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Journal Articles

Single Cell Clones Derived from a Patient's AML Xenograft Display Genetic and Functional Heterogeneity

Christina Maria Zeller, MSc, Daniel Richter, MSc, Binje Vick, PhD, Tobias Herold, MD, Johannes Bagnoli, Maja Rothenberg-Thurley, PhD, Klaus H. Metzeler, MD, Karsten Spiekermann, MD, Wolfgang Enard, PhD, Irmela Jeremias, MD PhD

Blood (2019) 134 (Supplement_1): 1450.

https://doi.org/10.1182/blood-2019-127867

Published: 2019

Journal Articles

Generation, Characterization and Pre-Clinical Drug Evaluation of Patient-Derived Xenograft Models of Pediatric Down Syndrome AML

Sonali Barwe, PhD MSc, E. Anders Kolb, MD, Erin Lynn Crowgey, PhD, Todd E Druley, MD PhD, Anilkumar Gopalakrishnapillai, PhD

Blood (2019) 134 (Supplement_1): 2683.

https://doi.org/10.1182/blood-2019-131050

Published: 2019

Journal Articles

Angioimmunoblastic T-Cell Lymphoma: Molecular Characterization of Clonal T and B-Cells and a Patient Derived Xenograft Model of Coexisting T and B-Cell Proliferations

Xiaoxian Zhao, PhD, Bartlomiej Przychodzen, Juraj Bodo, PhD, Lisa Durkin, Daniel Lindner, MD PhD, Neetha Parameswaran, PhD, Michael Clemente, MS, Sarah L. Ondrejka, DO, Jaroslaw P. Maciejewski, MD PhD, Deepa Jagadeesh, MDMPH, Eric D. Hsi, MD

Blood (2019) 134 (Supplement_1): 1572.

https://doi.org/10.1182/blood-2019-129131

Published: 2019

Journal Articles

Metabolism of Acute Myeloid Leukemia Cell Lines Alters with Passage in 2D Culture and Remains Stable in 3D

Sophia Zemenides, BSc, MBBS, MRCP, MSc, Joana Dos Santos, MSc, Louise Enfield, Athanasios Mantalaris, PhD, Nicki Panoskaltsis, MD PhD FRCP

Blood (2018) 132 (Supplement 1): 2787.

https://doi.org/10.1182/blood-2018-99-118648

Published: 2018

Journal Articles

Microrna-126 Levels Modulate B-ALL Aggressiveness but Require Tight Regulation to Guarantee Disease Maintenance

Carolina Caserta, Silvia Nucera, MD, Matteo Maria Naldini, Nadia Foligno, Giacomo Desantis, PhD, Fabio Ciceri, MD, Davide Cittaro, PhD, Bernhard Gentner, MD

Blood (2018) 132 (Supplement 1): 2834.

https://doi.org/10.1182/blood-2018-99-115101

Published: 2018

Journal Articles

Generation and Application of T-Cell Lymphoma Patient Derived Tumor Xenograft Models

Blood (2017) 130 (Supplement 1): 109.

https://doi.org/10.1182/blood.V130.Suppl_1.109.109

Published: 2017

Journal Articles

AML Differentially Alters Fate and Function of Mesenchymal Stem- and Osteolineage Cells in the Leukemic Niche

Ben Doron, BS, Sherif Abdelhamed, PhD, Ryan M Mulqueen, B.S., Julja Burchard, M.S., Andrew Adey, PhD, Peter Kurre, MD

Blood (2017) 130 (Supplement 1): 1197.

https://doi.org/10.1182/blood.V130.Suppl_1.1197.1197

Published: 2017

Journal Articles

VEGFA- a New Therapeutic Target in CNS Leukemia

Blood (2016) 128 (22): 911.

https://doi.org/10.1182/blood.V128.22.911.911

Published: 2016

Journal Articles

A Pharmacologically Reversible Epigenomic Signature of Relapse and Chemotherapy Resistance in Anaplastic Large Cell Lymphoma

Heng Pan, BS, Marcello Gaudiano, Fabrizio Tabbo', Elisa de Stanchina, Peter Martin, MD, Olivier Elemento, PhD, Giorgio Inghirami, MD

Blood (2016) 128 (22): 3932.

https://doi.org/10.1182/blood.V128.22.3932.3932

Published: 2016

Journal Articles

Clinical and Biological Features Associated with Engraftment of Acute Myeloid Leukemia Patient-Derived Xenografts

