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Derek A West
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Journal Articles

Silencing of the inhibitor of DNA binding protein 4 (ID4) contributes to the pathogenesis of mouse and human CLL

Shih-Shih Chen, Rainer Claus, David M. Lucas, Lianbo Yu, Jiang Qian, Amy S. Ruppert, Derek A. West, Katie E. Williams, Amy J. Johnson, Fred Sablitzky, Christoph Plass, John C. Byrd
Journal: Blood
Blood (2011) 117 (3): 862–871.
https://doi.org/10.1182/blood-2010-05-284638
Published: 2011
Includes: Supplemental data
Journal Articles

17-DMAG targets the nuclear factor-κB family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition

Erin Hertlein, Amy J. Wagner, Jeffrey Jones, Thomas S. Lin, Kami J. Maddocks, William H. Towns, III, Virginia M. Goettl, Xiaoli Zhang, David Jarjoura, Chelsey A. Raymond, Derek A. West, Carlo M. Croce, John C. Byrd, Amy J. Johnson
Journal: Blood
Blood (2010) 116 (1): 45–53.
https://doi.org/10.1182/blood-2010-01-263756
Published: 2010
Includes: Supplemental data
Journal Articles

The HSP90 Inhibitor 17-DMAG Targets NF-κB to Induce Apoptosis in CLL and Prolongs Survival in a CLL Mouse Model.

Erin K Hertlein, PhD, Thomas S Lin, MD, PhD, Wagner J Amy, Towns H William, II, Virginia M Goettl, Xiaoli Zhang, David Jarjoura, Chelsey A Raymond, Derek A West, John C. Byrd, MD, Amy J. Johnson, PhD
Journal: Blood
Blood (2009) 114 (22): 732.
https://doi.org/10.1182/blood.V114.22.732.732
Published: 2009
Journal Articles

The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo

David M. Lucas, Ryan B. Edwards, Gerard Lozanski, Derek A. West, Jungook D. Shin, Melissa A. Vargo, Melanie E. Davis, Darlene M. Rozewski, Amy J. Johnson, Bao-Ning Su, Virginia M. Goettl, Nyla A. Heerema, Thomas S. Lin, Amy Lehman, Xiaoli Zhang, David Jarjoura, David J. Newman, John C. Byrd, A. Douglas Kinghorn, Michael R. Grever
Journal: Blood
Blood (2009) 113 (19): 4656–4666.
https://doi.org/10.1182/blood-2008-09-175430
Published: 2009
Journal Articles

17-DMAG Targets the NF-κB Family of Proteins to Induce Apoptosis in CLL: Clinical Implications of Hsp90 Inhibition

Amy J Wagner, Erin K Hertlein, PhD, Chelsey A Raymond, Derek A West, Joseph M Flynn, DO, MPH, Thomas Lin, MD, PhD, Amy J Johnson, PhD, John C Byrd, MD
Journal: Blood
Blood (2008) 112 (11): 381.
https://doi.org/10.1182/blood.V112.11.381.381
Published: 2008
Journal Articles

NF-κB Is Active in Mcl-1 Promoter Regulation in Human CLL.

Erin K Hertlein, PhD, Derek A. West, Ruth W Craig, PhD, David M Lucas, PhD, John C. Byrd, MD
Journal: Blood
Blood (2008) 112 (11): 2265.
https://doi.org/10.1182/blood.V112.11.2265.2265
Published: 2008
Journal Articles

The Plant-Derived Agent Silvestrol Has B-Cell Selective Activity In Vitro in Chronic Lymphocytic Leukemia Patient Cells and In Vivo in the Tcl-1 Mouse Model of CLL.

David M. Lucas, PhD, Ryan B. Edwards, Michael D. De Lay, Derek A. West, Gerard Lozanski, MD, Amy J. Johnson, PhD, Angela A. Salim, PhD, Thomas S. Lin, MD, PhD, John C. Byrd, MD, A. Douglas Kinghorn, PhD, Michael R. Grever, MD
Journal: Blood
Blood (2007) 110 (11): 3123.
https://doi.org/10.1182/blood.V110.11.3123.3123
Published: 2007
Journal Articles

The Novel Histone Deacetylase Inhibitor OSU-HDAC42 Has Class I and II Histone Deacetylase (HDAC) Inhibitory Activity and Represents a Novel Therapy for Chronic Lymphocytic Leukemia.

Derek A. West, BS, David M. Lucas, PhD, Melanie E. Davis, PhD, Michael D. De Lay, BA, Amy J. Johnson, PhD, Sara E. Guster, MS/MBA, Michael A. Freitas, PhD, Mark R. Parthun, PhD, Dasheng Wang, PhD, Samuel K. Kulp, PhD/DVM, Michael R. Grever, MD, Ching-Shih Chen, PhD, John C. Byrd, MD
Journal: Blood
Blood (2006) 108 (11): 2807.
https://doi.org/10.1182/blood.V108.11.2807.2807
Published: 2006