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Charles Sawyers
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Journal Articles

Clonal Hematopoiesis in Philadelphia Chromosome-Negative Bone Marrow Cells of Chronic Myeloid Leukemia Patients Receiving Tyrosine Kinase Inhibitors

Ron Paquette, MD, John Nicoll, Meenal Chalukya, Lukasz P Gondek, MD, PhD, Monika Jasek, Charles Sawyers, MD, Neil Shah, MD, PhD, Jaroslaw Maciejewski
Journal: Blood
Blood (2008) 112 (11): 575.
https://doi.org/10.1182/blood.V112.11.575.575
Published: 2008
Journal Articles

Favorable long-term follow-up results over 6 years for response, survival, and safety with imatinib mesylate therapy in chronic-phase chronic myeloid leukemia after failure of interferon-α treatment

Clinical Trials & Observations
Andreas Hochhaus, Brian Druker, Charles Sawyers, Francois Guilhot, Charles A. Schiffer, Jorge Cortes, Dietger W. Niederwieser, Carlo Gambacorti-Passerini, Richard M. Stone, John Goldman, Thomas Fischer, Stephen G. O'Brien, Jose J. Reiffers, Manisha Mone, Tillmann Krahnke, Moshe Talpaz, Hagop M. Kantarjian
Journal: Blood
Blood (2008) 111 (3): 1039–1043.
https://doi.org/10.1182/blood-2007-07-103523
Published: 2008
Journal Articles

Six Year Follow-Up Results of a Phase II Study of Imatinib in Late Chronic Phase (L-CP) Chronic Myeloid Leukemia (CML) Post Interferon-A (IFN) Refractoriness/Intolerance.

Hagop M. Kantarjian, Charles Sawyers, Andreas Hochhaus, Charles A. Schiffer, Francois Guilhot, Dietger W. Niederwieser, Carlo Gambacorti, Richard M. Stone, Thomas Fischer, John Goldman, T. Krahnke, M. Mone, Moshe Talpaz, Brian J. Druker
Journal: Blood
Blood (2006) 108 (11): 428.
https://doi.org/10.1182/blood.V108.11.428.428
Published: 2006
Journal Articles

Adaphostin-induced oxidative stress overcomes BCR/ABL mutation-dependent and -independent imatinib resistance

Joya Chandra, Jeannette Tracy, David Loegering, Karen Flatten, Srdan Verstovsek, Miloslav Beran, Mercedes Gorre, Zeev Estrov, Nicholas Donato, Moshe Talpaz, Charles Sawyers, Kapil Bhalla, Judith Karp, Edward Sausville, Scott H. Kaufmann
Journal: Blood
Blood (2006) 107 (6): 2501–2506.
https://doi.org/10.1182/blood-2005-07-2966
Published: 2006
Journal Articles

Major Molecular Responses to Dasatinib (BMS-354825) Are Observed in Imatinib-Resistant Late Stage Chronic and Advanced CML Patients: Impact and Fate of Imatinib-Resistant Clones in Dasatinib-Treated Patients.

Susan Branford, Timothy Hughes, John Nicoll, Ron Paquette, Eric Bleickardt, Charles Sawyers, Neil Shah
Journal: Blood
Blood (2005) 106 (11): 437.
https://doi.org/10.1182/blood.V106.11.437.437
Published: 2005
Journal Articles

Hematologic and Cytogenetic Responses in Imatinib-Resistant Accelerated and Blast Phase Chronic Myeloid Leukemia (CML) Patients Treated with the Dual SRC/ABL Kinase Inhibitor BMS-354825: Results from a Phase I Dose Escalation Study.

Moshe Talpaz, Hagop Kantarjian, Neil P. Shah, Nicholas Donato, John Nicoll, Stephen A. Bai, Fei Huang, Edwin Clark, Arthur P. DeCillis, Charles Sawyers
Journal: Blood
Blood (2004) 104 (11): 20.
https://doi.org/10.1182/blood.V104.11.20.20
Published: 2004
Journal Articles

Effects of Adaphostin, a Novel Tyrphostin Inhibitor, in Diverse Models of Imatinib Mesylate Resistance.

Joya Chandra, Ph.D., Jeannette Tracy, Mercedes Gorre, Ph.D., Moshe Talpaz, M.D., James Griffin, M.D., Srdan Verstovsek, M.D., Ph.D., Miloslav Beran, M.D., Charles Sawyers, M.D., Edward Sausville, M.D., Scott Kaufmann, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 2097.
https://doi.org/10.1182/blood.V104.11.2097.2097
Published: 2004
Journal Articles

Interleukin-6–Induced Inhibition of Multiple Myeloma Cell Apoptosis: Support for the Hypothesis That Protection Is Mediated Via Inhibition of the JNK/SAPK Pathway

Feng-hao Xu, Sanjesh Sharma, Agnes Gardner, Yiping Tu, Arthur Raitano, Charles Sawyers, Alan Lichtenstein
Journal: Blood
Blood (1998) 92 (1): 241–251.
https://doi.org/10.1182/blood.V92.1.241.413k28_241_251
Published: 1998