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Journal Articles

Integrated Methylation and Transcriptional Landscape and Evolution of Pediatric AML

Benjamin J Huang, Hamid Bolouri, Colin Y. Smith, Jim Wang, Rhonda E Ries, Elizabeth Conran, Alan S Gamis, Richard Aplenc, Todd A. Alonzo, Xiaotu Ma, Timothy Junius Triche, Jason E Farrar, Soheil Meshinchi

Blood (2023) 142 (Supplement 1): 2956.

https://doi.org/10.1182/blood-2023-187819

Published: 2023

Journal Articles

Lymphoid Malignancies in Shwachman-Diamond Syndrome: Incidence, Clinical Features, and Outcomes from the North American SDS Registry

Helen D Reed, Hyunwoo Do, Edie Weller, Jason E Farrar, Christopher Gamper, Bonnie W Lau, Lauren Pommert, Ian Atkinson, Margret Joos, Sara Loveless, Sarah Steltz, Kasiani Myers, Akiko Shimamura

Blood (2023) 142 (Supplement 1): 5662.

https://doi.org/10.1182/blood-2023-174256

Published: 2023

Journal Articles

Eltrombopag in Pediatric Patients with Previously Untreated or Refractory/Relapsed Severe Aplastic Anemia: The Phase II Escalate Trial

Akiko Shimamura, Alexey Maschan, Carolyn Bennett, Jason E Farrar, Sujith Samarasinghe, Brigitte Strahm, Winfred C. Wang, Adrianna Vlachos, Charlotte M. Niemeyer, Timothy S. Olson, Denise D'Alessio, Elise Burmeister Getz, Tomasz Lawniczek, Yunnan Xu, David A. Williams

Blood (2022) 140 (Supplement 1): 705–707.

https://doi.org/10.1182/blood-2022-158214

Published: 2022

Journal Articles

Expanding the High-Risk Definition for Children with Newly Diagnosed Acute Myeloid Leukemia

Adam J. Lamble, Rhonda E. Ries, Todd A. Alonzo, Yi-Cheng Wang, Jason E Farrar, Benjamin J. Huang, Matthew A. Kutny, Jessica A. Pollard, Richard Aplenc, Alan S. Gamis, Edward A. Kolb, Todd M. Cooper, Soheil Meshinchi

Blood (2022) 140 (Supplement 1): 3393–3394.

https://doi.org/10.1182/blood-2022-167680

Published: 2022

Journal Articles

Transcriptome Analysis and Machine Learning Prioritize Therapeutic Strategies for High-Risk Pediatric AML Patients of the KMT2A-Fusion Subgroup

Alyssa Obermayer, Sijie Yao, Jenny L. Smith, Rhonda E. Ries, Yi-Cheng Wang, Jason E Farrar, Scott N Furlan, Tim Triche, Xiaotu Ma, Benjamin J. Huang, Xuefeng Wang, Soheil Meshinchi, Timothy I. Shaw

Blood (2022) 140 (Supplement 1): 3385–3386.

https://doi.org/10.1182/blood-2022-163616

Published: 2022

Journal Articles

A Robust Long Non-Coding RNA Expression Classifier for Risk Stratification in Pediatric AML

Jason E Farrar, Jenny L. Smith, Megan Othus, Benjamin J. Huang, Yi-Cheng Wang, Rhonda E. Ries, Tiffany A. Hylkema, Era L Pogosova-Agadjanyan, Sneha Challa, Amanda R. Leonti, Timothy I. Shaw, Timothy Junius Triche, Jr., Alan S. Gamis, Richard Aplenc, Anders E. Kolb, Xiaotu Ma, Derek Stirewalt, Todd A. Alonzo, Soheil Meshinchi

Blood (2022) 140 (Supplement 1): 9173–9174.

https://doi.org/10.1182/blood-2022-168296

Published: 2022

Journal Articles

Integrated Transcriptomics and Proteomics Identifies Therapeutic Targets in Pediatric Acute Myeloid Leukemia

