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Journal Articles

Identification of Genetic Vulnerabilities and Synthetic-Lethal Targets in NSD2-High Multiple Myeloma

Amin Sobh, PhD, Charlotte Kaestner, Alberto Riva, PhD, Jonathan D. Licht, MD

Blood (2019) 134 (Supplement_1): 3757.

https://doi.org/10.1182/blood-2019-125951

Published: 2019

Journal Articles

Identification of Beta-Catenin As a Novel Ubiquitin-Regulated Target of Combined Flβ3/Syk- and Proteasome Inhibitors for Interruption of LSC Signaling in Poor-Risk AML

Sravanti Rangaraju, MBBS, Silvia Marino, PhD, Daniela Nicoleta Petrusca, PhD, Larry D Cripe, MD, Katie J Sargent, RN, G. David Roodman, MD PhD, Hamid Sayar, MD MSc, Baskar Ramdas, PhD, Lakshmi Reddy Palam, PhD, Rajasubramaniam Shanmugam, PhD, Adriana Rogozea, Heiko Konig, MD PhD, Reuben Kapur, PhD, H. Scott Boswell, MD

Blood (2018) 132 (Supplement 1): 3949.

https://doi.org/10.1182/blood-2018-99-111181

Published: 2018

Journal Articles

Microrna-126 Levels Modulate B-ALL Aggressiveness but Require Tight Regulation to Guarantee Disease Maintenance

Carolina Caserta, Silvia Nucera, MD, Matteo Maria Naldini, Nadia Foligno, Giacomo Desantis, PhD, Fabio Ciceri, MD, Davide Cittaro, PhD, Bernhard Gentner, MD

Blood (2018) 132 (Supplement 1): 2834.

https://doi.org/10.1182/blood-2018-99-115101

Published: 2018

Journal Articles

Attenuated Protein Synthesis Drives the Hematopoietic Defects in Shwachman-Diamond Syndrome

Pekka Jaako, PhD, Chi C Wong, PhD MD, David Adams, PhD, Alan J. Warren, PhD FRCP, FRCPath

Blood (2017) 130 (Supplement 1): 876.

https://doi.org/10.1182/blood.V130.Suppl_1.876.876

Published: 2017

Journal Articles

HIF1A Is a Critical Downstream Mediator for Hemophagocytic Lymphohistiocytosis

Blood (2017) 130 (Supplement 1): 3565.

https://doi.org/10.1182/blood.V130.Suppl_1.3565.3565

Published: 2017

Journal Articles

CITED2 Affects Leukemic Cell Survival By Interfering with p53 Activation

Katharina Mattes, MSc, Gerbrig Berger, BSc, Marjan Geugien, MSc, Joost H.A. Martens, Edo Vellenga, MD PhD, Hein Schepers, PhD

Blood (2016) 128 (22): 1542.

https://doi.org/10.1182/blood.V128.22.1542.1542

Published: 2016

Journal Articles

The Methylation-Sensitive Enhancer Derare Maintains Hematopoietic Stem Cells through Regulation of Hoxb Cluster

Pengxu Qian, PhD, Bony De Kumar, PhD, Youngwook Ahn, PhD, Christof Nolte, PhD, Ariel Paulson, PhD, Xi C He, MD, Zhenrui Li, John M. Perry, PhD, Meng Zhao, PhD, Fang Tao, Robb Krumlauf, PhD, Linheng Li, PhD

Blood (2016) 128 (22): 725.

https://doi.org/10.1182/blood.V128.22.725.725

Published: 2016

Journal Articles

Characterization of Genomic Rearrangements Involving CIITA and SOCS1 U sing Targeted Capture Sequencing of Archival Tissue Specimens

Anja Mottok, Lauren Chong, MSc, Susana Ben-Neriah, Bruce Woolcock, MSc, Yongjun Zhao, PhD, Marco A Marra, PhD, David W. Scott, Randy D. Gascoyne, Andrew J. Mungall, Christian Steidl

Blood (2016) 128 (22): 2925.

https://doi.org/10.1182/blood.V128.22.2925.2925

Published: 2016

Journal Articles

Low Expression of the CIITA Gene Predicts Poor Outcome in Diffuse Large B-Cell Lymphoma

Matias Autio, MS, Kirsi Jäntti, PhD, Alejandra Cervera, MSc, Sampsa Hautaniemi, Professor, Sirpa Leppä, MD PhD

Blood (2016) 128 (22): 2948.

https://doi.org/10.1182/blood.V128.22.2948.2948

Published: 2016

Journal Articles

ASH1L: A Novel Beta-Globin Gene Regulator in Humans?

