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Journal Articles

Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells

Brief Report
Pia Sommerkamp, Mari Carmen Romero-Mulero, Andreas Narr, Luisa Ladel, Lucie Hustin, Katharina Schönberger, Simon Renders, Sandro Altamura, Petra Zeisberger, Karin Jäcklein, Daniel Klimmeck, Alejo Rodriguez-Fraticelli, Fernando D. Camargo, Leïla Perié, Andreas Trumpp, Nina Cabezas-Wallscheid
Journal: Blood
Blood (2021) 137 (23): 3218–3224.
https://doi.org/10.1182/blood.2020007876
Published: 2021
Includes: Supplemental data
Journal Articles

CD86-based analysis enables observation of bona fide hematopoietic responses

Masashi Kanayama, Yuta Izumi, Yasuharu Yamauchi, Shoko Kuroda, Takaei Shin, Shun Ishikawa, Taku Sato, Mihoko Kajita, Toshiaki Ohteki
Journal: Blood
Blood (2020) 136 (10): 1144–1154.
https://doi.org/10.1182/blood.2020004923
Published: 2020
Includes: Supplemental data
Journal Articles

Talazoparib Treatment Preferentially Depletes Cohesin-Mutant Clones in New In Vivo M odels of Cohesin-Mutant Myeloid Diseases

Mounica Vallurupalli, MD, Rebecca Gorelov, BS, Jacqueline S Garcia, MD, Elizabeth A Morgan, MD, Benjamin Ebert, MD, Zuzana Tothova, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 560.
https://doi.org/10.1182/blood-2019-130308
Published: 2019
Journal Articles

Non-Coding HOX Fusions in Pediatric Non-Down Syndrome Acute Megakaryoblastic Leukemia

Fabienne R.S. Adriaanse, MSc, Sadie M. Sakurada, B.A., Shondra M. Pruett-Miller, PhD, Ronald W. Stam, PhD, Michel C Zwaan, MD PhD, Tanja A. Gruber, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 533.
https://doi.org/10.1182/blood-2019-127014
Published: 2019
Journal Articles

Single-Cell Characterization of the Multiple Myeloma (MM) Immune Microenvironment Identifies CD27-Negative T Cells As Potential Source of Tumor-Reactive Lymphocytes

Cirino Botta, MD, Cristina Pérez Ruiz, Ibai Goicoechea, PhD, Noemi Puig, MD PhD, María Teresa Cedena, Lourdes Cordon, Aintzane Zabaleta, PhD, Leire Burgos, Catarina Maia, Sara Rodríguez, PhD, Idoia Rodriguez, Sarai Sarvide, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Erika Lorenzo-Vivas, PhD, Laura Rosinol Dachs, Albert Oriol, MD, María Jesús Blanchard, Rafael Rios, MD PhD, Anna Sureda, MD PhD, Rafael Martínez, Jesús Martín, Joan Bargay, MD PhD, Javier De La Rubia, Marco Rossi, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD, Massimo Gentile, Juana Merino, Felipe Prosper, MD PhD, Alberto Orfao, MD PhD, Maria-Victoria Mateos, Juan-José Lahuerta, MD PhD, Joan Bladé, MD PhD, Jesús San-Miguel, Bruno Paiva, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 506.
https://doi.org/10.1182/blood-2019-123974
Published: 2019
Journal Articles

TGF-β Signaling Contributes to Myelofibrosis and Clonal Dominance of Myeloproliferative Neoplasms

Juo-Chin Yao, Grazia Abou Ezzi, PhD, Joseph R. Krambs, BS, Salil Uttarwar, Eric J. Duncavage, MD, Daniel C. Link, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 470.
https://doi.org/10.1182/blood-2019-128943
Published: 2019
Journal Articles

Tudor Domain-Focused CRISPR Dropout Screen Identifies SGF29 As a Novel Essential Gene in MLL -Rearranged Leukemias

Anthony K. N. Chan, PhD, Christopher D. Delaney, Lu Yang, PhD, Wen-Han Chang, PhD, Kazuya Miyashita, PhD, Qiao Liu, MD, Sheela Pangeni Pokharel, MSc, Scott A. Armstrong, MD PhD, Chun-Wei David Chen, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 530.
https://doi.org/10.1182/blood-2019-131467
Published: 2019
Journal Articles

Interrogation of Individual CLL Loss-of-Function Lesions By CRISPR In Vivo Editing Reveals Common and Unique Pathway Alterations

