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Journal Articles

Individual Patient Dose-Escalated Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Vs.-Host Disease in Children and Adults: Safety, Efficacy and Immune Correlates

Blood (2017) 130 (Supplement 1): 3248.

https://doi.org/10.1182/blood.V130.Suppl_1.3248.3248

Published: 2017

Journal Articles

Initial Results of KD025-208: A Phase 2a Open Label Trial of KD025 for Steroid-Dependent Chronic Graft Versus Host Disease

Aleksandr Lazaryan, MD PhD MPH, Stephanie J Lee, MD MPH, Amandeep Salhotra, MD, Madan Jagasia, MD MBBS, MS, James Essell, MD, Alexandra Zanin-Zhorov, PhD, Beth Mac Gillivray, MSc, Olivier Schueller, PhD, David Eiznhamer, PhD, Bruce Blazar, MD, John L. Ryan, MD PhD

Blood (2017) 130 (Supplement 1): 3256.

https://doi.org/10.1182/blood.V130.Suppl_1.3256.3256

Published: 2017

Journal Articles

Cord Blood Regulatory T Cells for Prevention of Graft Versus Host Disease

Joshua Kellner, Stefan O. Ciurea, Amanda L. Olson, MD, Yago Nieto, MD PhD, Borje S Andersson, MDPhD, Joseph David Khoury, MD, Richard E. Champlin, MD, Stefan Nierkens, PhD, Jaap Jan Boelens, MD PhD, Bruce Blazar, MD, Simrit Parmar, MBBS

Blood (2017) 130 (Supplement 1): 3246.

https://doi.org/10.1182/blood.V130.Suppl_1.3246.3246

Published: 2017

Journal Articles

Neurological Consequences of Cytokine Release Syndrome Following Subcutaneous Recombinant IL-15 and Haploidentical Donor Natural Killer Cell Therapy for Advanced Acute Myeloid Leukemia

Sarah Cooley, MD, Fiona He, MD BS, BA, Veronika Bachanova, MD PhD, Greg M Vercellotti, MD FACP, Todd E. DeFor, MS, Julie Curtsinger, Paul Alexander Robertson, MD, Kevin C Conlon, MD, Thomas A Waldmann, MD, David H. McKenna, MD, Bruce Blazar, MD, Daniel J. Weisdorf, MD, Jeffrey S. Miller, MD

Blood (2017) 130 (Supplement 1): 2649.

https://doi.org/10.1182/blood.V130.Suppl_1.2649.2649

Published: 2017

Journal Articles

T Follicular Regulatory (TFR) Cell Deficiency during Chronic Graft-Versus-Host Disease Is Improved By Low-Dose IL-2 Therapy

Edouard Forcade, MD, Yusuke Kamihara, MD PhD, Haesook T Kim, PhD, Isabelle Douchet, John Koreth, MBBS, DPhil, Masahiro Hirakawa, MD PhD, Corey Cutler, MD MPH, FRCPC, Sarah Nikiforow, MD PhD, Vincent T Ho, MD, Philippe Armand, MD PhD, Edwin Alyea, III, MD, Patrick Blanco, MD PhD, Bruce Blazar, MD, Joseph H. Antin, MD, Robert J. Soiffer, MD, Jerome Ritz, MD

Blood (2017) 130 (Supplement 1): 4439.

https://doi.org/10.1182/blood.V130.Suppl_1.4439.4439

Published: 2017

Journal Articles

T Cell Costimulation Blockade with Abatacept Nearly Eliminates Early Severe Acute Graft Versus Host Disease after HLA-Mismatched (7/8 HLA Matched) Unrelated Donor Transplant, with a Favorable Impact on Disease-Free and Overall Survival

Blood (2017) 130 (Supplement 1): 212.

https://doi.org/10.1182/blood.V130.Suppl_1.212.212

Published: 2017

Journal Articles

Pre-Transplant Exhausted Marrow Infiltrating T Lymphocytes in MRD Negative Patients with Acute Leukemia Predict Early Relapse Following Allogeneic Hematopoietic Stem Cell Transplantation

Robin Williams, MDMS, Sarah Cooley, MD, Peter M. Gordon, MDPhD, Veronika Bachanova, MD PhD, Daniel J. Weisdorf, MD, Bruce Blazar, MD, John E. Wagner, MD, Jeffrey S. Miller, MD, Michael R Verneris, MD

Blood (2017) 130 (Supplement 1): 1997.

https://doi.org/10.1182/blood.V130.Suppl_1.1997.1997

Published: 2017

Journal Articles

Id3 Is Essential for Mediating Ezh2-Regulated Persistence of Alloreactive T Cells in Gvhd Target Tissues in Mice

Shan He, PhD, Yuanyuan Tian, Yongnian Liu, Ying Wang, Bruce Blazar, MD, Ximi K Wang, Ran Reshef, MD, Yi Zhang, MD