Giacomo Oliveira, PhD, Gabriele Bucci, PhD, Cristina Toffalori, PhD, Carolina Caserta, Lara Crucitti, MD, Barbara Camisa, BSc, Raffaella Greco, MD, Francesca Biavasco, Lucia Zanotti, PhD, Laura Zito, MSc, Jose Manuel Garcia-Manteiga, PhD, Dejan Lazarevic, MD, Matteo Giovanni Carrabba, MD, Massimo Bernardi, MD, Attilio Bondanza, MD PhD, Chiara Bonini, MD, Fabio Ciceri, MD, Luca Vago, MD PhD

Blood (2016) 128 (22): 2858.

https://doi.org/10.1182/blood.V128.22.2858.2858

Published: 2016

Journal Articles

B and T-Cell Lymphoma Patient-Derived Xenografts Recapitulate Aspects of Disease Biology and Progression and Represent Novel Tools for Preclinical Drug Development

Blood (2015) 126 (23): 4001.

https://doi.org/10.1182/blood.V126.23.4001.4001

Published: 2015

Journal Articles

Lineage Switch As a Relapse Mechanism of Pre-B Acute Lymphoblastic Leukemia Following CD19 CAR

Elad Jacoby, MD, Sang Minh Nguyen, BS, Kathryn M Welp, Haiying Qin, MS, Yinmeng Yang, BS, Christopher Daniel Chien, PhD, John Shern, MD, Terry J. Fry, MD

Blood (2015) 126 (23): 2524.

https://doi.org/10.1182/blood.V126.23.2524.2524

Published: 2015

Journal Articles

Development and Analysis of Novel Intravascular Large B-Cell Lymphoma NOD/Shi- Scid IL2Rγ null Mouse Xenograft Model

Kazuyuki Shimada, MD PhD, Satoko Shimada, MD PhD, Keiki Sugimoto, Fumihiko Hayakawa, MD PhD, Miyuki Katayama, MD PhD, Akihiro Hirakawa, PhD, Yusuke Takagi, MD, Shigeo Nakamura, MD PhD, Masao Seto, MD PhD, Tomoki Naoe, MDPhD, Akihiro Tomita, MD PhD, Hitoshi Kiyoi, MD PhD

Blood (2014) 124 (21): 497.

https://doi.org/10.1182/blood.V124.21.497.497

Published: 2014

Journal Articles

Microenvironmental Contribution to Dysfunctional Hematopoiesis in a Murine Model of Myelodysplastic Syndrome

Sophia R. Balderman, MD, Benjamin J Frisch, PhD, Mark W LaMere, BS, Alexandra N Goodman, BA, Michael W. Becker, MD, Laura M. Calvi, MD

Blood (2014) 124 (21): 4359.

https://doi.org/10.1182/blood.V124.21.4359.4359

Published: 2014

Journal Articles

Identification of Cmtm Family Proteins As Tumor Suppressor and Membrane Regulator in B Cell Precursor Acute Lymphoblastic Leukemia

Jeyanthy Eswaran, PhD, Paul Sinclair, Sirintra Nakjang, PhD, Christine J. Harrison

Blood (2014) 124 (21): 3582.

https://doi.org/10.1182/blood.V124.21.3582.3582

Published: 2014

Journal Articles

Novel Intracranial Xenografts Of CNS Lymphoma Implicate a Role For Cereblon As a Mediator Of Lenalidomide Efficacy

Hua-Xin Gao, Ph.D., Shawn Anderson, Cigall Kadoch, Ph.D., Mekhala Maiti, Ph.D., Lingjing Chen, Ph.D., Dong-Han Yao, Gerd Melkus, Ph.D., Maria Wang, Ph.D., Yan Ren, Ph.D., Michael Breider, Ph.D., Carla Heise, PhD, Clifford A. Lowell, MD, PhD, Colin Collins, Ph.D., James L. Rubenstein, M.D., Ph.D.