Benjamin J. Huang, Jenny L. Smith, Timothy I. Shaw, Scott N Furlan, Rhonda E. Ries, Amanda R. Leonti, Erin Lynn Crowgey, Lisa Wei, Jason E Farrar, Tim Triche, Xiaotu Ma, Quy Le, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 1296.

https://doi.org/10.1182/blood-2021-153970

Published: 2021

Journal Articles

Liposome-Encapsulated Cytarabine and Daunorubicin (CPX-351) Induces Remission in Newly Diagnosed Pediatric Secondary Myeloid Malignancies

Kenneth J Caldwell, Yixin Hu, Mihaela Onciu, Sara M Federico, Marta Salek, Sara Lewis, Shaohua Lei, Jinghui Zhang, Kim E. Nichols, Clifford M Takemoto, Brandon M Triplett, Jason E Farrar, Jeffrey E. Rubnitz, Raul C Ribeiro, Marcin W. Wlodarski

Blood (2021) 138 (Supplement 1): 4415.

https://doi.org/10.1182/blood-2021-149619

Published: 2021

Journal Articles

Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors

Samrat Roy Choudhury, Jordan T Bird, Stephanie Byrum, Dane Jester, Troy Davidson, Giselle Almeida Gonzalez, David Becton, Jenny L. Smith, Rhonda E. Ries, Soheil Meshinchi, Jason E Farrar

Blood (2021) 138 (Supplement 1): 2208.

https://doi.org/10.1182/blood-2021-148574

Published: 2021

Journal Articles

Epigenetic Silencing of CD34 in AML and Association with Outcome in KMT2A Fusions

Rhonda E. Ries, Lisa Eidenschink Brodersen, Laura Pardo, Timothy Junius Triche, Jr., Amanda R. Leonti, Jenny L. Smith, Todd A. Alonzo, Jason E Farrar, Yi-Cheng Wang, Alice Dang, Alan S. Gamis, Richard Aplenc, E. Anders Kolb, Michael R. Loken, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 802.

https://doi.org/10.1182/blood-2021-149210

Published: 2021

Journal Articles

Whole Genome Sequencing of Diamond Blackfan Anemia Syndrome Patients Detects Mutations That Alter mRNA Splicing

Stanley R Clarke, Adrianna Vlachos, Jens Lichtenberg, Nancy E Seidel, Jaya Jagadeesh, NISC Comparative SequencingProgram, Adam M. Phillippy, Jason E Farrar, Steven R Ellis, Irma Dianzani, Jeffrey M Lipton, David M Bodine

Blood (2021) 138 (Supplement 1): 863.

https://doi.org/10.1182/blood-2021-145622

Published: 2021

Journal Articles

EZH2-Mediated MHC Class II Silencing Drives Immune Evasion in AML with t(16;21) ( FUS-ERG)

Nate J Buteyn, Connor G Burke, Jenny L. Smith, Rhonda E. Ries, Amanda R. Leonti, Timothy I. Shaw, Benjamin J. Huang, Todd A. Alonzo, Scott N. Furlan, Jason E Farrar, Soheil Meshinchi, Timothy Junius Triche, Jr.

Blood (2021) 138 (Supplement 1): 374.

https://doi.org/10.1182/blood-2021-153256

Published: 2021

Journal Articles

Integrated Stem Cell Signature and Cytomolecular Risk Determination in Pediatric Acute Myeloid Leukemia

Benjamin J. Huang, MD, Jenny L. Smith, MSc, MD, Rhonda E. Ries, MA, Amanda R. Leonti, MS, Erin Lynn Crowgey, PhD, Scott N. Furlan, MD, Timothy Shaw, PhD, Lisa Wei, BS, Yi-Cheng Wang, MS, Robert B. Gerbing, MA, Todd A. Alonzo, PhD, Todd M. Cooper, DO, Edward A. Kolb, MD, Xiaotu Ma, PhD, Jason E. Farrar, MD, Timothy Junius Triche, Jr., PhD, Soheil Meshinchi, MDPhD

