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Journal Articles

The Battle within: AML´s p53 Strategies to Evade T-Cell Attack

Lis Winter, Lea Pawlowsky, Anetta Marcinek, Bettina Brauchle, Amelie Muth, Maryam Kazerani, Agnese Petrera, Roman Kischel, Alica Joana Emhardt, Maja Rothenberg-Thurley, Annika Maria Dufour, Karsten Spiekermann, Michael Andreeff, Naval Daver, Veit L. Buecklein, Marion Subklewe
Journal: Blood
Blood (2023) 142 (Supplement 1): 1411.
https://doi.org/10.1182/blood-2023-173826
Published: 2023
Journal Articles

D DX41 -Low Expression Mimics Germline DDX41 -Phenotype in Acute Myeloid Leukemia

Wajma Shahbaz, Vindi Jurinovic, Aarif M. N. Batcha, Christian Rausch, Maja Rothenberg-Thurley, Annika Maria Dufour, Bianka Ksienzyk, Stephanie Schneider, Michaela Neusser, Maria Cristina Sauerland, Dennis Görlich, Wolfgang E. Berdel, Bernhard J. Woermann, Utz Krug, Jan Braess, Wolfgang Hiddemann, Ulrich Mansmann, Sebastian Vosberg, Philipp A. Greif, Karsten Spiekermann, Klaus H Metzeler, Tobias Herold
Journal: Blood
Blood (2023) 142 (Supplement 1): 820.
https://doi.org/10.1182/blood-2023-187419
Published: 2023
Journal Articles

Risk Stratification of Patients with RUNX1- mutated Acute Myeloid Leukemia

Christian Rausch, Roman Hornung, Aarif M. N. Batcha, Maja Rothenberg-Thurley, Stefanos A. Bamopoulos, Vindi Jurinovic, Bianka Ksienzyk, Stephanie Schneider, Annika Maria Dufour, Michaela Neusser, Maria Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard J. Woermann, Jan Braess, Wolfgang Hiddemann, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Johannes Schetelig, Moritz Middeke, Sebastian Stasik, Katharina Egger-Heidrich, Christoph Röllig, Martin Bornhäuser, Christian Thiede, Claudia D Baldus, Carsten Müller-Tidow, Uwe Platzbecker, Hubert Serve, Wendy Stock, Geoffrey L Uy, John C. Byrd, Deedra Nicolet, Ann-Kathrin Eisfeld, Ulrich Mansmann, Karsten Spiekermann, Klaus H Metzeler, Tobias Herold
Journal: Blood
Blood (2023) 142 (Supplement 1): 2934.
https://doi.org/10.1182/blood-2023-174059
Published: 2023
Journal Articles

WT1 and DNMT3A play essential roles in the growth of certain patient AML cells in mice

Maryam Ghalandary, Yuqiao Gao, Diana Amend, Ginte Kutkaite, Binje Vick, Karsten Spiekermann, Maja Rothenberg-Thurley, Klaus H. Metzeler, Anetta Marcinek, Marion Subklewe, Michael P. Menden, Vindi Jurinovic, Ehsan Bahrami, Irmela Jeremias
Journal: Blood
Blood (2023) 141 (8): 955–960.
https://doi.org/10.1182/blood.2022016411
Published: 2023
Includes: Supplemental data
Journal Articles

Acute Myeloid Leukemia with Isolated Trisomy 4 Is Characterized By Frequent Mutations of TET2 and a Distinct DNA Methylation Signature

Sayantanee Dutta, Paul Kerbs, Maja Rothenberg-Thurley, Bianka Ksienzyk, Stefan Krebs, Helmut Blum, Karsten Spiekermann, Klaus H. Metzeler, Tobias Herold, Sebastian Vosberg, Philipp A. Greif
Journal: Blood
Blood (2022) 140 (Supplement 1): 8912–8913.
https://doi.org/10.1182/blood-2022-168939
Published: 2022
Journal Articles

Presence of Measurable Residual Disease in NPM1 Positive AML in Remission Pre-Transplant Does Not Impact on Survival after Allogeneic Hematopoietic Stem Cell Transplantation

Alessia Fraccaroli, Elena Stauffer, Katrin Koch, Klaus Hirschbühl, Stephan Breitkopf, Frank Ziemann, Heidrun Drolle, Maja Rothenberg-Thurley, Annika Maria Dufour, Klaus H. Metzeler, Michael von Bergwelt, Karsten Spiekermann, Andreas Hausmann, Christoph Schmid, Mareike Verbeek, Tobias Herold, Johanna Tischer
Journal: Blood
Blood (2022) 140 (Supplement 1): 4882–4883.
https://doi.org/10.1182/blood-2022-167299
Published: 2022
Journal Articles

Secondary Neoplasms in AML Long-Term Survivors: Even More Cancer to Come?

Anna Sophia Moret, Eva Telzerow, Maria Cristina Sauerland, Simon M. Krauss, Maja Rothenberg-Thurley, Friederike H.A. Mumm, Jan Braess, Bernhard J. Wörmann, Utz Krug, Wolfgang E. Berdel, Wolfgang Hiddemann, Karsten Spiekermann, Pia Heußner, Dennis Görlich, Klaus H. Metzeler
Journal: Blood
Blood (2022) 140 (Supplement 1): 690–691.
https://doi.org/10.1182/blood-2022-163530
Published: 2022
Journal Articles

Alterations of Human Bone Marrow Niche in Clonal Hematopoiesis and AML

Yana Dragieva, Maja Rothenberg-Thurley, Bianka Ksienzyk, Amar Hadzic, Alexander Paulus, Benjamin Tast, Maryam Kazerani, Marion Subklewe, Stephanie Schneider, Karsten Spiekermann, Sebastian Theurich, Klaus H. Metzeler, Maria Solovey, Frank Ziemann
Journal: Blood
Blood (2022) 140 (Supplement 1): 11430–11431.
https://doi.org/10.1182/blood-2022-167168
Published: 2022
Journal Articles

