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Journal Articles

Myeloid Derived Suppressor Cell Kinetics in Peripheral Blood Correlate with Efficacy and Toxicity of CAR T Cell Therapy in Relapsed or Refractory B Cell Lymphoma

David M Foureau, Hamid Ehsan, Fei Guo, Tahj Jones, Ryan W Jacobs, Bei Hu, Tamara K. Moyo, Yifan Pang, Steven I. Park, Lawrence J. Druhan, Ariel Bell, Nilanjan Ghosh

Blood (2023) 142 (Supplement 1): 1640.

https://doi.org/10.1182/blood-2023-187085

Published: 2023

Journal Articles

Socioeconomic Disadvantage Is Associated with Decreased Long-Term Survival in Adolescent and Young Adult Patients with Acute Lymphoblastic Leukemia

Allison Verbyla, Danielle Boselli, Brittany Knick Ragon, Jing Ai, Lawrence J. Druhan, Meng-Yun Lin, Michael R. Grunwald, Amresh Hanchate, Thomas G. Knight

Blood (2023) 142 (Supplement 1): 2391.

https://doi.org/10.1182/blood-2023-182299

Published: 2023

Journal Articles

Enhanced Support Services Including Nurse Navigation Mitigate Socioeconomic Disparities in the Treatment of Patients with Acute Lymphoblastic Leukemia

Thomas G. Knight, Danielle Boselli, Allison Verbyla, Jing Ai, Aleksander L. Chojecki, Nilay Shah, Yifan Pang, Lawrence J. Druhan, Edward A. Copelan, Michael R. Grunwald, Brittany Knick Ragon

Blood (2023) 142 (Supplement 1): 5078.

https://doi.org/10.1182/blood-2023-182371

Published: 2023

Journal Articles

MYC Pathway Upregulation Identified in Non-Responders to Hypomethylating Agents and Presents a Therapeutic Target in Acute Myeloid Leukemia

Brittany Knick Ragon, Margaret D. Templeton, Sara L. Seegers, Jenny Chen, Hsih-Te Yang, Thomas G. Knight, Jing Ai, Edward A. Copelan, Belinda Avalos, Nury M. Steuerwald, Jian Jin, Gang Greg Wang, Steven I. Park, Jai N. Patel, Michael R. Grunwald, Lawrence J. Druhan

Blood (2023) 142 (Supplement 1): 5741.

https://doi.org/10.1182/blood-2023-179318

Published: 2023

Journal Articles

Factors Predicting Efficacy and Toxicity of Post Transplantation Cyclophosphamide for Graft Versus Host Disease Prevention in Hematopoietic Cell Transplantation Recipients: Interim Data of an Ongoing Study

Aleksander L. Chojecki, Jai N. Patel, David M Foureau, James Symanowski, Xhevahire Begic, Michael Davis, Nury M Steuerwald, Sarah Norek, Srinivasa Reddy R. Sanikommu, Nilay A. Shah, Brittany Knick Ragon, Thomas G. Knight, Jing Ai, Michael R. Grunwald, Nilanjan Ghosh, Lawrence J Druhan, Belinda R. Avalos, Edward A. Copelan

Blood (2022) 140 (Supplement 1): 10534–10536.

https://doi.org/10.1182/blood-2022-160214

Published: 2022

Journal Articles

Clonal Hematopoiesis Prevalence and Mutational Spectrum in Patients with Plasma Cell Disorders at the Time of Diagnosis and Its Impact on Clinical Features, Cardiovascular Complications, and Survival

Srinivasa Reddy Sanikommu, Shebli Atrash, Myra Robinson, Nury M. Steuerwald, Kristen Cassetta, Hsih-Te Yang, Saad Usmani, Edward A. Copelan, Belinda R. Avalos, Lawrence J. Druhan

Blood (2022) 140 (Supplement 1): 11416–11417.

https://doi.org/10.1182/blood-2022-170887

Published: 2022

Journal Articles

Impact of Race, Ethnicity, and Social Determinants of Heath on Outcomes for Acute Myeloid Leukemia Patients in a System with Specialized Nurse Navigation

Brittany Knick Ragon, Danielle Boselli, Rupali Bose, Stephanie Begley, Melissa Aguiar, Kris Blackley, Nilay A. Shah, Aleksander L. Chojecki, Srinivasa Reddy R. Sanikommu, Jing Ai, Lawrence J Druhan, Nury M Steuerwald, Jai N Patel, James T. Symanowski, Belinda R. Avalos, Edward A. Copelan, Derek Raghavan, Thomas G. Knight, Michael R. Grunwald

Blood (2022) 140 (Supplement 1): 10993–10995.

https://doi.org/10.1182/blood-2022-159179

Published: 2022

Journal Articles

Heterodimerization of CSF3R Splice Variants and Mutants Alter Receptor Function

Sara L. Seegers, Amanda Lance, Steven I. Park, Belinda R. Avalos, Lawrence J Druhan

