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Journal Articles

Comprehensive Sequence Analysis of Relapse and Refractory Pediatric Acute Myeloid Leukemia Identifies miRNA and mRNA Transcripts Associated with Treatment Resistance - a Report from the COG/NCI-Target AML Initiative

Emilia L. Lim, Diane L. Trinh, MSc, Rhonda E. Ries, MA, Yussanne Ma, PhD, James Topham, Maya D. Hughes, MD, Erin Pleasance, PhD, Andrew J. Mungall, PhD, Richard Moore, PhD, Yongjun Zhao, PhD, Daniela S. Gerhard, PhD, Vivian Oehler, MD, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Malcolm A. Smith, MD PhD, Todd A. Alonzo, PhD, Robert J. Arceci, MD PhD, Soheil Meshinchi, MD PhD, Marco A. Marra, PhD

Blood (2015) 126 (23): 687.

https://doi.org/10.1182/blood.V126.23.687.687

Published: 2015

Journal Articles

Evaluation Of Afuresertib, An Oral Pan-AKT Inhibitor, In Patients With Langerhans Cell Histiocytosis

Robert J. Arceci, M.D., Ph.D., Carl E. Allen, MD, PhD, Ira Dunkel, M.D., Eric D. Jacobsen, MD, James Whitlock, Robert Vassallo, M.D., Ivan M. Borrello, MD, Allen Oliff, MD, Shannon R. Morris, MD, PhD, Beth Ann M Reedy, Alison Portnoy, Deborah A. Smith, PharmD, Bob Noble, Amy A. Murnane, Stephen A. Szabo, Carlos Rodriguez-Galindo, Mark L. Heaney, MD, PhD, Kenneth L. McClain, MD, PhD, Sarah Vaseilbuh, MD

Blood (2013) 122 (21): 2907.

https://doi.org/10.1182/blood.V122.21.2907.2907

Published: 2013

Journal Articles

Coordinate Changes In RNA Expression, Transcript Splicing, and DNA Methylation In Pediatric AML

Jason Farrar, M.D., Michael Ochs, Ph.D., David W Lee, C.C. Talbot, Jr., Jonathan Buckley, M.D., Ph.D., Soheil Meshinchi, MD, PhD, Robert J Arceci, M.D., Ph.D.

Blood (2013) 122 (21): 3761.

https://doi.org/10.1182/blood.V122.21.3761.3761

Published: 2013

Journal Articles

PIM3-SCO2 Fusion Is a Novel Transcription-Induced Chimera That Is Highly Prevalent In Childhood AML

Julia Kuhn, BA, Daoud Meerzaman, MD, Rhonda E. Ries, MA, Filippo Milano, MD, PhD, Alan S. Gamis, MD, MPH, Todd A. Alonzo, PhD, Jaime Guidry-Auvil, Ph.D., Tanja M. Davidsen, PhD, Malcolm A. Smith, MD, PhD, Yan Chunhua, Chih Hao Hsu, Cu Nguyen, Daniela S. Gerhard, Ph.D., Daniel Wai, Robert J. Arceci, MD, PhD, Soheil Meshinchi, MD, PhD

Blood (2013) 122 (21): 2549.

https://doi.org/10.1182/blood.V122.21.2549.2549

Published: 2013

Journal Articles

Autosomal Recessive Diamond-Blackfan Anemia: Identification Of Mutations In MCM2 and Flnb

Kelly A O'Brien, PhD, Nancy E Seidel, Jason Farrar, M.D., Adrianna Vlachos, MD, Nisc Comparative Sequencing Program, Stacie M Anderson, Xiuli An, MD, PhD, Eva Atsidaftos, MS, Harry Malech, MD, Robert J Arceci, M.D., Ph.D., Steven R Ellis, PhD, Jeffrey M. Lipton, MD, PhD, David M. Bodine, PhD

Blood (2013) 122 (21): 589.

https://doi.org/10.1182/blood.V122.21.589.589

Published: 2013

Journal Articles

Diminutive somatic deletions in the 5q region lead to a phenotype atypical of classical 5q− syndrome

