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Journal Articles

Interrogation of Individual CLL Loss-of-Function Lesions By CRISPR In Vivo Editing Reveals Common and Unique Pathway Alterations

Blood (2019) 134 (Supplement_1): 684.

https://doi.org/10.1182/blood-2019-127673

Published: 2019

Journal Articles

Activated but Not Quiescent Hematopoietic Stem Cells Rely Readily on Glycolysis As Their Main Source of Energy

Tasleem Arif, PhD, Raymond Liang, PhD, Maio Lin, Msc, Svetlana Kalmikova, Msc, Artem Kasianov, PhD, Vijay Menon, PhD, Dmitri Papatsenko, PhD, Saghi Ghaffari, PhD MD

Blood (2019) 134 (Supplement_1): 271.

https://doi.org/10.1182/blood-2019-129099

Published: 2019

Journal Articles

Mitochondrial Oxphos As Survival Mechanism of Minimal Residual AML Cells after Induction Chemotherapy : Survival Benefit By Complex I Inhibition with Iacs-010759

Lina Han, PhD, Antonio Cavazos, Natalia Baran, PhDMD, Qi Zhang, PhD, Vinitha Mary Kuruvilla, MSc, Jason P Gay, MS, Ningping Feng, PhD, Venkata Lokesh Battula, PhD, Hagop M. Kantarjian, MD, Naval G. Daver, MD, Joseph R Marszalek, PhD, Michael Andreeff, MD PhD, Marina Y Konopleva, MD PhD

Blood (2019) 134 (Supplement_1): 5161.

https://doi.org/10.1182/blood-2019-124475

Published: 2019

Journal Articles

Inhibition of the MiR-185-PAK6-Mediated Survival and Metabolic Pathways Selectively Targets Drug-Resistant CML Stem/Progenitor Cells

Andrew Wu, BSc, Katharina Rothe, PhD, Min Chen, PhD, Hanyang Lin, PhD, Artem Babaian, PhD, Ryan Yen, BSc, Donna L. Forrest, MD, Xiaoyan Jiang, MD PhD

Blood (2019) 134 (Supplement_1): 4138.

https://doi.org/10.1182/blood-2019-127826

Published: 2019

Journal Articles

The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Complex and Supercomplex Formation and Is Necessary for AML Viability

Blood (2019) 134 (Supplement_1): 729.

https://doi.org/10.1182/blood-2019-122784

Published: 2019

Journal Articles

Oxidative Phosphorylation Regulated By PGC-1α Promotes Multiple Myeloma Progression

Yu Xiang, MD, Bin Fang, MD, Yilin Liu, MD, Siqi Yan, MD, Yicheng Zhang, Tao Guo, MD PhD

Blood (2019) 134 (Supplement_1): 5524.

https://doi.org/10.1182/blood-2019-127807

Published: 2019

Journal Articles

Unique Regulatory Pathways Dictate the Translational Program in Hematopoietic Stem and Progenitor Cells

Harold K. Elias, MD, Christina Spevak, PhD, Lavanya Kannan, PhD, Mohamed A.E. Ali, MD PhD, Gaelle H Martin, PhD, Shanmugapriya Selvaraj, MS, William S Eng, Guangjie Zhao, BS, Amanda Ernlund, PhD, Vinagolu Rajasekhar, PhD, Carolien M Woolthuis, MD PhD, Robert J Schneider, PhD, Christopher Y. Park, MD PhD

Blood (2019) 134 (Supplement_1): 1180.

https://doi.org/10.1182/blood-2019-131333

Published: 2019

Journal Articles

Electron Transport Chain Complex II Sustains High Mitochondrial Membrane Potential in Hematopoietic Stem and Progenitor Cells

Claudia Morganti, PhD, Massimo Bonora, PhD, Kyoko Ito, Keisuke Ito, MD PhD

Blood (2019) 134 (Supplement_1): 1188.

https://doi.org/10.1182/blood-2019-125891

Published: 2019

Journal Articles

SIRT1 Mediates Enhanced Mitochondrial Oxidative Phosphorylation in Chronic Myelogenous Leukemia Stem Cells

