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Serena Lavorgna
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Journal Articles

Validation of ELN2017 Risk Stratification in a Post-Hoc Analysis of the Prospective Biomarker-Based Gimema AML1310 Protocol

Raffaele Palmieri, MD, Francesco Buccisano, MD, Alfonso Piciocchi, MS, Valentina Arena, MS, Anna Candoni, Lorella MA Melillo, MD, Valeria Calafiore, Roberto Cairoli, MD, Paolo De Fabritiis, MD, Gabriella Storti, Prassede Salutari, MD, Francesco Lanza, MD, Giovanni Martinelli, MD, Mario Luppi, Saveria Capria, MD, Luca Maurillo, Maria Ilaria Del Principe, Giovangiacinto Paterno, Maria Teresa Voso, MD, Tiziana Ottone, Serena Lavorgna, Paola Fazi, MD, Marco Vignetti, MD, William Arcese, MD PhD, Adriano Venditti, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–35.
https://doi.org/10.1182/blood-2020-139773
Published: 2020
Journal Articles

Clinical Relevance of- Limit of Detection (LOD) - Limit of Quantification (LOQ) - Based Flow Cytometry Approach for Measurable Residual Disease (MRD) Assessment in Acute Myeloid Leukemia (AML)

Raffaele Palmieri, MD, Alfonso Piciocchi, Valentina Arena, MS, Luca Maurillo, Maria Ilaria Del Principe, Giovangiacinto Paterno, Tiziana Ottone, Mariadomenica Divona, Serena Lavorgna, Maria Irno Consalvo, Consuelo Conti, Cristina Attrotto, Daniela Fraboni, Maria Teresa Voso, MD, William Arcese, MD PhD, Adriano Venditti, MD, Francesco Buccisano, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-139557
Published: 2020
Journal Articles

Multiparametric Flow-Cytometry Is a Reliable Tool for Measurable Residual Disease Assessment and Risk-Stratification of FLT3-Mutated AML Patients

Raffaele Palmieri, MD, Luca Maurillo, Alfonso Piciocchi, Maria Ilaria Del Principe, Valentina Arena, Stefano Soddu, Ambra Di Veroli, MD, Giovangiacinto Paterno, Eleonora De Bellis, Raffaella Cerretti, Gottardo De Angelis, Benedetta Mariotti, Tiziana Ottone, Mariadomenica Divona, Serena Lavorgna, Maria Irno Consalvo, Consuelo Conti, Cristina Attrotto, Daniela Fraboni, William Arcese, Maria Teresa Voso, MD, Adriano Venditti, Francesco Buccisano, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5083.
https://doi.org/10.1182/blood-2019-129184
Published: 2019
Journal Articles

Mutational Profile of Leukemic Stem Cells in FLT3 -ITD Mutated AML

Tiziana Ottone, Serena Travaglini, Valentina Alfonso, PhD, Daniela Angelini, PhD, Gisella Guerrera, PhD, Serena Lavorgna, Mariadomenica Divona, Anna Maria Nardozza, Antonio Cristiano, Maria irno Consalvo, PhD, Marco de Bardi, PhD, Benedetta Neri, MD, Francesco Marchesi, Carmelo Gurnari, MD, Giovangiacinto Paterno, Vincenza Martini, MD, Luca Battistini, MD, PhD, Adriano Venditti, Francesco Buccisano, MD, William Arcese, Francesco Lo-Coco, Maria Teresa Voso, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1458.
https://doi.org/10.1182/blood-2019-126040
Published: 2019
Journal Articles

GIMEMA AML1310 trial of risk-adapted, MRD-directed therapy for young adults with newly diagnosed acute myeloid leukemia

Clinical Trials & Observations
Adriano Venditti, Alfonso Piciocchi, Anna Candoni, Lorella Melillo, Valeria Calafiore, Roberto Cairoli, Paolo de Fabritiis, Gabriella Storti, Prassede Salutari, Francesco Lanza, Giovanni Martinelli, Mario Luppi, Patrizio Mazza, Maria Paola Martelli, Antonio Cuneo, Francesco Albano, Francesco Fabbiano, Agostino Tafuri, Anna Chierichini, Alessia Tieghi, Nicola Stefano Fracchiolla, Debora Capelli, Robin Foà, Caterina Alati, Edoardo La Sala, Paola Fazi, Marco Vignetti, Luca Maurillo, Francesco Buccisano, Maria Ilaria Del Principe, Maria Irno-Consalvo, Tiziana Ottone, Serena Lavorgna, Maria Teresa Voso, Francesco Lo-Coco, William Arcese, Sergio Amadori
Journal: Blood
Blood (2019) 134 (12): 935–945.
https://doi.org/10.1182/blood.2018886960
Published: 2019
Includes: Supplemental data
Journal Articles