Adrianna Vlachos, Jason E. Farrar, Eva Atsidaftos, Ellen Muir, Anupama Narla, Thomas C. Markello, Sharon A. Singh, Michael Landowski, Hanna T. Gazda, Lionel Blanc, Johnson M. Liu, Steven R. Ellis, Robert J. Arceci, Benjamin L. Ebert, David M. Bodine, Jeffrey M. Lipton

Blood (2013) 122 (14): 2487–2490.

https://doi.org/10.1182/blood-2013-06-509935

Published: 2013

Journal Articles

When “rare” is no excuse for progress

Donna Neuberg, Robert J. Arceci

Blood (2013) 121 (25): 4970–4972.

https://doi.org/10.1182/blood-2013-05-498675

Published: 2013

Journal Articles

Interim Report of a Randomized, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of Decitabine As an Epigenetic Priming Agent When Combined with Induction Chemotherapy in Pediatric Patients (pts) with Newly Diagnosed Acute Myelogenous Leukemia (AML)

Lia Gore, MD, Margaret E. Macy, M.D., Francoise Mechinaud, MD, Aru Narendran, MD, PhD, Frank Alvaro, MD, Carola A.S. Arndt, MD, Phillip Barnette, MD, Jessica Boklan, MD, Todd Cooper, DO, Laura Martin, MD, W Tcheng, MD, Peter Tarassoff, MD, Mark M Jones, MD, Soheil Meshinchi, MD, PhD, Robert J. Arceci, MD, PhD

Blood (2012) 120 (21): 1517.

https://doi.org/10.1182/blood.V120.21.1517.1517

Published: 2012

Journal Articles

Clinically Significant Mutations, Deletions and Translocations Involving ETV6 Identified by Whole Genome and Whole Exome Sequencing; Report From NCI/COG Target AML Initiative

Heather L. Helton, MD, Rhonda E. Ries, MA, Todd A. Alonzo, PhD, Robert B. Gerbing, M.A., Lisa R. Trevino, PhD, Jason Farrar, M.D., Jaime M. Guidry Auvil, Ph.D., Tanja M. Davidsen, PhD, Patee Gesuwan, Ph.D., Donna M. Muzny, Alan S. Gamis, MD, MPH, Janet Franklin, MD, MPH, David A. Wheeler, PhD, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Robert J. Arceci, MD, PhD, Soheil Meshinchi, MD, PhD

Blood (2012) 120 (21): 125.

https://doi.org/10.1182/blood.V120.21.125.125

Published: 2012

Journal Articles

Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution From Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – an NCI/COG Target AML Study

Soheil Meshinchi, MD, PhD, Rhonda E. Ries, MA, Lisa R. Trevino, PhD, Oliver A. Hampton, PhD, Todd Alonzo, PhD, Jason E. Farrar, MD, Jaime M. Guidry Auvil, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, PhD, Donna M. Muzny, Alan S. Gamis, MD, MPH, Heather L. Helton, MD, David A. Wheeler, PhD, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Robert J. Arceci, MD, PhD

Blood (2012) 120 (21): 123.

https://doi.org/10.1182/blood.V120.21.123.123

Published: 2012

Journal Articles

Genome Wide Promoter Methylation Patterns Predict AML Subtype Outcomes and Identify Novel Pathways Characterizing Diagnostic and Relapsed Disease in Children

Michael Ochs, Ph.D., Jason Farrar, M.D., Michael Considine, M.S., Rhonda E. Ries, MA, Lisa R. Trevino, PhD, Todd A. Alonzo, PhD, Jaime Guidry-Auvil, Ph.D., Tanja M. Davidsen, PhD, Patee Gesuwan, Ph.D., Donna M. Muzny, Alan S. Gamis, MD, MPH, David A. Wheeler, PhD, Heather L. Helton, MD, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Soheil Meshinchi, MD, PhD, Robert J. Arceci, MD, PhD

Blood (2012) 120 (21): 1287.

https://doi.org/10.1182/blood.V120.21.1287.1287

Published: 2012

Journal Articles

Insights Into Diagnosis and Etiology of Diamond Blackfan Anemia by Analysis of Pre-rRNA Processing

