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Journal Articles

CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy

Abdel Kareem Azab, Judith M. Runnels, Costas Pitsillides, Anne-Sophie Moreau, Feda Azab, Xavier Leleu, Xiaoying Jia, Renee Wright, Beatriz Ospina, Alicia L. Carlson, Clemens Alt, Nicholas Burwick, Aldo M. Roccaro, Hai T. Ngo, Mena Farag, Molly R. Melhem, Antonio Sacco, Nikhil C. Munshi, Teru Hideshima, Barrett J. Rollins, Kenneth C. Anderson, Andrew L. Kung, Charles P. Lin, Irene M. Ghobrial
Journal: Blood
Blood (2009) 113 (18): 4341–4351.
https://doi.org/10.1182/blood-2008-10-186668
Published: 2009
Includes: Supplemental data
Journal Articles

Endoplasmic reticulum stress is a target for therapy in Waldenstrom macroglobulinemia

Xavier Leleu, Lian Xu, Xiaoying Jia, Antonio Sacco, Mena Farag, Zachary R. Hunter, Anne-Sophie Moreau, Hai T. Ngo, Evdoxia Hatjiharissi, Allen W. Ho, Daniel D. Santos, Sofia Adamia, Kelly O'Connor, Bryan Ciccarelli, Jacob Soumerai, Robert J. Manning, Christopher J. Patterson, Aldo M. Roccaro, Irene M. Ghobrial, Steven P. Treon
Journal: Blood
Blood (2009) 113 (3): 626–634.
https://doi.org/10.1182/blood-2007-10-116848
Published: 2009
Journal Articles

The Tyrosine Kinase Src Regulates Adhesion and Survival in Waldenström Macroglobulinemia

Hai T. Ngo, Mena Farag, Xiaoying Jia, Nicolas Burwick, MD, Molly R. Melhem, Xavier Leleu, MD, PhD, Judith Runnels, PhD, Abdel Kareem Azab, PhD, Aldo M. Roccaro, MD, PhD, Feda Azab, Antonio Sacco, Phong Quang, Yu-Tzu Tai, PhD, Kenneth C. Anderson, MD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2008) 112 (11): 2615.
https://doi.org/10.1182/blood.V112.11.2615.2615
Published: 2008
Journal Articles

The Effect of Insulin-Like Growth Factor 1 on Waldenstrom Macroglobulinemia

Molly R. Melhem, Aldo M. Roccaro, MD, PhD, Mena Farag, Abdel kareem Azab, PhD, Hai T. Ngo, Antonio Sacco, Xiaoying Jia, Feda Azab, Judith Runnels, PhD, Nicolas Burwick, MD, Phong Quang, Emanuel N. Husu, Hideshima Teru, MD, PhD, Kenneth C. Anderson, MD, Xavier Leleu, MD, PhD, Irene M. Ghobrial, M.D.
Journal: Blood
Blood (2008) 112 (11): 4994.
https://doi.org/10.1182/blood.V112.11.4994.4994
Published: 2008
Journal Articles

Proteomic Analysis of Multiple Myeloma Identifies Upregulation of CRIK Protein, a Novel Protein Regulating Migration and Adhesion

Hai T. Ngo, Evdoxia Hatjiharissi, MD, Alexey A. Leontovich, PhD, Wee Chng, PhD, Mena Farag, Xavier Leleu, MD, PhD, Xiaoying Jia, Judith Runnels, PhD, Aldo Roccaro, MD, PhD, Abdel Kareem Azab, PhD, Feda Azab, Antonio Sacco, Nicholas Burwick, MD, Molly R. Melhem, Kenneth C. Anderson, MD, Rafael Fonseca, MD, Thomas E. Witzig, MD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2008) 112 (11): 643.
https://doi.org/10.1182/blood.V112.11.643.643
Published: 2008
Journal Articles

SDF-1/CXCR4 and VLA-4 interaction regulates homing in Waldenstrom macroglobulinemia

Hai T. Ngo, Xavier Leleu, Jack Lee, Xiaoying Jia, Molly Melhem, Judith Runnels, Anne-Sophie Moreau, Nicholas Burwick, Abdel Kareem Azab, Aldo Roccaro, Feda Azab, Antonio Sacco, Mena Farag, Robert Sackstein, Irene M. Ghobrial
Journal: Blood
Blood (2008) 112 (1): 150–158.
https://doi.org/10.1182/blood-2007-12-129395
Published: 2008
Journal Articles

