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Journal Articles

MLL ( KMT2A)- rearranged Acute Lymphoblastic Leukemias Are Addicted to S-Adenosyl Methionine (SAM): Implications for Therapy

Trisha Tee, Titine Ruiter, Danique Wajon, Shuiyan Wu, Ahmed Dahaoui, Dorette S van Ingen Schenau, Laurens T van der Meer, Frank N van Leeuwen

Blood (2022) 140 (Supplement 1): 6343–6344.

https://doi.org/10.1182/blood-2022-159450

Published: 2022

Journal Articles

Mutational Mechanisms in Pediatric Acute Lymphoblastic Leukemia with Multiple Relapses

Cédric G van der Ham, Stefan H Lelieveld, Željko Antic, Marley Yeong, Lianne C Suurenbroek, Dorette S van Ingen Schenau, Lennart A. Kester, Liset Westera, Edwin Sonneveld, Peter M. Hoogerbrugge, Vincent H.J. van der Velden, Frank N van Leeuwen, Roland P. Kuiper

Blood (2022) 140 (Supplement 1): 3463–3464.

https://doi.org/10.1182/blood-2022-159410

Published: 2022

Journal Articles

Histone Deacetylase Inhibition Restores Therapy Response in TP53 mutated Acute Lymphoblastic Leukemia to Chemotherapy

Willem Cox, Miriam Butler, Dorette S van Ingen Schenau, Nadia Anderson, Lieke de Groot, Laurens T van der Meer, Frank N van Leeuwen

Blood (2022) 140 (Supplement 1): 3132–3133.

https://doi.org/10.1182/blood-2022-157118

Published: 2022

Journal Articles

BTK inhibition sensitizes acute lymphoblastic leukemia to asparaginase by suppressing the amino acid response pathway

Miriam Butler, Dorette S. van Ingen Schenau, Jiangyan Yu, Silvia Jenni, Maria P. Dobay, Rico Hagelaar, Britt M. T. Vervoort, Trisha M. Tee, Fieke W. Hoff, Jules P. Meijerink, Steven M. Kornblau, Beat Bornhauser, Jean-Pierre Bourquin, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen

Blood (2021) 138 (23): 2383–2395.

https://doi.org/10.1182/blood.2021011787

Published: 2021

Includes: Supplemental data