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Journal Articles

The Transcription Factor PU.1 Controls Alternative Splicing of Cflip By Binding to SRSF2/10 Splice Factors in AML Therapy Responses

Nicolas Niklaus, Magali Humbert, Bruce E. Torbett, Mario P. Tschan

Blood (2022) 140 (Supplement 1): 8742–8743.

https://doi.org/10.1182/blood-2022-157921

Published: 2022

Journal Articles

Non-Glycolytic Role of the Myeloid Hexokinase 3 (HK3) in Therapy Responses of Myeloid Malignancies

Kristina Seiler, Mario P. Tschan, Carmen Kalbermatter, Tanja Muralt, Tata Nageswara Rao, Bruce E. Torbett

Blood (2022) 140 (Supplement 1): 5883.

https://doi.org/10.1182/blood-2022-157499

Published: 2022

Journal Articles

Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes

Blood (2019) 134 (16): 1298–1311.

https://doi.org/10.1182/blood.2019000040

Published: 2019

Includes: Supplemental data

Journal Articles

A Novel PU.1 - Caspase 8/cFLIP Axis in Neutrophil and Macrophage Differentiation of AML Cells

Magali Humbert, PhD, Mario P. Tschan, PhD, Aladin Haimovici, Bruce E. Torbett, PhD, Nicolas Niklaus, MSc, BSc

Blood (2018) 132 (Supplement 1): 1347.

https://doi.org/10.1182/blood-2018-99-112797

Published: 2018

Journal Articles

Hexokinase Proteins Impart Distinct Functions in Myeloid Development and Cell Death

Kristina Seiler, MD, Petra Minder, PhD, Iris Mashimo, Magali Humbert, PhD, Elizabeth Simpson, Mario P. Tschan, PhD, Bruce E. Torbett, PhD

Blood (2018) 132 (Supplement 1): 5088.

https://doi.org/10.1182/blood-2018-99-112145

Published: 2018

Journal Articles

Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells

Cathy X. Wang, Blythe D. Sather, Xuefeng Wang, Jennifer Adair, Iram Khan, Swati Singh, Shanshan Lang, Amie Adams, Gabrielle Curinga, Hans-Peter Kiem, Carol H. Miao, David J. Rawlings, Bruce E. Torbett

Blood (2014) 124 (6): 913–923.

https://doi.org/10.1182/blood-2013-12-546218

Published: 2014

Includes: Supplemental data

Journal Articles

Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor

Fouzia Amirache, Camille Lévy, Caroline Costa, Philippe-Emmanuel Mangeot, Bruce E. Torbett, Cathy X. Wang, Didier Nègre, François-Loïc Cosset, Els Verhoeyen

Blood (2014) 123 (9): 1422–1424.

https://doi.org/10.1182/blood-2013-11-540641

Published: 2014

Includes: Supplemental data

Journal Articles

PU.1 is linking the glycolytic enzyme HK3 in neutrophil differentiation and survival of APL cells

Elena A. Federzoni, Peter J. M. Valk, Bruce E. Torbett, Torsten Haferlach, Bob Löwenberg, Martin F. Fey, Mario P. Tschan

Blood (2012) 119 (21): 4963–4970.

https://doi.org/10.1182/blood-2011-09-378117

Published: 2012

Includes: Supplemental data

Journal Articles

The Anti-Apoptotic Gene BCL2A1 Is Transcriptionally Regulated by PU.1

Mathias Jenal, MSc, Venkateshwar A. Reddy, PhD, Judith Laedrach, Deborah Shan, Andreas Tobler, MD, Bruce E. Torbett, PhD, Martin F. Fey, MD, Mario P. Tschan, PhD

Blood (2008) 112 (11): 3579.

https://doi.org/10.1182/blood.V112.11.3579.3579

Published: 2008

Journal Articles

C/EBPα binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment

Christine Yeamans, Dehua Wang, Ido Paz-Priel, Bruce E. Torbett, Daniel G. Tenen, Alan D. Friedman

Blood (2007) 110 (9): 3136–3142.

https://doi.org/10.1182/blood-2007-03-080291

Published: 2007

Journal Articles

Identification of PU.1 Target Genes That Are Dependent on Specific Functional Domains of the Transcription Factor PU.1.

Gabriele E. Foos, Kimberlee M. Fischer, Jeremiah Savage, Venkat Reddy, Bruce E. Torbett

Blood (2006) 108 (11): 1174.

https://doi.org/10.1182/blood.V108.11.1174.1174

Published: 2006

Journal Articles

A Cyclophilin A-Independent Capsid Motif Renders HIV-1 Derived Vectors More Efficient at Transducing Human Cells.

Christina H. Swan, BS, Udayan Chatterji, PhD, Philippe Gallay, PhD, Bruce E. Torbett, PhD, MSP.H.

Blood (2005) 106 (11): 5531.

https://doi.org/10.1182/blood.V106.11.5531.5531

Published: 2005

Journal Articles

Enhancing Neutrophil Differentiation - A Novel Role for the Death-Associated Protein Kinase 2 (DAPK2).

