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Journal Articles

An Enhanced Sensitivity DNA Sequencing Protocol for the Detection in AML of Measurable Residual Disease (MRD) Applicable for All Mutations

Hugh Y. Rienhoff, Jr., MD, Georges Natsoulis, PhD, Amber Jones, MA, Jennifer Peppe, BS, Ru Cao, PhD, Khalid Hanif, PhD, Justin M. Watts, MD

Blood (2018) 132 (Supplement 1): 5279.

https://doi.org/10.1182/blood-2018-99-115505

Published: 2018

Journal Articles

Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB

Anna L. Brown, PhD BSc, Mark Armstrong, MSc, David Lawrence, Paul Wang, Peer Arts, PhD, Nicolas Duployez, PharmD, PhD, Jane Churpek, MD, Kiran Tawana, MD, Erin Degelman, MSc, BSc, Georges Natsoulis, PhD, Monica L. Guzman, PhD, Mrinal M. Patnaik, MD MBBS, Akiko Shimamura, MD PhD, Alan B. Cantor, MD PhD, Tim Ripperger, MD PhD, Brigitte Schlegelberger, MD PhD, Doris Steinemann, PhD, Courtney D. DiNardo, MD MSc, Cristina Mecucci, MD PhD, Elvira DRP Velloso, MD PhD, Fabio PS Santos, MD, Marcela CA Silva, Uma Borate, MD, Shannon K. McWeeney, PhD, Grzegorz Nalepa, MD PhD, Susanne Ragg, MD PhD, Erika Mijin Kwon, PhD, Anupriya Agarwal, PhD, Stephen Langabeer, PhD, Jeffery M. Klco, MD PhD, Jun J. Yang, PhD, Cecily Forsyth, FRACP, FRCPA, MBBS, Sally Mapp, MD PhD, Helen Mar Fan, MD, Lesley Rawlings, PhD, Rachel Susman, Sue Morgan, FRACP, FRCPA, MBBS, Andrew H Wei, MBBS,PhD, Inderjeet Dokal, MD, Tom Vulliamy, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD, Deepak Singhal, MBBS, MD FRACP, FRCPA, Susan Branford, PhD, Elli Papaemmanuil, PhD, Jean Soulier, MDPhD, Stefan Fröhling, MD, Alwin Kramer, MD, Guy Sauvageau, MD PhD, Neil Morgan, Carolyn Owen, Csaba Bödör, PhD, Jude Fitzgibbon, Hugh Y. Rienhoff, Jr., MD, Mineo Kurokawa, MD PhD, Lucy Godley, MD PhD, Claude Preudhomme, Paul P Liu, MD PhD, Nicola Poplawski, MD, Christopher N. Hahn, PhD, Hamish S. Scott, PhD

Blood (2018) 132 (Supplement 1): 5241.

https://doi.org/10.1182/blood-2018-99-118017

Published: 2018

Journal Articles

Pharmacologic LSD1 Inhibition Preserves Human Granulocytic While Expanding Monocytic Progenitors

Karlotta E Kahmann, Stefanie Kesper, Marco Luciani, Michael Möllmann, Hugh Y. Rienhoff, Jr., MD, Ulrich Dührsen, Prof, MD PhD, Joachim R Göthert, MD

Blood (2018) 132 (Supplement 1): 2645.

https://doi.org/10.1182/blood-2018-99-113887

Published: 2018

Journal Articles

LSD1 inhibition exerts its antileukemic effect by recommissioning PU.1- and C/EBPα-dependent enhancers in AML

Monica Cusan, Sheng F. Cai, Helai P. Mohammad, Andrei Krivtsov, Alan Chramiec, Evangelia Loizou, Matthew D. Witkin, Kimberly N. Smitheman, Daniel G. Tenen, Min Ye, Britta Will, Ulrich Steidl, Ryan G. Kruger, Ross L. Levine, Hugh Y. Rienhoff, Jr, Richard P. Koche, Scott A. Armstrong

Blood (2018) 131 (15): 1730–1742.

https://doi.org/10.1182/blood-2017-09-807024

Published: 2018

Includes: Supplemental data

Journal Articles

The Small Molecule Img-98, a Potent and Selective Inhibitor of the Lysine Demethylase Lsd-1, Effectively Augments the Pro-Differentiation Effects of ATRA in a Pre-Clinical Model of AML

Ronan T. Swords, MDPhDFRCPI FRCPath, Aymee Perez, PhD, Ana Rodriguez, Justin M. Watts, MD, Fernando Vargas, MD, Roy Elias, Hugh Y. Rienhoff, Jr., MD, Arthur Zelent, PhD

Blood (2015) 126 (23): 460.

