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Journal Articles

Comparative Somatic Mutational Profiling of CD34+ Hematopoietic Precursors (HSC) and Circulating Endothelial Cells (CEC) in Patients with Primary Myelofibrosis (PMF)

Mirko Farina, MD, Simona Bernardi, PhD, Nicola Polverelli, Camilla Zanaglio, PhD, Michele Malagola, MD, Federica Re, Federica Cattina, MD PhD, Mariella D'Adda, MD, Giuseppe Rossi, Tatiana Zollner, MD, Andrew Dunbar, MD, Ross L. Levine, MD, Domenico Russo, MD

Blood (2019) 134 (Supplement_1): 1684.

https://doi.org/10.1182/blood-2019-127451

Published: 2019

Journal Articles

Identification of a Novel Mutation Predisposing to Familial AML and MDS Syndrome By a NGS Approach

Simona Bernardi, PhD, Camilla Zanaglio, PhD, Elif Dereli Eke, PhDStudent, Federica Cattina, MD PhD, Mirko Farina, MD, Stefania Masneri, PhD, Benedetta Rambaldi, MD, Francesca Schieppati, MD, Alessandro Turra, MD, Nicola Polverelli, MD, Enrico Morello, MD, Michele Malagola, MD, Domenico Russo, MD

Blood (2018) 132 (Supplement 1): 4387.

https://doi.org/10.1182/blood-2018-99-109927

Published: 2018

Journal Articles

ANTI-CMV Immunoglobulins in Association with ANTI-CMV Drugs in Patients with Hematological Malignancies Submitted to Allogeneic STEM CELL Transplantation: A MULTI-Center Retrospective Experience

Blood (2018) 132 (Supplement 1): 3381.

https://doi.org/10.1182/blood-2018-99-110252

Published: 2018

Journal Articles

Comparative Study on Fresenius-ATG Versus Thymoglobuline-ATG for the Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Stem Cell Transplantation from Matched Unrelated Donor: A Single Center Experience on 76 Patients

Nicola Polverelli, MD PhDstudent, Michele Malagola, MD PhD, Alessandro Turra, MD, Cristina Skert, MD, Federica Cattina, MD PhD, Benedetta Rambaldi, MD, Rossella Ribolla, MD, Valeria Cancelli, MD, Francesca Schieppati, MD, Marta Bonetti, MD, Simona Bernardi, PhD, Simone Perucca, PhD, Camilla Zanaglio, Domenico Russo, MD

Blood (2016) 128 (22): 4601.

https://doi.org/10.1182/blood.V128.22.4601.4601

Published: 2016

Journal Articles

Incidence and Outcome of Bacterial Blood Stream Infections in Allotransplanted Patients: Rethinking the Role of Fluoroquinolone Prophylaxis

Benedetta Rambaldi, MD, Michele Malagola, MD PhD, Giuseppe Ravizzola, MD, Giorgio Giannetta, Nicola Polverelli, MD PhDstudent, Cristina Skert, MD, Alessandro Turra, MD, Valeria Cancelli, MD, Federica Cattina, MD PhD, Francesca Schieppati, MD, Arnaldo Caruso, MD, Domenico Russo, MD

Blood (2016) 128 (22): 2223.

https://doi.org/10.1182/blood.V128.22.2223.2223

Published: 2016

Journal Articles

Assessment of BCR-ABL1 Transcript Levels By Digital PCR (dPCR) in CML Patients who Achieved a Deep Molecular Response (DMR: MR 4.0 , MR 4.5 And MR 5.0 ) with Tkis May Improve the Detection of Minimal Residual Disease (MRD) and the Selection of Patients for Treatment Free Remission (TFR)

Blood (2016) 128 (22): 3096.

https://doi.org/10.1182/blood.V128.22.3096.3096

Published: 2016

Journal Articles

Parameters of Protein Metabolism and Thyroid Function As Predictors in a Scoring System for Acute and Chronic Graft-Versus-Host Disease

Cristina Skert, MD, Alessandro Turra, Michele Malagola, Simone Perucca, Valeria Cancelli, Rosa Daffini, Rossella Ribolla, Cesare Bergonzi, Carla Filì, MD, Chiara Pagani, MD, Andrea Di Palma, Federica Cattina, MD PhD, Simona Bernardi, Domenico Russo, MD PhD

Blood (2014) 124 (21): 3932.

