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Journal Articles

Clinical Outcomes in Patients with Waldenström Macroglobulinemia (WM) Receiving Ibrutinib on the Phase 3 ASPEN Study ≥1 Year After Transitioning to Zanubrutinib

Ramon Garcia-Sanz, Roger Owen, Wojciech Jurczak, Meletios A. Dimopoulos, Helen McCarthy, Gavin Cull, Stephen Opat, Jorge J. Castillo, Marie José Kersten, Björn E. Wahlin, Sebastian Grosicki, Radha Prathikanti, Tian Tian, Heather Allewelt, Aileen Cleary Cohen, Constantine S. Tam
Journal: Blood
Blood (2023) 142 (Supplement 1): 3043.
https://doi.org/10.1182/blood-2023-174294
Published: 2023
Journal Articles

Pembrowm: Results of a Multi-Centre Phase II Trial Investigating the Safety and Efficacy of Rituximab and Pembrolizumab in Relapsed/Refractory Waldenström's Macroglobulinaemia

Jaimal Kothari, Toby A. Eyre, Ali Rismani, Helen McCarthy, Angela Collins, David John Lewis, Suzanne O Arulogun, William Wilson, Laura Clifton-Hadley, Darren Edwards, Kushani Ediriwickrema, Rebecca Auer, Guy Pratt, Ruth M. de Tute, Roger G Owen, Shirley D'Sa
Journal: Blood
Blood (2022) 140 (Supplement 1): 3624–3626.
https://doi.org/10.1182/blood-2022-167158
Published: 2022
Journal Articles

Ethnic Disparities in Waldenström's Macroglobulinaemia in the United Kingdom - Analysis from the Wmuk Rory Morrison Registry

Aisha S Patel, Jahanzaib Khwaja, Helen McCarthy, Guy Pratt, Jaimal Kothari, Jindriska Lindsay, Roger G Owen, Josephine Crowe, Dima El-Sharkawi, Nilima Parry-Jones, Kirsty Cuthill, Maria Atta, Kim Linton, Agapi Parcharidou, Charalampia Kyriakou, Deborah Turner, Jeffery Smith, Simona Gatto, Nicola Crosbie, Suzanne O Arulogun, Shirley D'Sa
Journal: Blood
Blood (2021) 138 (Supplement 1): 1977.
https://doi.org/10.1182/blood-2021-153590
Published: 2021
Journal Articles

Intrathecal (IT) Chemotherapy for Central Nervous System (CNS) Prophylaxis in Diffuse Large B-Cell Lymphoma (DLBCL): A Single Centre Retrospective Observational Study

Luke Attwell, Benjamin Gray, Rachel Hall, Sally Killick, MD, Helen McCarthy, PhD FRCPath, Renata Walewska, Joseph M. Chacko, MDMBBS,BSc,FRCP,FRCPath
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–19.
https://doi.org/10.1182/blood-2020-140797
Published: 2020
Journal Articles

Neuropathy with IgM Gammopathy: Incidence, Characteristics and Management, a Rory Morrison W.M.U.K Registry Analysis

Oliver Tomkins, BMBS,MRCP, Jindriska Lindsay, FRCPath, Stephen Keddie, MRCP, Aisling Carr, PhDFRCP, Helen McCarthy, PhD FRCPath, Dima El-Sharkawi, MBBS, FRCPath, PhD, Charalampia Kyriakou, MD PhD, Kirsty Cuthill, FRCPath,MBBS,MRCP,PhD, Guy Pratt, FRCPath, Ali Rismani, FRCPath, Michael P Lunn, Shirley D'Sa, MD FRCPath
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-136558
Published: 2020
Journal Articles

Bendamustine Plus Rituximab for the Treatment of Waldenström Macroglobulinaemia: Patient Outcomes and Impact of Bendamustine Dosing

Suzanne O Arulogun, MBBS, Duncan Brian, Harshita Goradia, Aaron Cooney, Tobias Menne, MD PhD, Dipti Talaulikar, PhD FRACP, FRCPA, MBBS, Aideen Therese O'Neill, FRCPath, Josephine M.I Vos, Guy Pratt, FRCPath, Deborah Turner, Kirsty Marshall, Kate Manos, MBBS, Claire Anderson, Maria Gavriatopoulou, Charalampia Kyriakou, MD PhD, Monique C. Minnema, Dima El-Sharkawi, MBBS, FRCPath, PhD, Marie José Kersten, MD PhD, RayMun Koo, Helen McCarthy, PhD FRCPath, Mark Bishton, MBChB, MRCP, FRCPath, PhD, George Follows, Ashutosh D. Wechalekar, Shirley D'Sa, MD FRCPath
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-140774
Published: 2020
Journal Articles