Blood (2017) 130 (Supplement 1): 210.

https://doi.org/10.1182/blood.V130.Suppl_1.210.210

Published: 2017

Journal Articles

Amphiregulin Improves Stratification of the Refined Minnesota Acute Graft-Versus-Host Disease Risk Score: Results from BMT CTN 0302/0802

Blood (2017) 130 (Supplement 1): 72.

https://doi.org/10.1182/blood.V130.Suppl_1.72.72

Published: 2017

Journal Articles

A Critical Role for Donor-Derived IL-22 in Cutaneous Chronic Gvhd

Blood (2017) 130 (Supplement 1): 69.

https://doi.org/10.1182/blood.V130.Suppl_1.69.69

Published: 2017

Journal Articles

Clinical Translation of Pluripotent Cell-Derived Off-the-Shelf Natural Killer Cell Cancer Immunotherapy

Blood (2017) 130 (Supplement 1): 656.

https://doi.org/10.1182/blood.V130.Suppl_1.656.656

Published: 2017

Journal Articles

Low-Dose Interleukin-2 Therapy Activates Circulating T Follicular Regulatory Cells and Suppresses Circulating T Follicular Helper Cells in Patients with Chronic Gvhd

Yusuke Kamihara, MD PhD, Edouard Forcade, MD, John Koreth, MBBS, DPhil, Hongye Liu, PhD, Tomohiro Kubo, MD PhD, Jennifer Whangbo, MD PhD, Masahiro Hirakawa, MD PhD, Sarah Nikiforow, MD PhD, Vincent T Ho, MD, Philippe Armand, MD PhD, Corey S. Cutler, MD MPH, Edwin Alyea, III, MD, Bruce Blazar, MD, Joseph H. Antin, MD, Robert J. Soiffer, MD, Jerome Ritz, MD

Blood (2017) 130 (Supplement 1): 74.

https://doi.org/10.1182/blood.V130.Suppl_1.74.74

Published: 2017

Journal Articles

Pediatric Acute GVHD Grade, Risk Prediction and Response to Upfront Steroids in 370 Children Treated at the University of Minnesota

Margaret L. MacMillan, MD, Shernan G. Holtan, MD, Armin Rashidi, MD PhD, Todd E. DeFor, MS, Bruce Blazar, MD, Daniel J. Weisdorf, MD

Blood (2017) 130 (Supplement 1): 4486.

https://doi.org/10.1182/blood.V130.Suppl_1.4486.4486

Published: 2017

Journal Articles

First-in-Human Clinical Trial of the IL-15 Super-Agonist Complex ALT-803 for Patients Relapsed after Allogeneic Hematopoietic Cell Transplantation

Rizwan Romee, MD, Sarah Cooley, MD, Melissa Berrien-Elliott, PhD, Peter Westervelt, MDPhD, Michael R Verneris, MD, John E. Wagner, MD, Daniel J. Weisdorf, MD, Bruce Blazar, MD, John F DiPersio, MD PhD, Amanda F. Cashen, MD, Emily K Jeng, Amy Rock, Hing C Wong, PhD, Todd A. Fehniger, MDPhD, Jeffrey S. Miller, MD

Blood (2017) 130 (Supplement 1): 274.

https://doi.org/10.1182/blood.V130.Suppl_1.274.274

Published: 2017

Journal Articles

Extra-Corporeal Photopheresis Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Vs.-Host Disease: Efficacy, Safety and Immune Correlates

John Koreth, MBBS, DPhil, Haesook T Kim, PhD, Roger Belizaire, MD PhD, Samuel J Poryanda, BSc, Carol Reynolds, PhD, Jennifer Whangbo, MD PhD, Sarah Nikiforow, Edwin Alyea, III, MD, Philippe Armand, MD PhD, Corey Cutler, MD MPH, FRCPC, Vincent T Ho, MD, Bruce Blazar, MD, Joseph H. Antin, MD, Jerome Ritz, MD, Robert J. Soiffer, MD

Blood (2017) 130 (Supplement 1): 515.

https://doi.org/10.1182/blood.V130.Suppl_1.515.515

Published: 2017

Journal Articles

Phase I Trial of Regulatory T-Cell Donor Lymphocyte Infusion Plus Daily Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Versus-Host Disease

Blood (2017) 130 (Supplement 1): 511.

https://doi.org/10.1182/blood.V130.Suppl_1.511.511

Published: 2017

Journal Articles

A Novel Process for the Expansion of Functional Human ILC2 Cells for GCHD Prevention

Yan Xing, MDPhD, Heather Stefanski, MD PhD, Danny W. Bruce, PhD, Keli Lee Hippen, PhD, James M. Coghill, Jr., MD, Karen McKinnon, PhD, Shannon Reisdorf, BS, Bruce Blazar, MD, Jonathan S Serody, MD

Blood (2017) 130 (Supplement 1): 4432.

https://doi.org/10.1182/blood.V130.Suppl_1.4432.4432

Published: 2017

Journal Articles

Transplanted Donor APC Co-Stimulatory Molecule Expression Is Required To Elicit Host T Cell Resistance in MHC-Matched Allogeneic BMT Recipients Following Reduced Intensity Conditioning.