Ratify (Alliance 10603): Prognostic Impact of FLT3 tyrosine Kinase Domain (TKD) and NPM1 Mutation Status in Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) Treated with Midostaurin or Placebo Plus Standard Chemotherapy

Maria Teresa Voso, Richard A. Larson, MD, Thomas Prior, Guido Marcucci, Dan Jones, MD PhD, Jürgen Krauter, MD, Michael Heuser, MD, Serena Lavorgna, PhD, Josep Nomdedeu, MD PhD, Susan M. Geyer, PhD, Rebecca Klisovic, MD, Andrew H Wei, MBBS, PhD, Jorge Sierra, MD, Miguel A. Sanz, MD, Joseph M. Brandwein, MD FRCPC, Theo M de Witte, MD, Joop H. Jansen, Dietger Niederweiser, Frederick R. Appelbaum, MD, Bruno C. Medeiros, MD, Martin S. Tallman, MD, Richard F. Schlenk, MD, Arnold Ganser, MD, Sergio Amadori, MD, Yuan Cheng, PhD, Insa Gathmann, Eva Tiecke, PhD, Christian Thiede, MD, Konstanze Döhner, MD, Hartmut Döhner, MD, Richard M. Stone, MD, Clara D. Bloomfield, MD, Francesco Lo-Coco, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2668.
https://doi.org/10.1182/blood-2018-99-114318
Published: 2018
Journal Articles

FLT3 mutation Assay Laboratory Cross Validation: Results from the CALGB 10603/Ratify Trial in Patients with Newly Diagnosed FLT3 -Mutated Acute Myeloid Leukemia (AML)

Christian Thiede, MD, Thomas W Prior, MD, Serena Lavorgna, PhD, Jürgen Krauter, MD, Eva Barragán, Josep Nomdedeu, MD PhD, Joop H. Jansen, Andrew H Wei, MBBS, PhD, Weiqiang Zhao, MD PhD, Xiaohong Li, Celine Pallaud, PhD, Eva Tiecke, PhD, Richard A. Larson, MD, Clara D. Bloomfield, MD, Hartmut Döhner, MD, Gerhard Ehninger, MD, Richard M. Stone, MD, Konstanze Döhner, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2800.
https://doi.org/10.1182/blood-2018-99-112127
Published: 2018
Journal Articles

Longitudinal Detection of DNMT3A R882H Transcripts in Patients with Acute Myeloid Leukemia

Tiziana Ottone, PhD, Valentina Alfonso, BS, Licia Iaccarino, BS, Syed Khizer Hasan, PhD, Melissa Mancini, PhD, Mariadomenica Divona, BS, Serena Lavorgna, PhD, Laura Cicconi, Paola Panetta, PhD, Luca Maurillo, MD, PhD, Maria Ilaria Del Principe, Maria irno Consalvo, PhD, Luca Franceschini, MD, PhD, Daniela Angelini, PhD, Luca Battistini, MD, PhD, Gisella Guerrera, PhD, Marco de Bardi, PhD, Emiliano Fabiani, PhD, Giulia Falconi, PhD, William Arcese, MD, Sergio Amadori, MD, Francesco Buccisano, MD, Adriano Venditti, MD, Maria Teresa Voso, MD, Francesco Lo Coco, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3959.
https://doi.org/10.1182/blood.V130.Suppl_1.3959.3959
Published: 2017
Journal Articles

Assessment of BCR-ABL1 Transcript Levels By Digital PCR (dPCR) in CML Patients who Achieved a Deep Molecular Response (DMR: MR 4.0 , MR 4.5 And MR 5.0 ) with Tkis May Improve the Detection of Minimal Residual Disease (MRD) and the Selection of Patients for Treatment Free Remission (TFR)

Bernardi Simona, Andrea Di Palma, Federica Cattina, MD PhD, Simone Perucca, PhD, Michele Malagola, MD PhD, Mario Tiribelli, MD, Erika Codarin, Maria Teresa Bochicchio, Dr., Giuseppina Ruggeri, Luca Franceschini, MD, Valeria Cancelli, MD, Fausto Castagnetti, MD, Simona Soverini, Miriam Fogli, Claudia Venturi, Dr., Serena Lavorgna, Chiara Pagani, MD, Cristina Skert, MD, Camilla Zanaglio, Alessandro Turra, Nicola Polverelli, Luigi Caimi, Giuseppe Rossi, MD, Maria Teresa Voso, MD, Gianantonio Rosti, MD, Giovanni Martinelli, MD Prof., Michele Baccarani, Domenico Russo, MD
Journal: Blood
Blood (2016) 128 (22): 3096.
https://doi.org/10.1182/blood.V128.22.3096.3096
Published: 2016
Journal Articles