Subcutaneous Daratumumab (DARA SC) Plus Standard-of-Care (SoC) Regimens in Multiple Myeloma (MM) across Lines of Therapy in the Phase 2 Pleiades Study: Initial Results of the Dara SC Plus Carfilzomib/Dexamethasone (D-Kd) Cohort, and Updated Results for the Dara SC Plus Bortezomib/Melphalan/Prednisone (D-VMP) and Dara SC Plus Lenalidomide/Dexamethasone (D-Rd) Cohorts

Philippe Moreau, MD, Ajai Chari, Mathias Haenel, MD, Albert Oriol, Paula Rodriguez-Otero, MD PhD, Helen McCarthy, PhD FRCPath, Kenshi Suzuki, MD PhD, Vania T. M. Hungria, MD PhD, Anna Sureda Balari, MD PhD, Lauriane Clement-Filliatre, MD, Cyrille Hulin, MD, Hila Magen, MD, Shinsuke Iida, MD PhD, Vladimir Maisnar, MD, Lionel Karlin, MD, Luděk Pour, MD, Cyrille Touzeau, Shiyi Yang, Michele Kosh, Maria Delioukina, Christoph Heuck, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–30.
https://doi.org/10.1182/blood-2020-134935
Published: 2020
Journal Articles

A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenström macroglobulinemia: the ASPEN study

Clinical Trials & Observations
Constantine S. Tam, Stephen Opat, Shirley D'Sa, Wojciech Jurczak, Hui-Peng Lee, Gavin Cull, Roger G. Owen, Paula Marlton, Björn E. Wahlin, Ramón Garcia Sanz, Helen McCarthy, Stephen Mulligan, Alessandra Tedeschi, Jorge J. Castillo, Jaroslaw Czyz, Carlos Fernández de Larrea, David Belada, Edward Libby, Jeffrey V. Matous, Marina Motta, Tanya Siddiqi, Monica Tani, Marek Trneny, Monique C. Minnema, Christian Buske, Veronique Leblond, Judith Trotman, Wai Y. Chan, Jingjing Schneider, Sunhee Ro, Aileen Cohen, Jane Huang, Meletios Dimopoulos
Journal: Blood
Blood (2020) 136 (18): 2038–2050.
https://doi.org/10.1182/blood.2020006844
Published: 2020
Includes: Supplemental data
Journal Articles

An Analysis from the WM UK Rory Morrison Registry - How Does Waldenström's Macroglobulinemia Affect Younger Patients?

Oliver Tomkins, BMBS, MRCP, Joshua Bomsztyk, Helen McCarthy, MBBS, PhD, Jaimal Kothari, Dima El-Sharkawi, Charalampia Kyriakou, Guy Pratt, Ali Rismani, MBBS, Shirley D'Sa
Journal: Blood
Blood (2019) 134 (Supplement_1): 1543.
https://doi.org/10.1182/blood-2019-123693
Published: 2019
Journal Articles

An Analysis from the WM UK Rory Morrison Registry: Waldenström's Macroglobulinaemia Patient Demographics, Disease Characteristics and Evolving Treatment Choices

Oliver Tomkins, BMBS, MRCP, Joshua Bomsztyk, Helen McCarthy, MBBS, PhD, Jaimal Kothari, Dima El-Sharkawi, Charalampia Kyriakou, Guy Pratt, Ali Rismani, MBBS, Shirley D'Sa
Journal: Blood
Blood (2019) 134 (Supplement_1): 4016.
https://doi.org/10.1182/blood-2019-129212
Published: 2019
Journal Articles

Ibrutinib at First Relapse for Mantle Cell Lymphoma: A United Kingdom Real World Analysis of Outcomes in 169 Patients

Rory McCulloch, FRCPath, MRCP, MBBS, Simon Rule, Toby A. Eyre, Harshita Goradia, Simon Bolam, MD, Thomas Creasey, MBBS, David Tucker, MD, Michelle Furtado, Oliver Miles, Samuel Harrison, Amir Shenouda, Andrew Robinson, Matthew Wilson, MD BSc, MRCP, Annabel McMillan, Nimish Shah, Graham McIlroy, MD, David Dutton, MD, Adam Bond, Luke Attwell, Alexander Langridge, Helen Parry, MB ChB, MRCP, PhD, John Willan, Gavin Campbell, FRCP,FRCPath, Deborah Turner, David Lewis, PhD FRCPath, BSc, Helen McCarthy, MBBS, PhD, Jonathan Lambert, Pamela McKay, MD, Neil Phillips, Shankara Paneesha, MD, Wendy Osborne, MD, Mark Bishton, Nicola Crosbie
Journal: Blood
Blood (2019) 134 (Supplement_1): 3993.
https://doi.org/10.1182/blood-2019-125947
Published: 2019
Journal Articles

