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Journal Articles

Recurrent Amplification of Chromosome 7 in Murine AML with Dnmt3a R878H and Npm1 cA Mutations Identifies Gab2 As a Possible Therapeutic Target in AML

Free
Michael H. Kramer, Stephanie N Richardson, Yang Li, Tiankai Yin, Nichole Helton, Daniel George, Michelle Cai, Sai Mukund Ramakrishnan, Christopher A Miller, Timothy J Ley
Journal: Blood
Blood (2024) 144 (Supplement 1): 1333.
https://doi.org/10.1182/blood-2024-199837
Published: 2024
Journal Articles

Churn, Churn Churn! a Mixed Methods Analysis of Young Adult Leukemia and Lymphoma Survivors' Experience Navigating the Insurance Landscape in a Post Affordable Care Act Era

Free
Daniel J. Zheng, Rachel Murphy-Banks, Angie Mae Rodday, Qingyan Xiang, Nadine Linendoll, Melissa P Beauchemin, Timothy J. D. Ohlsen, Emma Fleisher, Kimberly A. Miller, David R. Freyer, Howland E. Crosswell, Randall Chan, Michael E. Roth, Susan K. Parsons
Journal: Blood
Blood (2024) 144 (Supplement 1): 785.
https://doi.org/10.1182/blood-2024-204928
Published: 2024
Journal Articles

Six-Month Resistance Training Interventions Are Associated with Improvements in Fatigue and Pain in Multiple Myeloma Patients

Free
Janine M. Joseph, Michaela Hillengass, Bryan J. Wittmeyer, Carolyn A. Miller, Hillary M. Jacobson, Kirsten B. Moysich, Rikki A. Cannioto, Jens Hillengass
Journal: Blood
Blood (2024) 144 (Supplement 1): 705.
https://doi.org/10.1182/blood-2024-211391
Published: 2024
Journal Articles

VISTA As a Mediator of Immune Suppression in AML Initiated By DNMT3A and NPM1 mutations

Free
Tiankai Yin, Michael H. Kramer, Michael Bern, Nichole Helton, Daniel George, Mieke Hoock, Sai Mukund Ramakrishnan, Christopher A Miller, Timothy J Ley
Journal: Blood
Blood (2024) 144 (Supplement 1): 4100.
https://doi.org/10.1182/blood-2024-206063
Published: 2024
Journal Articles

Reduced CBFB Expression Causes Compensatory Upregulation of RUNX1 Expression, Defining a Feedback Loop That May be Relevant for AML Pathogenesis

Free
Ryan B. Day, Sai Mukund Ramakrishnan, Christopher A Miller, Timothy J Ley
Journal: Blood
Blood (2024) 144 (Supplement 1): 4107.
https://doi.org/10.1182/blood-2024-207713
Published: 2024
Journal Articles

Overexpression of the Signaling Integrator Gab2 Accelerates AML Development in Mice with Dnmt3a R878H and Npm1 cA Mutations

Free
Michael H. Kramer, Stephanie Richardson, Yang Li, Nichole Helton, Daniel George, Michelle Cai, Sai Mukund Ramakrishnan, Christopher A Miller, Timothy J Ley
Journal: Blood
Blood (2023) 142 (Supplement 1): 2752.
https://doi.org/10.1182/blood-2023-175053
Published: 2023
Journal Articles

Mechanisms of PML::Rara and GATA2 Protein Interactions in Hematopoietic Cells

Free
Casey Katerndahl, Olivia Rogers, Nichole Helton, Sai Mukund Ramakrishnan, Christopher A Miller, Ziheng Xu, Sridhar N Srivatsan, Timothy J Ley
Journal: Blood
Blood (2023) 142 (Supplement 1): 2758.
https://doi.org/10.1182/blood-2023-181291
Published: 2023
Journal Articles

Reduced Subclone Diversity in Clonal Cytopenia of Undetermined Significance Compared to Myelodysplastic Syndrome