The hidden genomic landscape of acute myeloid leukemia: subclonal structure revealed by undetected mutations

Margherita Bodini, Chiara Ronchini, Luciano Giacò, Anna Russo, Giorgio E. M. Melloni, Lucilla Luzi, Domenico Sardella, Sara Volorio, Syed K. Hasan, Tiziana Ottone, Serena Lavorgna, Francesco Lo-Coco, Anna Candoni, Renato Fanin, Eleonora Toffoletti, Ilaria Iacobucci, Giovanni Martinelli, Alessandro Cignetti, Corrado Tarella, Loris Bernard, Pier Giuseppe Pelicci, Laura Riva
Journal: Blood
Blood (2015) 125 (4): 600–605.
https://doi.org/10.1182/blood-2014-05-576157
Published: 2015
Includes: Supplemental data
Journal Articles

Results of the “Evaluation of NGS in AML-Diagnostics (ELAN)” Study – an Inter-Laboratory Comparison Performed in 10 European Laboratories

Christian Thiede, MD, Lars Bullinger, MD PhD, Jesús M Hernández-Rivas, MDPhD, Michael Heuser, MD, Claude Preudhomme, PhD, Steven Best, PhD, Dolors Colomer, PhD, Francesco Lo Coco, MD, Giovanni Martinelli, MD, Anna Schuh, MDPhD, Rocí­o Benito, PhD, Anna Dolnik, Anna Enjuanes, PhD, Sandrine Geffroy, Serena Lavorgna, PhD, Nicholas Lea, PhD, Joanne Mason, PhD, Emanuela Ottaviani, Anne Otto, Felicitas Thol, MD, Sabin Bhuju, Konstanze Döhner, MD, Christian Eberlein, PhD, Angela Hamblin, MDPhD, Olivier Nibourel, PhD, Tiziana Ottone, PhD, Maria Antonella Laginestra, Marta Pratcorona, MD PhD, Mónica del Rey, PhD, Felix Schlesinger, PhD
Journal: Blood
Blood (2014) 124 (21): 2374.
https://doi.org/10.1182/blood.V124.21.2374.2374
Published: 2014
Journal Articles

Cytogenetic and molecular diagnostic characterization combined to postconsolidation minimal residual disease assessment by flow cytometry improves risk stratification in adult acute myeloid leukemia

Clinical Trials & Observations
Francesco Buccisano, Luca Maurillo, Alessandra Spagnoli, Maria Ilaria Del Principe, Daniela Fraboni, Paola Panetta, Tiziana Ottone, Maria Irno Consalvo, Serena Lavorgna, Pietro Bulian, Emanuele Ammatuna, Daniela F. Angelini, Adamo Diamantini, Selenia Campagna, Licia Ottaviani, Chiara Sarlo, Valter Gattei, Giovanni Del Poeta, William Arcese, Sergio Amadori, Francesco Lo Coco, Adriano Venditti
Journal: Blood
Blood (2010) 116 (13): 2295–2303.
https://doi.org/10.1182/blood-2009-12-258178
Published: 2010
Includes: Supplemental data
Journal Articles

A monoclonal antibody against mutated nucleophosmin 1 for the molecular diagnosis of acute myeloid leukemias

Alicja M. Gruszka, Serena Lavorgna, Maria Irno Consalvo, Tiziana Ottone, Chiara Martinelli, Mario Cinquanta, Giuseppe Ossolengo, Giancarlo Pruneri, Francesco Buccisano, Mariadomenica Divona, Michele Cedrone, Emanuele Ammatuna, Adriano Venditti, Ario de Marco, Francesco Lo-Coco, Pier Giuseppe Pelicci
Journal: Blood
Blood (2010) 116 (12): 2096–2102.
https://doi.org/10.1182/blood-2010-01-266908
Published: 2010
Includes: Supplemental data
Journal Articles

Nucleophosmin Gene Mutations Exhibit High Spontaneous Apoptosis and Favorable Prognosis in Acute Myeloid Leukemia.

Giovanni Del Poeta, MD, Emanuele Ammatuna, M.D., Serena Zaza, Ph.D., Francesco Buccisano, M.D., Tiziana Ottone, Ph.D., Maria Ilaria Del Principe, M.D., Serena Lavorgna, Ph.D., Gianfranco Catalano, M.D., Luca Maurillo, M.D., Fabrizio Luciano, Ph.D., Paolo de Fabritiis, M.D., Adriano Venditti, M.D., Sergio Amadori, M.D., Francesco Lo Coco, M.D.
Journal: Blood
Blood (2007) 110 (11): 3480.
https://doi.org/10.1182/blood.V110.11.3480.3480
Published: 2007