Blood (2020) 136 (Supplement 1): 28–29.

https://doi.org/10.1182/blood-2020-142638

Published: 2020

Journal Articles

Genome and Transcriptome Profiling of Monosomy 7 AML Defines Novel Risk and Therapeutic Cohorts

Blood (2020) 136 (Supplement 1): 20–21.

https://doi.org/10.1182/blood-2020-137244

Published: 2020

Journal Articles

Discovery of Novel IL3RA (CD123) Isoforms By Long Read Transcriptomics, Heterogeneous Expression Among AML Patient Cohorts and the Implications for Anti-CD123 Therapeutics

Jason G Underwood, PhD BA, Jenny L. Smith, MSc, MD, Lindsey F. Call, B.A., Elizabeth Tseng, PhD, Tiffany A. Hylkema, BS, Rhonda E. Ries, MA, Amanda R. Leonti, MS, Jason E. Farrar, MD, Timothy Junius Triche, Jr., PhD, Soheil Meshinchi, MD PhD

Blood (2019) 134 (Supplement_1): 4658.

https://doi.org/10.1182/blood-2019-131508

Published: 2019

Journal Articles

Whole Genome Sequencing Identifies Small Deletions in Ribosomal Genes Causing Diamond Blackfan Anemia

David M. Bodine, PhD, Jens Lichtenberg, Nancy Seidel, NISC Comparative SequencingProgram, G. Jayashree Jagadeesh, John G Conboy, PhD, Jason E. Farrar, MD, Jessica Kang, BS, Lionel Blanc, PhD, Evangelia Atsidaftos, MA, MPH, Steven Ellis, PhD, Jeffrey Michael M Lipton, MD PhD, Adrianna Vlachos, MD

Blood (2019) 134 (Supplement_1): 2502.

https://doi.org/10.1182/blood-2019-121710

Published: 2019

Journal Articles

Structural Variants Involving MLLT10/AF10 Are Associated with Adverse Outcome in AML Regardless of the Partner Gene - a COG/Tpaml Study

Rhonda E. Ries, MA, Amanda R. Leonti, MS, Timothy Junius Triche, Jr., PhD, Robert B. Gerbing, Betsy A Hirsch, PhD, Susana C. Raimondi, PhD, Jenny L. Smith, MSc, MD, Todd M Cooper, DO, Jason E. Farrar, MD, Aniruddha J. Deshpande, E. Anders Kolb, MD, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Todd A. Alonzo, PhD, Soheil Meshinchi, MD PhD

Blood (2019) 134 (Supplement_1): 461.

https://doi.org/10.1182/blood-2019-125943

Published: 2019

Journal Articles

A Distinct Oncofetal B-Cell Transcriptional Program Is Activated in Infant Acute Myeloid Leukemia and Reveals Novel Therapeutic Strategies

Hamid Bolouri, PhD, Benjamin K. Johnson, PhD, Rhonda E. Ries, MA, Laura Pardo, Tiffany A. Hylkema, BS, Wanding Zhou, PhD, Jenny L. Smith, MSc, MD, Amanda R. Leonti, MS, Allison Kaeding, MD, Michael R. Loken, PhD, Jason E. Farrar, MD, Soheil Meshinchi, MD PhD, Timothy Junius Triche, Jr., PhD

Blood (2019) 134 (Supplement_1): 3768.

https://doi.org/10.1182/blood-2019-123487

Published: 2019

Journal Articles

Long Non-Coding RNAs (lncRNAs) Are Highly Associated with Disease Characteristics and Outcome in Pediatric Acute Myeloid Leukemia - a COG and Tpaml Study

Jenny L. Smith, MSc, MD, Rhonda E. Ries, MA, Jason E. Farrar, MD, Todd A. Alonzo, PhD, Robert B. Gerbing, Amanda R. Leonti, MS, Tiffany A. Hylkema, BS, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Edward Anders Kolb, MD, Cu Nguyen, Daoud Meerzaman, Timothy Junius Triche, Jr., PhD, Soheil Meshinchi, MD PhD

