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Journal Articles

Dysregulated IL-6/GP130/JAK Signaling in Calreticulin Mutated Myeloproliferative Neoplasms (MPN)

Manjola Balliu, PhD, Laura Calabresi, PhD, Niccolò Bartalucci, PhDBSc, Laura Maggi, PhD, Francesco Annunziato, PhD, Paola Guglielmelli, MD PhD, Alessandro M. Vannucchi, MD

Blood (2019) 134 (Supplement_1): 471.

https://doi.org/10.1182/blood-2019-123685

Published: 2019

Journal Articles

The Novel Role That Nrf2 Plays in Erythropoiesis during Aging

Serge Cedrick Toya Mbiandjeu, Alessandro Mattè, BSc,PhD, Enrica Federti, PhD, Massimiliano Perduca, Immacolata Andolfo, Achille Iolascon, MD PhD, Maria Teresa Valenti, PhD, Arianna Pisani, Luca Dalle Carbonare, MD, Pietro Pucci, Angela Amoresano, Mohandas Narla, DSc, Lucia De Franceschi, MD

Blood (2019) 134 (Supplement_1): 3502.

https://doi.org/10.1182/blood-2019-125920

Published: 2019

Journal Articles

Providing a Homing Receptor for CAR Engineered NK Cells - Improving Cellular Immunotherapy for B-Cell Lymphoma

Nathan Thomas Schomer, BS, MS, Laurent Boissel, PhD, Karen Jiang, PhD, Hans Klingemann, MD PhD, John H. Lee, MD F.A.C.S, Patrick Soon-Shiong, MD FRCS(C), FACS

Blood (2018) 132 (Supplement 1): 4547.

https://doi.org/10.1182/blood-2018-99-116890

Published: 2018

Journal Articles

ER-Stress-Induced Suppression of HLA-E on Bortezomib-Evading Malignant Plasma Cells Dramatically Enhances Their Susceptibility to NK Cell Killing: Identification of an Achilles Heel in Myeloma Cells That Can be Utilized to Prevent Disease Relapse Following Bortezomib Treatment

Mattias Carlsten, MD, PhD, Ali Namazi, MD, Robert N. Reger, B.S., Maria Berg, Richard W. Childs, MD

Blood (2015) 126 (23): 4296.

https://doi.org/10.1182/blood.V126.23.4296.4296

Published: 2015

Journal Articles

Selectively Targeting Mutated NOTCH1 with a Folate-Thapsigargin Derivative

Giovanni Roti, MD, Jun Qi, PhD, Angela Su, B.S., Antony Varca, B.S., Jon C Aster, MD PhD, James E. Bradner, Kimberly Stegmaier, MD

Blood (2014) 124 (21): 2158.

https://doi.org/10.1182/blood.V124.21.2158.2158

Published: 2014

Journal Articles

Pre-Clinical Activity of the Novel, First-in-Class p97 Inhibitor, CB-5083, in Multiple Myeloma

Blood (2014) 124 (21): 4701.

https://doi.org/10.1182/blood.V124.21.4701.4701

Published: 2014

Journal Articles

The Genomic Landscape of Myeloproliferative Neoplasms: Somatic Calr Mutations in the Majority of JAK2-Wildtype Patients

Jyoti Nangalia, MBBChir FRCPath, Charles Massie, PhD, E Joanna Baxter, PhD, Francesca L Nice, MRes, Gunes Gundem, PhD, David Wedge, PhD, Edward Avezov, PhD, Juan Li, PhD, Karoline Kollmann, PhD, David G. Kent, PhD, Athar Aziz, PhD, Anna L Godfrey, BMBCh FRCPath, Jonathan Hinton, MSc, Inigo Martincorena, PhD, Peter Van Loo, PhD, Amy V Jones, PhD, Paola Guglielmelli, PhD MD, Patrick Tarpey, PhD, Heather P Harding, PhD, John D Fitzpatrick, BA, Calum T Goudie, BA, Christina A Ortmann, MD, Stephen J Loughran, PhD, Keiran Raine, MSc, David Jones, MSc, Adam Butler, MSc, Jon W Teague, MSc, Sarah O'Meara, Stuart McLaren, Michele Bianchi, Yvonne Silber, MSc, Danai Dimitropolou, BSc, David Bloxham, MSc FRCPath, Laura J Mudie, BSc, Mark Maddison, BSc, Ben Robinson, BSc, Clodagh Keohane, MD, Cathy MacLean, MSc, Kate Hill, BM BS, Kim H. Orchard, MBBS, PhD, FRCP, FRCPath, Sudhir Tauro, PhD, Ming-Qing Du, MB, PhD, Mel Greaves, PhD, FRS, David Bowen, MD, PhD, Brian Huntly, MBChB FRCPath PhD, Claire N Harrison, DM, FRCP, FRCPath, Nicholas C.P. Cross, PhD, FRCPath, David Ron, MD, Alessandro M Vannucchi, MD, Elli Papaemmanuil, PhD, Peter J. Campbell, PhD, Anthony R Green, FRCPath FMedSci