Ajay Abraham, PhD, Shaowei Qiu, MD, Balu K Chacko, PhD, Hui Li, BS, Andrew J Paterson, PhD, Jianbo He, MD, Puneet Agarwal, PhD, Mansi Shah, PhD, Robert S. Welner, PhD, Victor M Darley-Usmar, PhD, Ravi Bhatia, MD

Blood (2018) 132 (Supplement 1): 932.

https://doi.org/10.1182/blood-2018-99-115709

Published: 2018

Journal Articles

SIRT3 Sumoylation Contributes to Chemoresistance in AML

Jiao MA, PhD, Bin Liu, MSc, Dan Yu, BSc, Wayne Tam, MD PhD, Jianmin Yang, PhD, Jinke Cheng, PhD

Blood (2018) 132 (Supplement 1): 3929.

https://doi.org/10.1182/blood-2018-99-110898

Published: 2018

Journal Articles

Synergistic Pre-Clinical Activity of Targeted Inhibition of KDM1A and BET Proteins Against Human AML Blast Progenitor Cells

Warren Fiskus, BSc, PhD, Christopher Peter Mill, PhD BA, Raffaella Soldi, Roulan Han, Dyana T. Saenz, PhD, Agnieszka J Nowak, Baohua Sun, MD PhD, David N Saenz, Courtney D. DiNardo, MD MSc, Gautam Borthakur, MD, Tapan M. Kadia, MD, Wendy Jin, Thurika Ganesh, Vaishnavi Rao, Joseph David Khoury, MD, Sunil Sharma, MD, Kapil N. Bhalla, MD

Blood (2018) 132 (Supplement 1): 3930.

https://doi.org/10.1182/blood-2018-99-114198

Published: 2018

Journal Articles

Adaptation to Metabolic Stress By Mondoα in Common B-Cell Acute Lymphoblastic Leukemia

Alexandra Sipol, Andreas Petry, Erik Hameister, Agnes Görlach, Jürgen Ruland, Stefan Burdach, Poul Sorensen

Blood (2018) 132 (Supplement 1): 3888.

https://doi.org/10.1182/blood-2018-99-114014

Published: 2018

Journal Articles

Mitochondrial Complex I Inhibitor Iacs-010759 Reverses the NOTCH1-Driven Metabolic Reprogramming in T-ALL Via Blockade of Oxidative Phosphorylation: Synergy with Chemotherapy and Glutaminase Inhibition

Blood (2018) 132 (Supplement 1): 4020.

https://doi.org/10.1182/blood-2018-99-117310

Published: 2018

Journal Articles

The NAD+ Salvage Pathway Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance and Asymmetric Division

Blood (2018) 132 (Supplement 1): 641.

https://doi.org/10.1182/blood-2018-99-117388

Published: 2018

Journal Articles

Age-Dependent Decrease in Requirement for Glycolysis in Hematopoietic Stem Cells

Watanuki Shintaro, Hiroshi Kobayashi, MD PhD, Daiki Karigane, MDPhD, Yukako Ootomo, Ayumi Okinaga, Shinichiro Okamoto, MD PhD, Keiyo Takubo, MD PhD

Blood (2018) 132 (Supplement 1): 328.

https://doi.org/10.1182/blood-2018-99-111616

Published: 2018

Journal Articles

Characteristic Amino Acid and Energy Metabolism in AML Stem Cells As Revealed By Quantitative Multiplex Proteomics

Simon Raffel, MD, Jenny Hansson, Mattia Falcone, Christoph Lutz, Oliver Bischel, MD, Anthony D Ho, Jeroen Krijgsveld, Andreas Trumpp, Prof, PhD

Blood (2018) 132 (Supplement 1): 2780.

https://doi.org/10.1182/blood-2018-99-117046

Published: 2018

Journal Articles

CD166 Engagement Augments Mouse and Human Hematopoietic Stem and Progenitor Function Via Activation of Stem Cell-Associated and Cell Cycle Pathways

Joydeep Ghosh, PhD, Jing Zhang, PhD, Chi Zhang, PhD, Xinxin Huang, PhD, Safa F. Mohamad, MS, Maegan L. Capitano, PhD, Andrea M. Gunawan, Scott Cooper, MS, Bin Guo, PhD, Qingchun Cai, PhD, Hal E. Broxmeyer, PhD, Edward F. Srour, PhD