Elisa Ten Hacken, PhD, Shanye Yin, PhD, Kendell Clement, PhD, Robert A. Redd, MS, Maria Hernandez-Sanchez, PhD, Shuqiang Li, PhD, Michaela Gruber, MD PhD, Heather Joyal, Geoffrey Fell, MS, Shu Wang, Jose Jacob, James Flynn, David Ruff, Keith W. Jones, Lili Wang, MD PhD, Donna S Neuberg, ScD, Luca Pinello, PhD, Kenneth J. Livak, PhD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 684.
https://doi.org/10.1182/blood-2019-127673
Published: 2019
Journal Articles

Functional Complementation between β-Catenin and Hoxa9 Sustains HSC Self-Renewal in a Prmt1-Dependent Manner

Jennifer Lynch, PhD, Clemence Virely, PhD, Priscilla Lau, PhD, Huacheng Luo, PhD, Suming Huang, PhD, Eric Chi Wai So, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 449.
https://doi.org/10.1182/blood-2019-131052
Published: 2019
Journal Articles

Loss of METTL3 Mediated m6A RNA Modification Results in Double-Stranded RNA Induced Innate Immune Response and Hematopoietic Failure

Yimeng Gao, PhD, Radovan Vasic, MD, Yuanbin Song, MD, Rhea Teng, B.Sc., Rana Gbyli, MS, Giulia Biancon, PhD, Raman Nelakanti, B.Sc., Eriko Kudo, B.Sc., Wei Liu, PhD, Anastasia Ardasheva, BS, Xiaoying Fu, MD, Xiaman Wang, MD PhD, Poorval Joshi, PhD, Burak Dura, PhD, Veronica Lee, Gabriella Viero, PhD, Akiko Iwasaki, PhD, Rong Fan, PhD, Andrew Xiao, PhD, Richard Flavell, PhD, Hua-Bing Li, PhD, Toma Tebaldi, PhD, Stephanie Halene, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 450.
https://doi.org/10.1182/blood-2019-130442
Published: 2019
Journal Articles

A Single Dose of CD117 Antibody Drug Conjugate Enables Autologous Gene-Modified Hematopoietic Stem Cell Transplant (Gene Therapy) in Nonhuman Primates

John F. Tisdale, MD, Robert E. Donahue, VMD, Naoya Uchida, MD, Bradley R Pearse, PhD, Sean M McDonough, MS, Jennifer L Proctor, BS, Allen Krouse, Nathaniel S. Linde, Aylin C. Bonifacino, Rajiv Panwar, PhD, Ganapathy N. Sarma, PhD, Lena Kien, BS, Kellie Latimer, Junia Dushime, BS, Sharon L. Hyzy, MS, Melissa L. Brooks, BS, Rahul Palchaudhuri, PhD, Qing Li, PhD, Pranoti Sawant, MS, Charlotte F McDonagh, PhD, Anthony E. Boitano, PhD, Michael P. Cooke, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 610.
https://doi.org/10.1182/blood-2019-125968
Published: 2019
Journal Articles

Spatial Mapping of Myelopoiesis Reveals the Bone Marrow Niche for Monocyte Dendritic Cell Progenitors

Jizhou Zhang, Qingqing Wu, PhD, Courtney Johnson, BS, André Olsson, MS, PhD, Anastasiya Slaughter, BA, Margot Lindsay May, BS, Benjamin Weinhaus, BS, Emily Bowers, PhD, James Douglas Engel, PhD, Jean X. Jiang, PhD, Sherry L. Abboud-Werner, PhD, Nathan Salomonis, PhD, H. Leighton Grimes, PhD, Daniel Lucas-Alcaraz, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 528.
https://doi.org/10.1182/blood-2019-128809
Published: 2019
Journal Articles

VCAM1 Confers Innate Immune Tolerance on Hematopoietic and Leukemic Stem Cells

Sandra Pinho, PhD, Qiaozhi Wei, PhD, Maria Maryanovich, PhD, Halley Pierce, PhD, Fumio Nakahara, MD PhD, Jianing Xu, PhD, Daniel K. Borger, MS, Dachuan Zhang, PhD, Amit Verma, MBBS, Paul S. Frenette, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 524.
https://doi.org/10.1182/blood-2019-123431
Published: 2019
Journal Articles