Free
Monique Chavez, Sridhar N Srivatsan, Christopher A Miller, Andrew J. Menssen, Ajay Khanna, Jin Shao, Catrina Fronick, Robert Fulton, Sharon E Heath, Constantine Logothetis, Tasha Burton, Victoria Donaldson, Claudia Cabrera, Raya Saba, Kiran R. Vij, Eric J. Duncavage, Meagan Jacoby, Matthew J. Walter
Journal: Blood
Blood (2023) 142 (Supplement 1): 2696.
https://doi.org/10.1182/blood-2023-189591
Published: 2023
Journal Articles

Rapid and Accurate Remethylation of Dnmt3a Deficient Hematopoietic Cells with Restoration of DNMT3A Activity

Free
Yang Li, Haley Abel, Michelle Cai, Taylor Lavalle, Tiankai Yin, Nichole Helton, Amanda Smith, Christopher A Miller, Timothy J Ley
Journal: Blood
Blood (2023) 142 (Supplement 1): 4124.
https://doi.org/10.1182/blood-2023-180255
Published: 2023
Journal Articles

ITK Inhibitor Induces Dose-Dependent Th1 Skewing in Normal T Cells and Is Active in Refractory T Cell Lymphomas

Free
Yuqin Song, Ning Ding, Dok Hyun Yoon, John C. Reneau, Ryan A. Wilcox, Won Seog Kim, Youn H. Kim, Michael S. Khodadoust, Tatyana A. Feldman, Costas K. Yannakou, Pratyush Giri, Jonathan E Brammer, Lih-Yun Hsu, Hongwei Yuan, Erik Verner, Suresh Mahabhashyam, Richard A. Miller
Journal: Blood
Blood (2022) 140 (Supplement 1): 8857–8859.
https://doi.org/10.1182/blood-2022-159177
Published: 2022
Journal Articles

Nucleolar Stress Plays a Key Role in the Pathogenesis of T Cell Acute Lymphoblastic Leukemia

Free
Joseph R. Krambs, Kimberly B. Johansson, Isabelle Genter, Sai Mukund Ramakrishnan, Christopher A Miller, Daniel C. Link
Journal: Blood
Blood (2022) 140 (Supplement 1): 5891–5892.
https://doi.org/10.1182/blood-2022-158717
Published: 2022
Journal Articles

A Comprehensive Reassessment of the Direct DNA Binding Sites of PML-Rara within the Genomes of Primary Hematopoietic Progenitor Cells, and Their Effects on Chromatin Structure and Gene Expression

Free
Casey D.S. Katerndahl, Olivia R.S. Rogers, Sai Mukund Ramakrishnan, Christopher A Miller, Nichole M Helton, Mieke Hoock, Timothy J Ley
Journal: Blood
Blood (2022) 140 (Supplement 1): 5858–5859.
https://doi.org/10.1182/blood-2022-167204
Published: 2022
Journal Articles

Re-Sensitization of Allogeneic T Cell Resistant Murine AML with Pegylated IFN-Gamma

Free
Ezhilarasi Chendamarai, Julie K. Ritchey, Leah Gehrs, Michael P. Rettig, Sai Mukund Ramakrishnan, Christopher A Miller, George Cox, Lana Anderson, Timothy J Ley, John F. DiPersio
Journal: Blood
Blood (2022) 140 (Supplement 1): 7345–7346.
https://doi.org/10.1182/blood-2022-167415
Published: 2022
Journal Articles

Proteomic and phosphoproteomic landscapes of acute myeloid leukemia

Open Access
Michael H. Kramer, Qiang Zhang, Robert Sprung, Ryan B. Day, Petra Erdmann-Gilmore, Yang Li, Ziheng Xu, Nichole M. Helton, Daniel R. George, Yiling Mi, Peter Westervelt, Jacqueline E. Payton, Sai M. Ramakrishnan, Christopher A. Miller, Daniel C. Link, John F. DiPersio, Matthew J. Walter, R. Reid Townsend, Timothy J. Ley
Journal: Blood
Blood (2022) 140 (13): 1533–1548.
https://doi.org/10.1182/blood.2022016033
Published: 2022
Includes: Supplemental data
Journal Articles

DNMT3A overgrowth syndrome is associated with the development of hematopoietic malignancies in children and young adults