Blood (2013) 122 (21): LBA-2.

https://doi.org/10.1182/blood.V122.21.LBA-2.LBA-2

Published: 2013

Journal Articles

Macrolide Antibiotics Block Autophagy Flux and Sensitize to Bortezomib Via Endoplasmic Reticulum-Stress-Mediated CHOP Induction in Myeloma Cells

Shota Moriya, Xiao-Fang Che, MD, PhD, Seiichiro Komatsu, MD, Akihisa Abe, PhD, Tomohiro Kawaguchi, Akihiko Gotoh, MD, PhD, Masato Inazu, PhD, Akio Tomoda, MD, PhD, Keisuke Miyazawa, MD, PhD

Blood (2012) 120 (21): 4992.

https://doi.org/10.1182/blood.V120.21.4992.4992

Published: 2012

Journal Articles

A Germline Mutation in Cathepsin B in a Child with ALL Points towards a Key Role for This Enzyme in L-Asparaginase Pharmacokinetics.

Laurens T. van der Meer, PhD, Esmé Waanders, PhD, Marloes Levers, BSc, Hanka Venselaar, MSc, Debbie Roeleveld, BSc, Joachim Boos, MD, PhD, Claudia Lanvers-Kaminsky, PhD, Roland P. Kuiper, PhD, Peter M. Hoogerbrugge, MD, PhD, Frank N. van Leeuwen, PhD, D. Maroeska W.M. te Loo, MD, PhD

Blood (2012) 120 (21): 2458.

https://doi.org/10.1182/blood.V120.21.2458.2458

Published: 2012

Journal Articles

ERN1/IRE1 and XBP1 Are Dispensable for Myeloma Cell Survival but Are Required for the Anti-Myeloma Activity of Bortezomib

Chungyee Leung-Hagesteijn, MSc, Brad Wouters, PhD, Rodger E. Tiedemann, MD PhD FRACP FRCPA

Blood (2011) 118 (21): 986.

https://doi.org/10.1182/blood.V118.21.986.986

Published: 2011

Journal Articles

Development and Characterization of Recombinant Ovine Factor VIII

Philip M Zakas, Bagirath Gangadharan, MS, Graca Almeida-Porada, MD, PhD, Christopher D Porada, PhD, H. Trent Spencer, PhD, Christopher B Doering, PhD

Blood (2011) 118 (21): 1193.

https://doi.org/10.1182/blood.V118.21.1193.1193

Published: 2011

Journal Articles

Anthracycline Treatment Induces Extracellular Calreticulin in Acute Myeloid Leukemia

Sarah Mans, Kerstin Schaubitzer, PhD, Deborah Shan, Beatrice U Mueller, Thomas Pabst, MD

Blood (2011) 118 (21): 1376.

https://doi.org/10.1182/blood.V118.21.1376.1376

Published: 2011

Journal Articles

Small Leucine Rich Proteoglycans as Novel Tumor Markers In Chronic Lymphocytic Leukemia

Eva Mikaelsson, Mahmood Jeddi-Tehrani, Sr., Anders Ã–Sterborg, MD, PhD, Fazel Shokri, Hodjattallah Rabbani, Håkan Mellstedt

Blood (2010) 116 (21): 694.

https://doi.org/10.1182/blood.V116.21.694.694

Published: 2010

Journal Articles

Insulin-Like Growth Factor 1 Potentiates the Cytotoxic Activity of Bortezomib Against Myeloma Cells

Ines Tagoug, PhD, Lars Jordheim, Pharm, D, PhD, Anne-Laure Huber, PhD, Stephanie Herveau, Eva Matera, Serge Manié, PhD, Charles Dumontet

Blood (2010) 116 (21): 3987.

https://doi.org/10.1182/blood.V116.21.3987.3987

Published: 2010

Journal Articles

The Kinase Inhibitor, PCI-32765, Demonstrates Activity In Chronic Lymphocytic Leukemia Cells Independent of Microenvironmental Survival Signals

Sarah E.M. Herman, Amber L. Gordon, Emilia Mahoney, MD, PhD, Samantha M. Jaglowski, MD, Kristie A. Blum, MD, Joseph Buggy, PhD, Ahmed Hamdy, MD, John C. Byrd, MD, Amy J. Johnson, PhD

Blood (2010) 116 (21): 1385.

https://doi.org/10.1182/blood.V116.21.1385.1385

Published: 2010

Journal Articles

Clinicopathologic Characteristics and Outcome of Histiocytic and Dendritic Cell Neoplasms: A Single Institutional Experience.

