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Journal Articles

Sickle Cell Hemoglobin Impairs Lysosomal Processing in Macrophages Leading to Inflammasome Activation and Inflammation

Marina Jerebtsova, PhD, Xiaomei Niu, MD, Sharmin Diaz, NP, Namita Kumari, PhD, Sergei Nekhai, PhD

Blood (2019) 134 (Supplement_1): 979.

https://doi.org/10.1182/blood-2019-130741

Published: 2019

Journal Articles

Downregulation of Cytoskeletal Protein Kazrin in Lung Endothelial Cells of Preclinical Sickle Cell Disease Mouse Model - Essential Role of Endothelial Barrier Function

Umapathy N Siddaramappa, PhD, Niren Patel, MBBS, Betty S. Pace, MD, Abdullah Kutlar, MD

Blood (2019) 134 (Supplement_1): 2258.

https://doi.org/10.1182/blood-2019-130924

Published: 2019

Journal Articles

Harnessing a Novel Dyrk1a-Ablim2-MKL1 Regulatory Module in Megakaryocyte Morphogenesis to Enable Scalable Platelet "Pharming"

Kamaleldin E Elagib, PhDMBBS, Ashton Brock, PhD, Goar Mosoyan, Cara Clementelli, Lorrie L Delehanty, BS, Alexandra Pacheco-Benichou, Corinne Fruit, Thierry Besson, PhD, Stephen Morris, MD, Koji Eto, MD, Camelia Iancu-Rubin, PhD, Adam N Goldfarb, MD

Blood (2019) 134 (Supplement_1): 3250.

https://doi.org/10.1182/blood-2019-129049

Published: 2019

Journal Articles

Optimized Beta-Globin Expression and Enucleation from Induced Red Blood Cells for In Vitro Modeling of Sickle Cell Disease

Tolulope O Rosanwo, BA, Melissa Kinney, PhD, Martha A Clark, PhD, Linda T Vo, PhD, R. Grant Rowe, MD PhD, Natasha M. Archer, MD, Matthew M Heeney, MD, Thorsten Schlaeger, PhD, Daniel E. Bauer, MD PhD, Mark D. Fleming, MD DPhil, Manoj T Duraisingh, PhD, Stuart H. Orkin, MD, Carlo Brugnara, MD, Trista North, PhD, George Q. Daley, MD PhD

Blood (2018) 132 (Supplement 1): 2359.

https://doi.org/10.1182/blood-2018-99-114136

Published: 2018

Journal Articles

Circulating Exosomes Isolated during Acute Chest Syndrome Disrupt Endothelial Integrity

Gabrielle Lapping-Carr, MD, Joanna Gemel, PhD, Yifan Mao, Gianna Sparks, Margaret Harrington, Rebecca Sturey, MS, Shelby Gruntorad, MS, Wendy S Darlington, MD MAPP, Radhika Peddinti, MD, Eric C. Beyer, MD PhD

Blood (2018) 132 (Supplement 1): 2363.

https://doi.org/10.1182/blood-2018-99-111907

Published: 2018

Journal Articles

Activin A, a Potential Key Factor of the Malignant Bone Marrow Niche, Enhances B-Cell Precursor-Acute Lymphoblastic Leukemic Cell Migratory and Invasive Properties

Erica Dander, PhD, Federica Portale, PhD, Daniela Silvestri, Giulia Cricrì, Silvia Bresolin, PhD, Stefania Gaspari, Barbara Russo, Monica Lupi, Paolo Ubezio, Geertruy te Kronnie, Maria Grazia Valsecchi, PhD, Franco Locatelli, Carmelo Rizzari, MD, Andrea Biondi, MD, Giovanna D'Amico, BSc, PhD MSc

Blood (2018) 132 (Supplement 1): 1296.

https://doi.org/10.1182/blood-2018-99-116668

Published: 2018

Journal Articles

Cofilin-1 Activation in Stored Platelets

Swapan Kumar Dasgupta, PhD, Perumal Thiagarajan, MD

Blood (2018) 132 (Supplement 1): 1256.

https://doi.org/10.1182/blood-2018-99-119159

Published: 2018

Journal Articles

The “Feedback” Regulation of Thrombopoiesis: The Role of Serotonin on Proplatelet Formation and TPO Production

Mo Yang, MD PhD, En-yu Liang, Jieyu Ye, MD PhD, Hui-ling Wei, M.B, Beng H Chong, MBBS, PhD, Chunfu Li, MD

Blood (2017) 130 (Supplement 1): 4949.

https://doi.org/10.1182/blood.V130.Suppl_1.4949.4949

Published: 2017

Journal Articles

Thrombin Induces Protease Activated Receptor (PAR)-3/-4 Interaction in Human Podocytes