Monica Jones, Bruce Blazar, MD, Zachary Zimmerman, PhD, Robert B. Levy, PhD

Blood (2006) 108 (11): 620.

https://doi.org/10.1182/blood.V108.11.620.620

Published: 2006

Journal Articles

Immunotherapy of EBV Post Solid Organ Transplantation Lymphoproliferative Disease with Genetically Engineered Haploidentical T Cells.

Paul J. Orchard, MD, Jakub Tolar, MD, PhD, Lisa Basso, Claudio Brunstein, MD, PhD, Marcie Tomblyn, MD, Scott Baker, MD, Bruce Blazar, MD, John Wagner, MD, Jeffrey S. Miller, MD

Blood (2005) 106 (11): 5541.

https://doi.org/10.1182/blood.V106.11.5541.5541

Published: 2005

Journal Articles

Visualizing Allogeneic Bone Marrow (BM) Graft Rejection.

Patricia Taylor, DVM, Angela Panoskaltsis-Mortari, PhD, Randolph Noelle, PhD, Alexander Rudensky, PhD, Jonathan Serody, MD, PhD, Bruce Blazar, MD

Blood (2004) 104 (11): 43.

https://doi.org/10.1182/blood.V104.11.43.43

Published: 2004

NARROW

Individual Patient Dose-Escalated Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Vs.-Host Disease in Children and Adults: Safety, Efficacy and Immune Correlates

Initial Results of KD025-208: A Phase 2a Open Label Trial of KD025 for Steroid-Dependent Chronic Graft Versus Host Disease

Cord Blood Regulatory T Cells for Prevention of Graft Versus Host Disease

Neurological Consequences of Cytokine Release Syndrome Following Subcutaneous Recombinant IL-15 and Haploidentical Donor Natural Killer Cell Therapy for Advanced Acute Myeloid Leukemia

T Follicular Regulatory (TFR) Cell Deficiency during Chronic Graft-Versus-Host Disease Is Improved By Low-Dose IL-2 Therapy

T Cell Costimulation Blockade with Abatacept Nearly Eliminates Early Severe Acute Graft Versus Host Disease after HLA-Mismatched (7/8 HLA Matched) Unrelated Donor Transplant, with a Favorable Impact on Disease-Free and Overall Survival

Pre-Transplant Exhausted Marrow Infiltrating T Lymphocytes in MRD Negative Patients with Acute Leukemia Predict Early Relapse Following Allogeneic Hematopoietic Stem Cell Transplantation

Id3 Is Essential for Mediating Ezh2-Regulated Persistence of Alloreactive T Cells in Gvhd Target Tissues in Mice

Amphiregulin Improves Stratification of the Refined Minnesota Acute Graft-Versus-Host Disease Risk Score: Results from BMT CTN 0302/0802

A Critical Role for Donor-Derived IL-22 in Cutaneous Chronic Gvhd

Clinical Translation of Pluripotent Cell-Derived Off-the-Shelf Natural Killer Cell Cancer Immunotherapy

Low-Dose Interleukin-2 Therapy Activates Circulating T Follicular Regulatory Cells and Suppresses Circulating T Follicular Helper Cells in Patients with Chronic Gvhd

Pediatric Acute GVHD Grade, Risk Prediction and Response to Upfront Steroids in 370 Children Treated at the University of Minnesota

First-in-Human Clinical Trial of the IL-15 Super-Agonist Complex ALT-803 for Patients Relapsed after Allogeneic Hematopoietic Cell Transplantation

Extra-Corporeal Photopheresis Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Vs.-Host Disease: Efficacy, Safety and Immune Correlates

Phase I Trial of Regulatory T-Cell Donor Lymphocyte Infusion Plus Daily Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-Versus-Host Disease

A Novel Process for the Expansion of Functional Human ILC2 Cells for GCHD Prevention

Transplanted Donor APC Co-Stimulatory Molecule Expression Is Required To Elicit Host T Cell Resistance in MHC-Matched Allogeneic BMT Recipients Following Reduced Intensity Conditioning.

Immunotherapy of EBV Post Solid Organ Transplantation Lymphoproliferative Disease with Genetically Engineered Haploidentical T Cells.

Visualizing Allogeneic Bone Marrow (BM) Graft Rejection.

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American Society of Hematology

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American Society of Hematology

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