Blood (2022) 140 (Supplement 1): 5465–5466.

https://doi.org/10.1182/blood-2022-170480

Published: 2022

Journal Articles

Impact of Polymorphisms in Pharmacokinetic Genes on Tyrosine Kinase Inhibitor (TKI) Tolerability in Patients with Chronic Myeloid Leukemia (CML) or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)

Blood (2022) 140 (Supplement 1): 11530–11531.

https://doi.org/10.1182/blood-2022-166277

Published: 2022

Journal Articles

Aurora Kinase Inhibition Overcomes Primary Venetoclax Failure and Leads to Synthetic Lethality in BCL2-Positive Lymphomas Via Upregulation of P53/P21/BAX Axis

Rajeswaran Mani, Samon Benrashid, Sarah E Teague, Scott C Jaros, Hsih-Te Yang, Lawrence J Druhan, David M Foureau, Nury M Steuerwald, Nilanjan Ghosh, Edward A. Copelan, Donald L. Durden, Belinda Avalos, Steven I. Park

Blood (2021) 138 (Supplement 1): 682.

https://doi.org/10.1182/blood-2021-146064

Published: 2021

Journal Articles

Phase II Trial of Elotuzumab in Combination with Carfilzomib, Lenalidomide and Dexamethasone for the Treatment of Relapsed/Refractory Multiple Myeloma (RRMM) after One Prior Line of Therapy

Manisha Bhutani, Myra Robinson, Shebli Atrash, David M Foureau, Katherine Rigby, Reed Friend, Barry Paul, James T Symanowski, Lawrence J Druhan, Sarah Norek, Mallory Tucker, Mauricio Pineda-Roman, Peter M. Voorhees, Saad Z. Usmani

Blood (2021) 138 (Supplement 1): 2739.

https://doi.org/10.1182/blood-2021-148508

Published: 2021

Journal Articles

CSF3R Splicing Regulates Granulopoiesis Via Splice Variant Specific Responses to G-CSF

Amanda Lance, Rajeswaran Mani, Sara L. Seegers, Belinda R Avalos, Lawrence J Druhan

Blood (2021) 138 (Supplement 1): 3130.

https://doi.org/10.1182/blood-2021-154322

Published: 2021

Journal Articles

Hereditary Chronic Neutrophilic Leukemia in a Four Generation Family without Transformation to Acute Leukemia

Zane Chiad, Amanda Lance, Sara L. Seegers, Sarah-Catherine Paschall, Kendra Drummond, Nury M Steuerwald, Peter M. Voorhees, Belinda Avalos, Lawrence J Druhan

Blood (2021) 138 (Supplement 1): 3594.

https://doi.org/10.1182/blood-2021-153899

Published: 2021

Journal Articles

Central Memory T-Cell Differentiation Correlates with Depth of Response in Relapsed/Refractory Multiple Myeloma Patients Receiving Elotuzumab in Combination with Carfilzomib, Lenalidomide and Dexamethasone (Elo-KRd)

David M Foureau, Manisha Bhutani, Fei Guo, Kateryna Fesenkova, Shebli Atrash, Reed Friend, Barry Paul, Myra M Robinson, James T Symanowski, Lawrence J Druhan, Mauricio Pineda-Roman, Peter M. Voorhees, Saad Z. Usmani

Blood (2021) 138 (Supplement 1): 1585.

https://doi.org/10.1182/blood-2021-152505

Published: 2021

Journal Articles

Complex CSF3R Protein Isoform Interactions Dictate Cytokine Responsiveness

Sara L. Seegers, M.S., Amanda Lance, MS, Lawrence J Druhan, PhD, Belinda R Avalos, MD

Blood (2020) 136 (Supplement 1): 35.

https://doi.org/10.1182/blood-2020-143107

Published: 2020

Journal Articles

Alternative Splicing and Intronic Polyadenylation Post-Transcriptionally Regulate CSF3R Via a Cryptic Exon

Lawrence J Druhan, PhD, Amanda Lance, MS, Alicia Hamilton, Nury M Steuerwald, PhD, Elise Tjaden, Belinda R Avalos, MD

Blood (2019) 134 (Supplement_1): 2462.

https://doi.org/10.1182/blood-2019-129102

Published: 2019

Journal Articles

New Germline Syndrome Discovery: Heterozygous CSF3R Mutations May Predispose to Myeloid and Lymphoid Malignancies

Amy M Trottier, MDBSc,MSc, Ira L Kraft, MD, Lawrence J Druhan, PhD, Amanda Lance, MS, Belinda R Avalos, MD, Lucy A Godley, MD PhD

Blood (2019) 134 (Supplement_1): 2543.

https://doi.org/10.1182/blood-2019-129492

Published: 2019

Journal Articles

Mutations in SRSF2 Alter CSF3R Splicing in AML and Increase Expression of the V3 Variant Relative to V1

