Page 1 | Search Results | Blood | American Society of Hematology

1-16 of 16

Sort by

Sort Order Select

Journal Articles

Inhibition Of PI3K Classia Kinases Using GDC0941 Overcomes Protection Of Multiple Myeloma Cells In The Bone Marrow Microenvironment

Hugh Kikuchi, BSc, Amofa Eunice, PhD, Maeve McEnery, BSc, Farzin Farzaneh, DPhil, Stephen A Schey, MD, Yolanda Calle, PhD

Blood (2013) 122 (21): 3169.

https://doi.org/10.1182/blood.V122.21.3169.3169

Published: 2013

Journal Articles

Absence Of Mutation In Cereblon (CRBN) and DNA Damage Binding Protein 1 (DDB1) Genes In Myeloma Cells and Patients and Its Clinical Significance

Anjan Thakurta, PhD, Anita K Gandhi, PhD, Michelle Waldman, MS, Chad C. Bjorklund, Ph.D., Suzanne Lentzsch, MD, PhD, Stephen A Schey, MD, Yolanda Calle, PhD, Rajani Chelliah, BSc, MSc, Robert Z. Orlowski, M.D., Ph.D, Anup Madan, PhD, Yuhong Ning, Derek Mendy, B.S., Antonia Lopez-Girona, PhD, Peter H Schafer, PhD, Herve Avet-Loiseau, MD, Rajesh Chopra, MD

Blood (2013) 122 (21): 3139.

https://doi.org/10.1182/blood.V122.21.3139.3139

Published: 2013

Journal Articles

CRM1 Blockade by Novel Inhibitors of Nuclear Export (SINEs) Inhibits Multiple Myeloma Cell Growth, Osteoclastogenesis, and Myeloma-Induced Osteolysis

Blood (2012) 120 (21): 326.

https://doi.org/10.1182/blood.V120.21.326.326

Published: 2012

Journal Articles

Beta7 Integrins Regulate Podia Formation in Multiple Myeloma (MM) Cells for the Interaction with the Cellular and Non-Cellular Bone Marrow (BM) Stroma

Karthik Ramasamy, MBBS, MRCP, FRCPath, Henry Lekgetho, Mr, Jose Luis Orgaz, Dr, Amna Anwar, BSc, Victoria Sanz-Moreno, Dr, Majid A Kazmi, Stephen Schey, MD, Yolanda Calle, PhD

Blood (2012) 120 (21): 3979.

https://doi.org/10.1182/blood.V120.21.3979.3979

Published: 2012

Journal Articles

CRM1 Inhibition Abrogates Osteoclast Formation and Bone Resorption Via Inhibition of RANKL-Induced NFκB While Sparing Osteoblastogenesis: Further Therapeutic Implication in Multiple Myeloma

Chirag Acharya, MD, Mike Y Zhong, B.S., Yolanda Calle, PhD, Stephen Schey, MD, Michelle Chen, Daniel Tannenbaum, B.S., Michaela R Reagan, PhD, Irene M. Ghobrial, MD, Yosef Landesman, PhD, Sharon Shacham, PhD MBA, Michael Kauffman, MD, PhD, Kenneth C. Anderson, MD, Yu-Tzu Tai, PhD

Blood (2012) 120 (21): 1835.

https://doi.org/10.1182/blood.V120.21.1835.1835

Published: 2012

Journal Articles

Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma

Blood (2012) 120 (9): 1877–1887.

https://doi.org/10.1182/blood-2011-12-396853

Published: 2012

Includes: Supplemental data

Journal Articles

Podia in Multiple Myeloma (MM) Cells Promote Adhesion with Bone Marrow (BM) Fibroblastic Stromal Cells

Karthik Ramasamy, MBBS, MRCP, FRCPath, Amna Anwar, BSc, Majid A. Kazmi, Steve Schey, Yolanda Calle, PhD

Blood (2011) 118 (21): 626.

https://doi.org/10.1182/blood.V118.21.626.626

Published: 2011

Journal Articles

Targeting Brouton's Tyrosine Kinase with PCI-32765 Blocks Growth and Survival of Multiple Myeloma and Waldenström Macroglobulinemia Via Potent Inhibition of Osteoclastogenesis, Cytokines/Chemokine Secretion, and Myeloma Stem-Like Cells in the Bone Marrow Microenvironment

Blood (2011) 118 (21): 883.

https://doi.org/10.1182/blood.V118.21.883.883

Published: 2011

Journal Articles

The Wiskott Aldrich Syndrome Protein (WASP) Is Involved in Dexamethasone-Signalling Pathways Leading to Apoptosis of Multiple Myeloma Cells and in Cell Adhesion Mediated Drug Resistance Against Dexamethasone

Hazera Khatun, Amna Anwar, BSc, Majid A. Kazmi, Stephen Schey, Yolanda Calle, PhD

Blood (2011) 118 (21): 1809.

https://doi.org/10.1182/blood.V118.21.1809.1809

Published: 2011

Journal Articles

Direct Effect on the Stroma by the Conventional Anti-Multiple Myeloma Drug Dexamethasone Results In Resistance of Multiple Myeloma Plasma Cells Against Therapy. Sensitisation to Dexamethasone by the Kinase Inhibitor Dasatinib

Karthik Ramasamy, MBBS, MRCP, FRCPath, Hazera Khatun, Lee Macpherson, Ghulam J. Mufti, DM, FRCP, FRCPath, Stephen Schey, MBBS, Yolanda Calle

Blood (2010) 116 (21): 1931.

https://doi.org/10.1182/blood.V116.21.1931.1931

Published: 2010

Journal Articles

Tyrosine Phosphorylation of WASP Promotes Calpain-Mediated Podosome Disassembly In Myeloid Cells.