Azacitidine for Pre-Emptive Treatment of Measurable-Residual Disease in MDS/AML Patients at High Risk of Hematological Relapse: Results of the Second Cohort of the RELAZA2 Trial

Uwe Platzbecker, MD, Jan Moritz Middeke, MD, Katja Sockel, MD, Regina Herbst, MD, Lars R. Fransecky, MD, Dominik Wolf, MD, Schumacher Martin, MD, Alwin Krämer, MD, Richard Noppeney, MD, Juergen Novotny, MD, Gesine Bug, Katharina Götze, Karsten Spiekermann, MD, Matthias Stelljes, MD, Christoph Groth, MD, Marion Subklewe, MD, Antje Schubert, Anke Mütherig, MD, Tilmann Bochtler, MD, Marika Mende, MD, Anne Sophie Kubasch, MD, Mathias Hänel, MD, Ulrich Dührsen, Prof, MD PhD, Johannes Schetelig, MD MSc, Christoph Röllig, MD MSC, Claudia D Baldus, Gerhard Ehninger, MD, Carsten Müller-Tidow, MD, Hubert Serve, MD, Michael Kramer, M.Sc., Martin Bornhäuser, MD, Christian Thiede, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 644.
https://doi.org/10.1182/blood-2019-129926
Published: 2019
Journal Articles

DNMT3A R882 Alters the Epigenome of Hematopoietic Cells

Amanda M Smith, PhD, Taylor LaValle, BS, Shamika Ketkar, PhD, Sai Mukund Ramakrishnan, MS, Christopher A Miller, PhD, Timothy J Ley, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 112.
https://doi.org/10.1182/blood-2019-129003
Published: 2019
Journal Articles

Formin Links Erythroid Cytoskeleton to Organelle Clearance through Escrt-III Complex during Reticulocyte Maturation

Yijie Liu, PhD, Haiyan Bao, MD, Yang Mei, PhD, Xu Han, PhD, Peng Ji, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 151.
https://doi.org/10.1182/blood-2019-125157
Published: 2019
Journal Articles

Elucidating an Erythroblast Survival Mechanism: Differential Contributions of Exosome Complex Catalytic Subunits

Charu Mehta, MS, Isabela J Fraga de Andrade, Bachelors in Biological Science, Nobuyuki Tanimura, PhD, Gary M Wilson, Erik A. Ranheim, MD PhD, Joshua J Coon, PhD, Emery H Bresnick, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 155.
https://doi.org/10.1182/blood-2019-126917
Published: 2019
Journal Articles

CD93-Signaling Regulates Self-Renewal and Proliferation of Chronic Myeloid Leukemia Stem Cells in Mice and Humans and Might be a Promising Target for Treatment

Carsten Riether, PhD, Ramin Radpour, PhD, Chantal L. Bachmann, MSc, Christian M Schürch, MD PhD, Miroslav Arambasic, PhD, Gabriela M Baerlocher, MD, Adrian F Ochsenbein, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 187.
https://doi.org/10.1182/blood-2019-127864
Published: 2019
Journal Articles

Complete Spatial Mapping of Steady-State Erythropoiesis

Qingqing Wu, PhD, Jizhou Zhang, Courtney Johnson, BS, Anastasiya Slaughter, BA, Margot Lindsay May, BS, Daniel Lucas-Alcaraz, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 274.
https://doi.org/10.1182/blood-2019-129122
Published: 2019
Journal Articles

Developmental Plasticity of Acute Myeloid Leukemia Mediates Resistance to Venetoclax-Based Therapy

Shanshan Pei, PhD, Daniel A Pollyea, MD, Annika Gustafson, Mohammad Minhajuddin, PhD, Brett M. Stevens, PhD, Haobin Ye, PhD, Anagha Inguva, BSc, Maria L Amaya, MD PhD, Anna Krug, BS, Courtney L Jones, PhD, Biniam Adane, PhD, Amanda Winters, MD PhD, Nabilah Khan, Jessica Ponder, PhD, Jeffrey Schowinsky, Andrew Hammes, MS, Diana Abbott, PhD, Jason R Myers, MS, John M Ashton, PhD, Jonathan A Gutman, MD, Enkhtsetseg Purev, MD PhD, Haley E. Ramsey, PhDMSc, Michael R. Savona, MD, Stephen W. Fesik, PhD, Clayton Smith, MD, Craig T Jordan, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 185.
https://doi.org/10.1182/blood-2019-131390
Published: 2019