https://doi.org/10.1182/blood.V124.21.3932.3932

Published: 2014

Journal Articles

Patterns of Lymphocyte Subsets and Index of Bone Marrow Output (KRECs) Correlate Differently with Graft-Versus-Host Disease and Relapse

Cristina Skert, MD, Simone Perucca, Luisa Imberti, Marco Chiarini, MSc, Michele Malagola, Carla Filì, MD, Cesare Bergonzi, Rossella Ribolla, Valeria Cancelli, Alessandro Turra, Federica Cattina, MD PhD, Andrea Di Palma, Domenico Russo, MD PhD

Blood (2014) 124 (21): 3933.

https://doi.org/10.1182/blood.V124.21.3933.3933

Published: 2014

Journal Articles

Ultra-Deep Sequencing Strategy Is a Precious Tool to Find Small Clones Harbouring FLT3 Mutations in AML Patients

Elisa Zuffa, PhD, Eugenia Franchini, Cristina Papayannidis, MD PhD, Carmen Baldazzi, PhD, Nicoletta Testoni, PhD, Federica Cattina, MD PhD, Maria Chiara Abbenante, Stefania Paolini, Ilaria Iacobucci, PhD, Viviana Guadagnuolo, Antonella Padella, Giorgia Simonetti, PhD, Emanuela Ottaviani, Giovanni Martinelli, MD

Blood (2014) 124 (21): 1040.

https://doi.org/10.1182/blood.V124.21.1040.1040

Published: 2014

Journal Articles

WT1 Monitoring of Minimal Residual Disease (MRD) in Patients with Acute Myeloid Leukemia

Michele Malagola, Crisitina Skert, Enrico Morello, MD, Francesca Antoniazzi, MD, Erika Borlenghi, MD, Alessandro Turra, Chiara Pagani, MD, Rossella Ribolla, Valeria Cancelli, Federica Cattina, MD PhD, Elisa Alghisi, Simona Bernardi, Simone Perucca, Andrea Di Palma, Giuseppina Ruggeri, Giuseppe Rossi, Luigi Caimi, Domenico Russo, MD

Blood (2014) 124 (21): 3695.

https://doi.org/10.1182/blood.V124.21.3695.3695

Published: 2014

Journal Articles

Ultra-Deep Amplicon Sequencing Using Roche 454 Technology Allows High Sensitivity Bcr-Abl Kinase Domain Mutation Screening and Anticipates Emerging Mutations Leading to Resistance to Tyrosine Kinase Inhibitors in Philadelphia-Positive Leukemia Patients,

Simona Soverini, Caterina De Benedittis, Alessandra Gnani, Ilaria Iacobucci, PhD, Domenico Russo, Federica Cattina, MD, Fausto Castagnetti, Gabriele Gugliotta, Cristina Papayannidis, Antonella Vitale, Loredana Elia, Robin Foà, Francesca Palandri, Annalisa Lonetti, Maria Teresa Bochicchio, Sandra Durante, Gianantonio Rosti, MD, Michele Baccarani, MD, Giovanni Martinelli

Blood (2011) 118 (21): 3775.

https://doi.org/10.1182/blood.V118.21.3775.3775

Published: 2011

Journal Articles

Establishing a New Zebrafish Model to Study Malignant Transformation in Myeloproliferative Disorders

Elisa Alghisi, Michele Malagola, Cristina Santoriello, Cristina Skert, MD, Carla Filì, Cesare Bergonzi, Annalisa Peli, Alessandro Turra, Valeria Cancelli, Rossella Ribolla, Federica Cattina, MD, Marina Mione, Domenico Russo

Blood (2011) 118 (21): 4711.

https://doi.org/10.1182/blood.V118.21.4711.4711

Published: 2011

Journal Articles

TP53 Alterations Including Missense Mutations, Aberrant Exon-Junctions and Internal Intron Retentions Are Frequent and May Contribute to MDM2 Antagonist-Resistance in B-Acute Lymphoblastic leukemia

Ilaria Iacobucci, PhD, Anna Ferrari, Stefania Trino, Annalisa Lonetti, Cristina Papayannidis, Alberto Ferrarini, Luca Venturini, Maria Chiara Abbenante, Sarah Parisi, Federica Cattina, MD, Simona Soverini, Stefania Paolini, Domenico Russo, Marco Vignetti, Fabrizio Pane, Pellegrino Musto, Massimo Delledonne, Michele Baccarani, MD, Giovanni Martinelli, MD