Lawrence J Druhan, PhD, Amanda Lance, MS, Carol G. Vestal, Andrea Price, Matthew Smith, Alicia Hamilton, Nury M Steuerwald, PhD, Belinda Rene Avalos, MD

Blood (2018) 132 (Supplement 1): 1106.

https://doi.org/10.1182/blood-2018-99-120000

Published: 2018

Journal Articles

Dual Inhibition of Aurora Kinase and BRD4 Leads to Improved Anti-Tumor Activity in Myc-Overexpressing Lymphoma Cells

Steven I Park, MD, Carolina Lin, Lawrence J Druhan, PhD, Michael B Foote, Trevor Parton, Natalie Ren, Steven P Angus, Aadra P Bhatt, Scott C Jaros, Nilanjan Ghosh, MD PhD, Ryan Jacobs, MD, Belinda Rene Avalos, MD, Dirk P Dittmer, PhD, Norman E. Sharpless, MD, Blossom A Damania

Blood (2017) 130 (Supplement 1): 4109.

https://doi.org/10.1182/blood.V130.Suppl_1.4109.4109

Published: 2017

Journal Articles

Correlation of Myeloid Derived Suppressor Cells and Response to Standard Chemoimmunotherapy in Diffuse Large B Cell Lymphoma

David M. Foureau, PhD, Qing Zhang, PhD, Lawrence J Druhan, PhD, Ryan Jacobs, MD, Fei Guo, PhD, Steven I Park, MD, Danyu Sun, MD PhD, Edward A Copelan, MD, Belinda Rene Avalos, MD, Nilanjan Ghosh, MD PhD

Blood (2017) 130 (Supplement 1): 4023.

https://doi.org/10.1182/blood.V130.Suppl_1.4023.4023

Published: 2017

NARROW

Myeloid Derived Suppressor Cell Kinetics in Peripheral Blood Correlate with Efficacy and Toxicity of CAR T Cell Therapy in Relapsed or Refractory B Cell Lymphoma

Socioeconomic Disadvantage Is Associated with Decreased Long-Term Survival in Adolescent and Young Adult Patients with Acute Lymphoblastic Leukemia

Enhanced Support Services Including Nurse Navigation Mitigate Socioeconomic Disparities in the Treatment of Patients with Acute Lymphoblastic Leukemia

MYC Pathway Upregulation Identified in Non-Responders to Hypomethylating Agents and Presents a Therapeutic Target in Acute Myeloid Leukemia

Factors Predicting Efficacy and Toxicity of Post Transplantation Cyclophosphamide for Graft Versus Host Disease Prevention in Hematopoietic Cell Transplantation Recipients: Interim Data of an Ongoing Study

Clonal Hematopoiesis Prevalence and Mutational Spectrum in Patients with Plasma Cell Disorders at the Time of Diagnosis and Its Impact on Clinical Features, Cardiovascular Complications, and Survival

Impact of Race, Ethnicity, and Social Determinants of Heath on Outcomes for Acute Myeloid Leukemia Patients in a System with Specialized Nurse Navigation

Heterodimerization of CSF3R Splice Variants and Mutants Alter Receptor Function

Impact of Polymorphisms in Pharmacokinetic Genes on Tyrosine Kinase Inhibitor (TKI) Tolerability in Patients with Chronic Myeloid Leukemia (CML) or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)

Aurora Kinase Inhibition Overcomes Primary Venetoclax Failure and Leads to Synthetic Lethality in BCL2-Positive Lymphomas Via Upregulation of P53/P21/BAX Axis

Phase II Trial of Elotuzumab in Combination with Carfilzomib, Lenalidomide and Dexamethasone for the Treatment of Relapsed/Refractory Multiple Myeloma (RRMM) after One Prior Line of Therapy

CSF3R Splicing Regulates Granulopoiesis Via Splice Variant Specific Responses to G-CSF

Hereditary Chronic Neutrophilic Leukemia in a Four Generation Family without Transformation to Acute Leukemia

Central Memory T-Cell Differentiation Correlates with Depth of Response in Relapsed/Refractory Multiple Myeloma Patients Receiving Elotuzumab in Combination with Carfilzomib, Lenalidomide and Dexamethasone (Elo-KRd)

Complex CSF3R Protein Isoform Interactions Dictate Cytokine Responsiveness

Alternative Splicing and Intronic Polyadenylation Post-Transcriptionally Regulate CSF3R Via a Cryptic Exon

New Germline Syndrome Discovery: Heterozygous CSF3R Mutations May Predispose to Myeloid and Lymphoid Malignancies

Mutations in SRSF2 Alter CSF3R Splicing in AML and Increase Expression of the V3 Variant Relative to V1

Dual Inhibition of Aurora Kinase and BRD4 Leads to Improved Anti-Tumor Activity in Myc-Overexpressing Lymphoma Cells

Correlation of Myeloid Derived Suppressor Cells and Response to Standard Chemoimmunotherapy in Diffuse Large B Cell Lymphoma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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