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Journal Articles

Drug Response Profiling Informs Personalized Bridging to Cell Therapy for Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

Fabio D. Steffen, Andrej Lissat, Julia Alten, Cornelia Eckert, Nicole Bodmer, Bodil E. Thorhauge Als-Nielsen, Adriana Balduzzi, Barbara Buldini, Sarah Elitzur, Andras Kriston, Gergely Nyiri, Imre Västrik, Ferenc Kovacs, Francesco Ceppi, Lucie Sramkova, Larissa Schori, Arianna Arpagaus, Silvia Gutnik, Andishe Attarbaschi, Birgitte Klug Albertsen, Jeanette Greiner, Marc Ansari, Judith M. Boer, Elad Jacoby, Martin Stanulla, Uri Ilan, Peter M. Hoogerbrugge, Tim Lammens, Barbara De Moerloose, Petter Svenberg, Nicolas von der Weid, David O'Connor, Hélène Cavé, Franco Locatelli, Martin Schrappe, André Baruchel, Andreas Kulozik, Kjeld Schmiegelow, Gunnar Cario, Arend von Stackelberg, Peter Horvath, Beat Bornhauser, Jean-Pierre Bourquin
Journal: Blood
Blood (2023) 142 (Supplement 1): 4350.
https://doi.org/10.1182/blood-2023-179306
Published: 2023
Journal Articles

ALL-REZ BFM 2002 Is Associated with Improved Outcome as Compared to ALL-R3 Strategy in Children with Standard Risk Isolated CNS Relapse of Acute Lymphoblastic Leukemia, while Maintaining Comparable Efficacy in Patients with Bone Marrow Relapse. Results of the Multi-National, Multi-Center Trial IntReALL SR 2010

Arend von Stackelberg, Jean-Pierre Bourquin, Martin Zimmermann, Tamas Revesz, Andishe Attarbaschi, Alina Ferster, Lucie Sramkova, Thomas Leth Frandsen, Päivi Maria Lähteenmäki, Ronit Elhasid, Hidemi Toyoda, Peter M. Hoogerbrugge, Inga M. Johannsdottir, Ximo Duarte, Denise Bonney, Vaskar Saha, Ingo G. Steffen, Andrej Lissat, Christiane Chen-Santel, Cornelia Eckert, Andre Baruchel, Arnaud Petit, Hélène Cavé, Carmelo Rizzari, Giovanni Cazzaniga, Luciana Vinti, Pierre Rohrlich, Franco Locatelli
Journal: Blood
Blood (2022) 140 (Supplement 1): 3247–3249.
https://doi.org/10.1182/blood-2022-166234
Published: 2022
Journal Articles

Implication of ICOSLG on Relapse in Infant T(4;11) Acute Lymphoblastic Leukemia

Marius Külp, Anna Lena Siemund, Claus Meyer, Patrizia Larghero, Alissa Dietz, Julia Alten, Gunnar Cario, Aurélie Caye-Eude, Hélène Cavé, Michela Bardini, Paola De Lorenzo, Giovanni Cazzaniga, Laura Diehl, Halvard Bonig, Rolf Marschalek
Journal: Blood
Blood (2021) 138 (Supplement 1): 3481.
https://doi.org/10.1182/blood-2021-146181
Published: 2021
Journal Articles

Targeted Next Generation Sequencing Reveals a Third Breakpoint Cluster Region and New Partner Genes in the KMT2A Recombinome

Claus Meyer, Patrizia Larghero, Bruno Lopes, Aurélie Caye-Eude, Hélène Cavé, Marius Külp, Matthew James Smith, Rosemary Sutton, Nicola Venn, Karin Nebral, Susanne Kubetzko, Beat Schaefer, Grazia Fazio, Giovanni Cazzaniga, Mariana Emerenciano, Rolf Marschalek
Journal: Blood
Blood (2021) 138 (Supplement 1): 3327.
https://doi.org/10.1182/blood-2021-146172
Published: 2021
Journal Articles

NUTM1 -Rearranged Infant and Pediatric B Cell Precursor Acute Lymphoblastic Leukemia: A Good Prognostic Subtype Identified in a Collaborative International Study

