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Journal Articles

MGP Interacts with BMP-4 and BMP-2 and Supports Normal and Malignant Hematopoietic Stem/Progenitor Cells

Aya Yokoi, Kana Kuronuma, Tomoya Fukuoka, Chie Goto, Miki Matsuo, Eri Adachi, Naoko Okada, Hikaru Tsutsumi, Mirano Kajitani, Natsumi Hasegawa, Shigetaka Asano, MD DSc, Mitsuhiro Ito, MDPhD

Blood (2018) 132 (Supplement 1): 2582.

https://doi.org/10.1182/blood-2018-99-110138

Published: 2018

Journal Articles

Small-Molecule Inhibition of PRMT5 Induces Translational Stress and p53 in JAK2V617F Mutant Myeloproliferative Neoplasms

Stefan Sonderegger, PhD MSc, Loretta Cerruti, BSc, Cedric Tremblay, PhD, Emma Toulmin, PhD, Jesslyn Saw, BSc, Tom Nebl, PhD, Katherine M Hannan, PhD, Steven W. Lane, MD PhD, Hendrik Falk, PhD, Ashwin Unnikrishnan, PhD, Paul Stupple, PhD, Ian Street, PhD, Stephen Jane, MDPhD, Rachel Altura, PhD, Benjamin Nicholson, PhD, David J. Curtis, MBBS,PhD

Blood (2018) 132 (Supplement 1): 53.

https://doi.org/10.1182/blood-2018-99-118406

Published: 2018

Journal Articles

The Expression of EIF2S3 in Acute Myeloid Leukemia and Its Prognostic Significance

Jielun Lu, Lihua Xu, Xiaodan Luo, MD, Shuyi Chen, Yawei Zou, Huo Tan, MD

Blood (2018) 132 (Supplement 1): 5139.

https://doi.org/10.1182/blood-2018-99-112948

Published: 2018

Journal Articles

Optimizing Mechanisms for Induction of Immunogenic Cell Death to Improve Patient Outcome in Multiple Myeloma

Annamaria Gulla, MD, Eugenio Morelli, MD, Teru Hideshima, MD PhD, Mehmet Kemal Samur, PhD, Giada Bianchi, MD, Mariateresa Fulciniti, PhD, Nikhil Munshi, MD, Kenneth C. Anderson, MD

Blood (2018) 132 (Supplement 1): 1932.

https://doi.org/10.1182/blood-2018-99-116951

Published: 2018

Journal Articles

The Hypomorphic Gata1 low Mutation Induces Fibrosis in Multiple Organs

Maria Zingariello, Laura Sancillo, Fabrizio Martelli, Paola Verachi, Claudio Bardelli, Mauro Valeri, Yujin Hoshida, Fiorella Ciaffoni, Manuela Marra, Rosa Alba Rana, Anna Rita Migliaccio, PhD

Blood (2018) 132 (Supplement 1): 3059.

https://doi.org/10.1182/blood-2018-99-110927

Published: 2018

Journal Articles

Silencing Oncogene Translation Using Pateamine a Analogues As a Novel Therapeutic Strategy for c-Myc Driven Lymphoma

Yu Ri Kim, MD, Ipsita Pal, PhD, Mark R Lipstein, PhD, Mingzhao Zhu, Hull Kenneth, Daniel Romo, Owen A. O'Connor, MD, PhD, Changchun Deng, MD PhD

Blood (2017) 130 (Supplement 1): 4111.

https://doi.org/10.1182/blood.V130.Suppl_1.4111.4111

Published: 2017

Journal Articles

Umbralisib/TGR-1202 As a Novel Dual PI3K/CK1 Inhibitor Has a Unique Therapeutic Role in Silencing Oncogenes in Aggressive Lymphomas

Ipsita Pal, PhD, Yu Ri Kim, MD, Luigi Scotto, PhD, Mark R Lipstein, PhD, Abdullah Mahmood Ali, PhD, Siddhartha Mukherjee, MD PhD, Susan E. Bates, MDPhD, Owen A. O'Connor, MD, PhD, Changchun Deng, MD PhD

Blood (2017) 130 (Supplement 1): 2809.

https://doi.org/10.1182/blood.V130.Suppl_1.2809.2809

Published: 2017

Journal Articles

Direct-Acting Small Molecule Activators of PP2A (SMAPs) in Myeloid Malignancies: Understanding Mechanisms of Cytotoxicity to Inform Rational Combinatorial Therapeutic Strategies