Amandine Breton, PhD, Laura Sonzogni, PhD, Andria Theodorou, PhD, Suleyman Aktuna, PhD, Stephan Menzel, PhD, Frank Grosveld, PhD, Sjaak Philipsen, PhD, Swee Lay Thein, MD DSc

Blood (2015) 126 (23): 641.

https://doi.org/10.1182/blood.V126.23.641.641

Published: 2015

Journal Articles

A Phase I/II Trial of Vorinostat (SAHA) in Combination with Rituximab-CHOP in Patients with Newly Diagnosed Advanced Stage Diffuse Large B-Cell Lymphoma (DLBCL): SWOG S0806

Daniel O. Persky, MD, Hongli Li, PhD, Lisa M. Rimsza, MD, Paul M. Barr, MD, Leslie L. Popplewell, MD, Charles L. Bane, MD, Ann Von Gehr, MD, Michael Leblanc, PhD, Richard I. Fisher, MD, Sonali M. Smith, MD, Jonathan W. Friedberg, MD MMSc

Blood (2015) 126 (23): 3931.

https://doi.org/10.1182/blood.V126.23.3931.3931

Published: 2015

Journal Articles

Regulation of IgD Expression and Its Role in B Cell Transformation

Yu Qian, PhD, Qiang Ke, PhD, Zhe Wang, PhD, Baochun Zhang, MDPhD

Blood (2015) 126 (23): 2230.

https://doi.org/10.1182/blood.V126.23.2230.2230

Published: 2015

Journal Articles

Genetic Alterations of the MHC Class II Transactivator CIITA Are Frequent in Primary Mediastinal Large B-Cell Lymphoma and Associated with Diminished MHC Class II Expression

Anja Mottok, MD, Bruce W. Woolcock, MSc, Fong Chun Chan, MSc, Adele Telenius, MSc, Elizabeth A. Chavez, Cg R.T, Merrill Boyle, B.Sc., Susana Ben-Neriah, MSc, Lisa M. Rimsza, MD, Reiner Siebert, MD, Randy D. Gascoyne, MD, Christian Steidl, MD

Blood (2014) 124 (21): 3040.

https://doi.org/10.1182/blood.V124.21.3040.3040

Published: 2014

Journal Articles

Assessment of HbF QTLs Affecting Disease Severity and Genetic Analysis in Patients Homozygous for Codon 8 (–AA) β 0 -Thalassemia Mutation

Zhihua Jiang, PhD, Shengwen Huang, MD PhD, Hong Yuan Luo, MB, PhD, Nejat Akar, MD, A.Nazli Basak, MD, Nasir Al-Allawi, MD PhD, Sule Unal, MD, Fatma Gumruk, MDProf, Lance Davis, MD, Tasha Morrison, MPH,BA, Andrew Campbell, MD, Patrick G. Gallagher, MD, Bernard G Forget, MD, Martin H. Steinberg, MD, David H.K. Chui, MD

Blood (2014) 124 (21): 2690.

https://doi.org/10.1182/blood.V124.21.2690.2690

Published: 2014

Journal Articles

Micro RNA Profiling to Identify Regulator of Fetal Hemoglobin Expression in Sickle Cell Disease

Biaoru Li, PhD, Christina M. Torres, BS, Mayuko Takezaki, MS, Cindy Neunert, MD MSCS, Abdullah Kutlar, MD, Betty S. Pace, MD

Blood (2014) 124 (21): 49.

https://doi.org/10.1182/blood.V124.21.49.49

Published: 2014

Journal Articles

CITED2 Facilitates Apoptosis Induced By Histone Deacetylase Inhibitor SAHA In Human Pediatric Pre-B Acute Lymphoblastic Leukemia Cells

Jinwei Du, PhD, Shigemi Matsuyama, PhD, Yu-Chung Yang, PhD

Blood (2013) 122 (21): 2913.

https://doi.org/10.1182/blood.V122.21.2913.2913

Published: 2013

Journal Articles

Tfeb Functions As a Tumor Suppressor That Harnesses Myc-Induced Lymphomagenesis By Provoking Senescence and Metabolic Catastrophe

