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Journal Articles

ZBTB7A Loss Promotes Synthesis of Lipids and Ketone Bodies in Myeloid Leukemia

Vanessa C. Arfelli, Werner Schmitz, Martin E. Kirmaier, Enric Redondo Monte, Paul Kerbs, Monica Cusan, Sebastian Theurich, Christian Wichmann, Philipp A. Greif

Blood (2023) 142 (Supplement 1): 1390.

https://doi.org/10.1182/blood-2023-185682

Published: 2023

Journal Articles

Synergistic Antileukemic Effect of Mek and Lsd1 Inhibitors Correlates with Decreased Phospho-Serine 315 of TP53

Alessandra Caroleo, Paul Kerbs, Anja Swoboda, Lucas Wange, Stephanie Heinzlmeir, Yun-Chien Chang, Bernhard Küster, Wolfgang Enard, Michael von Bergwelt, Philipp A. Greif, Monica Cusan

Blood (2022) 140 (Supplement 1): 5870–5871.

https://doi.org/10.1182/blood-2022-169202

Published: 2022

Journal Articles

Multi-Dimensional Analysis of Adult Acute Myeloid Leukemia (AML) Landscape Cross-Continents Reveals Age Associated Trends in Mutations and Outcomes

Blood (2021) 138 (Supplement 1): 685.

https://doi.org/10.1182/blood-2021-153015

Published: 2021

Journal Articles

CSF3R T618I Collaborates with RUNX1-RUNX1T1 to Expand Human Haematopoietic Stem and Progenitor Cells

Anja Swoboda, Roland Windisch, Paul Kerbs, Enric Redondo Monte, Johannes W. Bagnoli, Linping Chen-Wichmann, Alessandra Caroleo, Monica Cusan, Wolfgang Enard, Tobias Herold, Christian Wichmann, Philipp A. Greif

Blood (2021) 138 (Supplement 1): 2233.

https://doi.org/10.1182/blood-2021-152295

Published: 2021

Journal Articles

Leukemia Cell of Origin Influences p53 Activity and Therapeutic Sensitivity Via an Evi1-Dependent Mechanism

Blood (2019) 134 (Supplement_1): 109.

https://doi.org/10.1182/blood-2019-122483

Published: 2019

Journal Articles

GATA2 Zinc Finger Mutations Influence Erythroid Differentiation and Chemotherapy Response

Georg Leubolt, MSc, Enric Redondo Monte, MSc, BSc, Anja Wilding, MSc, Paul Kerbs, MSc, Monica Cusan, MD, Johannes Bagnoli, Wolfgang Enard, PhD, Wolfgang Hiddemann, MD PhD, Christian Wichmann, MD, Gunnar Schotta, PhD, Philipp A. Greif, MD PD

Blood (2019) 134 (Supplement_1): 1459.

https://doi.org/10.1182/blood-2019-128218

Published: 2019

Journal Articles

GATA2 Zinc Finger Mutations Affect DNA-Binding and Promote Granulopoietic Differentiation

Georg Leubolt, MSc, Belay Tizazu, Sayantanee Dutta, PhD, Monica Cusan, MD, Theresa Sippenauer, Rouzanna Istvanffy, PhD, Robert A.J. Oostendorp, PhD, Wolfgang Hiddemann, Philipp A. Greif, MD PD

Blood (2018) 132 (Supplement 1): 2779.

https://doi.org/10.1182/blood-2018-99-115976

Published: 2018

Journal Articles

LSD1 inhibition exerts its antileukemic effect by recommissioning PU.1- and C/EBPα-dependent enhancers in AML

Monica Cusan, Sheng F. Cai, Helai P. Mohammad, Andrei Krivtsov, Alan Chramiec, Evangelia Loizou, Matthew D. Witkin, Kimberly N. Smitheman, Daniel G. Tenen, Min Ye, Britta Will, Ulrich Steidl, Ryan G. Kruger, Ross L. Levine, Hugh Y. Rienhoff, Jr, Richard P. Koche, Scott A. Armstrong

Blood (2018) 131 (15): 1730–1742.

https://doi.org/10.1182/blood-2017-09-807024

Published: 2018

Includes: Supplemental data

Journal Articles

LSD1 Inhibition Exerts Its Anti-Leukemic Effect By Recommissioning PU.1- and C/Ebpα-Dependent Enhancers in AML

Monica Cusan, MD, Sheng Cai, MD PhD, Helai P Mohammad, PhD, Andrei V. Krivtsov, PhD, Alan Chramiec, Evangelia Loizou, Daniel G. Tenen, MD, Min Ye, PhD, Britta Will, PhD, Ulrich G. Steidl, MDPhD, Ryan G. Kruger, PhD, Richard Koche, PhD, Scott Armstrong, MD PhD

