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Journal Articles

VISTA Is a Novel Regulator of Macrophage Biology

Parth Shah, MD, Mohamed Eltanbouly, BSc, Nicole Smits, Aurelien Sarde, Randolph Noelle, Rodwell Mabaera, MD PhD

Blood (2019) 134 (Supplement_1): 2320.

https://doi.org/10.1182/blood-2019-131310

Published: 2019

Journal Articles

High Expression of the Resistant Factor YY1 and Low Expression of the RKIP Chemosensitizing Factor in Multiple Myeloma: Delineation of Several Crosstalk Pathways That Regulate the Expression of These Factors

Stephanie Wottrich, Bachelor of Science, Samantha Kaufhold, Bachelor of Science, Stavroula Baritaki, PhD, Benjamin Bonavida, PhD

Blood (2017) 130 (Supplement 1): 5417.

https://doi.org/10.1182/blood.V130.Suppl_1.5417.5417

Published: 2017

Journal Articles

Regulation of Drug Resistance Via the Overexpression of Phopho-RKIP (P-RKIP) in Multiple Myeloma: Dephosphorylation of P-RKIP Reverses Drug Resistance

Devasis Chatterjee, Ph. D, Stavroula Baritaki, PhD, Benjamin Bonavida, PhD

Blood (2017) 130 (Supplement 1): 4971.

https://doi.org/10.1182/blood.V130.Suppl_1.4971.4971

Published: 2017

Journal Articles

Overexpression of Raf Kinase Inhibitor Protein (RKIP) in Multiple Myeloma and Its Molecular Signature

Anna Shvartsur, Hermes Garban, MD PhD, Benjamin Bonavida, PhD

Blood (2016) 128 (22): 5673.

https://doi.org/10.1182/blood.V128.22.5673.5673

Published: 2016

Journal Articles

A Bioinformatics Approach Revealed a Differential Expression of RKIP-Related Genes in Pre-Multiple Myeloma and Multiple Myeloma: Clinical Implications

Anna Shvartsur, Devasis Chatterjee, PhD, Haiming Chen, MD PhD, James Berenson, MD, Hermes Garban, MD PhD, Benjamin Bonavida, PhD

Blood (2015) 126 (23): 5309.

https://doi.org/10.1182/blood.V126.23.5309.5309

Published: 2015

Journal Articles

The Oxazolidinone Derivative Locostatin Induces Apoptosis in CLL Cells through Inhibition of AKT and MAPK-ERK1/2 Signaling Under Conditions That Mimic the Tumor Microenvironment

Oliver Giles Best, PhDBSc, Tahni Pyke, BSc (Hons), Kyle Crassini, MBBS,BSc, William S Stevenson, MBBS, PhD, Stephen P. Mulligan, MBBS (Hons), PhD, FRACP, FRCPA

Blood (2014) 124 (21): 3326.

https://doi.org/10.1182/blood.V124.21.3326.3326

Published: 2014

Journal Articles

The Overexpression of Inactive Phosphorylated Raf-1 Kinase Inhibitory Protein (RKIP) in Multiple Myeloma (MM) Regulates the Resistance to Bortezomib-Induced Cytotoxicity: Reversal of Resistance by the PKC Inhibitor Bisindolylmalemide

Sara Huerta-Yepez, PhD, Stavroula Baritaki, PhD, Hong Liu, Karla MC Mendez-Maldonado, B.S., Manuel L Penichet, M.D., Ph.D., Mario I Vega, PhD, Otoniel Martinez-Maza, PhD, Haiming Chen, James R. Berenson, MD, Devasis Chatterjee, PhD, Benjamin Bonavida, Ph.D

Blood (2011) 118 (21): 2892.

https://doi.org/10.1182/blood.V118.21.2892.2892

Published: 2011

Journal Articles

The Anti-CD 20 Mab R603 Induces PTEN and RKIP Expression in B-NHL Cells: Role in Inhibition of Constitutively Activated Akt and NF-ΚB Survival Anti-Apoptotic Pathways.

Loredana Militello, Stavroula Baritaki, Eriko Suzuki, Mario I. Vega, PhD, Margarita Salcedo, Benjamin Bonavida, PhD

Blood (2009) 114 (22): 1970.

https://doi.org/10.1182/blood.V114.22.1970.1970

Published: 2009

Journal Articles

Inhibition of the RKIP and PTEN-Transcription Repressor Snail in B-NHL by the Proteasome Inhibitor NPI-0052: Roles of RKIP and PTEN Induction in the Reversal of Resistance to TRAIL Apoptosis.