Free
Clinical Trials & Observations
Margaret A. Ferris, Amanda M. Smith, Sharon E. Heath, Eric J. Duncavage, Matthew Oberley, David Freyer, Robert Wynn, Sofia Douzgou, John M. Maris, Anne F. Reilly, Melinda D. Wu, Florence Choo, Roel B. Fiets, Saskia Koene, David H. Spencer, Christopher A. Miller, Marwan Shinawi, Timothy J. Ley
Journal: Blood
Blood (2022) 139 (3): 461–464.
https://doi.org/10.1182/blood.2021014052
Published: 2022
Includes: Supplemental data
Journal Articles

Analysis of the Proteomes of Primary, De Novo Acute Myeloid Leukemia Cells from Adults

Free
Michael H Kramer, Qiang Zhang, Robert W. Sprung, Petra Erdmann-Gilmore, Daniel R George, Nichole M Helton, Sharon E Heath, Jacqueline E. Payton, Peter Westervelt, Christopher A Miller, Matthew J. Walter, Daniel C. Link, John F. DiPersio, R Reid Townsend, Timothy J Ley
Journal: Blood
Blood (2021) 138 (Supplement 1): 3427.
https://doi.org/10.1182/blood-2021-148819
Published: 2021
Journal Articles

Dnmt3a Inactivation Leads to Slow DNA Methylation Loss in Murine Hematopoietic Cells In Vivo

Free
Amanda M Smith, Angela Maria Verdoni, Shamika Ketkar, Elizabeth Leight, David Y Chen, Sai Mukund Ramakrishnan, Christopher A Miller, Haley J Abel, Timothy J Ley
Journal: Blood
Blood (2021) 138 (Supplement 1): 1087.
https://doi.org/10.1182/blood-2021-150558
Published: 2021
Journal Articles

Adverse Outcomes in Acute Myeloid Leukemia Are Associated with Tumor Cell-Mediated Immunosuppression

Free
Francesca Ferraro, Christopher A Miller, Keegan A Christensen, Nichole M Helton, Michelle O'Laughlin, Robert Fulton, Jessica Kohlschmidt, Ann-Kathrin Eisfeld, Bloomfield Clara, Sai Mukund Ramakrishnan, Lukas D Wartman, John Welch, Matthew Christopher, Sharon E Heath, Peter Westervelt, Jack D Baty, Jacqueline E. Payton, Michael Retting, Daniel C. Link, Matthew J. Walter, John F. DiPersio, Ryan Day, Geoffrey L. Uy, Matthew Schuelke, David H Spencer, Timothy J Ley
Journal: Blood
Blood (2021) 138 (Supplement 1): 800.
https://doi.org/10.1182/blood-2021-148645
Published: 2021
Journal Articles

Tumor suppressor function of Gata2 in acute promyelocytic leukemia

Free
Casey D. S. Katerndahl, Olivia R. S. Rogers, Ryan B. Day, Michelle A. Cai, Timothy P. Rooney, Nichole M. Helton, Mieke Hoock, Sai Mukund Ramakrishnan, Sridhar Nonavinkere Srivatsan, Lukas D. Wartman, Christopher A. Miller, Timothy J. Ley
Journal: Blood
Blood (2021) 138 (13): 1148–1161.
https://doi.org/10.1182/blood.2021011758
Published: 2021
Includes: Supplemental data
Journal Articles

Signaling Gene Mutations Are Characterized By Diverse Patterns of Expansion and Contraction during Progression from MDS to Secondary AML

Free
Andrew J Menssen, BA, Ajay Khanna, Christopher A Miller, PhD, Gue Su Chang, PhD, Jin J Shao, Sridhar Nonavinkere Srivatsan, MS, Joshua Robinson, Michelle O'Laughlin, Catrina Fronick, BS, Robert Fulton, MS, Kimberly J Brendel, Sharon E Heath, Peter Westervelt, MDPhD, John F. DiPersio, MD PhD, Daniel C. Link, MD, Meagan A. Jacoby, Eric Duncavage, MD, Timothy J Ley, MD, Matthew J. Walter, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
https://doi.org/10.1182/blood-2020-140394
Published: 2020