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Journal Articles

MYC Pathway Upregulation Identified in Non-Responders to Hypomethylating Agents and Presents a Therapeutic Target in Acute Myeloid Leukemia

Brittany Knick Ragon, Margaret D. Templeton, Sara L. Seegers, Jenny Chen, Hsih-Te Yang, Thomas G. Knight, Jing Ai, Edward A. Copelan, Belinda Avalos, Nury M. Steuerwald, Jian Jin, Gang Greg Wang, Steven I. Park, Jai N. Patel, Michael R. Grunwald, Lawrence J. Druhan

Blood (2023) 142 (Supplement 1): 5741.

https://doi.org/10.1182/blood-2023-179318

Published: 2023

Journal Articles

Impact of Polymorphisms in Pharmacokinetic Genes on Tyrosine Kinase Inhibitor (TKI) Tolerability in Patients with Chronic Myeloid Leukemia (CML) or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)

Blood (2022) 140 (Supplement 1): 11530–11531.

https://doi.org/10.1182/blood-2022-166277

Published: 2022

Journal Articles

Clonal Hematopoiesis Prevalence and Mutational Spectrum in Patients with Plasma Cell Disorders at the Time of Diagnosis and Its Impact on Clinical Features, Cardiovascular Complications, and Survival

Srinivasa Reddy Sanikommu, Shebli Atrash, Myra Robinson, Nury M. Steuerwald, Kristen Cassetta, Hsih-Te Yang, Saad Usmani, Edward A. Copelan, Belinda R. Avalos, Lawrence J. Druhan

Blood (2022) 140 (Supplement 1): 11416–11417.

https://doi.org/10.1182/blood-2022-170887

Published: 2022

Journal Articles

Factors Predicting Efficacy and Toxicity of Post Transplantation Cyclophosphamide for Graft Versus Host Disease Prevention in Hematopoietic Cell Transplantation Recipients: Interim Data of an Ongoing Study

Aleksander L. Chojecki, Jai N. Patel, David M Foureau, James Symanowski, Xhevahire Begic, Michael Davis, Nury M Steuerwald, Sarah Norek, Srinivasa Reddy R. Sanikommu, Nilay A. Shah, Brittany Knick Ragon, Thomas G. Knight, Jing Ai, Michael R. Grunwald, Nilanjan Ghosh, Lawrence J Druhan, Belinda R. Avalos, Edward A. Copelan

Blood (2022) 140 (Supplement 1): 10534–10536.

https://doi.org/10.1182/blood-2022-160214

Published: 2022

Journal Articles

Impact of Race, Ethnicity, and Social Determinants of Heath on Outcomes for Acute Myeloid Leukemia Patients in a System with Specialized Nurse Navigation

Brittany Knick Ragon, Danielle Boselli, Rupali Bose, Stephanie Begley, Melissa Aguiar, Kris Blackley, Nilay A. Shah, Aleksander L. Chojecki, Srinivasa Reddy R. Sanikommu, Jing Ai, Lawrence J Druhan, Nury M Steuerwald, Jai N Patel, James T. Symanowski, Belinda R. Avalos, Edward A. Copelan, Derek Raghavan, Thomas G. Knight, Michael R. Grunwald

Blood (2022) 140 (Supplement 1): 10993–10995.

https://doi.org/10.1182/blood-2022-159179

Published: 2022

Journal Articles

Aurora Kinase Inhibition Overcomes Primary Venetoclax Failure and Leads to Synthetic Lethality in BCL2-Positive Lymphomas Via Upregulation of P53/P21/BAX Axis

Rajeswaran Mani, Samon Benrashid, Sarah E Teague, Scott C Jaros, Hsih-Te Yang, Lawrence J Druhan, David M Foureau, Nury M Steuerwald, Nilanjan Ghosh, Edward A. Copelan, Donald L. Durden, Belinda Avalos, Steven I. Park

Blood (2021) 138 (Supplement 1): 682.

https://doi.org/10.1182/blood-2021-146064

Published: 2021

Journal Articles

Hereditary Chronic Neutrophilic Leukemia in a Four Generation Family without Transformation to Acute Leukemia

