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Journal Articles

Treg depletion supercharges ASCT power

Heiko Bruns

Blood (2024) 143 (16): 1562–1563.

https://doi.org/10.1182/blood.2024024075

Published: 2024

Journal Articles

CAR-T Cell Therapy in Patients with Refractory Systemic Autoimmune Diseases Exhibits Less Inflammation, Toxicities and Different Cellular Dynamics Compared to Patients with B Cell Lymphoma

Blood (2023) 142 (Supplement 1): 6871.

https://doi.org/10.1182/blood-2023-188830

Published: 2023

Journal Articles

Detection of Signature Double-Negative T Cells Is a Reliable Marker for ALPS Associated with FAS Mutation

Nina Eisenhauer, Maurizio Miano, Nora Naumann-Bartsch, Joerg Leyh, Paola Terranova, Claas Hinze, Michael Aigner, Helmut Wittkowski, Heiko Bruns, Stephan Ehl, Markus Metzler, Peter Arkwright, Andreas Mackensen, Anne Rensing-Ehl, Simon Voelkl

Blood (2022) 140 (Supplement 1): 11194.

https://doi.org/10.1182/blood-2022-168550

Published: 2022

Journal Articles

Sars-Cov-2 Vaccine-Induced Cellular and Humoral Immunity in Patients after CD19.CAR-T Cell Therapy

Hannah Reimann, Anita Natalie Kremer, Viktoria Blumenberg, Katja Schmidt, Michael Aigner, Andreas Kremer, Matthias Tenbusch, Heiko Bruns, Thomas Harrer, Georg Schett, Fabian Mueller, Andreas Mackensen, Marion Subklewe, Simon Voelkl

Blood (2022) 140 (Supplement 1): 10279–10280.

https://doi.org/10.1182/blood-2022-165968

Published: 2022

Journal Articles

Blocking the CD47-Sirpa Axis Enhances Tafasitamab-Mediated Phagocytosis

Blood (2022) 140 (Supplement 1): 9292–9293.

https://doi.org/10.1182/blood-2022-159955

Published: 2022

Journal Articles

Extracellular vesicles and PD-L1 suppress macrophages, inducing therapy resistance in TP53 -deficient B-cell malignancies

Blood (2022) 139 (25): 3617–3629.

https://doi.org/10.1182/blood.2021014007

Published: 2022

Includes: Supplemental data

Journal Articles

β 2 -m - a Trigger for NLRP3 Inflammasome Activation within Macrophages Promoting Multiple Myeloma Cell Proliferation

Daniel Hofbauer, Dimitrios Mougiakakos, MD, Maike Büttner-Herold, Frank Neumann, PhD, Jens Nolting, Savita Bisht, Robert Zeiser, MD, Shaima'A Hamarsheh, MSc,BSc, Stefano Ricagno, PhD, Mario Zaiss, Martin Eberhardt, Martin Boettcher, PhD, Katrin Bitterer, Andreas Mackensen, MD, Heiko Bruns, PhD

Blood (2019) 134 (Supplement_1): 2314.

https://doi.org/10.1182/blood-2019-123958

Published: 2019

Journal Articles

Mechanistic Characterization of Tafasitamab-Mediated Antibody-Dependent Cellular Phagocytosis Alone or in Combination with Lenalidomide

Dimitrios Mougiakakos, MD, Simon Voelkl, PhD, Christian Bach, Andrej Stoll, Katrin Bitterer, Fabian Beier, MD, Jan Endell, Rainer Boxhammer, Jörg Thomas Bittenbring, MD, Andreas Mackensen, MD, Heiko Bruns, PhD

Blood (2019) 134 (Supplement_1): 4064.

https://doi.org/10.1182/blood-2019-124886

Published: 2019

Journal Articles

Microenvironmental Triggers Induce a Chemoresistant, Differentiated Subset of S100A8/A9 high AML Cells Via the Jak/STAT3 Signaling Axis

Martin Boettcher, PhD, Konstantinos Panagiotidis, Kristin Mentz, Simon Voelkl, PhD, Heiko Bruns, PhD, Robert Slany, PhD, Andreas Mackensen, MD, Dimitrios Mougiakakos, MD

Blood (2019) 134 (Supplement_1): 2714.

