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Daniel R. Carrasco
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Journal Articles

Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma

Yu-Tzu Tai, Betty Y. Chang, Sun-Young Kong, Mariateresa Fulciniti, Guang Yang, Yolanda Calle, Yiguo Hu, Jianhong Lin, Jian-Jun Zhao, Antonia Cagnetta, Michele Cea, Michael A. Sellitto, Mike Y. Zhong, Qiuju Wang, Chirag Acharya, Daniel R. Carrasco, Joseph J. Buggy, Laurence Elias, Steven P. Treon, William Matsui, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Blood
Blood (2012) 120 (9): 1877–1887.
https://doi.org/10.1182/blood-2011-12-396853
Published: 2012
Includes: Supplemental data
Journal Articles

A proto-oncogene BCL6 is up-regulated in the bone marrow microenvironment in multiple myeloma cells

Brief Report
Teru Hideshima, Constantine Mitsiades, Hiroshi Ikeda, Dharminder Chauhan, Noopur Raje, Gullu Gorgun, Hiromasa Hideshima, Nikhil C. Munshi, Paul G. Richardson, Daniel R. Carrasco, Kenneth C. Anderson
Journal: Blood
Blood (2010) 115 (18): 3772–3775.
https://doi.org/10.1182/blood-2010-02-270082
Published: 2010
Includes: Supplemental data
Journal Articles

Bcl6 as a Novel Therapeutic Target in Multiple Myeloma (MM).

Teru Hideshima, M.D., Ph.D., Constantine S. Mitsiades, MD, PhD, Hiroshi Ikeda, MD, PhD, Dharminder Chauhan, PhD, Noopur Raje, M.D., Gullu Gorgun, PhD, Mariateresa Fulciniti, PhD, Diana Cirstea, MD, Giulia Perron, MD, Loredana Santo, M.D., Ayaka Hideshima, Klaus Podar, MD, MSc, PhD, Nikhil C. Munshi, MD, Paul Richardson, M.D., Ph.D., Daniel R. Carrasco, MD, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2009) 114 (22): 295.
https://doi.org/10.1182/blood.V114.22.295.295
Published: 2009
Journal Articles

A NOVEL Aurora A Kinase INHIBITOR MLN8237 Induces Cytotoxicity and CELL Cycle Arrest IN MULTIPLE MYELOMA.

Gullu Gorgun, PhD, Elisabetta Calabrese, MD, Teru Hideshima, MD, PhD, Jeffrey Ecsedy, PhD, Giada Bianchi, MD, Mala Mani, PhD, Madhavi Bandi, Hiroshi Ikeda, MD, PhD, Giulia Perrone, MD, Yiguo Hu, MD, PhD, Yu-Tzu Tai, PhD, Mei Zheng, Diana Cristea, MD, Loredana Santo, MD, Daniel R. Carrasco, MD, PhD, Nikhil Munshi, MD, Paul Richardson, MD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2009) 114 (22): 3830.
https://doi.org/10.1182/blood.V114.22.3830.3830
Published: 2009
Journal Articles

Aurora kinase A is a target of Wnt/β-catenin involved in multiple myeloma disease progression

Jui Dutta-Simmons, Yunyu Zhang, Gullu Gorgun, Moshe Gatt, Mala Mani, Teru Hideshima, Kohichi Takada, Nicole E. Carlson, Daniel E. Carrasco, Yu-Tzu Tai, Noopur Raje, Anthony G. Letai, Kenneth C. Anderson, Daniel R. Carrasco
Journal: Blood
Blood (2009) 114 (13): 2699–2708.
https://doi.org/10.1182/blood-2008-12-194290
Published: 2009
Includes: Supplemental data
Journal Articles

CS1 Promotes Multiple Myeloma Cell Adhesion, Clonogenic Growth, and Tumorigenicity Via C-Maf-Mediated Interactions with Bone Marrow Stromal Cells (BMSCs)

Yu-Tzu Tai, PhD, Ender Soydan, Mariateresa Fulciniti, Weihua Song, Xian-Feng Li, Peter Burger, Fangxin Hong, Giovanni Tonon, Kihyun Kim, Mathew J. Rumizen, Sabikun Nahar, Klaus Podar, Dharminder Chauhan, Teru Hideshima, Daniel R. Carrasco, Nikhil C Munshi, Daniel Afar, PhD, Kenneth C. Anderson
Journal: Blood
Blood (2008) 112 (11): 840.
https://doi.org/10.1182/blood.V112.11.840.840
Published: 2008
Journal Articles

RFP2 Knockdown Disrupts Cell Growth and Induces Apoptosis in Multiple Myeloma

Moshe E. Gatt, MD, Mala Mani, PhD, Jui Dutta, PhD, Daniel E. Carrasco, John D Shaughnessy, Jr., PhD, Kenneth C. Anderson, MD, Daniel R Carrasco, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 5327.
https://doi.org/10.1182/blood.V112.11.5327.5327
Published: 2008
Journal Articles

