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Journal Articles

High Surface IgM Levels Associate with Shorter Response Duration and Bypass of the BTK Blockade during Ibrutinib Therapy in CLL Patients

Giorgia Chiodin, David Dutton, MD, Enrica Antonia Martino, MD, Samantha Drennan, PhD, Ian Tracy, PhD, Laura Ondrisova, Isla Henderson, Annalisa D'Avola, PhD, Christina Pitsillidou, Marek Mraz, MD, Peter Johnson, MDFRCP, Andrew Duncombe, MD, Graham Packham, PhD, Andrew J Steele, PhD, Helen Parker, PhD, Silvia Bonfiglio, Lydia Scarfo, MD, Lesley-Ann Sutton, Paolo Ghia, MD PhD, Matthew John Jerome Rose-Zerilli, PhD, Jonathan C Strefford, PhD, Freda K. Stevenson, DPhil, Francesco Forconi, MD DM, PhD FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 1752.
https://doi.org/10.1182/blood-2019-128899
Published: 2019
Journal Articles

Clinical Importance of DNA Methylation Signatures in Chronic Lymphocytic Leukaemia Patients Treated with Chemo-Immunotherapy

Harindra Amarasinghe, PhD, Tomasz K Wojdacz, PhD MSc, Matthew John Jerome Rose-Zerilli, PhD, Alice Beattie, Jade Forster, PhD, Latha Kadalayil, Stuart Blakemore, PhD, Helen Parker, PhD, Marta Larrayoz, PhD, Ruth Clifford, Zadie Davis, Monica Else, Dena Cohen, Andrew J Steele, PhD, Richard Rosenquist, MD PhD, Andrew Collins, Andrew Pettitt, FRCPath, PhD, Peter Hillmen, MBChB, PhD, Pauline Robbe, MSc, Christopher Plass, Anna Schuh, MD PhD, Daniel Catovsky, MD FRCP, David Oscier, MD PhD, Christopher C. Oakes, PhD, Jonathan C Strefford, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 56.
https://doi.org/10.1182/blood.V130.Suppl_1.56.56
Published: 2017
Journal Articles

The Contribution of Gene Mutations to Long-Term Clinical Outcomes: Data from the Randomised UK LRF CLL4 Trial

Stuart Blakemore, PhD, Ruth Clifford, Pavlos Antoniou, Helen Parker, PhD, Pauline Robbe, MSc, Marta Larrayoz, PhD, Zadie Davis, Latha Kadalyayil, Andrew Collins, Jade Forster, PhD, Monica Else, Andrew J Steele, PhD, Jacqueline Chan, PhD, Graham Speight, PhD, Mark Cragg, PhD, Matthew John Jerome Rose-Zerilli, PhD, Daniel Catovsky, MD FRCP, David Oscier, MD PhD, Anna Schuh, MD PhD, Jonathan C Strefford, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 259.
https://doi.org/10.1182/blood.V130.Suppl_1.259.259
Published: 2017
Journal Articles

Deep-Sequencing Reveals the Molecular Landscape of Splenic Marginal Zone Lymphoma: Biological and Clinical Implications

Matthew JJ Rose-Zerilli, PhD, Marina Parry, Viktor Ljungstrom, Jane Gibson, Jun Wang, Renata Walewska, Helen Parker, PhD, Anton Parker, Zadie Davis, Anne Catherine Gardiner, Neil McIver-Brown, Christina H. Kalpadakis, MD, Aliki Xochelli, Achilles Anagnostopoulos, Claudia Fazi, PhD, David Gonzalez de Castro, PhD, Claire Dearden, MD, Guy Pratt, Richard Rosenquist, MD PhD, Margaret Ashton-Keys, Francesco Forconi, Andrew Collins, PhD, Paolo Ghia, MD PhD, Estella Matutes, MD PhD, Gerassimos A Pangalis, Kostas Stamatopoulos, David G Oscier, MD, Jonathan C Strefford, PhD
Journal: Blood
Blood (2014) 124 (21): 76.
https://doi.org/10.1182/blood.V124.21.76.76
Published: 2014
Journal Articles