https://doi.org/10.1182/blood.V126.23.460.460

Published: 2015

Journal Articles

R2 and R2* Are Equally Effective In Evaluating Chronic Response To Iron Chelation

John C. Wood, MD, PhD, Pinggao Zhang, PhD, Hugh Y. Rienhoff, Jr., MD, Walid Abi-Saab, MD, Ellis J. Neufeld, MD, PhD

Blood (2013) 122 (21): 3437.

https://doi.org/10.1182/blood.V122.21.3437.3437

Published: 2013

Journal Articles

Liver MRI Is Better Than Biopsy For Assessing Total Body Iron Balance: Validation By Simulation

John C. Wood, MD, PhD, Pinggao Zhang, PhD, Hugh Y. Rienhoff, Jr., MD, Walid Abi-Saab, MD, Ellis J. Neufeld, MD, PhD

Blood (2013) 122 (21): 958.

https://doi.org/10.1182/blood.V122.21.958.958

Published: 2013

Journal Articles

Safety, Tolerability and Dose Response of FBS0701, a Novel Iron Chelator for Treatment of Transfusional Iron Overload: Results of a 24-Week Multicenter, International Phase 2 Study

Ellis J. Neufeld, MD, PhD, Renzo Galanello, MD, Vip Viprakasit, MD; DPhil, Yesim Aydinok, MD, Antonio Piga, MD, Paul Harmatz, MD, Gian Luca Forni, MD, Farrukh T Shah, MBBS, MD, Rachael F. Grace, MD, John B. Porter, MD, Elliott Vichinsky, MD, John C Wood, MD, Ph.D, Jennifer Peppe, Amber Jones, Hugh Y Rienhoff, Jr., MD

Blood (2011) 118 (21): 690.

https://doi.org/10.1182/blood.V118.21.690.690

Published: 2011

Journal Articles

Disparities Between Two Common MRI Metrics of Liver Iron Concentration in Transfusional Siderosis

John C Wood, MD, Ph.D, Amber Jones, Hugh Y Rienhoff, Jr., MD, Ellis J. Neufeld, MD, PhD

Blood (2011) 118 (21): 1088.

https://doi.org/10.1182/blood.V118.21.1088.1088

Published: 2011

Journal Articles

Liver Iron Concentration Estimates by R2* Are More Robust Than by Ferriscan During Rapid Changes in Iron Burden

John C Wood, MD, Ph.D, Amber Jones, Hugh Y Rienhoff, Jr., MD, Ellis J. Neufeld, MD, PhD

Blood (2011) 118 (21): 5296.

https://doi.org/10.1182/blood.V118.21.5296.5296

Published: 2011

Journal Articles

A Phase 1B Dose-Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of FBS0701, a Novel Oral Iron Chelator for the Treatment of Chronic Iron Overload

Hugh Y. Rienhoff, Jr, MD, ip Viprakasit, MD, D, Phil, Lay H. Tay, MBBS, FRCPA, Paul Harmatz, MD, Elliott Vichinsky, MD, Deborah Chirnomas, MD, MPH, Janet Kwiatkowski, MD, Amy E Tapper, PhD, John B Porter, MD, Ellis J. Neufeld, MD, PhD

Blood (2010) 116 (21): 2057.

https://doi.org/10.1182/blood.V116.21.2057.2057

Published: 2010

NARROW

An Enhanced Sensitivity DNA Sequencing Protocol for the Detection in AML of Measurable Residual Disease (MRD) Applicable for All Mutations

Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB

Pharmacologic LSD1 Inhibition Preserves Human Granulocytic While Expanding Monocytic Progenitors

LSD1 inhibition exerts its antileukemic effect by recommissioning PU.1- and C/EBPα-dependent enhancers in AML

The Small Molecule Img-98, a Potent and Selective Inhibitor of the Lysine Demethylase Lsd-1, Effectively Augments the Pro-Differentiation Effects of ATRA in a Pre-Clinical Model of AML

R2 and R2* Are Equally Effective In Evaluating Chronic Response To Iron Chelation

Liver MRI Is Better Than Biopsy For Assessing Total Body Iron Balance: Validation By Simulation

Safety, Tolerability and Dose Response of FBS0701, a Novel Iron Chelator for Treatment of Transfusional Iron Overload: Results of a 24-Week Multicenter, International Phase 2 Study

Disparities Between Two Common MRI Metrics of Liver Iron Concentration in Transfusional Siderosis

Liver Iron Concentration Estimates by R2* Are More Robust Than by Ferriscan During Rapid Changes in Iron Burden

A Phase 1B Dose-Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of FBS0701, a Novel Oral Iron Chelator for the Treatment of Chronic Iron Overload

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American Society of Hematology

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ASH Publications

American Society of Hematology

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