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Journal Articles

Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk

Wenli Liu, Joachim Pircher, Art Schuermans, Qurrat Ul Ain, Zhe Zhang, Michael C. Honigberg, Mustafa Yalcinkaya, Tetsushi Nakao, Ashley Pournamadri, Tong Xiao, Mohammad Ali Hajebrahimi, Lisa Wasner, David Stegner, Tobias Petzold, Pradeep Natarajan, Steffen Massberg, Alan R. Tall, Christian Schulz, Nan Wang

Blood (2024) 143 (15): 1539–1550.

https://doi.org/10.1182/blood.2023022260

Published: 2024

Includes: Multimedia, Supplemental data

Journal Articles

The bone marrow is the primary site of thrombopoiesis

Nathan L. Asquith, Estelle Carminita, Virginia Camacho, Antonio Rodriguez-Romera, David Stegner, Daniela Freire, Isabelle C. Becker, Kellie R. Machlus, Abdullah O. Khan, Joseph E. Italiano

Blood (2024) 143 (3): 272–278.

https://doi.org/10.1182/blood.2023020895

Published: 2024

Includes: Supplemental data

Journal Articles

XPoRting (poly)phosphates limits thrombosis

David Stegner, Bernhard Nieswandt

Blood (2021) 137 (10): 1278–1280.

https://doi.org/10.1182/blood.2020008973

Published: 2021

Journal Articles

Platelet glycoprotein VI promotes metastasis through interaction with cancer cell–derived galectin-3

Elmina Mammadova-Bach, Jesus Gil-Pulido, Edita Sarukhanyan, Philipp Burkard, Sergey Shityakov, Charlotte Schonhart, David Stegner, Katharina Remer, Paquita Nurden, Alan T. Nurden, Thomas Dandekar, Laszlo Nehez, Magdolna Dank, Attila Braun, Diego Mezzano, Scott I. Abrams, Bernhard Nieswandt

Blood (2020) 135 (14): 1146–1160.

https://doi.org/10.1182/blood.2019002649

Published: 2020

Includes: Supplemental data

Journal Articles

Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis

Blood (2019) 134 (21): 1847–1858.

https://doi.org/10.1182/blood.2019000185

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

Spatial Regulation of Thrombopoiesis in the Bone Marrow

David Stegner, PhD, Judith van Eeuwijk, PhD, Maximilian G Gorelashvili, Oguzhan Angay, Mike Friedrich, Jürgen Pinnecker, Patrick Schmithausen, Daniela Semeniak, PhD, Harald Schulze, PhD, Christian Brede, PhD, Andreas Beilhack, MD, Bernhard Nieswandt, PhD, Katrin G Heinze

Blood (2018) 132 (Supplement 1): SCI-23.

https://doi.org/10.1182/blood-2018-99-109545

Published: 2018

Journal Articles

ADAP deficiency impairs megakaryocyte polarization with ectopic proplatelet release and causes microthrombocytopenia

Markus Spindler, Judith M. M. van Eeuwijk, Yvonne Schurr, Paquita Nurden, Bernhard Nieswandt, David Stegner, Annegret Reinhold, Markus Bender

Blood (2018) 132 (6): 635–646.

https://doi.org/10.1182/blood-2018-01-829259

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

CK2β regulates thrombopoiesis and Ca 2+ -triggered platelet activation in arterial thrombosis

Blood (2017) 130 (25): 2774–2785.

https://doi.org/10.1182/blood-2017-05-784413

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

CLEC-2 contributes to hemostasis independently of classical hemITAM signaling in mice

Elizabeth J. Haining, Deya Cherpokova, Karen Wolf, Isabelle C. Becker, Sarah Beck, Johannes A. Eble, David Stegner, Steve P. Watson, Bernhard Nieswandt

Blood (2017) 130 (20): 2224–2228.

https://doi.org/10.1182/blood-2017-03-771907

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

Platelet secretion is crucial to prevent bleeding in the ischemic brain but not in the inflamed skin or lung in mice

Carsten Deppermann, Peter Kraft, Julia Volz, Michael K. Schuhmann, Sarah Beck, Karen Wolf, David Stegner, Guido Stoll, Bernhard Nieswandt

Blood (2017) 129 (12): 1702–1706.

https://doi.org/10.1182/blood-2016-12-750711

Published: 2017

Includes: Supplemental data

Journal Articles

FcγRIIB on liver sinusoidal endothelial cells is essential for antibody-induced GPVI ectodomain shedding in mice