Blood (2013) 122 (21): 374.

https://doi.org/10.1182/blood.V122.21.374.374

Published: 2013

Journal Articles

Inhibition Of Telomerase Is a Novel and Effective Therapy In MLL-Rearranged Acute Myeloid Leukemia (AML)

Claudia Bruedigam, Frederik Otzen Bagger, MSc, Catherine Paine Kuhn, Therese Vu, Rebecca Austin, Florian H Heidel, MD, Lars Bullinger, MD, PhD, Geoff R Hill, Scott A. Armstrong, MD, PhD, David A. Williams, MD, Steven W Lane, MD, PhD

Blood (2013) 122 (21): 2887.

https://doi.org/10.1182/blood.V122.21.2887.2887

Published: 2013

Journal Articles

Comparative Analysis of SSEA4 + and SSEA4 − Mesenchymal Stem Cells Derived From Wharton's Jelly of Umbilical Cord

Haiping He, MD., Tokiko Nagamura-Inoue, MD, PhD, Miki Yuzawa, MT., Yuki Yamamoto, MT., Hajime Tsunoda, MD, PhD., Arinobu Tojo, MD, PhD.

Blood (2012) 120 (21): 4735.

https://doi.org/10.1182/blood.V120.21.4735.4735

Published: 2012

Journal Articles

Influence of Different Genetic Alterations On the Engraftment Capacity and Serial Transplantation Efficiency of AML Patient-Derived Bone Marrow and Peripheral Blood Cells in NSG Mice

Julia Schüler, Peter Haas, MD, Kerstin Klingner, Björn W. Hackanson, MD, Heinz-Herbert Fiebig, Michael Lübbert, MD, PhD

Blood (2012) 120 (21): 3511.

https://doi.org/10.1182/blood.V120.21.3511.3511

Published: 2012

Journal Articles

Evolution of Sub-Clones with KRAS Mutations In Pediatric Patients with MLL-AF4 Rearrangements

Silvia Bresolin, Emanuela Giarin, Luca Trentin, PhD, Lueder Hinrich Meyer, MD, Giuseppe Basso, MD PhD, Geertruy Kronnie, PhD

Blood (2011) 118 (21): 2454.

https://doi.org/10.1182/blood.V118.21.2454.2454

Published: 2011

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Single Cell Clones Derived from a Patient's AML Xenograft Display Genetic and Functional Heterogeneity

Generation, Characterization and Pre-Clinical Drug Evaluation of Patient-Derived Xenograft Models of Pediatric Down Syndrome AML

Angioimmunoblastic T-Cell Lymphoma: Molecular Characterization of Clonal T and B-Cells and a Patient Derived Xenograft Model of Coexisting T and B-Cell Proliferations

Metabolism of Acute Myeloid Leukemia Cell Lines Alters with Passage in 2D Culture and Remains Stable in 3D

Microrna-126 Levels Modulate B-ALL Aggressiveness but Require Tight Regulation to Guarantee Disease Maintenance

Generation and Application of T-Cell Lymphoma Patient Derived Tumor Xenograft Models

AML Differentially Alters Fate and Function of Mesenchymal Stem- and Osteolineage Cells in the Leukemic Niche

VEGFA- a New Therapeutic Target in CNS Leukemia

A Pharmacologically Reversible Epigenomic Signature of Relapse and Chemotherapy Resistance in Anaplastic Large Cell Lymphoma

Clinical and Biological Features Associated with Engraftment of Acute Myeloid Leukemia Patient-Derived Xenografts

B and T-Cell Lymphoma Patient-Derived Xenografts Recapitulate Aspects of Disease Biology and Progression and Represent Novel Tools for Preclinical Drug Development

Lineage Switch As a Relapse Mechanism of Pre-B Acute Lymphoblastic Leukemia Following CD19 CAR

Development and Analysis of Novel Intravascular Large B-Cell Lymphoma NOD/Shi- Scid IL2Rγ null Mouse Xenograft Model

Microenvironmental Contribution to Dysfunctional Hematopoiesis in a Murine Model of Myelodysplastic Syndrome

Identification of Cmtm Family Proteins As Tumor Suppressor and Membrane Regulator in B Cell Precursor Acute Lymphoblastic Leukemia

Novel Intracranial Xenografts Of CNS Lymphoma Implicate a Role For Cereblon As a Mediator Of Lenalidomide Efficacy

Inhibition Of Telomerase Is a Novel and Effective Therapy In MLL-Rearranged Acute Myeloid Leukemia (AML)

Comparative Analysis of SSEA4 + and SSEA4 − Mesenchymal Stem Cells Derived From Wharton's Jelly of Umbilical Cord

Influence of Different Genetic Alterations On the Engraftment Capacity and Serial Transplantation Efficiency of AML Patient-Derived Bone Marrow and Peripheral Blood Cells in NSG Mice

Evolution of Sub-Clones with KRAS Mutations In Pediatric Patients with MLL-AF4 Rearrangements

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