Targeting NF-κB in Waldenstrom macroglobulinemia

Xavier Leleu, Jérôme Eeckhoute, Xiaoying Jia, Aldo M. Roccaro, Anne-Sophie Moreau, Mena Farag, Antonio Sacco, Hai T. Ngo, Judith Runnels, Molly R. Melhem, Nicolas Burwick, Abdelkareem Azab, Feda Azab, Zachary Hunter, Evdoxia Hatjiharissi, Daniel R. Carrasco, Steven P. Treon, Thomas E. Witzig, Teru Hideshima, Myles Brown, Kenneth C. Anderson, Irene M. Ghobrial
Journal: Blood
Blood (2008) 111 (10): 5068–5077.
https://doi.org/10.1182/blood-2007-09-115170
Published: 2008
Journal Articles

Genome-Wide Profiling of Endothelial Progenitor Cells in Multiple Myeloma: Overlaps with Myeloma Tumor Cells and Common Cancer Gene-Pathways.

Marc J. Braunstein, Daniel R. Carrasco, Fabien Campagne, Piali Mukherjee, Kumar Sukhdeo, Alexei Protopopov, Kenneth C. Anderson, Olcay A. Batuman
Journal: Blood
Blood (2007) 110 (11): 394.
https://doi.org/10.1182/blood.V110.11.394.394
Published: 2007
Journal Articles

ß-Catenin Is a Novel Marker of the Aggresome and Suggests Disruption of the Proteasome-Aggresome-Autophagasome Pathway in Multiple Myeloma In Vivo.

Kumar Sukhdeo, Mei Zheng, Teru Hideshima, MD,PhD, Kenneth C. Anderson, MD, Daniel R. Carrasco, MD,PhD
Journal: Blood
Blood (2006) 108 (11): 3449.
https://doi.org/10.1182/blood.V108.11.3449.3449
Published: 2006
Journal Articles

Clonotypic Bone Marrow-Derived Endothelial Progenitor Cells in Multiple Myeloma.

Marc J. Braunstein, MD, PhD, Daniel R. Carrasco, MD,PhD, David Kahn, MD, Kumar Sukhdeo, PhD, Alexei Protopopov, PhD, Yunyu Zhang, Kenneth C. Anderson, MD, Olcay Batuman, MD
Journal: Blood
Blood (2006) 108 (11): 3497.
https://doi.org/10.1182/blood.V108.11.3497.3497
Published: 2006
Journal Articles

Novel Model To Evaluate Changes in Gene Expression Profile of Myeloma Cells In Vivo Following Interaction with Human BM Microenvironment.

Paola Neri, MD, Pierfrancesco Tassone, MD, Masood A. Shammas, PhD, Daniel R. Carrasco, MD, Renate Burger, PhD, Constantine S. Mitsdiades, MD, Simona Blotta, MD, Rao H. Prabhala, PhD, Laurence Catley, MD, Salvatore Venuta, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2005) 106 (11): 2490.
https://doi.org/10.1182/blood.V106.11.2490.2490
Published: 2005
Journal Articles

Alkylphosphocholine Perifosine Inhibits Myeloma Cell Growth While Inducing Myeloid Hyperplasia in a Murine Myeloma Model.

Laurence Catley, MBBS, FRACP, FRCPA, Teru Hideshima, MD, PhD, Dharminder Chauhan, JD, PhD, Paola Neri, MD, Piefrancesco Tassone, MD, Yu-Tzu Tai, PhD, Weihua Song, MD, Daniel R. Carrasco, MD, PhD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2005) 106 (11): 1579.
https://doi.org/10.1182/blood.V106.11.1579.1579
Published: 2005
Journal Articles

A clinically relevant SCID-hu in vivo model of human multiple myeloma

Pierfrancesco Tassone, Paola Neri, Daniel R. Carrasco, Renate Burger, Victor S. Goldmacher, Robert Fram, Vidit Munshi, Masood A. Shammas, Laurence Catley, Gary S. Jacob, Salvatore Venuta, Kenneth C. Anderson, Nikhil C. Munshi
Journal: Blood
Blood (2005) 106 (2): 713–716.
https://doi.org/10.1182/blood-2005-01-0373
Published: 2005
Journal Articles

Cytotoxic activity of the maytansinoid immunoconjugate B-B4–DM1 against CD138 + multiple myeloma cells

Pierfrancesco Tassone, Victor S. Goldmacher, Paola Neri, Antonella Gozzini, Masood A. Shammas, Kathleen R. Whiteman, Linda L. Hylander-Gans, Daniel R. Carrasco, Teru Hideshima, Reshma Shringarpure, Jialan Shi, Charles K. Allam, John Wijdenes, Salvatore Venuta, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Blood
Blood (2004) 104 (12): 3688–3696.
https://doi.org/10.1182/blood-2004-03-0963
Published: 2004
Journal Articles

A Clinically Relevant SCID-hu in Vivo Model of Human Multiple Myeloma.

Pierfrancesco Tassone, MD, Paola Neri, MD, Daniel R. Carrasco, MD, Renate Burger, PhD, Laurence Catley, MD, Salvatore Venuta, MD, PhD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2004) 104 (11): 2455.
https://doi.org/10.1182/blood.V104.11.2455.2455
Published: 2004