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Journal Articles

Intracellular NAD + depletion enhances bortezomib-induced anti-myeloma activity

Antonia Cagnetta, Michele Cea, Teresa Calimeri, Chirag Acharya, Mariateresa Fulciniti, Yu-Tzu Tai, Teru Hideshima, Dharminder Chauhan, Mike Y. Zhong, Franco Patrone, Alessio Nencioni, Marco Gobbi, Paul Richardson, Nikhil Munshi, Kenneth C. Anderson

Blood (2013) 122 (7): 1243–1255.

https://doi.org/10.1182/blood-2013-02-483511

Published: 2013

Includes: Supplemental data

Journal Articles

Intracellular NAD + Depletion Enhances Bortezomib-Induced Myeloma Cytotoxicity

Antonia Cagnetta, MD, Michele Cea, MD, Chirag Acharya, MD, Teresa Calimeri, MD, Yu-Tzu Tai, PhD, Teru Hideshima, MD, PhD, Dharminder Chauhan, PhD, Franco Patrone, Marco Gobbi, MD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD

Blood (2012) 120 (21): 330.

https://doi.org/10.1182/blood.V120.21.330.330

Published: 2012

Journal Articles

Compromised Nuclear Sirtuins Activity Sensitizes BRCA-Proficient multiple Myeloma Cells to DNA Damage Agents

Michele Cea, MD, Antonia Cagnetta, MD, Aditya Munshi, Yu-Tzu Tai, PhD, Teru Hideshima, MD, PhD, Dharminder Chauhan, PhD, Franco Patrone, Marco Gobbi, MD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD

Blood (2012) 120 (21): 723.

https://doi.org/10.1182/blood.V120.21.723.723

Published: 2012

Journal Articles

Targeting NAD + salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition

Michele Cea, Antonia Cagnetta, Mariateresa Fulciniti, Yu-Tzu Tai, Teru Hideshima, Dharminder Chauhan, Aldo Roccaro, Antonio Sacco, Teresa Calimeri, Francesca Cottini, Jana Jakubikova, Sun-Young Kong, Franco Patrone, Alessio Nencioni, Marco Gobbi, Paul Richardson, Nikhil Munshi, Kenneth C. Anderson

Blood (2012) 120 (17): 3519–3529.

https://doi.org/10.1182/blood-2012-03-416776

Published: 2012

Includes: Supplemental data

Journal Articles

Targeting NAD + Salvage Pathway Induces Autophagy in Multiple Myeloma Cells

Michele Cea, MD, Antonia Cagnetta, MD, Yu-Tzu Tai, PhD, Mariateresa Fulciniti, PhD, Teru Hideshima, MD, PhD, Dharminder Chauhan, PhD, Sun-Young Kong, MD, PhD, Teresa Calimeri, M.D., Francesca Cottini, MD, Jana Jakubikova, PhD, Alessio Nencioni, Marco Gobbi, MD, Franco Patrone, Kenneth C. Anderson, MD

Blood (2011) 118 (21): 2920.

https://doi.org/10.1182/blood.V118.21.2920.2920

Published: 2011

Journal Articles

Hedgehog Signaling Is Useful as a Novel Molecular Marker for Predicting Relapse and Resistance During Chronic Myeloid Leukemia Treatment.

Michele Cea, Antonia Cagnetta, Gabriella Cirmena, Anna Garuti, Ilaria Rocco, Claudia Palermo, Ivana Pierri, Marco Gobbi, MD, Alberto Ballestrero, Alessio Nencioni, Franco Patrone, Angelo Michele Carella

Blood (2010) 116 (21): 1215.

https://doi.org/10.1182/blood.V116.21.1215.1215

Published: 2010

Journal Articles

Catastrophic NAD + Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE.

Santina Bruzzone, Ph.D., Floriana Fruscione, Sara Morando, Alessandro Poggi, Anna Garuti, Martina Selmo, Tiziana Ferrando, Federica Benvenuto, Michele Cea, MD, Debora Soncini, Eva Moran, Ph.D., Ilaria Rocco, Gabriella Cirmena, Gabriele Zoppoli, MD, Alberto Ballestrero, MD, Ph.D., Bernard Sordat, Franco Patrone, Antonio Uccelli, Alessio Nencioni, MD, Ph.D.

Blood (2009) 114 (22): 4732.

https://doi.org/10.1182/blood.V114.22.4732.4732

Published: 2009

Journal Articles

Finding of Kinase Domain Mutations at Diagnosis IN PATIENTS with Chronic PHASE Chronic Myeloid Leukemia (CP-CML) MAY Identify Those at High RISK of Disease Progression.

Angelo Michele Carella, Gabriella Cirmena, Gioacchino Catania, Gianmatteo Pica, Germana Beltrami, Alberto Ballestrero, Franco Patrone, Anna Garuti

Blood (2009) 114 (22): 4251.

https://doi.org/10.1182/blood.V114.22.4251.4251

Published: 2009

Journal Articles

Deacetylase Inhibitor Cocktails Provide Striking Synergistic Interactions in Human Leukemia Cells.

Michele Cea, MD, Antonia Cagnetta, Floriana Fruscione, Santina Bruzzone, Ph.D., Gabriele Zoppoli, MD, Anna Garuti, Eva Moran, Ph.D., Valentina Grillo, Fabio Ferrando, Salvatore Casciaro, Ivana Pierri, Marco Gobbi, MD, Alberto Ballestrero, MD, Ph.D., Franco Patrone, MD, Ph.D., Alessio Nencioni, MD, Ph.D.

