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Darrin M. Beaupre
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Journal Articles

The Pan-Clk/Dyrk Inhibitor Cirtuvivint (SM08502) Exposes Mechanistic Underpinnings of Alternative Splicing As a Therapeutic Vulnerability in Heme Malignancies

Free
Carine Bossard, Elizabeth A. McMillan, Emily Creger, Brian Eastman, Chi-Ching Mak, Darrin M. Beaupre, Michael A. White
Journal: Blood
Blood (2021) 138 (Supplement 1): 2950.
https://doi.org/10.1182/blood-2021-151305
Published: 2021
Journal Articles

Ibrutinib plus lenalidomide and rituximab has promising activity in relapsed/refractory non–germinal center B-cell–like DLBCL

Free
Clinical Trials & Observations
Andre Goy, Radhakrishnan Ramchandren, Nilanjan Ghosh, Javier Munoz, David S. Morgan, Nam H. Dang, Mark Knapp, Maria Delioukina, Edwin Kingsley, Jerry Ping, Darrin M. Beaupre, Jutta K. Neuenburg, Jia Ruan
Journal: Blood
Blood (2019) 134 (13): 1024–1036.
https://doi.org/10.1182/blood.2018891598
Published: 2019
Includes: Supplemental data
Journal Articles

Targeting Bruton tyrosine kinase with ibrutinib in relapsed/refractory marginal zone lymphoma

Free
Clinical Trials & Observations
Ariela Noy, Sven de Vos, Catherine Thieblemont, Peter Martin, Christopher R. Flowers, Franck Morschhauser, Graham P. Collins, Shuo Ma, Morton Coleman, Shachar Peles, Stephen Smith, Jacqueline C. Barrientos, Alina Smith, Brian Munneke, Isaiah Dimery, Darrin M. Beaupre, Robert Chen
Journal: Blood
Blood (2017) 129 (16): 2224–2232.
https://doi.org/10.1182/blood-2016-10-747345
Published: 2017
Includes: Supplemental data
Journal Articles

A Multicenter Open-Label, Phase 1b/2 Study of Ibrutinib in Combination with Lenalidomide and Rituximab in Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

Free
Andre Goy, MD, Radhakrishnan Ramchandren, MD, Nilanjan Ghosh, MD PhD, Javier Munoz, MD, David S. Morgan, MD, Nam H. Dang, MD PhD, Mark Knapp, MD, Maria Delioukina, MD, Edwin C. Kingsley, MD, Anh Tran, BS, Jerry Ping, PhD, Darrin M. Beaupre, MD PhD, Jutta K. Neuenburg, MD PhD, Jia Ruan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 473.
https://doi.org/10.1182/blood.V128.22.473.473
Published: 2016
Journal Articles

Ibrutinib Combined with Rituximab in Treatment-Naive Patients with Follicular Lymphoma: Arm 1 + Arm 2 Results from a Multicenter, Open-Label Phase 2 Study

Free
Nathan Fowler, MD, Loretta Nastoupil, MD, Sven de Vos, MD PhD, Mark Knapp, MD, Ian W. Flinn, MD PhD, Robert W Chen, MD, Ranjana H Advani, MD, Sumeet Bhatia, MD, Peter Martin, MD, Raul Mena, MD, Samuel Suzuki, MS, MBA, Darrin M. Beaupre, MD PhD, Jutta K. Neuenburg, MD PhD, M. Lia Palomba, MD
Journal: Blood
Blood (2016) 128 (22): 1804.
https://doi.org/10.1182/blood.V128.22.1804.1804
Published: 2016
Journal Articles

Ibrutinib Plus Rituximab in Treatment-Naive Patients with Follicular Lymphoma: Results from a Multicenter, Phase 2 Study