Sharma Ruchika, MD, Amanda P Waller, PhD, Shipra Agrawal, PhD, Berend H Isermann, MD, William E Smoyer, MD, Marvin T Nieman, PhD, Bryce A. Kerlin, MD

Blood (2015) 126 (23): 3488.

https://doi.org/10.1182/blood.V126.23.3488.3488

Published: 2015

Journal Articles

Establishment of Human Adipose Tissue-Derived Stromal Cell Lines: A Culture System to Manufacture Megakaryocytes Releasing Functional Platelets

Keiichi Tozawa, MD, Yukako Ono-Uruga, MD PhD, Noriko Takizawa, Tadashi Horiuchi, Shin-ichiro Okamoto, MD PhD, Mitsuru Murata, MD PhD, Yasuo Ikeda, MD PhD, Yumiko Matsubara, PhD

Blood (2015) 126 (23): 656.

https://doi.org/10.1182/blood.V126.23.656.656

Published: 2015

Journal Articles

Bone Marrow Microenvironment Regulates Alternative Splicing Events in Myeloma Cells through Downregulation of RNA Binding Protein Fox2

Blood (2014) 124 (21): 4714.

https://doi.org/10.1182/blood.V124.21.4714.4714

Published: 2014

Journal Articles

A Crucial Role for Caspase 1 in Thrombo-Inflammatory Microparticle Release

Andrea S Rothmeier, PhD, Patrizia Marchese, PhD, Christian Furlan-Freguia, PhD, Brian G. Petrich, PhD, Mark H. Ginsberg, MD, Zaverio M Ruggeri, MD, Wolfram Ruf, MD

Blood (2014) 124 (21): 2806.

https://doi.org/10.1182/blood.V124.21.2806.2806

Published: 2014

Journal Articles

Thrombin Induces Apoptosis in Human and Rat Podocytes in a Protease Activated Receptor (PAR)-Dependent Manner

Ruchika Sharma, MD, Amanda P Waller, PhD, Adam Guess, Shipra Agrawal, PhD, Berend Isermann, William E. Smoyer, MD, Marvin T. Nieman, PhD, Bryce A. Kerlin, MD

Blood (2014) 124 (21): 2808.

https://doi.org/10.1182/blood.V124.21.2808.2808

Published: 2014

Journal Articles

Cofilin-1 – Induced Actin Reorganization and Phosphatidylserine Exposure in Platelets

Swapan Dasgupta, PhD, Anhquyen Le, Sandra Haudek, PhD, Mark Entman, MD, Perumal Thiagarajan, MD

Blood (2014) 124 (21): 4153.

https://doi.org/10.1182/blood.V124.21.4153.4153

Published: 2014

Journal Articles

Distinct Localization of Coagulation Factor VIII, Von Willebrand Factor and Factor VIIIa-Mimetic Bispecific Antibody Contributing to Thrombus Formation Under Whole Blood Flow Conditions

Yasuaki Shida, MD PhD, Keiji Nogami, MD PhD, Hiroaki Minami, MD, Hiroaki Yaoi, MD, Tomoko Matsumoto, PhD, Takehisa Kitazawa, DVM, Kunihiro Hattori, PhD, Midori Shima, MD PhD

Blood (2014) 124 (21): 1483.

https://doi.org/10.1182/blood.V124.21.1483.1483

Published: 2014

Journal Articles

“Self-Deposition” of Matrix Proteins from Platelet α-Granules Enable Extended Adhesion and Spreading on Micron/Submicron-Scale Fibrinogen and Collagen Substrates.

Yumiko Sakurai, MSc, Jennifer L Fitch-Tewfik, PhD, Yongzhi Qiu, PhD, David R Myers, PhD, Byungwook Ahn, PhD, Robert Flaumenhaft, MD/ PhD, Wilbur A Lam, MD PhD

Blood (2014) 124 (21): 2764.

https://doi.org/10.1182/blood.V124.21.2764.2764

Published: 2014

Journal Articles

Disruption Of CD9 Expression Affects Adhesion, Migration and Engraftment Of Pre-B Lymphocytes

Marie-Pierre Arnaud, Audrey Vallée, PhD, Guillaume Robert, Anne-Gaelle Rio, Elisabetta Dondi, PhD, Jacinthe Bonneau, MD, Christine LE ROY, PhD, Nadine Varin-Blank, PhD, Marie-Dominique Galibert, PhD, PharmD, Marie-Bérengère Troadec, PhD, Virginie Gandemer, MD, PhD

Blood (2013) 122 (21): 1222.