Blood (2009) 114 (22): 4404.

https://doi.org/10.1182/blood.V114.22.4404.4404

Published: 2009

Journal Articles

Potent Synergistic Activity of the NAD+ Synthesis Inhibitor APO866 and of the Apoptosis Inducer TRAIL in in Vitro and Ex Vivo Cellular Models of Non Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia.

Blood (2009) 114 (22): 2733.

https://doi.org/10.1182/blood.V114.22.2733.2733

Published: 2009

Journal Articles

APO866 activity in hematologic malignancies: a preclinical in vitro study

Michele Cea, Gabriele Zoppoli, Santina Bruzzone, Floriana Fruscione, Eva Moran, Anna Garuti, Ilaria Rocco, Gabriella Cirmena, Salvatore Casciaro, Francesca Olcese, Ivana Pierri, Antonia Cagnetta, Fabio Ferrando, Riccardo Ghio, Marco Gobbi, Alberto Ballestrero, Franco Patrone, Alessio Nencioni

Blood (2009) 113 (23): 6035–6037.

https://doi.org/10.1182/blood-2009-03-209213

Published: 2009

Journal Articles

Regulation of Dendritic Cell Function by Histone Deacetylase Inhibitors.

Julia Beck, Alessio Nencioni, MD, Frank Grünebach, PhD, Anita Bringmann, Lothar Kanz, MD, Franco Patrone, MD, Alberto Ballestrero, MD, Peter Brossart, MD

Blood (2006) 108 (11): 930.

https://doi.org/10.1182/blood.V108.11.930.930

Published: 2006

Journal Articles

Proteasome Inhibitors Affect the Function of Human Dendritic Cells and Induce Caspase-Mediated Apoptosis.

Karin von Schwarzenberg, Alessio Nencioni, MD, Anita Bringmann, Lothar Kanz, MD, Franco Patrone, MD, Alberto Ballestrero, MD, Peter Brossart, MD

Blood (2005) 106 (11): 2229.

https://doi.org/10.1182/blood.V106.11.2229.2229

Published: 2005

Journal Articles

The Persistence of p190 BCR-ABL Transcripts Is Associated with Lower Probability of Molecular Response to Imatinib in Early and Late Chronic Phase CML Patients.

Anna Garuti, PhD, Adalberto Ibatici, MD, Gabriella Cirmena, PhD, Maurizio Miglino, MD, Riccardo Varaldo, MD, Colombo Nicoletta, PhD, Roberta Grasso, PhD, Sarah Pozzi, PhD, Marina Podesta, PhD, Marco Gobbi, MD, Mario Sessarego, MD, Franco Patrone, MD, Francesco Frassoni, MD

Blood (2005) 106 (11): 3282.

https://doi.org/10.1182/blood.V106.11.3282.3282

Published: 2005

Journal Articles

Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis

Alessio Nencioni, Fei Hua, Christopher P. Dillon, Rayka Yokoo, Christoph Scheiermann, Mike H. Cardone, Eleonora Barbieri, Ilaria Rocco, Anna Garuti, Sebastian Wesselborg, Claus Belka, Peter Brossart, Franco Patrone, Alberto Ballestrero

Blood (2005) 105 (8): 3255–3262.

https://doi.org/10.1182/blood-2004-10-3984

Published: 2005

Journal Articles

Reduced Intensity Conditioning Regimen for Allografting Following Cytoreductive Autografting in Metastatic Breast Cancer.

A.M. Carella, MD, Germana Beltrami, MD, Maria T. Corsetti, MD, Potito Scalzulli, MD, Michele Carella, MD, Roberta Gonella, MD, Alberto Ballestreo, MD, Franco Patrone, MD

Blood (2004) 104 (11): 5129.

https://doi.org/10.1182/blood.V104.11.5129.5129

Published: 2004

NARROW

Intracellular NAD + depletion enhances bortezomib-induced anti-myeloma activity

Intracellular NAD + Depletion Enhances Bortezomib-Induced Myeloma Cytotoxicity

Compromised Nuclear Sirtuins Activity Sensitizes BRCA-Proficient multiple Myeloma Cells to DNA Damage Agents

Targeting NAD + salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition

Targeting NAD + Salvage Pathway Induces Autophagy in Multiple Myeloma Cells

Hedgehog Signaling Is Useful as a Novel Molecular Marker for Predicting Relapse and Resistance During Chronic Myeloid Leukemia Treatment.

Catastrophic NAD + Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE.

Finding of Kinase Domain Mutations at Diagnosis IN PATIENTS with Chronic PHASE Chronic Myeloid Leukemia (CP-CML) MAY Identify Those at High RISK of Disease Progression.

Deacetylase Inhibitor Cocktails Provide Striking Synergistic Interactions in Human Leukemia Cells.

Potent Synergistic Activity of the NAD+ Synthesis Inhibitor APO866 and of the Apoptosis Inducer TRAIL in in Vitro and Ex Vivo Cellular Models of Non Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia.

APO866 activity in hematologic malignancies: a preclinical in vitro study

Regulation of Dendritic Cell Function by Histone Deacetylase Inhibitors.

Proteasome Inhibitors Affect the Function of Human Dendritic Cells and Induce Caspase-Mediated Apoptosis.

The Persistence of p190 BCR-ABL Transcripts Is Associated with Lower Probability of Molecular Response to Imatinib in Early and Late Chronic Phase CML Patients.

Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis

Reduced Intensity Conditioning Regimen for Allografting Following Cytoreductive Autografting in Metastatic Breast Cancer.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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