Targeting NF-κB in Waldenstrom macroglobulinemia

Xavier Leleu, Jérôme Eeckhoute, Xiaoying Jia, Aldo M. Roccaro, Anne-Sophie Moreau, Mena Farag, Antonio Sacco, Hai T. Ngo, Judith Runnels, Molly R. Melhem, Nicolas Burwick, Abdelkareem Azab, Feda Azab, Zachary Hunter, Evdoxia Hatjiharissi, Daniel R. Carrasco, Steven P. Treon, Thomas E. Witzig, Teru Hideshima, Myles Brown, Kenneth C. Anderson, Irene M. Ghobrial
Journal: Blood
Blood (2008) 111 (10): 5068–5077.
https://doi.org/10.1182/blood-2007-09-115170
Published: 2008
Journal Articles

Dual targeting of the proteasome regulates survival and homing in Waldenström macroglobulinemia

Aldo M. Roccaro, Xavier Leleu, Antonio Sacco, Xiaoying Jia, Molly Melhem, Anne-Sophie Moreau, Hai T. Ngo, Judith Runnels, Abdelkareem Azab, Feda Azab, Nicholas Burwick, Mena Farag, Steven P. Treon, Michael A. Palladino, Teru Hideshima, Dharminder Chauhan, Kenneth C. Anderson, Irene M. Ghobrial
Journal: Blood
Blood (2008) 111 (9): 4752–4763.
https://doi.org/10.1182/blood-2007-11-120972
Published: 2008
Includes: Supplemental data
Journal Articles

The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia

Xavier Leleu, Xiaoying Jia, Judith Runnels, Hai T. Ngo, Anne-Sophie Moreau, Mena Farag, Joel A. Spencer, Costas M. Pitsillides, Evdoxia Hatjiharissi, Aldo Roccaro, Garrett O'Sullivan, Douglas W. McMillin, Daisy Moreno, Tanyel Kiziltepe, Ruben Carrasco, Steven P. Treon, Teru Hideshima, Kenneth C. Anderson, Charles P. Lin, Irene M. Ghobrial
Journal: Blood
Blood (2007) 110 (13): 4417–4426.
https://doi.org/10.1182/blood-2007-05-092098
Published: 2007
Journal Articles

The Interaction of CXCR4/SDF-1 and VLA-4 Regulates Adhesion and Transendothelial Migration in Waldenstrom Macroglobulinemia.

Hai T. Ngo, Mena Farag, Xavier Leleu, Xiaoying Jia, Judith Runnels, Anne-Sophie Moreau, Abdelkareem Azab, Feda Azab, Evdoxia Hatjiharissi, Aldo Roccaro, Antonio Sacco, Irene M. Ghobrial
Journal: Blood
Blood (2007) 110 (11): 2617.
https://doi.org/10.1182/blood.V110.11.2617.2617
Published: 2007
Journal Articles

Targeting NF-kB by Perifosine, Bortezomib and Rituximab in Waldenstrom Macroglobulinemia (WM).

Xavier Leleu, MD, Eeckhoute Jerome, PhD, Xiaoying Jia, Anne-Sophie Moreau, MD, Aldo M. Roccaro, MD, Mena Farag, Antonio Sacco, Evdoxia Hatjiharissi, MD, Hai T. Ngo, Judith Runnels, PhD, Abdelkareem Azab, PhD, Feda Azab, Zachary Hunter, Peter Sportelli, Steven P. Treon, MD, Teru Hideshima, MD, Kenneth C. Anderson, MD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2007) 110 (11): 2512.
https://doi.org/10.1182/blood.V110.11.2512.2512
Published: 2007
Journal Articles

Serum Immunoglobulin Free Light Chain (sFLC) Is a Sensitive Marker of Response in Waldenstrom Macroglobulinemia (WM).

Xavier Leleu, MD, Evdoxia Hatjiharissi, MD, Aldo M. Roccaro, MD, Anne-Sophie Moreau, MD, Renee Leduc, Marybeth Nelson, Mena Farag, Steven P. Treon, MD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2007) 110 (11): 1486.
https://doi.org/10.1182/blood.V110.11.1486.1486
Published: 2007