https://doi.org/10.1182/blood-2019-129689

Published: 2019

Journal Articles

DNA Damage-Response Pathway in Lymphoma Determines Interactions with Macrophages By Altered PD-L1 Expression and Exosome Formation

Daniela Vorholt, PhD, Elena Izquierdo-Alvarez, PhD, Benedict Sackey, Jan Schmitz, Nadine Nickel, PhD, Stuart Blakemore, PhD, Gero Knittel, MSc, Christian Reinhardt, MD, Clemens-Martin Wendtner, Heiko Bruns, PhD, Michael Hallek, Christian Pallasch, MD

Blood (2018) 132 (Supplement 1): 275.

https://doi.org/10.1182/blood-2018-99-120264

Published: 2018

Journal Articles

Human Double-Negative Regulatory T Cells Modulate Effector Functions of Conventional T Cells By Selectively Blocking mTOR Signaling

Tabea Haug, Michael Aigner, PhD, Heiko Bruns, PhD, Moritz Peuser, Dorothea Gebhardt, Jana Berger, Florentine Koppitz, Andreas Mackensen, MD, Simon Voelkl

Blood (2018) 132 (Supplement 1): 2410.

https://doi.org/10.1182/blood-2018-99-112943

Published: 2018

Journal Articles

Role of N6-Methyladenosine (m6A) RNA Modification in Multiple Myeloma

Christian Bach, Magdalena Leffler, Cindy Flamann, Jan Kronke, Dimitrios Mougiakakos, Andreas Mackensen, MD, Heiko Bruns, PhD

Blood (2018) 132 (Supplement 1): 5601.

https://doi.org/10.1182/blood-2018-99-115820

Published: 2018

Journal Articles

Human Double-Degative Regulatory T Cells Modulate Differentiation and Function of Conventional T Cells By Disrupting mTOR Activity

Tabea Haug, Heiko Bruns, PhD, Michael Aigner, PhD, Andreas Mackensen, MD, Simon Voelkl, PhD

Blood (2017) 130 (Supplement 1): 3579.

https://doi.org/10.1182/blood.V130.Suppl_1.3579.3579

Published: 2017

Journal Articles

Human Double-Negative Regulatory T Cells Selectively Suppress mTOR Signaling and Metabolic Reprogramming of Conventional T Cells

Tabea Haug, Heiko Bruns, PhD, Michael Aigner, Andreas Mackensen, Simon Voelkl, PhD

Blood (2016) 128 (22): 3694.

https://doi.org/10.1182/blood.V128.22.3694.3694

Published: 2016

Journal Articles

Vitamin D Blocks CLL Cell-Mediated MDSC Induction

Dimitrios Mougiakakos, Heiko Bruns, PhD, Martin Böttcher, Mirjeta Qorraj, Mario Fabri, Jochen Dindorf, Leonhard Busch, Regina Jitschin, Andreas Mackensen, MD

Blood (2016) 128 (22): 4355.

https://doi.org/10.1182/blood.V128.22.4355.4355

Published: 2016

Journal Articles

the IKZF1-IRF4 Axis Regulates Macrophage Polarization and Macrophage-Mediated Anti-Tumor Immunity

Heiko Bruns, PhD, Dimitrios Mougiakakos, Christian Bach, Martin Böttcher, Joerg Thomas Bittenbring, MD, Maike Büttner, Kolja Gelse, Michael Rehli, Julia Wimmer, Fabian Beier, MD, Deniz Gezer, Jan Krönke, MD, Heidi Balzer, Stephanie Moi, Bernd Spriewald, MD, Andreas Mackensen, MD, Leonhard Busch

Blood (2016) 128 (22): 2514.

https://doi.org/10.1182/blood.V128.22.2514.2514

Published: 2016

Journal Articles

Indirect Presentation of Y-Chromosome Antigen Dby Is Regulated By Hsc70 and Mediated through CD63 Positive Exosomes

Sascha Kretschmann, Heiko Bruns, PhD, Ursula Schlötzer-Schrehardt, PhD, Andreas Mackensen, MD, Marieke Griffioen, PhD, Anita Kremer

Blood (2016) 128 (22): 3712.

https://doi.org/10.1182/blood.V128.22.3712.3712

Published: 2016

Journal Articles

Lenalidomide Enhances MOR202 Dependent Macrophage-Mediated Effector Functions Via the Vitamin D Pathway