Lee Macpherson, James Monypenny, Michael P Blundell, Giles O Cory, Jessica Tomé-García, Adrian Thrasher, Gareth E Jones, Yolanda Calle

Blood (2010) 116 (21): 1498.

https://doi.org/10.1182/blood.V116.21.1498.1498

Published: 2010

Journal Articles

Novel In Vitro Experimental Platform for High Throughput Analysis of the Effect of Drugs on Multiple Myeloma Cells and the Tumour Microenvironment In a Co-Culture Setting

Karthik Ramasamy, MBBS, MRCP, FRCPath, Hazera Khatun, Lee Macpherson, Stephen Schey, MBBS, Yolanda Calle

Blood (2010) 116 (21): 982.

https://doi.org/10.1182/blood.V116.21.982.982

Published: 2010

Journal Articles

Dual Src/Abl Kinase Targeted Inhibition in Myeloma Microenvironment Promotes Myeloma Cell Apoptosis Both in Vitro and In Vivo .

Karthik Ramasamy, Lee Macpherson, Ghulam J Mufti, MBBS, DM, FRCP, FRCPath, Stephen Schey, Yolanda Calle, Ph.D.

Blood (2009) 114 (22): 2813.

https://doi.org/10.1182/blood.V114.22.2813.2813

Published: 2009

Journal Articles

Hepatocyte Growth Factor Expression in Bone Marrow Microenvironment Is Critical for Progression of MGUS to Myeloma.

Karthik Ramasamy, MD, Stephen Schey, MD, Ghulam J. Mufti, MD, DM, Farzin Farzaneh, PhD, Yolanda Calle, PhD

Blood (2007) 110 (11): 4766.

https://doi.org/10.1182/blood.V110.11.4766.4766

Published: 2007

Journal Articles

Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia

Phil J. Ancliff, Michael P. Blundell, Giles O. Cory, Yolanda Calle, Austen Worth, Helena Kempski, Siobhan Burns, Gareth E. Jones, Jo Sinclair, Christine Kinnon, Ian M. Hann, Rosemary E. Gale, David C. Linch, Adrian J. Thrasher

Blood (2006) 108 (7): 2182–2189.

https://doi.org/10.1182/blood-2006-01-010249

Published: 2006

Includes: Multimedia, Supplemental data

Journal Articles

WASp deficiency in mice results in failure to form osteoclast sealing zones and defects in bone resorption

Yolanda Calle, Gareth E. Jones, Chris Jagger, Karen Fuller, Mike P. Blundell, Jade Chow, Tim Chambers, Adrian J. Thrasher

Blood (2004) 103 (9): 3552–3561.

https://doi.org/10.1182/blood-2003-04-1259

Published: 2004

Includes: Multimedia, Supplemental data

NARROW

Inhibition Of PI3K Classia Kinases Using GDC0941 Overcomes Protection Of Multiple Myeloma Cells In The Bone Marrow Microenvironment

Absence Of Mutation In Cereblon (CRBN) and DNA Damage Binding Protein 1 (DDB1) Genes In Myeloma Cells and Patients and Its Clinical Significance

CRM1 Blockade by Novel Inhibitors of Nuclear Export (SINEs) Inhibits Multiple Myeloma Cell Growth, Osteoclastogenesis, and Myeloma-Induced Osteolysis

Beta7 Integrins Regulate Podia Formation in Multiple Myeloma (MM) Cells for the Interaction with the Cellular and Non-Cellular Bone Marrow (BM) Stroma

CRM1 Inhibition Abrogates Osteoclast Formation and Bone Resorption Via Inhibition of RANKL-Induced NFκB While Sparing Osteoblastogenesis: Further Therapeutic Implication in Multiple Myeloma

Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma

Podia in Multiple Myeloma (MM) Cells Promote Adhesion with Bone Marrow (BM) Fibroblastic Stromal Cells

Targeting Brouton's Tyrosine Kinase with PCI-32765 Blocks Growth and Survival of Multiple Myeloma and Waldenström Macroglobulinemia Via Potent Inhibition of Osteoclastogenesis, Cytokines/Chemokine Secretion, and Myeloma Stem-Like Cells in the Bone Marrow Microenvironment

The Wiskott Aldrich Syndrome Protein (WASP) Is Involved in Dexamethasone-Signalling Pathways Leading to Apoptosis of Multiple Myeloma Cells and in Cell Adhesion Mediated Drug Resistance Against Dexamethasone

Direct Effect on the Stroma by the Conventional Anti-Multiple Myeloma Drug Dexamethasone Results In Resistance of Multiple Myeloma Plasma Cells Against Therapy. Sensitisation to Dexamethasone by the Kinase Inhibitor Dasatinib

Tyrosine Phosphorylation of WASP Promotes Calpain-Mediated Podosome Disassembly In Myeloid Cells.

Novel In Vitro Experimental Platform for High Throughput Analysis of the Effect of Drugs on Multiple Myeloma Cells and the Tumour Microenvironment In a Co-Culture Setting

Dual Src/Abl Kinase Targeted Inhibition in Myeloma Microenvironment Promotes Myeloma Cell Apoptosis Both in Vitro and In Vivo .

Hepatocyte Growth Factor Expression in Bone Marrow Microenvironment Is Critical for Progression of MGUS to Myeloma.

Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia

WASp deficiency in mice results in failure to form osteoclast sealing zones and defects in bone resorption

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only