Ross Fisher, MD, Adrianna Henson, Paola Quarello, MD, Anna Aspesi, PhD, Jason E Farrar, MD, Robert J. Arceci, MD, PhD, David M. Bodine, PhD, Irma Dianzani, MD PhD, Jeffrey M. Lipton, MD, PhD, Ugo Ramenghi, MD, Adrianna Vlachos, MD, Steven R Ellis, PhD

Blood (2012) 120 (21): 3476.

https://doi.org/10.1182/blood.V120.21.3476.3476

Published: 2012

Journal Articles

Integrative Network Analysis of Pediatric AML Whole Genomes, cDNA Expression and Clinical Data Elements Reveals Shared As Well As t(8;21), Inv16 and MLL Specific Pathways; A Report From COG/NCI Target AML Initiative

Hamid Bolouri, PhD, Rhonda E. Ries, MA, Ranjani Ramamurthy, MS, Todd A. Alonzo, PhD, Jaime M. Guidry Auvil, Ph.D., Tanja M. Davidsen, PhD, Patee Gesuwan, Ph.D., Alan S. Gamis, MD, MPH, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Robert J. Arceci, MD, PhD, Soheil Meshinchi, MD, PhD

Blood (2012) 120 (21): 3519.

https://doi.org/10.1182/blood.V120.21.3519.3519

Published: 2012

Journal Articles

Ribosomal protein gene deletions in Diamond-Blackfan anemia

Jason E. Farrar, Adrianna Vlachos, Eva Atsidaftos, Hannah Carlson-Donohoe, Thomas C. Markello, Robert J. Arceci, Steven R. Ellis, Jeffrey M. Lipton, David M. Bodine

Blood (2011) 118 (26): 6943–6951.

https://doi.org/10.1182/blood-2011-08-375170

Published: 2011

Journal Articles

Natural history of transient myeloproliferative disorder clinically diagnosed in Down syndrome neonates: a report from the Children's Oncology Group Study A2971

Alan S. Gamis, Todd A. Alonzo, Robert B. Gerbing, Joanne M. Hilden, April D. Sorrell, Mukta Sharma, Thomas W. Loew, Robert J. Arceci, Dorothy Barnard, John Doyle, Gita Massey, John Perentesis, Yaddanapudi Ravindranath, Jeffrey Taub, Franklin O. Smith

Blood (2011) 118 (26): 6752–6759.

https://doi.org/10.1182/blood-2011-04-350017

Published: 2011

Includes: Supplemental data

Journal Articles

SNP Array Genotyping Reveals Constitutional and Mosaic Losses of Ribosomal Protein Gene Regions In Patients with Diamond Blackfan Anemia without Ribosomal Protein Gene Mutations.

Jason E. Farrar, MD, Adrianna Vlachos, MD, Eva Atsidaftos, MS, Hannah Carlson-Donohoe, Steven R. Ellis, PhD, Thomas C. Markello, MD, PhD, Robert J. Arceci, MD, PhD, Jeffrey M. Lipton, MD, PhD, David M. Bodine, PhD

Blood (2010) 116 (21): 1168.

https://doi.org/10.1182/blood.V116.21.1168.1168

Published: 2010

Journal Articles

5q- Myelodysplastic Syndrome, In One of 23 Children Lacking a Known Ribosomal Gene Mutation, Masquerading as Diamond Blackfan Anemia (DBA) and Responding to Lenalidomide

Adrianna Vlachos, MD, Jason Farrar, MD, Eva Atsidaftos, MS, Ellen Muir, RN, CNS, Thomas C. Markello, MD, PhD, Sharon Singh, MD, Johnson M. Liu, MD, Steven Ellis, PhD, Robert J. Arceci, MD, PhD, David M. Bodine, PhD, Jeffrey Michael Lipton, MD, PhD

Blood (2010) 116 (21): LBA-2.

https://doi.org/10.1182/blood.V116.21.LBA-2.LBA-2

Published: 2010

Journal Articles

Single Cell Network Profiling (SCNP) Signatures Predict Response to Induction Therapy and Relapse Risk In Pediatric Patients with Acute Myeloid Leukemia: Children's Oncology Group (COG) Study POG-9421

Norman J. Lacayo, MD, Aileen Cohen, Ph.D., M.D., Matt Westfall, Ph.D., Alan Lackey, MS, Xiaohua (Robert) Xin, Ph.D., M.D., Urte Gayko, Ph.D., Santosh Putta, Ph.D., Soheil Meshinchi, MD, PhD, Susana C. Raimondi, PhD, Todd A. Alonzo, PhD, Robert J. Arceci, MD, PhD, Yaddanapudi Ravindranath, MD, Gary Van Houten Dahl, MD, Alessandra Cesano, MD

Blood (2010) 116 (21): 954.

https://doi.org/10.1182/blood.V116.21.954.954

Published: 2010

Journal Articles

5q- Syndrome In a Child: Is This Acquired Diamond Blackfan Anemia (DBA)?