Tracking Subclonal Mutations in IGHV-Mutated CLL with Progressive Disease

Matthew JJ Rose-Zerilli, PhD, Gibson Jane, PhD, Jun Wang, PhD, William J Tapper, PhD, Helen Parker, PhD, Anton Parker, Zadie Davis, Anne Catherine Gardiner, Jade Forster, Andrew J Steele, PhD, Renata Walewska, Helen McCarthy, Andrew Collins, PhD, David G Oscier, MD, Jonathan C Strefford, PhD
Journal: Blood
Blood (2014) 124 (21): 1962.
https://doi.org/10.1182/blood.V124.21.1962.1962
Published: 2014
Journal Articles

Mutations In XPO1, POT1, BIRC3 and FBXW7 collectively Predict Poor Outcome At Diagnosis In CLL and MBL Independent From The SF3B1 and NOTCH1 Status

Nils Winkelmann, MD, Mathew J Rose-Zerilli, PhD, Jade Forster, Mathew Parry, PhD, Anton Parker, BSc, Anne Gardiner, Zadie Davies, BSC, Andrew J Steele, PhD, Helen Parker, PhD, Andrew Collins, PhD, Nick C.P. Cross, PhD, David Oscier, MD, Jonathan C Strefford
Journal: Blood
Blood (2013) 122 (21): 4138.
https://doi.org/10.1182/blood.V122.21.4138.4138
Published: 2013
Journal Articles

The Correlation Between Deletion Architecture, ATM Mutational Status and BIRC3 Disruption in 11q-Deleted CLL

Matthew JJ Rose-Zerilli, PhD, Jade Forster, Helen Parker, PhD, Anton Parker, Ana E Rodríguez, Tracy Chaplin, Anne Gardiner, Andrew Collins, PhD, Bryan D Young, PhD, Tatjana Stankovic, MD., PhD, David Oscier, MD, Jonathan C. Strefford, BSc, PhD
Journal: Blood
Blood (2012) 120 (21): 658.
https://doi.org/10.1182/blood.V120.21.658.658
Published: 2012
Journal Articles

Deletion Size Influences Clinical Outcome In Patients with Chronic Lymphocytic Leukemia; 13q Deletion Anatomy, Cooperating Lesions and Cancer Pathogenesis

Helen Parker, PhD, Matthew JJ Rose-Zerilli, PhD, Anton Parker, BSc, Tracy Chaplin, Anne Catherine Gardiner, BSc, Mike Griffiths, Andrew Collins, PhD, Bryan D Young, BSc, PhD, David Graham Oscier, Jonathan C. Strefford, BSc, PhD
Journal: Blood
Blood (2010) 116 (21): 757.
https://doi.org/10.1182/blood.V116.21.757.757
Published: 2010
Journal Articles

Sequential SNP6.0 Microarray Analysis In Rai Stage 0 CLL Patients with Either Stable or Progressive Identifies Genomic Evolution In Both Cohorts

Matthew JJ Rose-Zerilli, PhD, Miqdad Rajibali, BSc, Helen Parker, PhD, Anton Parker, BSc, Anne Catherine Gardiner, BSc, Zadie Davis, PhD, Sarah Mold, BSc, Sharron Glide, BSc, Tracy Chaplin, Bryan D Young, BSc, PhD, David Graham Oscier, Jonathan C. Strefford, BSc, PhD
Journal: Blood
Blood (2010) 116 (21): 1696.
https://doi.org/10.1182/blood.V116.21.1696.1696
Published: 2010
Journal Articles

13q Deletion Size Predicts Disease Progression and Response to Treatment in Patients with Chronic Lymphocytic Leukaemia.

Jonathan C Strefford, PhD, Helen Parker, PhD, Anton Parker, BSc, Hazel Robinson, PhD, Tracy Chaplin, MSc, Xiao-He Chen, PhD, David Bunyan, PhD, Anne Gardiner, BSc, Bryan D Young, PhD, David Graham Oscier, MD
Journal: Blood
Blood (2009) 114 (22): 671.
https://doi.org/10.1182/blood.V114.22.671.671
Published: 2009
Journal Articles

Variable Breakpoints Target PAX5 in Patients with Dicentric Chromosomes: A Model for the Basis of Unbalanced Translocations in Cancer

Jonathan C Strefford, PhD, Qian An, PhD, Sarah L Wright, BSc, Zoe J Konn, BSc, Elizabeth Matherson, PhD, Lynne Minto, PhD, Anthony V Moorman, PhD, Helen Parker, PhD, Andrew Hall, PhD, Julie Irving, PhD, Christine J Harrison, PhD
Journal: Blood
Blood (2008) 112 (11): 790.
https://doi.org/10.1182/blood.V112.11.790.790
Published: 2008