Blood (2011) 118 (21): 1484.

https://doi.org/10.1182/blood.V118.21.1484.1484

Published: 2011

Journal Articles

Gas1 and Kif27 Genes Are Strongly up-Regulated Biomarkers of Hedgehog Inhibition (PF-04449913) on Leukemia Stem Cells in Phase I Acute Myeloid Leukemia and Chronic Myeloid Leukemia Treated Patients

Blood (2011) 118 (21): 1535.

https://doi.org/10.1182/blood.V118.21.1535.1535

Published: 2011

Journal Articles

The Novel Small Molecule Chk1/Chk2 Inhibitor PF-0477736 (Pfizer) Is Highly Active As Single Agent in Philadelphia-Positive Acute Lymphoblastic Leukemia (Ph+ ALL)

Blood (2011) 118 (21): 76.

https://doi.org/10.1182/blood.V118.21.76.76

Published: 2011

Journal Articles

Long Term Follow-up of Ph+ CML Patients Achieving Complete Cytogenetic Response (CCgR) with Interferon Based Therapy - GIMEMA Protocol CML0509

Domenico Russo, Giuliana Alimena, Chiara Colombi, Massimo Breccia, Simona Soverini, Ilaria Iacobucci, PhD, Federica Cattina, MD, Giovanni Martinelli, MD, Nicoletta Testoni, Anna Marina Liberati, Viviana Appolloni, Mario Tiribelli, Renato Fanin, Felicetto Ferrara, MD, Mario Annunziata, MD, Elena Trabacchi, Daniele Vallisa, MD, Antonio De Vivo, Fausto Castagnetti, Miriam Fogli, Sandra Durante, Francesco Di Raimondo, MD, Fabio Stagno, A. M. Carella, G. Pica, Alessandra Iurlo, M.D., Tommaso Radice, Patrizia Pregno, MD, Umberto Vitolo, MD, Elisabetta Abruzzese, Paolo de Fabritiis, Maurizio Longinotti, MD, Simonetta Pardini, Caterina Musolino, MD, Sabina Russo, Marco Gobbi, MD, Ivana Pierri, Gianluca Gaidano, Monia Lunghi, M.D., Giuseppe Visani, Sara Barulli, Mario Cazzola, Serena Merante, Cristina Skert, MD, Michele Malagola, Gianantonio Rosti, MD, Michele Baccarani, MD

Blood (2011) 118 (21): 786.

https://doi.org/10.1182/blood.V118.21.786.786

Published: 2011

Journal Articles

PF-04449913 Reverts Multi Drug Resistance (MDR) by a Strong Down-Regulation of ABCA2 and BCL2 on Leukemia Stem Cells in Phase I Acute Myeloid Leukemia and Chronic Myeloid Leukemia Treated Patients

Blood (2011) 118 (21): 1429.

https://doi.org/10.1182/blood.V118.21.1429.1429

Published: 2011

Journal Articles

The Small Molecule CHK1/CHK2 Inhibitor PF-0477736 (Pfizer) Demonstrates Single Agent Activity and Synergizes with Chemotherapy in Diffuse Large B-Cell Lymphoma

Enrico Derenzini, MD, Ilaria Iacobucci, PhD, Elisa Brighenti, PhD, Federica Cattina, MD, Richard Eric Davis, MD, Stefano Pileri, MD, Giovanni Martinelli, MD, Michele Baccarani, MD, Pier Luigi Zinzani, MD

Blood (2011) 118 (21): 2732.

https://doi.org/10.1182/blood.V118.21.2732.2732

Published: 2011

Journal Articles

ARF Loss, a Negative Prognostic Factor in Philadelphia-Positive Acute Lymphoblastic Leukemia, May Be Efficiently Overcome by the Small Molecule MDM2 Antagonist RG7112

Ilaria Iacobucci, PhD, Federica Cattina, MD, Silvia Pomella, Annalisa Lonetti, Anna Ferrari, Cristina Papayannidis, Stefania Trino, Daniela Erriquez, Viviana Guadagnuolo, Emanuela Ottaviani, Serena Formica, Simona Soverini, Francesca Paoloni, Marco Vignetti, Domenico Russo, Giovanni Perini, Michele Baccarani, MD, Giovanni Martinelli, MD

