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Journal Articles

Heterodimerization of CSF3R Splice Variants and Mutants Alter Receptor Function

Sara L. Seegers, Amanda Lance, Steven I. Park, Belinda R. Avalos, Lawrence J Druhan

Blood (2022) 140 (Supplement 1): 5465–5466.

https://doi.org/10.1182/blood-2022-170480

Published: 2022

Journal Articles

CSF3R Splicing Regulates Granulopoiesis Via Splice Variant Specific Responses to G-CSF

Amanda Lance, Rajeswaran Mani, Sara L. Seegers, Belinda R Avalos, Lawrence J Druhan

Blood (2021) 138 (Supplement 1): 3130.

https://doi.org/10.1182/blood-2021-154322

Published: 2021

Journal Articles

Hereditary Chronic Neutrophilic Leukemia in a Four Generation Family without Transformation to Acute Leukemia

Zane Chiad, Amanda Lance, Sara L. Seegers, Sarah-Catherine Paschall, Kendra Drummond, Nury M Steuerwald, Peter M. Voorhees, Belinda Avalos, Lawrence J Druhan

Blood (2021) 138 (Supplement 1): 3594.

https://doi.org/10.1182/blood-2021-153899

Published: 2021

Journal Articles

Complex CSF3R Protein Isoform Interactions Dictate Cytokine Responsiveness

Sara L. Seegers, M.S., Amanda Lance, MS, Lawrence J Druhan, PhD, Belinda R Avalos, MD

Blood (2020) 136 (Supplement 1): 35.

https://doi.org/10.1182/blood-2020-143107

Published: 2020

Journal Articles

Alternative Splicing and Intronic Polyadenylation Post-Transcriptionally Regulate CSF3R Via a Cryptic Exon

Lawrence J Druhan, PhD, Amanda Lance, MS, Alicia Hamilton, Nury M Steuerwald, PhD, Elise Tjaden, Belinda R Avalos, MD

Blood (2019) 134 (Supplement_1): 2462.

https://doi.org/10.1182/blood-2019-129102

Published: 2019

Journal Articles

New Germline Syndrome Discovery: Heterozygous CSF3R Mutations May Predispose to Myeloid and Lymphoid Malignancies

Amy M Trottier, MDBSc,MSc, Ira L Kraft, MD, Lawrence J Druhan, PhD, Amanda Lance, MS, Belinda R Avalos, MD, Lucy A Godley, MD PhD

Blood (2019) 134 (Supplement_1): 2543.

https://doi.org/10.1182/blood-2019-129492

Published: 2019

Journal Articles

Mutations in SRSF2 Alter CSF3R Splicing in AML and Increase Expression of the V3 Variant Relative to V1

Lawrence J Druhan, PhD, Amanda Lance, MS, Carol G. Vestal, Andrea Price, Matthew Smith, Alicia Hamilton, Nury M Steuerwald, PhD, Belinda Rene Avalos, MD

Blood (2018) 132 (Supplement 1): 1106.

https://doi.org/10.1182/blood-2018-99-120000

Published: 2018

Journal Articles

Aberrant Trafficking and Signal Propagation By the T618I CSF3R Mutant in Patients with Chronic Neutrophilic Leukemia

Lawrence J Druhan, PhD, Andrea Price, Amanda Lance, Alicia Hamilton, Judy Parsons, MT, Fei Guo, PhD, David M Foureau, PhD, Nury M Steuerwald, PhD, Belinda Rene Avalos, MD

Blood (2017) 130 (Supplement 1): 2941.

https://doi.org/10.1182/blood.V130.Suppl_1.2941.2941

Published: 2017

Journal Articles

A Novel Approach to Identify a Putative Leukemia Stem Cell Population in Acute Lymphocytic Leukemia (ALL) and Distinguish Philadelphia Chromosome-Positive ALL from Lymphoid Blast Crisis Chronic Myeloid Leukemia

Jonathan M. Gerber, MD, Lawrence J. Druhan, PhD, David Foureau, PhD, Elizabeth Jandrisevits, Amanda Lance, BS, Andrea E. Price, BS, Virginia Thurston, PhD, Jing Ai, MD PhD, Michael R. Grunwald, MD, Edward H. Lipford, MD, Belinda R. Avalos, MD

Blood (2016) 128 (22): 2912.

https://doi.org/10.1182/blood.V128.22.2912.2912

Published: 2016

Journal Articles

Chronic neutrophilic leukemia in a child with a CSF3R T618I germ line mutation

Lawrence J. Druhan, Daniel P. McMahon, Nury Steuerwald, Andrea E. Price, Amanda Lance, Jonathan M. Gerber, Belinda R. Avalos

Blood (2016) 128 (16): 2097–2099.

https://doi.org/10.1182/blood-2016-07-730606

Published: 2016

Journal Articles

Congenital Neutrophilia Arising from a T618I Germline Mutation in the CSF3R Gene

Daniel P McMahon, MD, Amanda Lance, BS, Andrea E. Price, BS, Jonathan M. Gerber, MD, Sarah A Baxter, PhD, Lawrence J Druhan, PhD, Nury M Steuerwald, PhD, Belinda R Avalos, MD

Blood (2015) 126 (23): 1623.

https://doi.org/10.1182/blood.V126.23.1623.1623

Published: 2015

Journal Articles

Neutrophils Promote Hematopoiesis Via a Novel Mechanism Involving Leucine Rich α-2 Glycoprotein (LRG)

Lawrence J Druhan, PhD, Shimena Li, Sarah A Baxter, PhD, Amanda Lance, Andrea E Price, Jacob T Emerson, Belinda R. Avalos, MD

Blood (2014) 124 (21): 2725.

https://doi.org/10.1182/blood.V124.21.2725.2725

Published: 2014

NARROW

Heterodimerization of CSF3R Splice Variants and Mutants Alter Receptor Function

CSF3R Splicing Regulates Granulopoiesis Via Splice Variant Specific Responses to G-CSF

Hereditary Chronic Neutrophilic Leukemia in a Four Generation Family without Transformation to Acute Leukemia

Complex CSF3R Protein Isoform Interactions Dictate Cytokine Responsiveness

Alternative Splicing and Intronic Polyadenylation Post-Transcriptionally Regulate CSF3R Via a Cryptic Exon

New Germline Syndrome Discovery: Heterozygous CSF3R Mutations May Predispose to Myeloid and Lymphoid Malignancies

Mutations in SRSF2 Alter CSF3R Splicing in AML and Increase Expression of the V3 Variant Relative to V1

Aberrant Trafficking and Signal Propagation By the T618I CSF3R Mutant in Patients with Chronic Neutrophilic Leukemia

A Novel Approach to Identify a Putative Leukemia Stem Cell Population in Acute Lymphocytic Leukemia (ALL) and Distinguish Philadelphia Chromosome-Positive ALL from Lymphoid Blast Crisis Chronic Myeloid Leukemia

Chronic neutrophilic leukemia in a child with a CSF3R T618I germ line mutation

Congenital Neutrophilia Arising from a T618I Germline Mutation in the CSF3R Gene

Neutrophils Promote Hematopoiesis Via a Novel Mechanism Involving Leucine Rich α-2 Glycoprotein (LRG)

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American Society of Hematology

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American Society of Hematology

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