Blood (2017) 130 (Supplement 1): 242.

https://doi.org/10.1182/blood.V130.Suppl_1.242.242

Published: 2017

Journal Articles

Controlled stem cell amplification by HOXB4 depends on its unique proline-rich region near the N terminus

Monica Cusan, Naidu M. Vegi, Medhanie A. Mulaw, Shiva Bamezai, Lisa M. Kaiser, Aniruddha J. Deshpande, Philipp A. Greif, Leticia Quintanilla-Fend, Stefanie Göllner, Carsten Müller-Tidow, Keith R. Humphries, Scott A. Armstrong, Wolfgang Hiddemann, Michaela Feuring-Buske, Christian Buske

Blood (2017) 129 (3): 319–323.

https://doi.org/10.1182/blood-2016-04-706978

Published: 2017

Includes: Supplemental data

Journal Articles

An Epigenetic Regulator Screen Identifies Novel Targets That Sensitize MLL -Rearranged Leukemia to DOT1L Inhibition

Blood (2016) 128 (22): 571.

https://doi.org/10.1182/blood.V128.22.571.571

Published: 2016

Journal Articles

Inhibition Of LSD1 As a Therapeutic Strategy For The Treatment Of Acute Myeloid Leukemia

Blood (2013) 122 (21): 3964.

https://doi.org/10.1182/blood.V122.21.3964.3964

Published: 2013

Journal Articles

AML1-ETO Collaborates with the Homeobox Gene Meis1 in Inducing Acute Leukemia in the Mouse Bone Marrow Transplantation Model.

Vegi M. Naidu, MSc, Vijay P.S. Rawat, PhD, Christina Schessl, PhD, Konstantin Petropoulus, PhD, Monica Cusan, Aniruddha J Deshpande, PhD, Leticia Quintanilla Martinez, MD, Wolfgang Hiddemann, Michaela Feuring Buske, MD, Christian Buske, MD

Blood (2008) 112 (11): 928.

https://doi.org/10.1182/blood.V112.11.928.928

Published: 2008

Journal Articles

Bi-Phenotypic Leukemic Cells as Transient Intermediates Between Leukemic Stem Cells with Lymphoid Characteristics and the Leukemic Myeloid Bulk: Insights from a Murine Model of CALM/AF10 Positive Acute Myeloid Leukemia

Aniruddha Deshpande, Hendrik Reuter, Medhanie Mulaw, Monica Cusan, Wolfgang Hiddemann, Stefan Bohlander, Michaela Feuring-Buske, Christian Buske

Blood (2008) 112 (11): 506.

https://doi.org/10.1182/blood.V112.11.506.506

Published: 2008

Journal Articles

The Deletion of the Proline-Rich Region of HOXB4 Is Associated with Myeloid Leukemia in a Mouse Model

Monica Cusan, Aniruddha Deshpande, Vijay Rawat, Wolfgang Hiddemann, Leticia Quintanilla-Martinez, MD, R. Keith Humphries, MD, PhD, Christian Buske, MD, Michaela Feuring-Buske

Blood (2008) 112 (11): 507.

https://doi.org/10.1182/blood.V112.11.507.507

Published: 2008

Journal Articles

Functional analysis of the Human Pbx Interacting Protein (HPIP) in Human Hematopoiesis

Pawandeep Kaur, M.Sc(Hons), Christiane Stadler, PhD, Farid Ahmed, PhD, Monica Cusan, MTA, R. Keith Humphries, MD, PhD, Wolfgang Hiddemann, MD, Christian Buske, PD.med, Michaela Feuring-Buske, PD.med

Blood (2008) 112 (11): 2430.

https://doi.org/10.1182/blood.V112.11.2430.2430

Published: 2008

Journal Articles

The Hematopoietic Activity of the Homeobox Gene HOXB4 Depends on a N-Terminal Proline-Rich Region In Vitro and In Vivo .

Monica Cusan, Aniruddha Deshpande, PhD, Wolfgang Hiddemann, MD, R. Keith Humphries, MD, Christian Buske, MD, Michaela Feuring-Buske, MD

Blood (2006) 108 (11): 1333.

https://doi.org/10.1182/blood.V108.11.1333.1333

Published: 2006

Journal Articles

A Lymphoid Progenitor Propagates AML in a Mouse Model of CALM/AF10 Positive Leukemia.