Mattia Rizzi, MD, Christian Britschgi, MD, Mario P. Tschan, PhD, Tobias J. Grob, MD, PhD, Barbara Huegli, Nicolas Leupin, MD, Beatrice U. Mueller, MD, Andrew Ziemiecki, PhD, Bruce E. Torbett, PhD, Martin F. Fey, MD, Andreas Tobler, MD

Blood (2005) 106 (11): 1348.

https://doi.org/10.1182/blood.V106.11.1348.1348

Published: 2005

Journal Articles

Lentiviral CCR5 Intrabody Gene Delivery Provides Protection and Enrichment during CCR5-Tropic Infection.

Christina H. Swan, Bernd Buhler, Ph.D., Mario P. Tschan, Ph.D., Carlos F. Barbas, III, Ph.D., Bruce E. Torbett, Ph.D.

Blood (2004) 104 (11): 1755.

https://doi.org/10.1182/blood.V104.11.1755.1755

Published: 2004

Journal Articles

CD34+ Cell Derived Macrophages Are Protected from HIV-1 Challenge by Intrabody-Mediated Reduction of CCR5.

Kimberlee M. Fischer, BS, Margaret L. Just, PhD, Carlos F. Barbas, PhD, Bruce E. Torbett, PhD

Blood (2004) 104 (11): 1756.

https://doi.org/10.1182/blood.V104.11.1756.1756

Published: 2004

Journal Articles

Development of a Unique siRNA and Intrabody Combinatorial HIV-1 Vector to Knockdown CXCR4 and Protect Cells from HIV-1 Challenge.

Christina H. Swan, Mario P. Tschan, Ph.D., Carlos F. Barbas, III, Ph.D., Bruce E. Torbett, Ph.D.

Blood (2004) 104 (11): 1757.

https://doi.org/10.1182/blood.V104.11.1757.1757

Published: 2004

Journal Articles

Understanding Hematogenous Breast Cancer Metastasis: Tumor Cell Integrin Activation Matters.

Martin R. Weber, M.D., Deidre O’Sullivan, Ph.D, Mario P. Tschan, Ph.D, Bruce E. Torbett, Ph.D, Andries Zijlstra, Ph.D, James P. Quigley, Ph.D, Brunhilde Felding-Habermann, Ph.D

Blood (2004) 104 (11): 2613.

https://doi.org/10.1182/blood.V104.11.2613.2613

Published: 2004

Journal Articles

The role of angiopoietins in the development of endothelial cells from cord blood CD34 + progenitors

Patrick Hildbrand, Vincenzo Cirulli, Robyn C. Prinsen, Kent A. Smith, Bruce E. Torbett, Daniel R. Salomon, Laura Crisa

Blood (2004) 104 (7): 2010–2019.

https://doi.org/10.1182/blood-2003-12-4219

Published: 2004

Includes: Supplemental data

Journal Articles

Regulation of neutrophil and eosinophil secondary granule gene expression by transcription factors C/EBPε and PU.1

Adrian F. Gombart, Scott H. Kwok, Karen L. Anderson, Yuji Yamaguchi, Bruce E. Torbett, H. Phillip Koeffler

Blood (2003) 101 (8): 3265–3273.

https://doi.org/10.1182/blood-2002-04-1039

Published: 2003

Journal Articles

PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding

Pu Zhang, Xiaobo Zhang, Atsushi Iwama, Channing Yu, Kent A. Smith, Beatrice U. Mueller, Salaija Narravula, Bruce E. Torbett, Stuart H. Orkin, Daniel G. Tenen

Blood (2000) 96 (8): 2641–2648.

https://doi.org/10.1182/blood.V96.8.2641

Published: 2000

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The Transcription Factor PU.1 Controls Alternative Splicing of Cflip By Binding to SRSF2/10 Splice Factors in AML Therapy Responses

Non-Glycolytic Role of the Myeloid Hexokinase 3 (HK3) in Therapy Responses of Myeloid Malignancies

Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes

A Novel PU.1 - Caspase 8/cFLIP Axis in Neutrophil and Macrophage Differentiation of AML Cells

Hexokinase Proteins Impart Distinct Functions in Myeloid Development and Cell Death

Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells

Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor

PU.1 is linking the glycolytic enzyme HK3 in neutrophil differentiation and survival of APL cells

The Anti-Apoptotic Gene BCL2A1 Is Transcriptionally Regulated by PU.1

C/EBPα binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment

Identification of PU.1 Target Genes That Are Dependent on Specific Functional Domains of the Transcription Factor PU.1.

A Cyclophilin A-Independent Capsid Motif Renders HIV-1 Derived Vectors More Efficient at Transducing Human Cells.

Enhancing Neutrophil Differentiation - A Novel Role for the Death-Associated Protein Kinase 2 (DAPK2).

Lentiviral CCR5 Intrabody Gene Delivery Provides Protection and Enrichment during CCR5-Tropic Infection.

CD34+ Cell Derived Macrophages Are Protected from HIV-1 Challenge by Intrabody-Mediated Reduction of CCR5.

Development of a Unique siRNA and Intrabody Combinatorial HIV-1 Vector to Knockdown CXCR4 and Protect Cells from HIV-1 Challenge.

Understanding Hematogenous Breast Cancer Metastasis: Tumor Cell Integrin Activation Matters.

The role of angiopoietins in the development of endothelial cells from cord blood CD34 + progenitors

Regulation of neutrophil and eosinophil secondary granule gene expression by transcription factors C/EBPε and PU.1

PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding

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