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Costas M. Pitsillides
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Journal Articles

Primary Waldesntrom Macroglobulinemia Cells Harbor Constitutive Activation of Akt, mTOR, Rictor and Raptor: Rational for Testing a Dual Inhibitor of the PI3K/Akt and mTOR Pathways in This Disease.

Aldo M. Roccaro, MD, PhD, Antonio Sacco, Emanuel N. Husu, Costas M Pitsillides, PhD, Steven Vesole, Abdel Kareem Azab, BPharm, PhD, Feda Azab, BPharm, Molly Melhem, Hai Ngo, Phong Quang, Patricia Maiso, PhD, Judith M. Runnels, PhD, Charles P. Lin, PhD, Kenneth C. Anderson, MD, Irene Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 3843.
https://doi.org/10.1182/blood.V114.22.3843.3843
Published: 2009
Journal Articles

Role of Selectins in the Pathogenesis of Multiple Myeloma.

Abdel Kareem Azab, Bpharm, PhD, Phong Quang, Feda Azab, BPharm, Costas M Pitsillides, John T Patton, Theodore Smith, Arun Sarkar, Judith M. Runnels, PhD, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Hai T. Ngo, Molly R Melhem, Patricia Maiso, PhD, Kenneth C. Anderson, MD, Charles P. Lin, PhD, John L. Magnani, Irene M. Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 951.
https://doi.org/10.1182/blood.V114.22.951.951
Published: 2009
Journal Articles

RhoA and Rac1 GTPases play major and differential roles in stromal cell–derived factor-1–induced cell adhesion and chemotaxis in multiple myeloma

Abdel Kareem Azab, Feda Azab, Simona Blotta, Costas M. Pitsillides, Brian Thompson, Judith M. Runnels, Aldo M. Roccaro, Hai T. Ngo, Molly R. Melhem, Antonio Sacco, Xiaoying Jia, Kenneth C. Anderson, Charles P. Lin, Barrett J. Rollins, Irene M. Ghobrial
Journal: Blood
Blood (2009) 114 (3): 619–629.
https://doi.org/10.1182/blood-2009-01-199281
Published: 2009
Includes: Multimedia, Supplemental data
Journal Articles

Rho-a and Rac-1 GTPases Play Major and Differential Roles in SDF1α- Induced Cell Adhesion and Chemotaxis in Multiple Myeloma.

Abdel kareem Azab, Feda Azab, Costas M Pitsillides, Hai T. Ngo, Xiaoying Jia, Molly R. Melhem, Judith Runnels, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Nicholas Burwick, Charles P Lin, Kenneth C Anderson, MD, Irene M. Ghobrial
Journal: Blood
Blood (2008) 112 (11): 1666.
https://doi.org/10.1182/blood.V112.11.1666.1666
Published: 2008
Journal Articles

The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia

Xavier Leleu, Xiaoying Jia, Judith Runnels, Hai T. Ngo, Anne-Sophie Moreau, Mena Farag, Joel A. Spencer, Costas M. Pitsillides, Evdoxia Hatjiharissi, Aldo Roccaro, Garrett O'Sullivan, Douglas W. McMillin, Daisy Moreno, Tanyel Kiziltepe, Ruben Carrasco, Steven P. Treon, Teru Hideshima, Kenneth C. Anderson, Charles P. Lin, Irene M. Ghobrial
Journal: Blood
Blood (2007) 110 (13): 4417–4426.
https://doi.org/10.1182/blood-2007-05-092098
Published: 2007
Journal Articles

Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)–dependent migration and homing in multiple myeloma

Yazan Alsayed, Hai Ngo, Judith Runnels, Xavier Leleu, Ujjal K. Singha, Costas M. Pitsillides, Joel A. Spencer, Teresa Kimlinger, Joanna M. Ghobrial, Xiaoying Jia, Ganwei Lu, Michael Timm, Ashok Kumar, Daniel Côté, Israel Veilleux, Karen E. Hedin, G. David Roodman, Thomas E. Witzig, Andrew L. Kung, Teru Hideshima, Kenneth C. Anderson, Charles P. Lin, Irene M. Ghobrial
Journal: Blood
Blood (2006) 109 (7): 2708–2717.
https://doi.org/10.1182/blood-2006-07-035857
Published: 2006