Stavroula Baritaki, Kam Yeung, Ph.D., Katherine Wu, Haiming Chen, MD, PhD, James R. Berenson, MD, Michael A. Palladino, PhD, Benjamin Bonavida, PhD

Blood (2009) 114 (22): 3938.

https://doi.org/10.1182/blood.V114.22.3938.3938

Published: 2009

Journal Articles

Unique Pattern of Raf-1 Kinase Inhibitory Protein (RKIP) Expression in Multiple Myeloma (MM): RKIP Overexpression and RKIP Phosphorylation Is Common in MM Tumor Cells

Stavroula Baritaki, Ph.D., Sara Huerta-Yepez, Ph.D., Ma de Lourdes Cabera-Muñoz, MD, Clara Rivera-Pazos, MD, Kam Yeung, Ph.D., Manuel L Penichet, M.D., Ph.D., Haiming Chen, MD, PhD, James R. Berenson, MD, Benjamin Bonavida, PhD

Blood (2008) 112 (11): 2729.

https://doi.org/10.1182/blood.V112.11.2729.2729

Published: 2008

Journal Articles

Raf1 Is Required for Induction of a Bcr-Abl Positive CML Like Myeloproliferative Disease in Mice

Corinna Albers, Anna Lena Illert, MD, Cornelius Miething, MD, Christian Peschel, MD, Justus Duyster, MD

Blood (2008) 112 (11): 3207.

https://doi.org/10.1182/blood.V112.11.3207.3207

Published: 2008

Journal Articles

The Novel Proteasome Inhibitor NPI-0052 Induces the Expression of Raf-1 Kinase Inhibitor Protein RKIP) in B-NHL via Inhibition of the Transcription Repressor Snail: Roles of Snail and RKIP in Sensitization to TRAIL Apoptosis

Stavroula Baritaki, Aaron Chapman, Katherine Wu, Kam Yeung, Ph.D., Demetrios Spandidos, Ph.D., James R. Berenson, MD, Michael A. Palladino, MS, PhD, Benjamin Bonavida, PhD

Blood (2008) 112 (11): 2611.

https://doi.org/10.1182/blood.V112.11.2611.2611

Published: 2008

Journal Articles

Inhibition of NF-Kb Cell Signaling and Induction of the Metastasis Suppressor and Immune Surveillance Cancer Gene RKIP Expression in B-NHL by the Novel Humanized BM-Ca Anti-CD20 Monoclonal Antibody: Implication in Chemo and Immune-Sensitization

Mario I Vega, Ph.D., Melisa Martinez-Paniagua, Sara Huerta-Yepez, PhD., Benjamin Bonavida, PhD

Blood (2008) 112 (11): 2613.

https://doi.org/10.1182/blood.V112.11.2613.2613

Published: 2008

Journal Articles

Galiximab (anti-CD80 mAb)-Induced Cell Triggering Results in the Inhibition of Constitutive NF-Kb Activity in Raji: Contrasting Roles of Snail and RKIP in the Regulation of Drug/Immune Resistance

Melisa Martinez-Paniagua, Mario I. Vega, PhD, Sara Huerta-Yepez, PhD., Stavroula Baritaki, James R. Berenson, MD, Haris Hariharan, Benjamin Bonavida, PhD

Blood (2008) 112 (11): 3623.

https://doi.org/10.1182/blood.V112.11.3623.3623

Published: 2008

Journal Articles

Synergy in Apoptosis Is Achieved in B-NHL by the Combination of Rituximab and the Novel Proteasome Inhibitor NPI-0052: Pivotal Role of Induction of the Immune Surveillance Cancer Gene Product RKIP

Mario I. Vega, PhD, Melisa Martinez- Paniagua, Sara Huerta-Yepez, PhD., Eriko Suzuki, Kazuo Umezawa, Kam Yeung, Ph.D., Massimo Libra, Stavroula Baritaki, Michael A. Palladino, PhD, Benjamin Bonavida, PhD

Blood (2008) 112 (11): 4973.

https://doi.org/10.1182/blood.V112.11.4973.4973

Published: 2008

Journal Articles

Molecular Mechanism by Which Rituximab Sensitizes B-NHL Cells to TRAIL Apoptosis: Induction of RKIP and DR5 Expression Via Inhibition of NF-Kb, Snail, and YY1.

Mario I. Vega, PhD, Melisa Martinez-Paniagua, Sara Huerta-Yepez, PhD., Yeung Kam, Stavroula Baritaki, Benjamin Bonavida, PhD

Blood (2008) 112 (11): 1596.

https://doi.org/10.1182/blood.V112.11.1596.1596

Published: 2008

Journal Articles

Unique Pattern of Raf-1 Kinase Inhibitory Protein (RKIP) Expression in Multiple Myeloma (MM) Compared to Other Tumor Types: Overexpression of RKIP and a Phosphorylated RKIP Is Common in MM Tumor Cells.

Stavroula Baritaki, Sara Huerta-Yepez, Kam Yeung, Manuel Penichet, Haiming Chen, Dror Shalitin, James Berenson, Benjamin Bonavida

Blood (2007) 110 (11): 4852.

https://doi.org/10.1182/blood.V110.11.4852.4852

Published: 2007

Journal Articles

PKC zeta-mTOR Pathway: A New Target for Rituximab Therapy in Follicular Lymphoma.