Christopher B Ryder, Goutham Narla, MD PhD

Blood (2017) 130 (Supplement 1): 2517.

https://doi.org/10.1182/blood.V130.Suppl_1.2517.2517

Published: 2017

Journal Articles

Preclinical Evaluation of eFT226, a Novel, Potent and Selective eIF4A Inhibitor with Anti-Tumor Activity in B-Cell Malignancies

Blood (2017) 130 (Supplement 1): 1530.

https://doi.org/10.1182/blood.V130.Suppl_1.1530.1530

Published: 2017

Journal Articles

Domain-Focused CRISPR-Cas9 Screen Identifies Hri Kinase As a Regulator of Fetal Hemoglobin in Adult Human Erythroid Cells

Jeremy D. Grevet, Nicole Hamagami, Xianjiang Lan, PhD, Laavanya Sankaranarayanan, MS, Saurabh Bhardwaj, PhD, Carolyne Face, David Posocco, Osheiza Abdulmalik, DVM, Cheryl A. Keller, PhD, Belinda Giardine, Simone Sidoli, PhD, Ben Garcia, PhD, Stella T Chou, MD, Ross C Hardison, PhD, Chris Vakoc, MD PhD, Junwei Shi, PhD, Gerd A. Blobel, MD PhD

Blood (2017) 130 (Supplement 1): 536.

https://doi.org/10.1182/blood.V130.Suppl_1.536.536

Published: 2017

Journal Articles

Widespread and dynamic translational control of red blood cell development

Juan R. Alvarez-Dominguez, Xu Zhang, Wenqian Hu

Blood (2017) 129 (5): 619–629.

https://doi.org/10.1182/blood-2016-09-741835

Published: 2017

Includes: Supplemental data

Journal Articles

Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies

Changchun Deng, Mark R. Lipstein, Luigi Scotto, Xavier O. Jirau Serrano, Michael A. Mangone, Shirong Li, Jeremie Vendome, Yun Hao, Xiaoming Xu, Shi-Xian Deng, Ronald B. Realubit, Nicholas P. Tatonetti, Charles Karan, Suzanne Lentzsch, David A. Fruman, Barry Honig, Donald W. Landry, Owen A. O’Connor

Blood (2017) 129 (1): 88–99.

https://doi.org/10.1182/blood-2016-08-731240

Published: 2017

Includes: Supplemental data

Journal Articles

Widespread and Dynamic Translational Control of Red Blood Cell Development

Wenqian Hu, PhD, Xu Zhang, Juan Alvarez-Dominguez

Blood (2016) 128 (22): 1260.

https://doi.org/10.1182/blood.V128.22.1260.1260

Published: 2016

Journal Articles

Silencing c-Myc Translation As a Therapeutic Strategy through Targeting PI3K Delta and CK1 Epsilon in Hematological Malignancies

Changchun Deng, MD PhD, Mark Lipstein, Luigi Scotto, PhD, Xavier O Jirau Serrano, B.S., Michael Mangone, PhD, Shirong Li, PhD, Jeremie Vendome, PhD, Yun Hao, Xiaoming Xu, Xiaoping Liu, MD PhD, Ipsita Pal, PhD, Shi-Xian Deng, PhD, Nicholas P. Tatonetti, PhD, Suzanne Lentzsch, MD PhD, Barry Honig, PhD, Donald Landry, MD PhD, Owen A. O'Connor, MD PhD

Blood (2016) 128 (22): 291.

https://doi.org/10.1182/blood.V128.22.291.291

Published: 2016

Journal Articles

Ribavirin, an eIF4E Inhibitor, As a Potential Anti-Lymphoma Therapeutic - Preclinical and Early Clinical Data

Sarah C. Rutherford, MD, Eric Stewart, MD, Tharu M Fernando, MS, Biljana Culjkovic-Kraljacic, Katherine L. B. Borden, Koen van Besien, MD, Peter Martin, MD, Richard R Furman, MD, John P. Leonard, MD, Leandro Cerchietti, MD

Blood (2016) 128 (22): 3045.

https://doi.org/10.1182/blood.V128.22.3045.3045

Published: 2016

Journal Articles

Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo

Ewa M. Kosciuczuk, Diana Saleiro, Barbara Kroczynska, Elspeth M. Beauchamp, Frank Eckerdt, Gavin T. Blyth, Sameem M. Abedin, Francis J. Giles, Jessica K. Altman, Leonidas C. Platanias

Blood (2016) 128 (3): 410–414.

