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Journal Articles

Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and -independent effects by CDK6-specific PROTACs

Marco De Dominici, Patrizia Porazzi, Youcai Xiao, Allen Chao, Hsin-Yao Tang, Gaurav Kumar, Paolo Fortina, Orietta Spinelli, Alessandro Rambaldi, Luke F. Peterson, Svetlana Petruk, Camilla Barletta, Alexander Mazo, Gino Cingolani, Joseph M. Salvino, Bruno Calabretta

Blood (2020) 135 (18): 1560–1573.

https://doi.org/10.1182/blood.2019003604

Published: 2020

Includes: Supplemental data

Journal Articles

Codanin-1 Mutations Engineered in Human Erythroid Cells Allow Investigation of Mechanisms Underlying Congenital Dyserythropoietic Anemia

Zachary C. Murphy, PhD, Michael Getman, MS, Jacquelyn Lillis, Laurie A. Steiner, MD

Blood (2019) 134 (Supplement_1): 3739.

https://doi.org/10.1182/blood-2019-127415

Published: 2019

Journal Articles

Robust Hematopoietic Stem Cell Function and Minimal Myeloid Skewing with Aging in Un-Separated Murine Whole Bone Marrow: What Are We Losing with Hematopoietic Stem Cell Purification?

Mark S Dooner, Elaine Papa, Michael Del Tatto, Mandy Pereira, Sicheng Wen, MD PhD, Yan Cheng, PhD, Peter J. Quesenberry, MD, Laura R Goldberg, MD PhD

Blood (2019) 134 (Supplement_1): 3723.

https://doi.org/10.1182/blood-2019-124367

Published: 2019

Journal Articles

S-Phase Progression of North American ATLL Cells Is Critically Regulated By the Proto-Oncogene BCL6 and Targetable By PARP Inhibition

B. Hilda Ye, PhD, Elaine Chung, PhD, Kith Pradhan, PhD, Ana Acuna-Villaorduna, MD, Yanhua Wang, MD PhD, Aditi Shastri, MD, Advaitha Madireddy, PhD, Amit Verma, MBBS, R.Alejandro Sica, MD, Murali Janakiram, MD MS

Blood (2019) 134 (Supplement_1): 3779.

https://doi.org/10.1182/blood-2019-131364

Published: 2019

Journal Articles

DNMT3A with Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

Kartika Venugopal, MS, Daniil E Shabashvili, PhD, Jianping Li, MD, Luisa M Posada, Richard Lynn Bennett, PhD, Yang Feng, MS, Daphne Dupere Richer, PhD, Alberto Riva, PhD, Santhi Pondugula, PhD, Jonathan E. Bird, PhD, Jonathan D. Licht, MD, Olga A Guryanova, MD PhD

Blood (2019) 134 (Supplement_1): 535.

https://doi.org/10.1182/blood-2019-128213

Published: 2019

Journal Articles

RASA3 Is Essential for Early Mammalian Hematopoiesis and Modulates ERK Signaling in Terminal Erythropoiesis

Elena C. Brindley, BS, Raymond F. Robledo, PhD, Steven L. Ciciotte, MS, Joel H. Graber, PhD, Yue Zhao, Emily Hartman, BS, Julien Papoin, MS, Lionel Blanc, PhD, Luanne L. Peters, PhD

Blood (2019) 134 (Supplement_1): 3505.

https://doi.org/10.1182/blood-2019-130328

Published: 2019

Journal Articles

Blood Cell Fate Decisions: Insights from Single-cell RNA-seq

Merav Socolovsky, MBBS, PhD

Blood (2019) 134 (Supplement_1): SCI-20.

https://doi.org/10.1182/blood-2019-121106

Published: 2019

Journal Articles

Suppression of CUL4B Induces G1 Cell Cycle Arrest through the Modulation of AKT Signaling Pathway

Ying Li, MD, Ya Zhang, MD, Xiangxiang Zhou, MD, Xin Wang, MDPhD

Blood (2018) 132 (Supplement 1): 5133.

https://doi.org/10.1182/blood-2018-99-118442

Published: 2018

Journal Articles

Targeted Disruption of the Cohesin Subunit STAG2 Leads to Loss of Insulation and Inappropriate Gene Activation in Response to Differentiation Signals

