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Alexandra Lenard
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Journal Articles

GATA2 links stemness to chemotherapy resistance in acute myeloid leukemia.

Fatemeh Alikarami, Hongbo M Xie, Simone S Riedel, Haley Goodrow, Declan Raymond Barrett, Leila Mahdavi, Alexandra Lenard, Changya Chen, Taylor Yamauchi, Etienne Danis, Zhendong Cao, Vu Le-Huy Tran, Mabel Minji Jung, Yapeng Li, Hua Huang, Junwei Shi, Kai Tan, David Trent Teachey, Emery H Bresnick, Tobias Neff, Kathrin Maria Bernt
Journal: Blood
Blood blood.2024025761.
https://doi.org/10.1182/blood.2024025761
Published: 2025
Includes: Supplemental data
Journal Articles

Aberrant Stemness Transcription Signature Unveils a Mechanism of Chemotherapy Resistance through Blunting p53-Mediated Response in Acute Myeloid Leukemia

Fatemeh Alikarami, Hongbo Xie, Simone Stefanie Riedel, Haley Goodrow, Declan Barrett, Leila Mahdavi, Alexandra Lenard, Changya Chen, Taylor Yamauchi, Etienne Danis, Zhendong Cao, Vu L. Tran, Mabel M. Jung, Yapeng Li, Hua Huang, Junwei Shi, Kai Tan, David T. Teachey, Emery H. Bresnick, Tobias Neff, Kathrin M. Bernt
Journal: Blood
Blood (2024) 144 (Supplement 1): 725.
https://doi.org/10.1182/blood-2024-199215
Published: 2024
Journal Articles

Transcriptomic without Clinical Response to Menin Inhibition As a Mechanism of Upfront Resistance in Samples from Mutliply Relapsed Patients with KMT2A-Rearranged Leukemia

Leila Mahdavi, Haley Goodrow, Hongbo Xie, Alexandra Lenard, Fatemeh Alikarami, Simone Stefanie Riedel, Sarah K. Tasian, Gerald Wertheim, Sarah Skuli, Martin Carroll, Jerry McGeehan, Kathrin M. Bernt
Journal: Blood
Blood (2023) 142 (Supplement 1): 4166.
https://doi.org/10.1182/blood-2023-180967
Published: 2023
Journal Articles

SWI/SNF Dysregulation through a Prion-like Domain Causes AML

Simone S Riedel, PhD, Alexandra Lenard, BS, Kevin Nestler, BS, Congcong Lu, PhD, Hongbo Xie, PhD, Benjamin A Garcia, PhD, Kathrin M. Bernt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2512.
https://doi.org/10.1182/blood-2019-129280
Published: 2019