Blood (2011) 118 (21): 2574.

https://doi.org/10.1182/blood.V118.21.2574.2574

Published: 2011

Journal Articles

Azacitidine Low-Dose Schedule In Low-Risk Myelodysplastic Syndromes. Preliminary Results of a Multicenter Phase II Study

Blood (2010) 116 (21): 4029.

https://doi.org/10.1182/blood.V116.21.4029.4029

Published: 2010

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Comparative Somatic Mutational Profiling of CD34+ Hematopoietic Precursors (HSC) and Circulating Endothelial Cells (CEC) in Patients with Primary Myelofibrosis (PMF)

Identification of a Novel Mutation Predisposing to Familial AML and MDS Syndrome By a NGS Approach

ANTI-CMV Immunoglobulins in Association with ANTI-CMV Drugs in Patients with Hematological Malignancies Submitted to Allogeneic STEM CELL Transplantation: A MULTI-Center Retrospective Experience

Comparative Study on Fresenius-ATG Versus Thymoglobuline-ATG for the Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Stem Cell Transplantation from Matched Unrelated Donor: A Single Center Experience on 76 Patients

Incidence and Outcome of Bacterial Blood Stream Infections in Allotransplanted Patients: Rethinking the Role of Fluoroquinolone Prophylaxis

Assessment of BCR-ABL1 Transcript Levels By Digital PCR (dPCR) in CML Patients who Achieved a Deep Molecular Response (DMR: MR 4.0 , MR 4.5 And MR 5.0 ) with Tkis May Improve the Detection of Minimal Residual Disease (MRD) and the Selection of Patients for Treatment Free Remission (TFR)

Parameters of Protein Metabolism and Thyroid Function As Predictors in a Scoring System for Acute and Chronic Graft-Versus-Host Disease

Patterns of Lymphocyte Subsets and Index of Bone Marrow Output (KRECs) Correlate Differently with Graft-Versus-Host Disease and Relapse

Ultra-Deep Sequencing Strategy Is a Precious Tool to Find Small Clones Harbouring FLT3 Mutations in AML Patients

WT1 Monitoring of Minimal Residual Disease (MRD) in Patients with Acute Myeloid Leukemia

Ultra-Deep Amplicon Sequencing Using Roche 454 Technology Allows High Sensitivity Bcr-Abl Kinase Domain Mutation Screening and Anticipates Emerging Mutations Leading to Resistance to Tyrosine Kinase Inhibitors in Philadelphia-Positive Leukemia Patients,

Establishing a New Zebrafish Model to Study Malignant Transformation in Myeloproliferative Disorders

TP53 Alterations Including Missense Mutations, Aberrant Exon-Junctions and Internal Intron Retentions Are Frequent and May Contribute to MDM2 Antagonist-Resistance in B-Acute Lymphoblastic leukemia

Gas1 and Kif27 Genes Are Strongly up-Regulated Biomarkers of Hedgehog Inhibition (PF-04449913) on Leukemia Stem Cells in Phase I Acute Myeloid Leukemia and Chronic Myeloid Leukemia Treated Patients

The Novel Small Molecule Chk1/Chk2 Inhibitor PF-0477736 (Pfizer) Is Highly Active As Single Agent in Philadelphia-Positive Acute Lymphoblastic Leukemia (Ph+ ALL)

Long Term Follow-up of Ph+ CML Patients Achieving Complete Cytogenetic Response (CCgR) with Interferon Based Therapy - GIMEMA Protocol CML0509

PF-04449913 Reverts Multi Drug Resistance (MDR) by a Strong Down-Regulation of ABCA2 and BCL2 on Leukemia Stem Cells in Phase I Acute Myeloid Leukemia and Chronic Myeloid Leukemia Treated Patients

The Small Molecule CHK1/CHK2 Inhibitor PF-0477736 (Pfizer) Demonstrates Single Agent Activity and Synergizes with Chemotherapy in Diffuse Large B-Cell Lymphoma

ARF Loss, a Negative Prognostic Factor in Philadelphia-Positive Acute Lymphoblastic Leukemia, May Be Efficiently Overcome by the Small Molecule MDM2 Antagonist RG7112

Azacitidine Low-Dose Schedule In Low-Risk Myelodysplastic Syndromes. Preliminary Results of a Multicenter Phase II Study

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