2018-99-117499

Published: 2018

Journal Articles

Baricitinib Prevents and Treats GvHD through Both Immune Modulation and Enhancement of Tissue Repair

Kidist Ashami, BA, Kiran R. Vij, MD, Julie Ritchey, Srikanth Santhanam, PhD, Karl W. Staser, MD PhD, Sora Lim, Sena Kim, Matthew L. Cooper, PhD, Feng Gao, PhD, Matthew Ciorba, John F. DiPersio, MD PhD, Jaebok Choi, PhD

Blood (2018) 132 (Supplement 1): 3311.

https://doi.org/10.1182/blood-2018-99-119470

Published: 2018

Journal Articles

Heat Shock Factor 1 Reprograms the DLBCL Microenvironment to Evade Immune Surveillance and Support Tumor Growth

Jude M Phillip, DPhil, Maria Nieves Calvo Vidal, PhD, Maria Victoria Revuelta, PhD, Nahuel Zamponi, PhD, Stephen Sloan, Benet Pera Gresely, PhD, Tharu Fernando, PhD, Wayne Tam, MD PhD, Giorgio Inghirami, MD, Lawrence Bonassar, PhD, Ari M. Melnick, MD, Leandro Cerchietti, MD

Blood (2018) 132 (Supplement 1): 2854.

https://doi.org/10.1182/blood-2018-99-117774

Published: 2018

Journal Articles

In Vitro Generation of Human Pluripotent Stem Cell-Derived T Cells for Immunotherapy

Amélie Montel-Hagen, PhD, Christopher S. Seet, MD, Suwen Li, Brent Chick, Patrick Chang, Yuhua Zhu, Chongbin He, Shawn Lopez, Gay M. Crooks, MD

Blood (2017) 130 (Supplement 1): 691.

https://doi.org/10.1182/blood.V130.Suppl_1.691.691

Published: 2017

Journal Articles

Artificial Thymic Organoids Permit Allelic Exclusion and Efficient Generation of Naïve TCR-Engineered T-Cells from Human Hematopoietic Stem Cells In Vitro

Christopher S Seet, Chongbin He, Michael Bethune, Suwen Li, Brent Chick, Eric Gschweng, Yuhua Zhu, Kenneth Kim, David Baltimore, Donald B Kohn, Amelie Montel-Hagen, Gay M Crooks

Blood (2016) 128 (22): 4553.

https://doi.org/10.1182/blood.V128.22.4553.4553

Published: 2016

Journal Articles

Models of Pluripotent and Somatic Stem Cells to Study Tissue-Specific Sensitivities in Fanconi Anemia

Timothy Michael Chlon, PhD, Susanne I Wells, PhD, Sonya Ruiz-Torres, Matthew Kuhar, James M Wells, PhD

Blood (2015) 126 (23): 168.

https://doi.org/10.1182/blood.V126.23.168.168

Published: 2015

Journal Articles

RIG-I-Induced Type I IFNs Promote Regeneration of the Intestinal Stem Cell Compartment during Acute Tissue Damage

Blood (2015) 126 (23): 3072.

https://doi.org/10.1182/blood.V126.23.3072.3072

Published: 2015

NARROW

An intestinal organoid–based platform that recreates susceptibility to T-cell–mediated tissue injury

T-Cell Derived Interferon Gamma Directly Targets Intestinal Epithelium to Induce Stem Cell Apoptosis in GI Gvhd

Acute Myeloid Leukemia (AML) in a 3D Bone Marrow Niche Showed High Performance for in Vitro and In Vivo Drug Screenings

Mapping MALT1 Signaling Connectivity Unveils Novel B-Cell Feedback Mechanisms Directing Assembly of Potent Anti-Lymphoma Regimens

Combined EZH2 and BCL2 Inhibitors As Precision Therapy for Genetically Defined DLBCL Subtypes

Blocking JAK1/JAK2 While Sparing JAK3 Not Only Prevents GvHD but Also Promotes Damaged Tissue Repair

Microbial-Derived Metabolites Drive Protective Type-I Interferon Responses in Models of Gut Epithelial Damage and Limit Graft-Versus-Host Disease

Follicular Lymphoma Organoids for Investigating the Tumor Microenvironment

Guided Polarization of iPSC-Derived CD4SP Helper T Cells By CRISPR/Cas9-Based Genome-Editing

Development of Bio-Artificial Micro-Vessels with Immunosuppressive Capacities: A Hope for Future Transplantations and Organoids

The Innate Immune Sensor Sting Regulates Intestinal Inflammation and GVHD after Allogeneic Hematopoietic Stem Cell Transplantation in Knock-out and Human Allele Knock-in Recipient Mice

Enhancing a Wnt-Telomere Feedback Loop Restores Intestinal Stem Cell Function in Dyskeratosis Congenita

Developing the Next Generation of iPSC Cell-Based Immunotherapies

Engineering Regenerative Thymic Tissues to Restore Long-Term T Cell Lymphopoiesis

Baricitinib Prevents and Treats GvHD through Both Immune Modulation and Enhancement of Tissue Repair

Heat Shock Factor 1 Reprograms the DLBCL Microenvironment to Evade Immune Surveillance and Support Tumor Growth

In Vitro Generation of Human Pluripotent Stem Cell-Derived T Cells for Immunotherapy

Artificial Thymic Organoids Permit Allelic Exclusion and Efficient Generation of Naïve TCR-Engineered T-Cells from Human Hematopoietic Stem Cells In Vitro

Models of Pluripotent and Somatic Stem Cells to Study Tissue-Specific Sensitivities in Fanconi Anemia

RIG-I-Induced Type I IFNs Promote Regeneration of the Intestinal Stem Cell Compartment during Acute Tissue Damage

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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