Blood (2019) 134 (Supplement_1): 2741.

https://doi.org/10.1182/blood-2019-127318

Published: 2019

Journal Articles

Phenotypes of Diamond Blackfan Anemia Patients with RPL35A Haploinsufficiency Due to 3q29 Deletion Compared with RPL35A Single Nucleotide Variants or Small Insertion/Deletions

Neelam Giri, MD, Matthew Gianferante, MD, Evangelia Atsidaftos, MA, MPH, Marcin W. Wlodarski, MD PhD, Paola Quarello, MD, Jana Volejnikova, MD, Polyxeni Delaporta, MD, Vijay G. Sankaran, MD PhD, Jason E. Farrar, MD, Maryam Hussain, MPH, Lisa J. McReynolds, MD PhD, Antonis Kattamis, Jeffrey M Lipton, MD PhD, Charlotte Niemeyer, MD, Dagmar Pospisilova, MD PhD, Ugo Ramenghi, MD, Sharon A. Savage, MD, Adrianna Vlachos, MD, Blanche P. Alter, MD MPH

Blood (2018) 132 (Supplement 1): 3854.

https://doi.org/10.1182/blood-2018-99-117171

Published: 2018

NARROW

Integrated Methylation and Transcriptional Landscape and Evolution of Pediatric AML

Lymphoid Malignancies in Shwachman-Diamond Syndrome: Incidence, Clinical Features, and Outcomes from the North American SDS Registry

Eltrombopag in Pediatric Patients with Previously Untreated or Refractory/Relapsed Severe Aplastic Anemia: The Phase II Escalate Trial

Expanding the High-Risk Definition for Children with Newly Diagnosed Acute Myeloid Leukemia

Transcriptome Analysis and Machine Learning Prioritize Therapeutic Strategies for High-Risk Pediatric AML Patients of the KMT2A-Fusion Subgroup

A Robust Long Non-Coding RNA Expression Classifier for Risk Stratification in Pediatric AML

Integrated Transcriptomics and Proteomics Identifies Therapeutic Targets in Pediatric Acute Myeloid Leukemia

Liposome-Encapsulated Cytarabine and Daunorubicin (CPX-351) Induces Remission in Newly Diagnosed Pediatric Secondary Myeloid Malignancies

Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors

Epigenetic Silencing of CD34 in AML and Association with Outcome in KMT2A Fusions

Whole Genome Sequencing of Diamond Blackfan Anemia Syndrome Patients Detects Mutations That Alter mRNA Splicing

EZH2-Mediated MHC Class II Silencing Drives Immune Evasion in AML with t(16;21) ( FUS-ERG)

Integrated Stem Cell Signature and Cytomolecular Risk Determination in Pediatric Acute Myeloid Leukemia

Genome and Transcriptome Profiling of Monosomy 7 AML Defines Novel Risk and Therapeutic Cohorts

Discovery of Novel IL3RA (CD123) Isoforms By Long Read Transcriptomics, Heterogeneous Expression Among AML Patient Cohorts and the Implications for Anti-CD123 Therapeutics

Whole Genome Sequencing Identifies Small Deletions in Ribosomal Genes Causing Diamond Blackfan Anemia

Structural Variants Involving MLLT10/AF10 Are Associated with Adverse Outcome in AML Regardless of the Partner Gene - a COG/Tpaml Study

A Distinct Oncofetal B-Cell Transcriptional Program Is Activated in Infant Acute Myeloid Leukemia and Reveals Novel Therapeutic Strategies

Long Non-Coding RNAs (lncRNAs) Are Highly Associated with Disease Characteristics and Outcome in Pediatric Acute Myeloid Leukemia - a COG and Tpaml Study

Phenotypes of Diamond Blackfan Anemia Patients with RPL35A Haploinsufficiency Due to 3q29 Deletion Compared with RPL35A Single Nucleotide Variants or Small Insertion/Deletions

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American Society of Hematology

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