Heiko Bruns, PhD, Regina Jitschin, PhDMD, Dimitrios Mougiakakos, Joerg Thomas Bittenbring, MD, Jens Nolting, Maike Büttner, Michael Rehli, PhD, Julia Wimmer, Frank Neumann, PhD, Christian Bach, Heidi Balzer, Stephanie Moi, Peter Brossart, MD, Armin Gerbitz, MD, Andreas Mackensen, MD

Blood (2015) 126 (23): 2203.

https://doi.org/10.1182/blood.V126.23.2203.2203

Published: 2015

Journal Articles

Vitamin D-Dependent Induction of Cathelicidin in Human Macrophages Results in Cytotoxicity Against High Grade B-Cell Lymphoma

Heiko Bruns, PhD, Maike Büttner, Mario Fabri, Dimitrios Mougiakakos, Joerg Thomas Bittenbring, MD, Shirin Pasemann, Frank Neumann, Anna Maurberger, Bettina Kempkes, Andreas Mackensen, Armin Gerbitz, MD

Blood (2014) 124 (21): 4108.

https://doi.org/10.1182/blood.V124.21.4108.4108

Published: 2014

Journal Articles

Transdifferentiation of Malignant B-Cells into Macrophages in a Murine Model of Burkitt´s Lymphoma

Heiko Bruns, PhD, Sebastian Mueller, Christian Bach, Shirin Pasemann, Anna Maurberger, Andreas Mackensen, Armin Gerbitz, MD

Blood (2014) 124 (21): 5406.

https://doi.org/10.1182/blood.V124.21.5406.5406

Published: 2014

NARROW

Treg depletion supercharges ASCT power

CAR-T Cell Therapy in Patients with Refractory Systemic Autoimmune Diseases Exhibits Less Inflammation, Toxicities and Different Cellular Dynamics Compared to Patients with B Cell Lymphoma

Detection of Signature Double-Negative T Cells Is a Reliable Marker for ALPS Associated with FAS Mutation

Sars-Cov-2 Vaccine-Induced Cellular and Humoral Immunity in Patients after CD19.CAR-T Cell Therapy

Blocking the CD47-Sirpa Axis Enhances Tafasitamab-Mediated Phagocytosis

Extracellular vesicles and PD-L1 suppress macrophages, inducing therapy resistance in TP53 -deficient B-cell malignancies

β 2 -m - a Trigger for NLRP3 Inflammasome Activation within Macrophages Promoting Multiple Myeloma Cell Proliferation

Mechanistic Characterization of Tafasitamab-Mediated Antibody-Dependent Cellular Phagocytosis Alone or in Combination with Lenalidomide

Microenvironmental Triggers Induce a Chemoresistant, Differentiated Subset of S100A8/A9 high AML Cells Via the Jak/STAT3 Signaling Axis

DNA Damage-Response Pathway in Lymphoma Determines Interactions with Macrophages By Altered PD-L1 Expression and Exosome Formation

Human Double-Negative Regulatory T Cells Modulate Effector Functions of Conventional T Cells By Selectively Blocking mTOR Signaling

Role of N6-Methyladenosine (m6A) RNA Modification in Multiple Myeloma

Human Double-Degative Regulatory T Cells Modulate Differentiation and Function of Conventional T Cells By Disrupting mTOR Activity

Human Double-Negative Regulatory T Cells Selectively Suppress mTOR Signaling and Metabolic Reprogramming of Conventional T Cells

Vitamin D Blocks CLL Cell-Mediated MDSC Induction

the IKZF1-IRF4 Axis Regulates Macrophage Polarization and Macrophage-Mediated Anti-Tumor Immunity

Indirect Presentation of Y-Chromosome Antigen Dby Is Regulated By Hsc70 and Mediated through CD63 Positive Exosomes

Lenalidomide Enhances MOR202 Dependent Macrophage-Mediated Effector Functions Via the Vitamin D Pathway

Vitamin D-Dependent Induction of Cathelicidin in Human Macrophages Results in Cytotoxicity Against High Grade B-Cell Lymphoma

Transdifferentiation of Malignant B-Cells into Macrophages in a Murine Model of Burkitt´s Lymphoma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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