Adrianna Vlachos, MD, Jason Farrar, MD, Eva Atsidaftos, MS, Ellen Muir, MSN, CNS, Thomas C. Markello, MD, PhD, Sharon Singh, MD, Johnson M. Liu, MD, Steven Ellis, PhD, Robert J. Arceci, MD, PhD, David M. Bodine, PhD, Jeffrey Michael Lipton, MD, PhD

Blood (2010) 116 (21): 4430.

https://doi.org/10.1182/blood.V116.21.4430.4430

Published: 2010

Journal Articles

BRAF, a piece of the LCH puzzle

Kim E. Nichols, Robert J. Arceci

Blood (2010) 116 (11): 1825–1827.

https://doi.org/10.1182/blood-2010-06-289934

Published: 2010

NARROW

Comprehensive Sequence Analysis of Relapse and Refractory Pediatric Acute Myeloid Leukemia Identifies miRNA and mRNA Transcripts Associated with Treatment Resistance - a Report from the COG/NCI-Target AML Initiative

Evaluation Of Afuresertib, An Oral Pan-AKT Inhibitor, In Patients With Langerhans Cell Histiocytosis

Coordinate Changes In RNA Expression, Transcript Splicing, and DNA Methylation In Pediatric AML

PIM3-SCO2 Fusion Is a Novel Transcription-Induced Chimera That Is Highly Prevalent In Childhood AML

Autosomal Recessive Diamond-Blackfan Anemia: Identification Of Mutations In MCM2 and Flnb

Diminutive somatic deletions in the 5q region lead to a phenotype atypical of classical 5q− syndrome

When “rare” is no excuse for progress

Interim Report of a Randomized, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of Decitabine As an Epigenetic Priming Agent When Combined with Induction Chemotherapy in Pediatric Patients (pts) with Newly Diagnosed Acute Myelogenous Leukemia (AML)

Clinically Significant Mutations, Deletions and Translocations Involving ETV6 Identified by Whole Genome and Whole Exome Sequencing; Report From NCI/COG Target AML Initiative

Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution From Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – an NCI/COG Target AML Study

Genome Wide Promoter Methylation Patterns Predict AML Subtype Outcomes and Identify Novel Pathways Characterizing Diagnostic and Relapsed Disease in Children

Insights Into Diagnosis and Etiology of Diamond Blackfan Anemia by Analysis of Pre-rRNA Processing

Integrative Network Analysis of Pediatric AML Whole Genomes, cDNA Expression and Clinical Data Elements Reveals Shared As Well As t(8;21), Inv16 and MLL Specific Pathways; A Report From COG/NCI Target AML Initiative

Ribosomal protein gene deletions in Diamond-Blackfan anemia

Natural history of transient myeloproliferative disorder clinically diagnosed in Down syndrome neonates: a report from the Children's Oncology Group Study A2971

SNP Array Genotyping Reveals Constitutional and Mosaic Losses of Ribosomal Protein Gene Regions In Patients with Diamond Blackfan Anemia without Ribosomal Protein Gene Mutations.

5q- Myelodysplastic Syndrome, In One of 23 Children Lacking a Known Ribosomal Gene Mutation, Masquerading as Diamond Blackfan Anemia (DBA) and Responding to Lenalidomide

Single Cell Network Profiling (SCNP) Signatures Predict Response to Induction Therapy and Relapse Risk In Pediatric Patients with Acute Myeloid Leukemia: Children's Oncology Group (COG) Study POG-9421

5q- Syndrome In a Child: Is This Acquired Diamond Blackfan Anemia (DBA)?

BRAF, a piece of the LCH puzzle

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