https://doi.org/10.1182/blood-2016-02-698704

Published: 2016

Includes: Supplemental data

Journal Articles

BCR engagement in CLL: when translation goes wrong

Jerome Paggetti, Etienne Moussay

Blood (2016) 127 (4): 378–380.

https://doi.org/10.1182/blood-2015-11-678623

Published: 2016

Journal Articles

Comparative Proteomic Profiling of Refractory/Relapsed Multiple Myeloma Patient Plasma Cells Reveals Biomarkers and Pathways Involved in Bortezomib-Based-Therapy Resistance

Dominik Dytfeld, MD PhD, Magdalena Luczak, PhD, Anna Przybylowicz-Chalecka, Msc, Blazej Ratajczak, MSc, Adam Nowicki, MD, Joanna Czerwinska-Rybak, MSc, Monika Joks, MD PhD, Tomasz Szczepaniak, MD PhD, Bochenek Maciej, Andrzej Jakubowiak, MD PhD, Mieczyslaw Komarnicki, MD PhD

Blood (2015) 126 (23): 2986.

https://doi.org/10.1182/blood.V126.23.2986.2986

Published: 2015

Journal Articles

S6K1 Regulates Self-Renewal of Leukemia Initiating Cells and Normal Hematopoietic Stem Cells

Joydeep Ghosh, MSc, Anindya Chatterjee, MS,PhD, Baskar Ramdas, PhD, Michihiro Kobayashi, MD PhD, Peilin Ma, MD PhD, Yan Liu, PhD, David Plas, PhD, Reuben Kapur, PhD

Blood (2015) 126 (23): 442.

https://doi.org/10.1182/blood.V126.23.442.442

Published: 2015

Journal Articles

The T-Cell/CLL/Macrophage Triad Shapes a Supportive Tumor Microenvironment in CLL

Martijn H.A. van Attekum, MD, Sanne Terpstra, Emilie Reinen, Marieke Von Lindern, PhD, Erik Slinger, PhD, Eldering Eric, PhD, Arnon P. Kater, MD PhD

Blood (2015) 126 (23): 1715.

https://doi.org/10.1182/blood.V126.23.1715.1715

Published: 2015

NARROW

MGP Interacts with BMP-4 and BMP-2 and Supports Normal and Malignant Hematopoietic Stem/Progenitor Cells

Small-Molecule Inhibition of PRMT5 Induces Translational Stress and p53 in JAK2V617F Mutant Myeloproliferative Neoplasms

The Expression of EIF2S3 in Acute Myeloid Leukemia and Its Prognostic Significance

Optimizing Mechanisms for Induction of Immunogenic Cell Death to Improve Patient Outcome in Multiple Myeloma

The Hypomorphic Gata1 low Mutation Induces Fibrosis in Multiple Organs

Silencing Oncogene Translation Using Pateamine a Analogues As a Novel Therapeutic Strategy for c-Myc Driven Lymphoma

Umbralisib/TGR-1202 As a Novel Dual PI3K/CK1 Inhibitor Has a Unique Therapeutic Role in Silencing Oncogenes in Aggressive Lymphomas

Direct-Acting Small Molecule Activators of PP2A (SMAPs) in Myeloid Malignancies: Understanding Mechanisms of Cytotoxicity to Inform Rational Combinatorial Therapeutic Strategies

Preclinical Evaluation of eFT226, a Novel, Potent and Selective eIF4A Inhibitor with Anti-Tumor Activity in B-Cell Malignancies

Domain-Focused CRISPR-Cas9 Screen Identifies Hri Kinase As a Regulator of Fetal Hemoglobin in Adult Human Erythroid Cells

Widespread and dynamic translational control of red blood cell development

Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies

Widespread and Dynamic Translational Control of Red Blood Cell Development

Silencing c-Myc Translation As a Therapeutic Strategy through Targeting PI3K Delta and CK1 Epsilon in Hematological Malignancies

Ribavirin, an eIF4E Inhibitor, As a Potential Anti-Lymphoma Therapeutic - Preclinical and Early Clinical Data

Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo

BCR engagement in CLL: when translation goes wrong

Comparative Proteomic Profiling of Refractory/Relapsed Multiple Myeloma Patient Plasma Cells Reveals Biomarkers and Pathways Involved in Bortezomib-Based-Therapy Resistance

S6K1 Regulates Self-Renewal of Leukemia Initiating Cells and Normal Hematopoietic Stem Cells

The T-Cell/CLL/Macrophage Triad Shapes a Supportive Tumor Microenvironment in CLL

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American Society of Hematology

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ASH Publications

American Society of Hematology

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