Zane Chiad, Amanda Lance, Sara L. Seegers, Sarah-Catherine Paschall, Kendra Drummond, Nury M Steuerwald, Peter M. Voorhees, Belinda Avalos, Lawrence J Druhan

Blood (2021) 138 (Supplement 1): 3594.

https://doi.org/10.1182/blood-2021-153899

Published: 2021

Journal Articles

Alternative Splicing and Intronic Polyadenylation Post-Transcriptionally Regulate CSF3R Via a Cryptic Exon

Lawrence J Druhan, PhD, Amanda Lance, MS, Alicia Hamilton, Nury M Steuerwald, PhD, Elise Tjaden, Belinda R Avalos, MD

Blood (2019) 134 (Supplement_1): 2462.

https://doi.org/10.1182/blood-2019-129102

Published: 2019

Journal Articles

Molecular Characterization By Immune Profiling of Paired Blood and Bone Marrow in Multiple Myeloma and Its Precursor States

Manisha Bhutani, MD, David M. Foureau, PhD, Nury M Steuerwald, PhD, Sally Trufan, Fei Guo, PhD, Katherine Rigby, Elise Tjaden, Alicia Hamilton, Marina Leonidas, Aarin Berlin, Laura Johnson, Jordan Williams, Shebli Atrash, Ami P Ndiaye, NP, James Symanowski, PhD, Peter M. Voorhees, MD, Saad Z. Usmani, MD

Blood (2018) 132 (Supplement 1): 4461.

https://doi.org/10.1182/blood-2018-99-118281

Published: 2018

Journal Articles

Mutations in SRSF2 Alter CSF3R Splicing in AML and Increase Expression of the V3 Variant Relative to V1

Lawrence J Druhan, PhD, Amanda Lance, MS, Carol G. Vestal, Andrea Price, Matthew Smith, Alicia Hamilton, Nury M Steuerwald, PhD, Belinda Rene Avalos, MD

Blood (2018) 132 (Supplement 1): 1106.

https://doi.org/10.1182/blood-2018-99-120000

Published: 2018

Journal Articles

Busulfan Pharmacogenetics and Drug Exposure in Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation

Jai N Patel, PharmD, Issam Hamadeh, BS, Qing Zhang, PhD, Taylor Brown, BS, MS, Nury M Steuerwald, PhD, Alicia Hamilton, Lawrence J Druhan, PhD, Jiaxian He, MS, James T Symanowski, PhD, Mohammed J Hussain, MD, Jigar Trivedi, MSc, PharmD, Michael Richard Grunwald, MD, Nilanjan Ghosh, MD PhD, Belinda Rene Avalos, MD, Edward A Copelan, MD

Blood (2017) 130 (Supplement 1): 3215.

https://doi.org/10.1182/blood.V130.Suppl_1.3215.3215

Published: 2017

Journal Articles

Tacrolimus Pharmacogenetics and Steady State Drug Concentrations in Cancer Patients Undergoing Allogeneic Stem Cell Transplantation

Issam Hamadeh, BS, Qing Zhang, PhD, Nury M Steuerwald, PhD, Alicia Hamilton, Lawrence J Druhan, PhD, Yordanis Diez, PharmD, Stephanie Rusin, PharmD, Yimei Han, James Symanowski, PhD, Jigar Trivedi, MSc, PharmD, Michael Richard Grunwald, MD, Nilanjan Ghosh, MD PhD, Belinda Rene Avalos, MD, Edward A Copelan, MD, Jai N Patel, PharmD

Blood (2017) 130 (Supplement 1): 1939.

https://doi.org/10.1182/blood.V130.Suppl_1.1939.1939

Published: 2017

Journal Articles

Aberrant Trafficking and Signal Propagation By the T618I CSF3R Mutant in Patients with Chronic Neutrophilic Leukemia

Lawrence J Druhan, PhD, Andrea Price, Amanda Lance, Alicia Hamilton, Judy Parsons, MT, Fei Guo, PhD, David M Foureau, PhD, Nury M Steuerwald, PhD, Belinda Rene Avalos, MD

Blood (2017) 130 (Supplement 1): 2941.