Aniruddha Deshpande, Monica Cusan, Viajy P.S. Rawat, Hendrik Reuter, Leticia Quintanilla-Martinez, Alexandre Krause, Wolfgang Hiddemann, Peter Lichter, Stefan K. Bohlander, R. Keith Humphries, Michaela Feuring-Buske, Christian Buske

Blood (2005) 106 (11): 101.

https://doi.org/10.1182/blood.V106.11.101.101

Published: 2005

Journal Articles

The AML1-ETO Fusion Gene and the FLT3 Length Mutation Collaborate in Inducing Acute Leukemia in a Murine Bone Marrow Transplantation Model.

Christina Schessl, Vijay P.S. Rawat, Monica Cusan, Aniruddha Deshpande, Tobias M. Kohl, Patricia M. Rosten, Karsten Spiekermann, R.Keith Humphries, Susanne Schnittger, Wolfgang Kern, Wolfgang Hiddemann, Leticia Quintanilla-Martinez, Stefan K. Bohlander, Michaela Feuring-Buske, Christian Buske

Blood (2005) 106 (11): 100.

https://doi.org/10.1182/blood.V106.11.100.100

Published: 2005

Journal Articles

The Oncogenic Potential of the Homeobox Gene Cdx2 Is Depending on the MAPK Pathway and Can Be Antagonized by the MEK1/2 Inhibitor PD98059 in a Mouse Model of t(12;13)(p13;q12) Positive AML.

Vijay P.S. Rawat, Vegi M. Naidu, Christina Schessl, Monica Cusan, R.Keith Humphries, Ph.D, J. P. Lynch, Ph.D, W. Hiddemann, MD, Ph.D., Michaela Feuring-Buske, MD, Christian Buske, MD

Blood (2004) 104 (11): 1975.

https://doi.org/10.1182/blood.V104.11.1975.1975

Published: 2004

NARROW

ZBTB7A Loss Promotes Synthesis of Lipids and Ketone Bodies in Myeloid Leukemia

Synergistic Antileukemic Effect of Mek and Lsd1 Inhibitors Correlates with Decreased Phospho-Serine 315 of TP53

Multi-Dimensional Analysis of Adult Acute Myeloid Leukemia (AML) Landscape Cross-Continents Reveals Age Associated Trends in Mutations and Outcomes

CSF3R T618I Collaborates with RUNX1-RUNX1T1 to Expand Human Haematopoietic Stem and Progenitor Cells

Leukemia Cell of Origin Influences p53 Activity and Therapeutic Sensitivity Via an Evi1-Dependent Mechanism

GATA2 Zinc Finger Mutations Influence Erythroid Differentiation and Chemotherapy Response

GATA2 Zinc Finger Mutations Affect DNA-Binding and Promote Granulopoietic Differentiation

LSD1 inhibition exerts its antileukemic effect by recommissioning PU.1- and C/EBPα-dependent enhancers in AML

LSD1 Inhibition Exerts Its Anti-Leukemic Effect By Recommissioning PU.1- and C/Ebpα-Dependent Enhancers in AML

Controlled stem cell amplification by HOXB4 depends on its unique proline-rich region near the N terminus

An Epigenetic Regulator Screen Identifies Novel Targets That Sensitize MLL -Rearranged Leukemia to DOT1L Inhibition

Inhibition Of LSD1 As a Therapeutic Strategy For The Treatment Of Acute Myeloid Leukemia

AML1-ETO Collaborates with the Homeobox Gene Meis1 in Inducing Acute Leukemia in the Mouse Bone Marrow Transplantation Model.

Bi-Phenotypic Leukemic Cells as Transient Intermediates Between Leukemic Stem Cells with Lymphoid Characteristics and the Leukemic Myeloid Bulk: Insights from a Murine Model of CALM/AF10 Positive Acute Myeloid Leukemia

The Deletion of the Proline-Rich Region of HOXB4 Is Associated with Myeloid Leukemia in a Mouse Model

Functional analysis of the Human Pbx Interacting Protein (HPIP) in Human Hematopoiesis

The Hematopoietic Activity of the Homeobox Gene HOXB4 Depends on a N-Terminal Proline-Rich Region In Vitro and In Vivo .

A Lymphoid Progenitor Propagates AML in a Mouse Model of CALM/AF10 Positive Leukemia.

The AML1-ETO Fusion Gene and the FLT3 Length Mutation Collaborate in Inducing Acute Leukemia in a Murine Bone Marrow Transplantation Model.

The Oncogenic Potential of the Homeobox Gene Cdx2 Is Depending on the MAPK Pathway and Can Be Antagonized by the MEK1/2 Inhibitor PD98059 in a Mouse Model of t(12;13)(p13;q12) Positive AML.

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American Society of Hematology

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American Society of Hematology

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