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Journal Articles

Neutrophils Regulate Bone Formation Via IL-1b Secretion

Kanako Wakahashi, Jiangyan Yu, Andrea Rubio-Ponce, Stephan Culeman, Brenda Krishacoumar, Carina Scholtysek, Gerhard Krönke, Andreas Schlitzer, Andrés Hidalgo
Journal: Blood
Blood (2022) 140 (Supplement 1): 1261–1262.
https://doi.org/10.1182/blood-2022-167733
Published: 2022
Journal Articles

BTK inhibition sensitizes acute lymphoblastic leukemia to asparaginase by suppressing the amino acid response pathway

Miriam Butler, Dorette S. van Ingen Schenau, Jiangyan Yu, Silvia Jenni, Maria P. Dobay, Rico Hagelaar, Britt M. T. Vervoort, Trisha M. Tee, Fieke W. Hoff, Jules P. Meijerink, Steven M. Kornblau, Beat Bornhauser, Jean-Pierre Bourquin, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen
Journal: Blood
Blood (2021) 138 (23): 2383–2395.
https://doi.org/10.1182/blood.2021011787
Published: 2021
Includes: Supplemental data
Journal Articles

A CRISPR/Cas9 Based Kinome Screen Identifies Bruton Tyrosine Kinase (BTK) As an Important Determinant of Asparaginase Treatment Response in Acute Lymphoblastic Leukemia

Miriam Butler, MSc, Laurens Van Der Meer, PhD, Jiangyan Yu, Silvia Jenni, PhD, Maria Pamela Dobay, PhD, Peter Hoogerbrugge, MD, Beat Bornhauser, PhD, Jean-Pierre Bourquin, MD PhD, Roland P. Kuiper, PhD, Frank van Leeuwen, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 34.
https://doi.org/10.1182/blood.V130.Suppl_1.34.34
Published: 2017
Journal Articles

Genomic Architecture and Clonal Dynamics of Early Relapsed BCP-ALL

Zeljko Antic, MD, Jiangyan Yu, MSc, Simon V. van Reijmersdal, Renske Kuiper, Edwin Sonneveld, PhD, Frank N. van Leeuwen, PhD, Peter M. Hoogerbrugge, MD PhD, Esmé Waanders, PhD, Roland P. Kuiper, PhD
Journal: Blood
Blood (2016) 128 (22): 4072.
https://doi.org/10.1182/blood.V128.22.4072.4072
Published: 2016
Journal Articles

Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukemia

CME Clinical Trials & Observations
Julie A. E. Irving, Amir Enshaei, Catriona A. Parker, Rosemary Sutton, Roland P. Kuiper, Amy Erhorn, Lynne Minto, Nicola C. Venn, Tamara Law, Jiangyan Yu, Claire Schwab, Rosanna Davies, Elizabeth Matheson, Alysia Davies, Edwin Sonneveld, Monique L. den Boer, Sharon B. Love, Christine J. Harrison, Peter M. Hoogerbrugge, Tamas Revesz, Vaskar Saha, Anthony V. Moorman
Journal: Blood
Blood (2016) 128 (7): 911–922.
https://doi.org/10.1182/blood-2016-03-704973
Published: 2016
Includes: Supplemental data
Journal Articles

Crispr/Cas9 Based Kinome Screen Identifies Novel Targets That Determine Sensitivity for Asparaginase Therapy in Acute Lymphoblastic Leukemia

Laurens T Van Der Meer, PhD, Jiangyan Yu, MSc, Miriam Butler, MSc, Jolien M R van der Meer, MSc, Roland P Kuiper, PhD, Frank N van Leeuwen, PhD
Journal: Blood
Blood (2015) 126 (23): 2629.
https://doi.org/10.1182/blood.V126.23.2629.2629
Published: 2015
Journal Articles

Genetic Architecture of Relapsed Pediatric B Cell Precursor Acute Lymphoblastic Leukemia Are Related to the Intensity of Upfront Therapy

Jiangyan Yu, MSc, Esmé Waanders, PhD, Simon V. van Reijmersdal, Edwin Sonneveld, PhD, Frank N. van Leeuwen, PhD, Rob Pieters, MD PhD, Ad Geurts van Kessel, PhD, Peter M. Hoogerbrugge, MD PhD, Roland P. Kuiper, PhD
Journal: Blood
Blood (2015) 126 (23): 247.
https://doi.org/10.1182/blood.V126.23.247.247
Published: 2015
Journal Articles

Accurate Detection of Low Mosaic Mutations Associated with Therapy Resistance in Pediatric Acute Lymphoblastic Leukemia Using Single Molecule Tagging and Deep-Sequencing

Jiangyan Yu, MSc, Simon V. van Reijmersdal, Alexander Hoischen, PhD, Edwin Sonneveld, PhD, Peter M. Hoogerbrugge, MD PhD, Esmé Waanders, PhD, Roland P. Kuiper, PhD
Journal: Blood
Blood (2015) 126 (23): 2608.
https://doi.org/10.1182/blood.V126.23.2608.2608
Published: 2015
Journal Articles

Targeted Locus Amplification & Next Generation Sequencing for the Detection of Recurrent and Novel Gene Fusions for Improved Treatment Decisions in Pediatric Acute Lymphoblastic Leukemia

Roland P. Kuiper, PhD, Simon V. van Reijmersdal, Marieke Simonis, PhD, Jiangyan Yu, MSc, Edwin Sonneveld, PhD, Blanca Scheijen, PhD, Judith M. Boer, PhD, Aurélie Boeree, BSc, Petra Klous, MSc, Peter M Hoogerbrugge, MD PhD, Mehmet Yilmaz, MSc, Frank N. van Leeuwen, PhD, Monique L. Den Boer, PhD, Erik Splinter, PhD
Journal: Blood
Blood (2015) 126 (23): 696.
https://doi.org/10.1182/blood.V126.23.696.696
Published: 2015
Journal Articles

The Majority of RAS Pathway Mutations Detected in Relapsed B-Cell Precursor Acute Lymphoblastic Leukemia Are Present in Major or Minor Subclones at Diagnosis

Jiangyan Yu, Esmé Waanders, PhD, Simon V. van Reijmersdal, Edwin Sonneveld, PhD, Peter M Hoogerbrugge, MD PhD, Frank N. van Leeuwen, PhD, Ad Geurts van Kessel, PhD, Roland P. Kuiper, PhD
Journal: Blood
Blood (2014) 124 (21): 2397.
https://doi.org/10.1182/blood.V124.21.2397.2397
Published: 2014