https://doi.org/10.1182/blood.V130.Suppl_1.2941.2941

Published: 2017

Journal Articles

Peripheral Cellular Immunome Reveals Heterogeneity Spanning Myeloma Spectrum Diseases

Manisha Bhutani, MD, David M Foureau, PhD, Qing Zhang, PhD, Myra M Robinson, MSPH, Adina Wynn, Nury M Steuerwald, PhD, Lawrence J Druhan, PhD, Fei Guo, PhD, Katherine Rigby, Mitchell Turner, Reed Friend, MD, Shebli Atrash, Ami Ndiaye, Chelsea Sprouse, James T Symanowski, PhD, Belinda Rene Avalos, MD, Edward A Copelan, MD, Peter M. Voorhees, MD, Saad Z Usmani, MD

Blood (2017) 130 (Supplement 1): 3054.

https://doi.org/10.1182/blood.V130.Suppl_1.3054.3054

Published: 2017

Journal Articles

Effect of Immunomodulatory Drugs (IMiDs) on Immune Effectors after Autologous Stem Cell Transplantation (ASCT) in Multiple Myeloma

David M Foureau, PhD, Manisha Bhutani, MD, Qing Zhang, PhD, Myra M Robinson, MSPH, Adina Wynn, Nury M Steuerwald, PhD, Lawrence J Druhan, PhD, Fei Guo, PhD, Katherine Rigby, Mitchell Turner, Reed Friend, MD, Shebli Atrash, Chelsea Sprouse, Ami Ndiaye, James T Symanowski, PhD, Belinda Rene Avalos, MD, Edward A Copelan, MD, Peter M. Voorhees, MD, Saad Z Usmani, MD

Blood (2017) 130 (Supplement 1): 1817.

https://doi.org/10.1182/blood.V130.Suppl_1.1817.1817

Published: 2017

Journal Articles

CYP2C19 Genotype-Guided Dosing and Voriconazole Concentrations in Hematopoietic Stem Cell Transplant Patients (HSCT) Receiving Antifungal Prophylaxis

Jai N Patel, PharmD, Myra M Robinson, Issam Hamadeh, PharmD, Zainab Shahid, MD, James T Symanowski, PhD, Dragos Plesca, PharmD, PhD, Margaret Croom, PharmD, Jigar Trivedi, MSc, PharmD, Nury M. Steuerwald, PhD, Belinda R. Avalos, MD, Edward A. Copelan, MD FACP

Blood (2016) 128 (22): 3416.

https://doi.org/10.1182/blood.V128.22.3416.3416

Published: 2016

Journal Articles

Peripheral Immune Profile and Minimal Residual Disease (MRD) Burden Following Autologous Stem Cell Transplantation (ASCT) in Multiple Myeloma (MM)

David Foureau, PhD, Qing Zhang, PhD, Tammy D Cogdill, NP, Adina S Wynn, Nury M. Steuerwald, PhD, Lawrence J. Druhan, PhD, Fei Guo, Katherine Rigby, Kyle L Madden, BS, James T Symanowski, PhD, Belinda R. Avalos, MD, Edward A. Copelan, MD FACP, Saad Z Usmani, MD FACP, Manisha Bhutani, MD

Blood (2016) 128 (22): 378.

https://doi.org/10.1182/blood.V128.22.378.378

Published: 2016

Journal Articles

NF-κb / STAT3 Signaling Pathway Collaboration in Diffuse Large B-Cell Lymphoma (DLBCL) Cell-of-Origin (COO) Subtypes: Resolution of Myeloid Subversion By Standard Induction Chemotherapy

David Foureau, PhD, Qing Zhang, PhD, Lawrence J. Druhan, PhD, Nury M. Steuerwald, PhD, Fei Guo, Elizabeth Jandrisevits, Belinda R. Avalos, MD, Danyu Sun, MD PhD, Ryan Jacobs, MD, Nilanjan Ghosh, MD PhD

Blood (2016) 128 (22): 4133.

https://doi.org/10.1182/blood.V128.22.4133.4133

Published: 2016

Journal Articles

Cytokine Profiling of ABC-Subtype and GCB-Subtype Diffuse Large B Cell Lymphoma: Systemic Nfkb Activation and Impact on Myeloid-Derived Suppressor Cells Distribution