Jisha Antony, PhD, Gregory Giminez, PhD, Umaima Khatoon, BSc (Hons), Robert Day, PhD, Ian Morison, PhD, FRCPA, MBBS, Julia Horsfield, PhD

Blood (2018) 132 (Supplement 1): 878.

https://doi.org/10.1182/blood-2018-99-117965

Published: 2018

Journal Articles

Genetic or Pharmacological Inhibition of the Polycomb Group Protein BMI1 Impairs Leukemic Transformation Mediated By the CALM-AF10 Fusion Oncoprotein

Karina O. Barbosa, BSc, Anwesha Ghosh, PhD, Anagha Deshpande, PhD, Sayantanee Dutta, PhD, Scott A. Armstrong, MD PhD, Stefan K. Bohlander, MD, Aniruddha J. Deshpande, PhD

Blood (2018) 132 (Supplement 1): 762.

https://doi.org/10.1182/blood-2018-99-115552

Published: 2018

Journal Articles

Single Cell RNASeq Demonstrates That Mouse Erythroid Cells Are the Last Lineage to Emerge

Elisabeth F Heuston, PhD, Bethan Psaila, MD PhD, Stacie M Anderson, NISC Comparative Sequencing Program, David M. Bodine, PhD

Blood (2018) 132 (Supplement 1): 1274.

https://doi.org/10.1182/blood-2018-99-110318

Published: 2018

Journal Articles

Enhanced Selective Inhibition of KRAS Mutant Hematopoietic Progenitor Cell Expansion By MEK and Bcl-2 Inhibition

Huan-Ting Lin, PhD, Kenji Kubara, Kazuto Yamazaki, PhD, Masatoshi Takagi, MD PhD, Takuya Naruto, MD PhD, Tomohiro Morio, MD PhD, Takashi Okumura, PhD, Makoto Otsu, MD PhD

Blood (2018) 132 (Supplement 1): 1278.

https://doi.org/10.1182/blood-2018-99-117889

Published: 2018

Journal Articles

Hematopoietic-Specific CSNK2B Loss in Mice Causes Impaired Erythropoiesis

Laura Quotti Tubi, PhD, Sara Canovas Nunes, PhD, Marilena Carrino, PhD, Ketty Gianesin, PhD, Sabrina Manni, PhD, Odile Filhol-Cochet, PhD, Brigitte Boldyreff, PhD, Livio Trentin, MD, Gianpietro Semenzato, MD, Francesco Piazza, MD

Blood (2017) 130 (Supplement 1): 82.

https://doi.org/10.1182/blood.V130.Suppl_1.82.82

Published: 2017

Journal Articles

Long Non-Coding Transcript in LEF1 Locus Is a Novel Regulator of Cell Cycle and Apoptotic Pathways in Myeloid Leukemic Cells

Ada Congrains, PhD, Fernanda Niemann, MSc, João Agostinho Machado-Neto, BSc, Sara Teresinha Olalla Saad, MD PhD

Blood (2017) 130 (Supplement 1): 2480.

https://doi.org/10.1182/blood.V130.Suppl_1.2480.2480

Published: 2017

Journal Articles

A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemic Pathogenesis

Andrew Volk, PhD, Kaiwei Liang, PhD, Jianyun Zhao, Xinyu Li, Marinka Bulic, Stacy Marshall, Jeffrey W. Taub, MD, Yubin Ge, PhD, Sebastien Malinge, PhD, Elizabeth Bartom, PhD, Ali Shilatifard, PhD, John D. Crispino, PhD

Blood (2017) 130 (Supplement 1): 245.

https://doi.org/10.1182/blood.V130.Suppl_1.245.245

Published: 2017

Journal Articles

Global Increase in Replication Fork Speed during a p57 KIP2 -Regulated Erythroid Cell Fate Switch

Yung Hwang, Melinda Futran, Daniel Hidalgo, MA, Divya Ramalingam Iyer, Nicholas Rhind, Merav Socolovsky, MBBS, PhD

Blood (2016) 128 (22): 698.