David Stegner, Michael Popp, Viola Lorenz, Jacqueline K. Wax, J. Engelbert Gessner, Bernhard Nieswandt

Blood (2016) 128 (6): 862–865.

https://doi.org/10.1182/blood-2016-05-714378

Published: 2016

Includes: Supplemental data

Journal Articles

Targeted downregulation of platelet CLEC-2 occurs through Syk-independent internalization

Viola Lorenz, David Stegner, Simon Stritt, Timo Vögtle, Friedemann Kiefer, Walter Witke, Jürgen Schymeinsky, Steve P. Watson, Barbara Walzog, Bernhard Nieswandt

Blood (2015) 125 (26): 4069–4077.

https://doi.org/10.1182/blood-2014-11-611905

Published: 2015

Includes: Supplemental data

Journal Articles

Aberrant Microtubule Organization and Wiskott-Aldrich Syndrome-like Defects in Platelets and Megakaryocytes of Profilin1-Deficient Mice

Simon Stritt, Markus Bender, Paquita Nurden, MD PhD, Judith van Eeuwijk, Barbara Zieger, Prof, Karim Kentouche, MD, Harald Schulze, Prof, Henner Morbach, MD, David Stegner, PhD, Katrin G Heinze, PhD, Sebastian Dütting, PhD, Shuchi Gupta, PhD, Walter Witke, Prof, Hervé Falet, PhD, Alain Fischer, Prof, John H. Hartwig, Prof, Bernhard Nieswandt, Prof

Blood (2014) 124 (21): 4200.

https://doi.org/10.1182/blood.V124.21.4200.4200

Published: 2014

Journal Articles

Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation

Yasuaki Shida, Natalia Rydz, David Stegner, Christine Brown, Jeffrey Mewburn, Kate Sponagle, Ozge Danisment, Bredon Crawford, Barbara Vidal, Carol A. Hegadorn, Cynthia M. Pruss, Bernhard Nieswandt, David Lillicrap

Blood (2014) 124 (11): 1799–1807.

https://doi.org/10.1182/blood-2013-09-521484

Published: 2014

Journal Articles

Size does matter: VWF in MI

David Stegner, Bernhard Nieswandt

Blood (2012) 120 (26): 5096–5097.

https://doi.org/10.1182/blood-2012-09-452813

Published: 2012

Journal Articles

Differentially regulated GPVI ectodomain shedding by multiple platelet–expressed proteinases

Markus Bender, Sebastian Hofmann, David Stegner, Athena Chalaris, Michael Bösl, Attila Braun, Jürgen Scheller, Stefan Rose-John, Bernhard Nieswandt

Blood (2010) 116 (17): 3347–3355.

https://doi.org/10.1182/blood-2010-06-289108

Published: 2010

Journal Articles

STIM1 is essential for Fcγ receptor activation and autoimmune inflammation

Attila Braun, J. Engelbert Gessner, David Varga-Szabo, Shahzad N. Syed, Stephanie Konrad, David Stegner, Timo Vögtle, Reinhold E. Schmidt, Bernhard Nieswandt

Blood (2009) 113 (5): 1097–1104.

https://doi.org/10.1182/blood-2008-05-158477

Published: 2009

Includes: Supplemental data

NARROW

Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk

The bone marrow is the primary site of thrombopoiesis

XPoRting (poly)phosphates limits thrombosis

Platelet glycoprotein VI promotes metastasis through interaction with cancer cell–derived galectin-3

Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis

Spatial Regulation of Thrombopoiesis in the Bone Marrow

ADAP deficiency impairs megakaryocyte polarization with ectopic proplatelet release and causes microthrombocytopenia

CK2β regulates thrombopoiesis and Ca 2+ -triggered platelet activation in arterial thrombosis

CLEC-2 contributes to hemostasis independently of classical hemITAM signaling in mice

Platelet secretion is crucial to prevent bleeding in the ischemic brain but not in the inflamed skin or lung in mice

FcγRIIB on liver sinusoidal endothelial cells is essential for antibody-induced GPVI ectodomain shedding in mice

Targeted downregulation of platelet CLEC-2 occurs through Syk-independent internalization

Aberrant Microtubule Organization and Wiskott-Aldrich Syndrome-like Defects in Platelets and Megakaryocytes of Profilin1-Deficient Mice

Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation

Size does matter: VWF in MI

Differentially regulated GPVI ectodomain shedding by multiple platelet–expressed proteinases

STIM1 is essential for Fcγ receptor activation and autoimmune inflammation

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American Society of Hematology

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ASH Publications

American Society of Hematology

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