Subcutaneous Daratumumab Plus Standard Treatment Regimens in Patients with Multiple Myeloma across Lines of Therapy: Pleiades Study Update

Ajai Chari, MD, Jesús San-Miguel, Helen McCarthy, MBBS, PhD, Kenshi Suzuki, MD PhD, Vania T.M. Hungria, MD PhD, Anna Sureda, MD PhD, Aurore Perrot, MD PhD, Cyrille Hulin, MD, Hila Magen, MD, Shinsuke Iida, MD PhD, Vladimir Maisnar, MD PhD MBA, Lionel Karlin, MD, Ludek Pour, MD, Dolly A. Parasrampuria, PhD, Tara Masterson, Michele Kosh, RN, BSN, Shiyi Yang, Maria L. Delioukina, MD, Ming Qi, MD PhD, Robin Carson, MD BA, Cyrille Touzeau, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3152.
https://doi.org/10.1182/blood-2019-123560
Published: 2019
Journal Articles

Prolonged Improvement in Patient-Reported Outcomes (PROs) and Well-being in Older Patients With Treatment-Naïve (TN) Chronic Lymphocytic Leukemia Treated With Ibrutinib (Ibr): 3-Year Follow-up of the RESONATE-2 Study

Alessandra Tedeschi, MD, Carolyn Jane Owen, MD FRCPC, Tadeusz Robak, MD PhD, Paul M. Barr, MD, Osnat Bairey, MD, Peter Hillmen, MBChB, PhD, Steven Coutre, MD, Stephen Devereux, FRCP, FRCPath, PhD, Sebastian Grosicki, MD PhD, Helen McCarthy, MBBS, PhD, Jianyong Li, MD, David Simpson, MBChB, Tanya Siddiqi, MD, Giri Iyer, MBA, Indu D. Lal, MD, Jeremiah Trudeau, PhD, Sandra Dai, PhD, James P. Dean, MD PhD, Danelle F. James, MD MAS, Jan A. Burger, MD PhD, Paolo Ghia, MD PhD, Thomas J. Kipps, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1746.
https://doi.org/10.1182/blood.V130.Suppl_1.1746.1746
Published: 2017
Journal Articles

Single-Agent Ibrutinib Vs Chemoimmunotherapy Regimens for Treatment-Naïve Patients with Chronic Lymphocytic Leukemia (CLL): A Cross-Trial Comparison

Tadeusz Robak, MD PhD, Jan A. Burger, MD PhD, Alessandra Tedeschi, MD, Paul M. Barr, MD, Carolyn Jane Owen, MD FRCPC, Osnat Bairey, MD, Peter Hillmen, MBChB, PhD, David Simpson, MBChB, Sebastian Grosicki, MD PhD, Stephen Devereux, FRCP, FRCPath, PhD, Helen McCarthy, MBBS, PhD, Steven Coutre, MD, Hang Quach, MBBS, MD, Gianluca Gaidano, MD PhD, Zvenyslava Maslyak, MD, Don A Stevens, MD, Carol Moreno, MD, Devinder Gill, MD, Ian W. Flinn, MD PhD, John Gribben, MD DSc, Ahmad Mokatrin, PhD, Mei Cheng, PhD, Lori Styles, MD, Danelle F. James, MD MAS, Thomas J. Kipps, MD, Paolo Ghia, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1750.
https://doi.org/10.1182/blood.V130.Suppl_1.1750.1750
Published: 2017
Journal Articles

Updated Efficacy and Safety from the Phase 3 Resonate-2 Study: Ibrutinib As First-Line Treatment Option in Patients 65 Years and Older with Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia

Paul Barr, MD, Tadeusz Robak, MD PhD, Carolyn J Owen, Alessandra Tedeschi, Osnat Bairey, MD, Nancy L Bartlett, MD, Jan Burger, MD PhD, Peter Hillmen, Steven Coutre, MD, Stephen Devereux, PhD FRCP, FRCPath, Sebastian Grosicki, MD PhD, Helen McCarthy, MBBS, PhD, Jianyong Li, MD, David Simpson, Fritz Offner, MD, Carol Moreno, MD, Cathy Zhou, MS, Lori Styles, MD, Danelle F. James, MD MAS, Thomas J. Kipps, MD, PhD, Paolo Ghia, MD PhD
Journal: Blood
Blood (2016) 128 (22): 234.
https://doi.org/10.1182/blood.V128.22.234.234
Published: 2016
Journal Articles