Mojdeh Naghashpour, MD, PhD, Reza Setoodeh, MD, Lynn C. Moscinski, MD, Lubomir Sokol, MD, PhD

Blood (2010) 116 (21): 2813.

https://doi.org/10.1182/blood.V116.21.2813.2813

Published: 2010

Journal Articles

Identification of SEC23B as the Gene Responsible for Congenital Dyserythropoietic Anemia Type II using a Proteomic-Genomic Approach.

Paola Bianchi, Elisa Fermo, Cristina Vercellati, Carla Boschetti, Wilma Barcellini, Alessandra Iurlo, Anna Paola Marcello, Pier Giorgio Righetti, Alberto Zanella

Blood (2009) 114 (22): 4028.

https://doi.org/10.1182/blood.V114.22.4028.4028

Published: 2009

Journal Articles

Evidence for Reduced Angiogenesis in Bone Marrow of Systemic Sclerosis Patients Immunohistochemetry and Computerized Imagine Analysis.

Valentina Carrai, Renato Alterini, Riccardo Saccardi, Irene Miniati, Luigi Rigacci, Gloria Capaccioli, Irene Donnini, Giada Rotunno, Alberto Bosi, Marco Matucci Cerinic

Blood (2009) 114 (22): 5126.

https://doi.org/10.1182/blood.V114.22.5126.5126

Published: 2009

Journal Articles

Characterization of Five Homozygous ADAMTS13 Mutations in Hereditary Thrombotic Thrombocytopenic Purpura – Towards a Phenotype-Genotype Correlation?

Sara C Meyer, Shengyu Jin, Wenjing Cao, X. Long Zheng, Bernhard Lammle, Johanna A Kremer Hovinga

Blood (2008) 112 (11): 274.

https://doi.org/10.1182/blood.V112.11.274.274

Published: 2008

Journal Articles

Targeting Autophagy Potentiates Imatinib-Induced Cell Death in Philadelphia Positive Cells Including Primary CML Stem Cells.

Blood (2008) 112 (11): 1070.

https://doi.org/10.1182/blood.V112.11.1070.1070

Published: 2008

NARROW

Dysregulated IL-6/GP130/JAK Signaling in Calreticulin Mutated Myeloproliferative Neoplasms (MPN)

The Novel Role That Nrf2 Plays in Erythropoiesis during Aging

Providing a Homing Receptor for CAR Engineered NK Cells - Improving Cellular Immunotherapy for B-Cell Lymphoma

ER-Stress-Induced Suppression of HLA-E on Bortezomib-Evading Malignant Plasma Cells Dramatically Enhances Their Susceptibility to NK Cell Killing: Identification of an Achilles Heel in Myeloma Cells That Can be Utilized to Prevent Disease Relapse Following Bortezomib Treatment

Selectively Targeting Mutated NOTCH1 with a Folate-Thapsigargin Derivative

Pre-Clinical Activity of the Novel, First-in-Class p97 Inhibitor, CB-5083, in Multiple Myeloma

The Genomic Landscape of Myeloproliferative Neoplasms: Somatic Calr Mutations in the Majority of JAK2-Wildtype Patients

Macrolide Antibiotics Block Autophagy Flux and Sensitize to Bortezomib Via Endoplasmic Reticulum-Stress-Mediated CHOP Induction in Myeloma Cells

A Germline Mutation in Cathepsin B in a Child with ALL Points towards a Key Role for This Enzyme in L-Asparaginase Pharmacokinetics.

ERN1/IRE1 and XBP1 Are Dispensable for Myeloma Cell Survival but Are Required for the Anti-Myeloma Activity of Bortezomib

Development and Characterization of Recombinant Ovine Factor VIII

Anthracycline Treatment Induces Extracellular Calreticulin in Acute Myeloid Leukemia

Small Leucine Rich Proteoglycans as Novel Tumor Markers In Chronic Lymphocytic Leukemia

Insulin-Like Growth Factor 1 Potentiates the Cytotoxic Activity of Bortezomib Against Myeloma Cells

The Kinase Inhibitor, PCI-32765, Demonstrates Activity In Chronic Lymphocytic Leukemia Cells Independent of Microenvironmental Survival Signals

Clinicopathologic Characteristics and Outcome of Histiocytic and Dendritic Cell Neoplasms: A Single Institutional Experience.

Identification of SEC23B as the Gene Responsible for Congenital Dyserythropoietic Anemia Type II using a Proteomic-Genomic Approach.

Evidence for Reduced Angiogenesis in Bone Marrow of Systemic Sclerosis Patients Immunohistochemetry and Computerized Imagine Analysis.

Characterization of Five Homozygous ADAMTS13 Mutations in Hereditary Thrombotic Thrombocytopenic Purpura – Towards a Phenotype-Genotype Correlation?

Targeting Autophagy Potentiates Imatinib-Induced Cell Death in Philadelphia Positive Cells Including Primary CML Stem Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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