Judith M. Boer, PhD, Maria Grazia Valsecchi, PhD, Femke M. Hormann, MSc, Zeljko Antic, MD, Marketa Zaliova, MD PhD, Claire Schwab, PhD, Giovanni Cazzaniga, PhD, Chloé Arfeuille, MD, Hélène Cavé, PharmD, PhD, Andishe Attarbaschi, MD, Sabine Strehl, PhD, Gabriele Escherich, MD, Toshihiko Imamura, MD PhD, Kentaro Ohki, MD PhD, Tanja A. Gruber, MD PhD, Rosemary Sutton, BSc MSc PhD, Agata Pastorczak, Tim Lammens, PhD, Frederic Lambert, MD, Chi Kong Li, MD, Enrique Carrillo de Santa Pau, PhD, Steve Hoffmann, MD PhD, Anja Möricke, MD, Christine J. Harrison, PhD FRCPath, Monique L. Den Boer, PhD, Paola De Lorenzo, Ronald W. Stam, PhD, Anke K. Bergmann, MD PhD, Rob Pieters, MDPhDMSc
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-139376
Published: 2020
Journal Articles

How Many Patients Have Congenital Neutropenia? a Population-Based Estimation from the Nationwide French Severe Chronic Neutropenia Registry

Jean Donadieu, MDPhD, Blandine Beaupain, MsC, Hélène Lapillonne, MD PhD, Odile Fenneteau, PharmD, Flore Sicre de Fontbrune, Yves Bertrand, MD, Nathalie Aladjidi, MD, Vincent Barlogis, MD, PhD, Wadih Abou Chahla, MD, Thierry Lamy, PhD MD, Aline Moignet Autrel, MD, Claire Fieschi, MD PhD, Thierry Leblanc, MD, Despina Moshous, MD PhD, Jean Soulier, MDPhD, Sarah cohen Beaussant, Francois Delhommeau, MD PhD, Helene Cavé, PharmD, PhD, Catherine Paillard, MD PhD, Elodie Gouache, MD, Fares bou Mitri, Damien Bonnet, Laurence Olivier Faivre, Philippe Labrune, MD PhD, Marlène Pasquet, MD, PhD, Virginie Gandemer, MD PhD, Nizar Mahlaoui, MD, Karl Balabanian, Francoise Bachelerie, PhD, Christine Bellanne-Chantelot, PhD PharmD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-135912
Published: 2020
Journal Articles

JMML Fetal Identity Results Either from Retention of a Physiologic Signature or Aberrant Activation of Master Oncofetal Regulators

Marion Strullu, MD, Aurélie Caye-Eude, PharmD, PhD, Loïc Maillard, PhD, Chloé Arfeuille, MD, Elodie Lainey, PharmD, PhD, Florian Piques, MD, Odile Fenneteau, PharmD, Bruno Cassinat, PharmD, PhD, Fabien Guimiot, PhD, Jean-Hugues Dalle, MD PhD, André Baruchel, Christine Chomienne, MD PhD, Dominique Bonnet, PhD, Michele Souyri, PhD, Hélène Cavé, PharmD, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4–5.
https://doi.org/10.1182/blood-2020-136367
Published: 2020
Journal Articles

IKZF1 deletions in pediatric acute lymphoblastic leukemia: still a poor prognostic marker?

Clinical Trials & Observations
Martin Stanulla, Hélène Cavé, Anthony V. Moorman
Journal: Blood
Blood (2020) 135 (4): 252–260.
https://doi.org/10.1182/blood.2019000813
Published: 2020
Journal Articles

Acute Lymphoblastic Leukemia with Zinc-Finger Protein 384 (ZNF384)-Related Rearrangements: A Retrospective Analysis from the Ponte Di Legno Childhood ALL Working Group

Shinsuke Hirabayashi, Ellie Butler, Kentaro Ohki, MD PhD, Nobutaka Kiyokawa, MD PhD, Anke K. Bergmann, Judith M. Boer, PhD, Hélène Cavé, PharmD, PhD, Giovanni Cazzaniga, Allen Eng Juh Yeoh, Toshihiko Imamura, MD PhD, Hiroto Inaba, MD, Mignon L. Loh, MD, Ulrika Norén-Nyström, MD PhD, Agata Pastorczak, Lee-Yung Shih, MD, Marketa Zaliova, MD PhD, Oskar A Haas, Christine J. Harrison, PhD FRCPath, Anthony V. Moorman, Atsushi Manabe, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 652.
https://doi.org/10.1182/blood-2019-123236
Published: 2019
Journal Articles

Mcph1 , Mutated in Primary Microcephaly, Is Required to Complete Terminal Erythroid Differentiation

Yoann Vial, PharmD, Jeannette Nardelli, PhD, Justine Rousselot, Emilie Lepeu, Michele Souyri, PhD, Sandrine Passemard, MD PhD, Helene Cave, PharmD, PhD, Severine Drunat, PharmD, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1192.
https://doi.org/10.1182/blood-2019-126475
Published: 2019
Journal Articles

Safety and Efficacy of Tisagenlecleucel (CTL019) in B-Cell Acute Lymphoblastic Leukemia in Children, Adolescents and Young Adults: The French Experience