Results from the International, Randomized Phase 3 Study of Ibrutinib Versus Chlorambucil in Patients 65 Years and Older with Treatment-Naïve CLL/SLL (RESONATE-2 TM )

Alessandra Tedeschi, MD, Paul M. Barr, MD, Tadeusz Robak, MD PhD, Carolyn Owen, MD, Paolo Ghia, MD PhD, Osnat Bairey, MD, Peter Hillmen, MB, ChB, PhD, Nancy L Bartlett, MD, Jianyong Li, MD, David Simpson, MBBS, Sebastian Grosicki, MD PhD, Stephen Devereux, FRCP, FRCPath, PhD, Helen McCarthy, FRCP, FRCPath, PhD, Steven Coutre, MD, Hang Quach, MD, Gianluca Gaidano, MD PhD, Zvenyslava Maslyak, MD, Don A. Stevens, MD, Ann Janssens, MD, Fritz Offner, MD PhD, Jiří Mayer, MD, Michael O'Dwyer, MD, Andrzej Hellmann, MD PhD, Anna Schuh, MD PhD, Tanya Siddiqi, MD, Aaron Polliack, MD, Constantine S. Tam, MBBS, Michael Keating, MBBS, Deepali Suri, MS, Cathy Zhou, MS, Fong Clow, ScD, Lori Styles, MD, Danelle F. James, MD MAS, Thomas J. Kipps, MD, PhD, Jan A. Burger, MD PhD
Journal: Blood
Blood (2015) 126 (23): 495.
https://doi.org/10.1182/blood.V126.23.495.495
Published: 2015
Journal Articles

Tracking Subclonal Mutations in IGHV-Mutated CLL with Progressive Disease

Matthew JJ Rose-Zerilli, PhD, Gibson Jane, PhD, Jun Wang, PhD, William J Tapper, PhD, Helen Parker, PhD, Anton Parker, Zadie Davis, Anne Catherine Gardiner, Jade Forster, Andrew J Steele, PhD, Renata Walewska, Helen McCarthy, Andrew Collins, PhD, David G Oscier, MD, Jonathan C Strefford, PhD
Journal: Blood
Blood (2014) 124 (21): 1962.
https://doi.org/10.1182/blood.V124.21.1962.1962
Published: 2014
Journal Articles

Are Outcomes Worse For Patients With Polycythemia Vera compared to Polycythemia Of Unknown Cause? – a Retrospective Analysis Of Single Institution Patient Cohorts

Joseph Chacko, Sara Boyce, Sally Killick, Hall Rachel, Helen McCarthy, Walewska Renata, Louise Wallis
Journal: Blood
Blood (2013) 122 (21): 4079.
https://doi.org/10.1182/blood.V122.21.4079.4079
Published: 2013
Journal Articles

NCRN CLL207 Study of Alemtuzumab Consolidation In CLL: Final Response Assessment and Early Follow-up (on Behalf of the NCRI CLL Trials Sub-Group)

Abraham M Varghese, Dena Cohen, Christopher F.E. Pocock, MD, PhD, Andy Rawstron, PhD, Walter M Gregory, Alex Smith, Emma Skinner, BSc, Anne Critchley, MB, BS, Donald Milligan, MD, FRCP, FRCPath, Claire E. Dearden, MD, Helen McCarthy, Chris Fegan, George A Follows, Peter Hillmen, MBChB, FRCP, FRCPath, PhD
Journal: Blood
Blood (2010) 116 (21): 60.
https://doi.org/10.1182/blood.V116.21.60.60
Published: 2010
Journal Articles

High expression of activation-induced cytidine deaminase (AID) and splice variants is a distinctive feature of poor-prognosis chronic lymphocytic leukemia

Helen McCarthy, William G. Wierda, Lynn L. Barron, Candy C. Cromwell, Jing Wang, Kevin R. Coombes, Roberto Rangel, Kojo S. J. Elenitoba-Johnson, Michael J. Keating, Lynne V. Abruzzo
Journal: Blood
Blood (2003) 101 (12): 4903–4908.
https://doi.org/10.1182/blood-2002-09-2906
Published: 2003