https://doi.org/10.1182/blood.V122.21.1222.1222

Published: 2013

Journal Articles

Targeting The BRAF-MEK-ERK Pathway In Hairy Cell Leukemia

Valentina Pettirossi, Alessia Santi, Guido Russo, Alessandra Pucciarini, Barbara Bigerna, Elisabetta Fortini, Elisa Imperi, Roberta Mannucci, Ildo Nicoletti, Maria Paola Martelli, Enrico Tiacci, Brunangelo Falini

Blood (2013) 122 (21): 3064.

https://doi.org/10.1182/blood.V122.21.3064.3064

Published: 2013

Journal Articles

Bone Marrow Microenvironment Affects The Pathogenesis Of Multiple Myeloma Through Downregulation Of Alternative Splicing Factor Fox2 In Myeloma Cells

Weihua Song, MD, Chaolin Zhang, PhD, Yiguo Hu, PhD, Maria Gkotzamanidou, MD, Parantu Shah, PhD, Weisong Shan, MD PhD, Guang Yang, PhD, Samir B. Amin, MBBS, Yu-Tzu Tai, PhD, Yi Li, PhD, Adam Sperling, MD, PhD, Naim Rashid, PhD, Florence Magrangeas, PhD, Stephane Minvielle, PhD, Hervé Avet-Loiseau, MD, PhD, Kenneth C. Anderson, MD, Cheng Li, PhD, Nikhil C. Munshi, MD

Blood (2013) 122 (21): 3085.

https://doi.org/10.1182/blood.V122.21.3085.3085

Published: 2013

Journal Articles

Reversible Association of 14-3-3 with Platelet Glycoprotein Ibα Regulates the Ability of Cells to Adhere, Roll and Spread On VWF

Adam D. Munday, PhD, Jose A. Lopez, MD

Blood (2012) 120 (21): 1061.

https://doi.org/10.1182/blood.V120.21.1061.1061

Published: 2012

NARROW

Sickle Cell Hemoglobin Impairs Lysosomal Processing in Macrophages Leading to Inflammasome Activation and Inflammation

Downregulation of Cytoskeletal Protein Kazrin in Lung Endothelial Cells of Preclinical Sickle Cell Disease Mouse Model - Essential Role of Endothelial Barrier Function

Harnessing a Novel Dyrk1a-Ablim2-MKL1 Regulatory Module in Megakaryocyte Morphogenesis to Enable Scalable Platelet "Pharming"

Optimized Beta-Globin Expression and Enucleation from Induced Red Blood Cells for In Vitro Modeling of Sickle Cell Disease

Circulating Exosomes Isolated during Acute Chest Syndrome Disrupt Endothelial Integrity

Activin A, a Potential Key Factor of the Malignant Bone Marrow Niche, Enhances B-Cell Precursor-Acute Lymphoblastic Leukemic Cell Migratory and Invasive Properties

Cofilin-1 Activation in Stored Platelets

The “Feedback” Regulation of Thrombopoiesis: The Role of Serotonin on Proplatelet Formation and TPO Production

Thrombin Induces Protease Activated Receptor (PAR)-3/-4 Interaction in Human Podocytes

Establishment of Human Adipose Tissue-Derived Stromal Cell Lines: A Culture System to Manufacture Megakaryocytes Releasing Functional Platelets

Bone Marrow Microenvironment Regulates Alternative Splicing Events in Myeloma Cells through Downregulation of RNA Binding Protein Fox2

A Crucial Role for Caspase 1 in Thrombo-Inflammatory Microparticle Release

Thrombin Induces Apoptosis in Human and Rat Podocytes in a Protease Activated Receptor (PAR)-Dependent Manner

Cofilin-1 – Induced Actin Reorganization and Phosphatidylserine Exposure in Platelets

Distinct Localization of Coagulation Factor VIII, Von Willebrand Factor and Factor VIIIa-Mimetic Bispecific Antibody Contributing to Thrombus Formation Under Whole Blood Flow Conditions

“Self-Deposition” of Matrix Proteins from Platelet α-Granules Enable Extended Adhesion and Spreading on Micron/Submicron-Scale Fibrinogen and Collagen Substrates.

Disruption Of CD9 Expression Affects Adhesion, Migration and Engraftment Of Pre-B Lymphocytes

Targeting The BRAF-MEK-ERK Pathway In Hairy Cell Leukemia

Bone Marrow Microenvironment Affects The Pathogenesis Of Multiple Myeloma Through Downregulation Of Alternative Splicing Factor Fox2 In Myeloma Cells

Reversible Association of 14-3-3 with Platelet Glycoprotein Ibα Regulates the Ability of Cells to Adhere, Roll and Spread On VWF

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American Society of Hematology

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ASH Publications

American Society of Hematology

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