Marie-Emilie Dourthe, Florence Rabian, MD, Karima Yakouben, MD, Aurélie Cabannes, MD, Florian Chevillon, MD, Delphine Chaillou, Nathalie Dhedin, MD, Emmanuelle Lesprit, MD, Jerome Naudin, MD, Julie Roupret-Serzec, PharmD, Nathalie Parquet, MD, Anne Brignier, MD, Valérie Guérin, MD, Elodie Lainey, PhD, Aurélie Caye-Eude, PharmD, Helene Cavé, PharmD, PhD, Emmanuelle Clappier, PhD PharmD, Stéphanie Mathis, PharmD, Sophie Caillat-Zucman, MD PhD, Elie Azoulay, MD PhD, Jean-Hugues Dalle, MD PhD, Isabelle Madelaine, PharmD, Jerome Larghero, PharmD, PhD, Nicolas Boissel, MD PhD, André Baruchel, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3876.
https://doi.org/10.1182/blood-2019-131123
Published: 2019
Journal Articles

Long Non-Coding RNAs As Novel Therapeutic Targets in Juvenile Myelomonocytic Leukemia: Proof of Concept Study

Mattias Hofmans, MD, Barbara Depreter, PhD PharmD, Tim Lammens, PhD, Helene Cave, PharmD, PhD, Christian Flotho, MD PhD, Henrik Hasle, Valerie de Haas, MD PhD, Charlotte M. Niemeyer, MD, Jan Stary, Prof., MD PhD, Pieter Van Vlierberghe, PhD, Jan Philippé, MD PhD, Barbara De Moerloose, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1701.
https://doi.org/10.1182/blood-2019-123715
Published: 2019
Journal Articles

Efficacy of tyrosine kinase inhibitors in Ph-like acute lymphoblastic leukemia harboring ABL-class rearrangements

Ilaria Tanasi, Ibrahima Ba, Nicolas Sirvent, Thorsten Braun, Wendy Cuccuini, Paola Ballerini, Nicolas Duployez, Aline Tanguy-Schmidt, Jérôme Tamburini, Sébastien Maury, Eric Doré, Chantal Himberlin, Cédric Duclos, Patrice Chevallier, Philippe Rousselot, Massimiliano Bonifacio, Hélène Cavé, André Baruchel, Hervé Dombret, Jean Soulier, Judith Landman-Parker, Nicolas Boissel, Emmanuelle Clappier
Journal: Blood
Blood (2019) 134 (16): 1351–1355.
https://doi.org/10.1182/blood.2019001244
Published: 2019
Includes: Supplemental data
Journal Articles

MLL-USP2 : An Underestimated New Entity of MLL -Rearranged Leukemia Identified By NGS Analysis

Claus Meyer, PhD, Bruno Lopes, PhD, Aurélie Caye-Eude, PharmD, Hélène Cavé, PharmD, PhD, Chloé Arfeuille, PhD, Rosemary Sutton, PhD, Nicola Venn, BSc, Patrizia Larghero, PhD, Seung Hwan Oh, MD, Grigory Tsaur, MD PhD, Marketa Zaliova, Jan Zuna, Vesa Juvonen, PhD, Renate Panzer-Grümayer, MD, Grazia Fazio, PhD, Giovanni Cazzaniga, PhD, Mariana Emerenciano, PhD, Rolf Marschalek, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3920.
https://doi.org/10.1182/blood-2018-99-112594
Published: 2018
Journal Articles

A Treatment Protocol with Imatinib and Intensive Chemotherapy for Pediatric Philadelphia Positive Acute Lymphoblastic Leukemia Patients: A Single-Arm, Intergroup Study (EsPhALL 2010-2014)

Andrea Biondi, MD, Virginie Gandemer, MDPhD, Myriam Campbell, MD, Anders Castor, MD PhD, Rob Pieters, MD PhD, Paola De Lorenzo, PhD, Veronica Leoni, MD, Jan Stary, Gabriele Escherich, MD, Chi Kong Li, MD, Giovanni Cazzaniga, PhD, Helene Cave, PharmD, PhD, Silja Roettgers, PhD, Valentino Conter, MD, Vaskar Saha, MD PhD, Martin Schrappe, MD PhD, Maria Grazia Valsecchi, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 97.
https://doi.org/10.1182/blood.V130.Suppl_1.97.97
Published: 2017
Journal Articles

B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) with t(5;14)(q31;q32)/ IL3-IGH Rearrangement and Eosinophilia: A Peculiar IGH BCP-ALL