Guy Laurent, MD, PhD, Ludivine Leseux, PhD, Camille Laurent, MD, Christine Bezombes, PhD

Blood (2007) 110 (11): 804.

https://doi.org/10.1182/blood.V110.11.804.804

Published: 2007

Journal Articles

Induction of Raf-1 Kinase Inhibitory Protein (RKIP) by the Proteasome Inhibitor NPI-0052 and Reversal of B-NHL Resistance to Apoptosis.

Stavroula Baritaki, Kam Yeung, Devasis Chatterjee, Michel Palladino, Benjamin Bonavida

Blood (2007) 110 (11): 809.

https://doi.org/10.1182/blood.V110.11.809.809

Published: 2007

Journal Articles

Raf Inhibitor BAY 43-9006 Induces Bim Dephosphorylation and Activates the Intracellular Apoptotic Pathway in AML.

Weiguo Zhang, MD, PhD, Marina Konopleva, MD, PhD, Teresa McQueen, BS, Jorje Cortes, MD, James McCubrey, PhD, Michael Andreeff, MD, PhD

Blood (2005) 106 (11): 3367.

https://doi.org/10.1182/blood.V106.11.3367.3367

Published: 2005

NARROW

VISTA Is a Novel Regulator of Macrophage Biology

High Expression of the Resistant Factor YY1 and Low Expression of the RKIP Chemosensitizing Factor in Multiple Myeloma: Delineation of Several Crosstalk Pathways That Regulate the Expression of These Factors

Regulation of Drug Resistance Via the Overexpression of Phopho-RKIP (P-RKIP) in Multiple Myeloma: Dephosphorylation of P-RKIP Reverses Drug Resistance

Overexpression of Raf Kinase Inhibitor Protein (RKIP) in Multiple Myeloma and Its Molecular Signature

A Bioinformatics Approach Revealed a Differential Expression of RKIP-Related Genes in Pre-Multiple Myeloma and Multiple Myeloma: Clinical Implications

The Oxazolidinone Derivative Locostatin Induces Apoptosis in CLL Cells through Inhibition of AKT and MAPK-ERK1/2 Signaling Under Conditions That Mimic the Tumor Microenvironment

The Overexpression of Inactive Phosphorylated Raf-1 Kinase Inhibitory Protein (RKIP) in Multiple Myeloma (MM) Regulates the Resistance to Bortezomib-Induced Cytotoxicity: Reversal of Resistance by the PKC Inhibitor Bisindolylmalemide

The Anti-CD 20 Mab R603 Induces PTEN and RKIP Expression in B-NHL Cells: Role in Inhibition of Constitutively Activated Akt and NF-ΚB Survival Anti-Apoptotic Pathways.

Inhibition of the RKIP and PTEN-Transcription Repressor Snail in B-NHL by the Proteasome Inhibitor NPI-0052: Roles of RKIP and PTEN Induction in the Reversal of Resistance to TRAIL Apoptosis.

Unique Pattern of Raf-1 Kinase Inhibitory Protein (RKIP) Expression in Multiple Myeloma (MM): RKIP Overexpression and RKIP Phosphorylation Is Common in MM Tumor Cells

Raf1 Is Required for Induction of a Bcr-Abl Positive CML Like Myeloproliferative Disease in Mice

The Novel Proteasome Inhibitor NPI-0052 Induces the Expression of Raf-1 Kinase Inhibitor Protein RKIP) in B-NHL via Inhibition of the Transcription Repressor Snail: Roles of Snail and RKIP in Sensitization to TRAIL Apoptosis

Inhibition of NF-Kb Cell Signaling and Induction of the Metastasis Suppressor and Immune Surveillance Cancer Gene RKIP Expression in B-NHL by the Novel Humanized BM-Ca Anti-CD20 Monoclonal Antibody: Implication in Chemo and Immune-Sensitization

Galiximab (anti-CD80 mAb)-Induced Cell Triggering Results in the Inhibition of Constitutive NF-Kb Activity in Raji: Contrasting Roles of Snail and RKIP in the Regulation of Drug/Immune Resistance

Synergy in Apoptosis Is Achieved in B-NHL by the Combination of Rituximab and the Novel Proteasome Inhibitor NPI-0052: Pivotal Role of Induction of the Immune Surveillance Cancer Gene Product RKIP

Molecular Mechanism by Which Rituximab Sensitizes B-NHL Cells to TRAIL Apoptosis: Induction of RKIP and DR5 Expression Via Inhibition of NF-Kb, Snail, and YY1.

Unique Pattern of Raf-1 Kinase Inhibitory Protein (RKIP) Expression in Multiple Myeloma (MM) Compared to Other Tumor Types: Overexpression of RKIP and a Phosphorylated RKIP Is Common in MM Tumor Cells.

PKC zeta-mTOR Pathway: A New Target for Rituximab Therapy in Follicular Lymphoma.

Induction of Raf-1 Kinase Inhibitory Protein (RKIP) by the Proteasome Inhibitor NPI-0052 and Reversal of B-NHL Resistance to Apoptosis.

Raf Inhibitor BAY 43-9006 Induces Bim Dephosphorylation and Activates the Intracellular Apoptotic Pathway in AML.

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American Society of Hematology

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American Society of Hematology

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