Free
Nathan Fowler, MD, Loretta Nastoupil, MD, Sven de Vos, MD PhD, Mark Knapp, MD, Ian W. Flinn, MD PhD, Robert Chen, Ranjana H Advani, MD, Sumeet Bhatia, MD, Peter Martin, MD, Raul Mena, MD, Samuel Suzuki, MS, MBA, Darrin M. Beaupre, MD, Jutta K. Neuenburg, MD, M. Lia Palomba, MD
Journal: Blood
Blood (2015) 126 (23): 470.
https://doi.org/10.1182/blood.V126.23.470.470
Published: 2015
Journal Articles

Long-term follow-up of MCL patients treated with single-agent ibrutinib: updated safety and efficacy results

Free
Clinical Trials & Observations
Michael L. Wang, Kristie A. Blum, Peter Martin, Andre Goy, Rebecca Auer, Brad S. Kahl, Wojciech Jurczak, Ranjana H. Advani, Jorge E. Romaguera, Michael E. Williams, Jacqueline C. Barrientos, Ewa Chmielowska, John Radford, Stephan Stilgenbauer, Martin Dreyling, Wieslaw Wiktor Jedrzejczak, Peter Johnson, Stephen E. Spurgeon, Liang Zhang, Linda Baher, Mei Cheng, Dana Lee, Darrin M. Beaupre, Simon Rule
Journal: Blood
Blood (2015) 126 (6): 739–745.
https://doi.org/10.1182/blood-2015-03-635326
Published: 2015
Includes: Supplemental data
Journal Articles

Single-Agent Ibrutinib Demonstrates Safety and Durability of Response at 2 Years Follow-up in Patients with Relapsed or Refractory Mantle Cell Lymphoma: Updated Results of an International, Multicenter, Open-Label Phase 2 Study

Free
Michael Wang, MD, Simon Rule, MD, Peter Martin, MD, Andre Goy, MD, Rebecca Auer, MD PhD, Brad S. Kahl, MD, Wojciech Jurczak, Ranjana Advani, MD, Jorge E. Romaguera, MD, Michael E. Williams, MD, Jacqueline C. Barrientos, MD, Ewa Chmielowska, MD, John Radford, Stephan Stilgenbauer, MD, Martin Dreyling, Wieslaw Wiktor Jedrzejczak, MD, Peter W Johnson, MD, Stephen E. Spurgeon, MD, Liang Zhang, MD PhD, Linda Baher, Mei Cheng, PhD, Darrin M. Beaupre, MD, Kristie A. Blum, MD
Journal: Blood
Blood (2014) 124 (21): 4453.
https://doi.org/10.1182/blood.V124.21.4453.4453
Published: 2014
Journal Articles

Safety and Tolerability of Conatumumab in Combination with Bortezomib or Vorinostat in Patients with Relapsed or Refractory Lymphoma.

Free
Anas Younes, MD, Mark Kirschbaum, MD, Lubomir Sokol, MD, PhD, Lorrin Yee, Jorge Romaguera, MD, Lovely Goyal, Cheng-Pang Hsu, Yuying Hwang, Kevin Gorski, Susan Wong, Darrin M. Beaupre, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1708.
https://doi.org/10.1182/blood.V114.22.1708.1708
Published: 2009
Journal Articles

Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells

Free
Kuichun Zhu, Elvira Gerbino, Darrin M. Beaupre, Paul A. Mackley, Carlos Muro-Cacho, Craig Beam, Andrew D. Hamilton, Mathias G. Lichtenheld, William G. Kerr, William Dalton, Melissa Alsina, Saïd M. Sebti
Journal: Blood
Blood (2005) 105 (12): 4759–4766.
https://doi.org/10.1182/blood-2004-11-4307
Published: 2005
Journal Articles

Characterization of a R115777 Resistant Human Multiple Myeloma Cell Line with Cross-Resistance to PS-341.

Free
Robert W. Buzzeo, BS, Steven A. Enkemann, PhD, Ramadevi Nimmanapalli, PhD, Melissa Alsina, MD, Mathias G. Lichtenheld, MD, William S. Dalton, MD, PhD, Darrin M. Beaupre, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 3363.
https://doi.org/10.1182/blood.V104.11.3363.3363
Published: 2004