David Foureau, PhD, Lawrence J Druhan, PhD, Nury M Steuerwald, PhD, Sarah A Baxter, PhD, Omotayo O. Fasan, MBBS, MRCP, Belinda R Avalos, MD, Nilanjan Ghosh, MD PhD

Blood (2015) 126 (23): 2666.

https://doi.org/10.1182/blood.V126.23.2666.2666

Published: 2015

Journal Articles

Congenital Neutrophilia Arising from a T618I Germline Mutation in the CSF3R Gene

Daniel P McMahon, MD, Amanda Lance, BS, Andrea E. Price, BS, Jonathan M. Gerber, MD, Sarah A Baxter, PhD, Lawrence J Druhan, PhD, Nury M Steuerwald, PhD, Belinda R Avalos, MD

Blood (2015) 126 (23): 1623.

https://doi.org/10.1182/blood.V126.23.1623.1623

Published: 2015

NARROW

MYC Pathway Upregulation Identified in Non-Responders to Hypomethylating Agents and Presents a Therapeutic Target in Acute Myeloid Leukemia

Impact of Polymorphisms in Pharmacokinetic Genes on Tyrosine Kinase Inhibitor (TKI) Tolerability in Patients with Chronic Myeloid Leukemia (CML) or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)

Clonal Hematopoiesis Prevalence and Mutational Spectrum in Patients with Plasma Cell Disorders at the Time of Diagnosis and Its Impact on Clinical Features, Cardiovascular Complications, and Survival

Factors Predicting Efficacy and Toxicity of Post Transplantation Cyclophosphamide for Graft Versus Host Disease Prevention in Hematopoietic Cell Transplantation Recipients: Interim Data of an Ongoing Study

Impact of Race, Ethnicity, and Social Determinants of Heath on Outcomes for Acute Myeloid Leukemia Patients in a System with Specialized Nurse Navigation

Aurora Kinase Inhibition Overcomes Primary Venetoclax Failure and Leads to Synthetic Lethality in BCL2-Positive Lymphomas Via Upregulation of P53/P21/BAX Axis

Hereditary Chronic Neutrophilic Leukemia in a Four Generation Family without Transformation to Acute Leukemia

Alternative Splicing and Intronic Polyadenylation Post-Transcriptionally Regulate CSF3R Via a Cryptic Exon

Molecular Characterization By Immune Profiling of Paired Blood and Bone Marrow in Multiple Myeloma and Its Precursor States

Mutations in SRSF2 Alter CSF3R Splicing in AML and Increase Expression of the V3 Variant Relative to V1

Busulfan Pharmacogenetics and Drug Exposure in Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation

Tacrolimus Pharmacogenetics and Steady State Drug Concentrations in Cancer Patients Undergoing Allogeneic Stem Cell Transplantation

Aberrant Trafficking and Signal Propagation By the T618I CSF3R Mutant in Patients with Chronic Neutrophilic Leukemia

Peripheral Cellular Immunome Reveals Heterogeneity Spanning Myeloma Spectrum Diseases

Effect of Immunomodulatory Drugs (IMiDs) on Immune Effectors after Autologous Stem Cell Transplantation (ASCT) in Multiple Myeloma

CYP2C19 Genotype-Guided Dosing and Voriconazole Concentrations in Hematopoietic Stem Cell Transplant Patients (HSCT) Receiving Antifungal Prophylaxis

Peripheral Immune Profile and Minimal Residual Disease (MRD) Burden Following Autologous Stem Cell Transplantation (ASCT) in Multiple Myeloma (MM)

NF-κb / STAT3 Signaling Pathway Collaboration in Diffuse Large B-Cell Lymphoma (DLBCL) Cell-of-Origin (COO) Subtypes: Resolution of Myeloid Subversion By Standard Induction Chemotherapy

Cytokine Profiling of ABC-Subtype and GCB-Subtype Diffuse Large B Cell Lymphoma: Systemic Nfkb Activation and Impact on Myeloid-Derived Suppressor Cells Distribution

Congenital Neutrophilia Arising from a T618I Germline Mutation in the CSF3R Gene

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American Society of Hematology

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American Society of Hematology

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