Franz X Schaub, Mohammad Fallahi, Weimin Li, Stephanie K Demetriou, Chunying Yang, Antonio L Amelio, John L Cleveland

Blood (2013) 122 (21): 3784.

https://doi.org/10.1182/blood.V122.21.3784.3784

Published: 2013

Journal Articles

A Novel Conditional Mouse Model For MLL-ENL Induced Acute Leukemia

Vaia Stavropoulou, PhD, Sabine Juge, Alexander Tzankov, MD, PhD, Michael Kyba, PhD, Antoine H.F.M. Peters, PhD, Juerg Schwaller, MD

Blood (2013) 122 (21): 1277.

https://doi.org/10.1182/blood.V122.21.1277.1277

Published: 2013

Journal Articles

Talen-Mediated Knock Outs Of Cis and Trans Elements Potentially Involved In Globin Gene Switching

Patrick A Navas, PHD, Yongqi Yan, PhD, Minerva E Sanchez, BS, Ericka M Johnson, BS, George Stamatoyannopoulos, MD, DSci

Blood (2013) 122 (21): 436.

https://doi.org/10.1182/blood.V122.21.436.436

Published: 2013

Journal Articles

Mutant U2AF1 Expression Alters Hematopoiesis In Transgenic Mice

Cara Lunn Shirai, Ph.D., Justin Tibbitts, MS MBA, Jin Shao, Matthew Ndonwi, PhD, James N Ley, Sanghyun Kim, Manorama Tripathi, PhD, Theresa Okeyo-Owuor, Timothy A. Graubert, MD, Matthew J. Walter, MD

Blood (2013) 122 (21): 99.

https://doi.org/10.1182/blood.V122.21.99.99

Published: 2013

NARROW

Identification of Genetic Vulnerabilities and Synthetic-Lethal Targets in NSD2-High Multiple Myeloma

Identification of Beta-Catenin As a Novel Ubiquitin-Regulated Target of Combined Flβ3/Syk- and Proteasome Inhibitors for Interruption of LSC Signaling in Poor-Risk AML

Microrna-126 Levels Modulate B-ALL Aggressiveness but Require Tight Regulation to Guarantee Disease Maintenance

Attenuated Protein Synthesis Drives the Hematopoietic Defects in Shwachman-Diamond Syndrome

HIF1A Is a Critical Downstream Mediator for Hemophagocytic Lymphohistiocytosis

CITED2 Affects Leukemic Cell Survival By Interfering with p53 Activation

The Methylation-Sensitive Enhancer Derare Maintains Hematopoietic Stem Cells through Regulation of Hoxb Cluster

Characterization of Genomic Rearrangements Involving CIITA and SOCS1 U sing Targeted Capture Sequencing of Archival Tissue Specimens

Low Expression of the CIITA Gene Predicts Poor Outcome in Diffuse Large B-Cell Lymphoma

ASH1L: A Novel Beta-Globin Gene Regulator in Humans?

A Phase I/II Trial of Vorinostat (SAHA) in Combination with Rituximab-CHOP in Patients with Newly Diagnosed Advanced Stage Diffuse Large B-Cell Lymphoma (DLBCL): SWOG S0806

Regulation of IgD Expression and Its Role in B Cell Transformation

Genetic Alterations of the MHC Class II Transactivator CIITA Are Frequent in Primary Mediastinal Large B-Cell Lymphoma and Associated with Diminished MHC Class II Expression

Assessment of HbF QTLs Affecting Disease Severity and Genetic Analysis in Patients Homozygous for Codon 8 (–AA) β 0 -Thalassemia Mutation

Micro RNA Profiling to Identify Regulator of Fetal Hemoglobin Expression in Sickle Cell Disease

CITED2 Facilitates Apoptosis Induced By Histone Deacetylase Inhibitor SAHA In Human Pediatric Pre-B Acute Lymphoblastic Leukemia Cells

Tfeb Functions As a Tumor Suppressor That Harnesses Myc-Induced Lymphomagenesis By Provoking Senescence and Metabolic Catastrophe

A Novel Conditional Mouse Model For MLL-ENL Induced Acute Leukemia

Talen-Mediated Knock Outs Of Cis and Trans Elements Potentially Involved In Globin Gene Switching

Mutant U2AF1 Expression Alters Hematopoiesis In Transgenic Mice

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American Society of Hematology

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