Blood (2018) 132 (Supplement 1): 1282.

https://doi.org/10.1182/blood-2018-99-119251

Published: 2018

Journal Articles

Enhanced phosphocholine metabolism is essential for terminal erythropoiesis

Nai-Jia Huang, Ying-Cing Lin, Chung-Yueh Lin, Novalia Pishesha, Caroline A. Lewis, Elizaveta Freinkman, Colin Farquharson, José Luis Millán, Harvey Lodish

Blood (2018) 131 (26): 2955–2966.

https://doi.org/10.1182/blood-2018-03-838516

Published: 2018

Includes: Supplemental data

Journal Articles

Control of Hematopoietic Stem Cell Function through Epigenetic Regulation of Energy Metabolism and Genome Integrity

Zhenhua Yang, PhD, Hao Jiang

Blood (2017) 130 (Supplement 1): 772.

https://doi.org/10.1182/blood.V130.Suppl_1.772.772

Published: 2017

Journal Articles

Glia Maturation Factor-Gamma Modulates M2 Activation of Macrophage Via Suppression of Mitochondria Function

Wulin Aerbajinai, MD PhD, Jie Liu, Chutima Kumkhaek, Jianqiong Zhu, Kyung Chin, Griffin Rodgers, MD

Blood (2017) 130 (Supplement 1): 998.

https://doi.org/10.1182/blood.V130.Suppl_1.998.998

Published: 2017

NARROW

Interrogation of Individual CLL Loss-of-Function Lesions By CRISPR In Vivo Editing Reveals Common and Unique Pathway Alterations

Activated but Not Quiescent Hematopoietic Stem Cells Rely Readily on Glycolysis As Their Main Source of Energy

Mitochondrial Oxphos As Survival Mechanism of Minimal Residual AML Cells after Induction Chemotherapy : Survival Benefit By Complex I Inhibition with Iacs-010759

Inhibition of the MiR-185-PAK6-Mediated Survival and Metabolic Pathways Selectively Targets Drug-Resistant CML Stem/Progenitor Cells

The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Complex and Supercomplex Formation and Is Necessary for AML Viability

Oxidative Phosphorylation Regulated By PGC-1α Promotes Multiple Myeloma Progression

Unique Regulatory Pathways Dictate the Translational Program in Hematopoietic Stem and Progenitor Cells

Electron Transport Chain Complex II Sustains High Mitochondrial Membrane Potential in Hematopoietic Stem and Progenitor Cells

SIRT1 Mediates Enhanced Mitochondrial Oxidative Phosphorylation in Chronic Myelogenous Leukemia Stem Cells

SIRT3 Sumoylation Contributes to Chemoresistance in AML

Synergistic Pre-Clinical Activity of Targeted Inhibition of KDM1A and BET Proteins Against Human AML Blast Progenitor Cells

Adaptation to Metabolic Stress By Mondoα in Common B-Cell Acute Lymphoblastic Leukemia

Mitochondrial Complex I Inhibitor Iacs-010759 Reverses the NOTCH1-Driven Metabolic Reprogramming in T-ALL Via Blockade of Oxidative Phosphorylation: Synergy with Chemotherapy and Glutaminase Inhibition

The NAD+ Salvage Pathway Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance and Asymmetric Division

Age-Dependent Decrease in Requirement for Glycolysis in Hematopoietic Stem Cells

Characteristic Amino Acid and Energy Metabolism in AML Stem Cells As Revealed By Quantitative Multiplex Proteomics

CD166 Engagement Augments Mouse and Human Hematopoietic Stem and Progenitor Function Via Activation of Stem Cell-Associated and Cell Cycle Pathways

Enhanced phosphocholine metabolism is essential for terminal erythropoiesis

Control of Hematopoietic Stem Cell Function through Epigenetic Regulation of Energy Metabolism and Genome Integrity

Glia Maturation Factor-Gamma Modulates M2 Activation of Macrophage Via Suppression of Mitochondria Function

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American Society of Hematology

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ASH Publications

American Society of Hematology

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