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Emily McIntyre
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Journal Articles

Cytoplasmic Nucleophosmin (NPMc+) Mutations and FMS-Like Tyrosine Kinase 3 (Flt3) Internal Tandem Duplication (ITD) Mutations Cooperate to Cause Leukemia In a Mouse Model

Rachel E. Rau, MD, Daniel Magoon, Emily McIntyre, Li Li, PhD, Sarah Greenblatt, David Huso, DVM, PhD, Pier Paolo Pandolfi, MD, PhD, Donald Small, MD, PhD, Patrick Brown, MD
Journal: Blood
Blood (2010) 116 (21): 145.
https://doi.org/10.1182/blood.V116.21.145.145
Published: 2010
Journal Articles

Upregulation of Surface CXCR4 In Response to Chemotherapy Confers a Stromal-Mediated Survival Advantage In Acute Leukemia

Edward Allan R. Sison, MD, Emily McIntyre, Daniel Magoon, Patrick Brown, MD
Journal: Blood
Blood (2010) 116 (21): 2734.
https://doi.org/10.1182/blood.V116.21.2734.2734
Published: 2010
Journal Articles

Promoter hypermethylation in MLL -r infant acute lymphoblastic leukemia: biology and therapeutic targeting

Eric Schafer, Rafael Irizarry, Sandeep Negi, Emily McIntyre, Donald Small, Maria E. Figueroa, Ari Melnick, Patrick Brown
Journal: Blood
Blood (2010) 115 (23): 4798–4809.
https://doi.org/10.1182/blood-2009-09-243634
Published: 2010
Includes: Supplemental data
Journal Articles

Combinations of the Histone Deacetylase Inhibitor Entinostat (SNDX-275, MS-275) and Imatinib Have Divergent Effects in Imatinib-Sensitive Vs. Imatinib-Resistant p210- BCR/ABL Expressing Cell Lines.

Rachel E. Rau, MD, Emily McIntyre, Scott H. Kaufmann, MD, PhD, Igor Espinoza-Delgado, MD, Judith Karp, Patrick Brown, MD
Journal: Blood
Blood (2009) 114 (22): 2742.
https://doi.org/10.1182/blood.V114.22.2742.2742
Published: 2009
Journal Articles

Promoter Hypermethylation in MLL-r Leukemia: Biology and Therapeutic Targeting.

Eric S. Schafer, MD, Rafael Irizarry, Sandeep Negi, PhD, Emily McIntyre, Donald Small, MD, PhD, Maria E Figueroa, MD, Ari Melnick, Patrick Brown, MD
Journal: Blood
Blood (2009) 114 (22): 3472.
https://doi.org/10.1182/blood.V114.22.3472.3472
Published: 2009
Journal Articles

Discordance of MLL-rearranged (MLL-R) infant acute lymphoblastic leukemia in monozygotic twins with spontaneous clearance of preleukemic clone in unaffected twin

Brief Report
Meredith K. Chuk, Emily McIntyre, Donald Small, Patrick Brown
Journal: Blood
Blood (2009) 113 (26): 6691–6694.
https://doi.org/10.1182/blood-2009-01-202259
Published: 2009
Journal Articles

Disruption of Leukemia Stem Cell (LSC) Interactions with Bone Marrow Stromal Niche Enhances Efficacy of FLT3 Tyrosine Kinase Inhibitors (TKI) in Vivo

Patrick Brown, MD, Emily McIntyre, Li Li, PhD, Donald Small, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 383.
https://doi.org/10.1182/blood.V112.11.383.383
Published: 2008
Journal Articles

High Level Expression of Wild Type FLT3 Is Associated with Poor Outcome and Selective Sensitivity to FLT3 Inhibitors in Childhood Acute Myeloid Leukemia: A Children’s Oncology Group Study

Patrick Brown, MD, Todd Alonzo, PhD, Robert Gerbing, Emily McIntyre, Beverly Lange, MD, Donald Small, Soheil Meshinchi, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 147.
https://doi.org/10.1182/blood.V112.11.147.147
Published: 2008
Journal Articles

Discordance of MLL-Rearranged (MLL-R) Infant ALL in Monozygotic Twins with Spontaneous Clearance of Preleukemic Clone in Unaffected Twin

Meredith Chuk, MD, Emily McIntyre, Donald Small, MD, PhD, Patrick Brown, MD
Journal: Blood
Blood (2008) 112 (11): 2543.
https://doi.org/10.1182/blood.V112.11.2543.2543
Published: 2008
Journal Articles

The incidence and clinical significance of nucleophosmin mutations in childhood AML

Patrick Brown, Emily McIntyre, Rachel Rau, Soheil Meshinchi, Norman Lacayo, Gary Dahl, Todd A. Alonzo, Myron Chang, Robert J. Arceci, Donald Small
Journal: Blood
Blood (2007) 110 (3): 979–985.
https://doi.org/10.1182/blood-2007-02-076604
Published: 2007
Journal Articles

Incidence and Clinical Significance of Nucleophosmin Mutations in Childhood AML: A Childrens Oncology Group Study.

Patrick Brown, MD, Emily McIntyre, Rachel Rau, MD, Todd A. Alonzo, PhD, Robert Gerbing, MA, Soheil Meshinchi, MD PhD, Norman Lacayo, MD, Myron Chang, PhD, Robert Arceci, MD PhD, Donald Small, MD PhD
Journal: Blood
Blood (2006) 108 (11): 221.
https://doi.org/10.1182/blood.V108.11.221.221
Published: 2006
Journal Articles

Combinations of the FLT3 Inhibitor CEP-701 and Chemotherapy Synergistically Kill Infant and Childhood MLL-Rearranged ALL Cells in a Sequence-Dependent Manner.

Patrick Brown, MD, Mark Levis, MD, PhD, Emily McIntyre, Melissa Griesemer, Donald Small, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2467.
https://doi.org/10.1182/blood.V106.11.2467.2467
Published: 2005