https://doi.org/10.1182/blood.V128.22.698.698

Published: 2016

Journal Articles

Identification of CCND2 As a RUNX1/ETO Target Required for Leukaemic Propagation

Lynsey McKenzie, PhD, Natalia Martinez-Soria, PhD, Julia Draper, DPhil, Sirintra Nakjang, PhD, Helen J Blair, PhD, Christian Wichmann, MD, Josef Vormoor, MD FRCPCH, Constanze Bonifer, PhD, Georges Lacaud, PhD, Olaf Heidenreich, PhD

Blood (2016) 128 (22): 835.

https://doi.org/10.1182/blood.V128.22.835.835

Published: 2016

Journal Articles

BM-MSC Hhip Induced Microenvironment Protection from Chemotherapy in AML Via Ptch/Smo/Gli Pathwa

Xuejie Jiang, Dan Xu, Fang Chen, Ling Jiang, Guopan Yu, Fanyi Meng, Xiaoli Liu, PhD, Qifa Liu, MD

Blood (2016) 128 (22): 5235.

https://doi.org/10.1182/blood.V128.22.5235.5235

Published: 2016

Journal Articles

Radiation Resistance of Double Knockout (DKO) Smad3-/- Fancd2-/- (129/Sv) Mouse Bone Marrow Stromal Cell Lines

Kevin Keppel, Michael W. Epperly, PhD, Donna Shields, Wen Hou, Darcy Franicola, Zhang Xichen, Renee Fisher, Joel S. Greenberger, MD

Blood (2016) 128 (22): 3901.

https://doi.org/10.1182/blood.V128.22.3901.3901

Published: 2016

Journal Articles

SF3B1 Interactions with Chromatin Are Dynamic and Regulated in a Cell Cycle-Dependent Manner

Tushar Murthy, MS, Theresa Bluemn, Manoj M. Pillai, MD, Alex C Minella, MD

Blood (2016) 128 (22): 1480.

https://doi.org/10.1182/blood.V128.22.1480.1480

Published: 2016

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Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and -independent effects by CDK6-specific PROTACs

Codanin-1 Mutations Engineered in Human Erythroid Cells Allow Investigation of Mechanisms Underlying Congenital Dyserythropoietic Anemia

Robust Hematopoietic Stem Cell Function and Minimal Myeloid Skewing with Aging in Un-Separated Murine Whole Bone Marrow: What Are We Losing with Hematopoietic Stem Cell Purification?

S-Phase Progression of North American ATLL Cells Is Critically Regulated By the Proto-Oncogene BCL6 and Targetable By PARP Inhibition

DNMT3A with Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

RASA3 Is Essential for Early Mammalian Hematopoiesis and Modulates ERK Signaling in Terminal Erythropoiesis

Blood Cell Fate Decisions: Insights from Single-cell RNA-seq

Suppression of CUL4B Induces G1 Cell Cycle Arrest through the Modulation of AKT Signaling Pathway

Targeted Disruption of the Cohesin Subunit STAG2 Leads to Loss of Insulation and Inappropriate Gene Activation in Response to Differentiation Signals

Genetic or Pharmacological Inhibition of the Polycomb Group Protein BMI1 Impairs Leukemic Transformation Mediated By the CALM-AF10 Fusion Oncoprotein

Single Cell RNASeq Demonstrates That Mouse Erythroid Cells Are the Last Lineage to Emerge

Enhanced Selective Inhibition of KRAS Mutant Hematopoietic Progenitor Cell Expansion By MEK and Bcl-2 Inhibition

Hematopoietic-Specific CSNK2B Loss in Mice Causes Impaired Erythropoiesis

Long Non-Coding Transcript in LEF1 Locus Is a Novel Regulator of Cell Cycle and Apoptotic Pathways in Myeloid Leukemic Cells

A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemic Pathogenesis

Global Increase in Replication Fork Speed during a p57 KIP2 -Regulated Erythroid Cell Fate Switch

Identification of CCND2 As a RUNX1/ETO Target Required for Leukaemic Propagation

BM-MSC Hhip Induced Microenvironment Protection from Chemotherapy in AML Via Ptch/Smo/Gli Pathwa

Radiation Resistance of Double Knockout (DKO) Smad3-/- Fancd2-/- (129/Sv) Mouse Bone Marrow Stromal Cell Lines

SF3B1 Interactions with Chromatin Are Dynamic and Regulated in a Cell Cycle-Dependent Manner

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