Benjamin Fournier, Estelle Balducci, PharmD, Nicolas Duployez, PharmD, PhD, Emmanuelle Clappier, PharmD,PhD, Wendy Cuccuini, Elodie Bottolier-Colomb, MD, Denis Caillot, MD, Helene Cave, PharmD, PhD, Aurélie Caye-Eude, PharmD, Eric Delabesse, MD PhD, Coralie Derrieux, PharmD, Nathalie Dhedin, MD, Florent Dumezy, MD, Pascaline Etancelin, PharmD, Odile Fenneteau, MD, Jamilé Frayfer, MD, Antoine Gourmel, MD, Marie Loosveld, MD PhD, Gerard Michel, MD, Nathalie Nadal, Claire-Helene Oudin, Dominique Penther, MD, Isabelle Tigaud, MD, Nathalie Grardel, MD, Marine Lafage, MD, Andre Baruchel, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2572.
https://doi.org/10.1182/blood.V130.Suppl_1.2572.2572
Published: 2017
Journal Articles

Immunophenotypic Profiling of Childhood B-Cell Precursor Acute Lymphoblastic Helps Identifying Genetic Subtypes, Including Recently Identified Ones

Elodie Lainey, PharmD/PhD, Aurelie Caye-Eude, PharmD, Lucile Broseus, Emmanuelle Clappier, PharmD, PhD, Wendy Cuccuini, MD PhD, Cristina Leschi, PharmD, Odile Fenneteau, PharmD, Jimmy Mullaert, Amandine Chaye, Ahlene Emam, Benoit Brethon, MD, Thierry Leblanc, MD, Andre Baruchel, MD, Helene Cave, PharmD, PhD
Journal: Blood
Blood (2016) 128 (22): 2910.
https://doi.org/10.1182/blood.V128.22.2910.2910
Published: 2016
Journal Articles

Impact of Age and Treatment Group in Childhood High Hyperdiploid Low Risk B-Cell Acute Lymphoblastic Leukemia (ALL): Results of the CLG-EORTC 58951 Study

Laura Clement, Stefan Suciu, PhD, Isabelle Luquet, MD, Alina Ferster, MD PhD, Karima Yakouben, MD, Anne Uytterbroeck, Catherine Paillard, MD PhD, Nicolas Sirvent, Vitor Costa, Barbara De Moerloose, MD, Francoise Mazingue, Emmanuel Plouvier, MD, Martine Munzer, Maryline Poirée, Odile Minckes, MD, Frédéric Millot, MD, Dominique Plantaz, Caroline Piette, Frank Speleman, Prof, Hélène Cavé, Jutte VanderWerff-tenBossch, Pierre Simon Rohrlich, MDPhD, Yves Bertrand, Yves Benoit, Geneviève Plat
Journal: Blood
Blood (2016) 128 (22): 1743.
https://doi.org/10.1182/blood.V128.22.1743.1743
Published: 2016
Journal Articles

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia

Hetty H. Helsmoortel, Silvia Bresolin, Tim Lammens, Hélène Cavé, Peter Noellke, Aurélie Caye, Farzaneh Ghazavi, Andrica de Vries, Henrik Hasle, Veerle Labarque, Riccardo Masetti, Jan Stary, Marry M. van den Heuvel-Eibrink, Jan Philippé, Nadine Van Roy, Yves Benoit, Frank Speleman, Charlotte Niemeyer, Christian Flotho, Giuseppe Basso, Geertruy te Kronnie, Pieter Van Vlierberghe, Barbara De Moerloose
Journal: Blood
Blood (2016) 127 (9): 1163–1172.
https://doi.org/10.1182/blood-2015-09-667808
Published: 2016
Includes: Supplemental data
Journal Articles

t(12;21)/ ETV6 - RUNX1 Confers a Specific Pattern of In Vivo Sensitivity to Treatments in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL): Results of the Randomized Trials 58881 and 58951 of the EORTC Children Leukemia Group

Caroline Piette, Stefan Suciu, Emmanuelle Clappier, Yves Bertrand, MDPhD, Genevieve Plat, MD, Christophe Chantrain, Vitor Costa, Nicole Dastugue, Alina Ferster, Caroline Gilotay, Sandrine Girard, Nathalie Grardel, Patrick Lutz, Francoise Mazingue, MD, Odile Minckes, Martine Munzer, Emmanuel Plouvier, MD, Nicolas Sirvent, Anne Uyttebroeck, Nadine van Roy, MD, Karima Yakouben, MD, Yves Benoit, Hélène Cavé
Journal: Blood
Blood (2015) 126 (23): 793.
https://doi.org/10.1182/blood.V126.23.793.793
Published: 2015