Life Satisfaction and Quality of Life in AML Long-Term Survivors: Primary Results of the AMLCG-Survivorship Study

Eva Telzerow, Dennis Görlich, Maria Cristina Sauerland, Anna Sophia Moret, Maja Rothenberg-Thurley, Simon M. Krauss, Friederike H.A. Mumm, Susanne Amler, Wolfgang E. Berdel, Bernhard J. Wörmann, Utz Krug, Jan Braess, Pia Heußner, Wolfgang Hiddemann, Karsten Spiekermann, Klaus H. Metzeler
Journal: Blood
Blood (2022) 140 (Supplement 1): 5293–5295.
https://doi.org/10.1182/blood-2022-165429
Published: 2022
Journal Articles

German AMLCG-Survivorship Study: Anxiety and Depression Symptoms in AML Long-Term Survivors

Dennis Görlich, Eva Telzerow, Maria Cristina Sauerland, Anna Sophia Moret, Maja Rothenberg-Thurley, Friederike H.A. Mumm, Susanne Amler, Wolfgang E. Berdel, Bernhard J. Wörmann, Utz Krug, Jan Braess, Pia Heußner, Wolfgang Hiddemann, Karsten Spiekermann, Klaus H. Metzeler
Journal: Blood
Blood (2022) 140 (Supplement 1): 942–943.
https://doi.org/10.1182/blood-2022-156647
Published: 2022
Journal Articles

Sex-Associated Differences in Frequencies and Outcome Prognostication of Recurrent Molecular Features in Adults with Acute Myeloid Leukemia (AML) (AMLCG, CALGB [Alliance])

Michael P. Ozga, Deedra Nicolet, Krzysztof Mrózek, Selen Yilmaz, Jessica Kohlschmidt, Karilyn T. Larkin, James S. Blachly, Christopher C. Oakes, Jill Buss, Christopher J. Walker, Shelley Orwick, Vindi Jurinovic, Maja Rothenberg-Thurley, Annika Maria Dufour, Stephanie Schneider, Maria Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard Josef Woermann, Wolfgang Hiddemann, Jan Braess, Marion Subklewe, Karsten Spiekermann, Andrew J. Carroll, William G. Blum, Bayard L. Powell, Jonathan E. Kolitz, Joseph O. Moore, Robert James Mayer, Richard M. Stone, Geoffrey L. Uy, Wendy Stock, Klaus H. Metzeler, H. Leighton Grimes, John C. Byrd, Nathan Salomonis, Tobias Herold, Alice S. Mims, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2022) 140 (Supplement 1): 936–939.
https://doi.org/10.1182/blood-2022-165395
Published: 2022
Journal Articles

Validation of the 2022 European Leukemianet Genetic Risk Stratification of Acute Myeloid Leukemia

Christian Rausch, Maja Rothenberg-Thurley, Annika Maria Dufour, Stephanie Schneider, Hanna Gittinger, Maria Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard Josef Woermann, Wolfgang Hiddemann, Jan Braess, Karsten Spiekermann, Tobias Herold, Klaus H. Metzeler
Journal: Blood
Blood (2022) 140 (Supplement 1): 3408–3409.
https://doi.org/10.1182/blood-2022-167022
Published: 2022
Journal Articles

WT1 and DNMT3A Play an Essential Function and Represent Therapeutic Vulnerabilities in Certain AML Samples, As Shown By CRISPR/Cas9 Mediated Knockout in PDX Models In Vivo

Maryam Ghalandary, Yuqiao Gao, Martin Becker, Diana Amend, Klaus H. Metzeler, Maja Rothenberg-Thurley, Irmela Jeremias
Journal: Blood
Blood (2021) 138 (Supplement 1): 377.
https://doi.org/10.1182/blood-2021-150305
Published: 2021
Journal Articles

Quality of Life and Life Satisfaction in AML Long-Term Survivors: Primary Results of the AMLCG-Survivorship Study

Eva Telzerow, Dennis Görlich, Maja Rothenberg-Thurley, Maria Cristina Sauerland, Anna Sophia Moret, Friederike H. A. Mumm, Susanne Amler, Wolfgang E. Berdel, Bernhard J. Wörmann, Utz Krug, Jan Braess, Pia Heußner, Wolfgang Hiddemann, Karsten Spiekermann, Klaus H. Metzeler
Journal: Blood
Blood (2021) 138 (Supplement 1): 2289.
https://doi.org/10.1182/blood-2021-147027
Published: 2021
Journal Articles

Multi-Dimensional Analysis of Adult Acute Myeloid Leukemia (AML) Landscape Cross-Continents Reveals Age Associated Trends in Mutations and Outcomes

Monica Cusan, Karilyn Larkin, Deedra Nicolet, Vindi Jurinovic, Krzysztof Mrózek, Aarif M. N. Batcha, Maja Rothenberg-Thurley, Stephanie Schneider, Maria Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard Josef Woermann, Wolfgang Hiddemann, Jan Braess, Karsten Spiekermann, Jessica Kohlschmidt, James S. Blachly, Alice S. Mims, Christopher J. Walker, Christopher C. Oakes, Shelley Orwick, Andrew J Carroll, William Blum, Bayard L. Powell, Jonathan E Kolitz, Joseph O. Moore, Robert James Mayer, Richard A. Larson, Richard M. Stone, John C. Byrd, Klaus H. Metzeler, Tobias Herold, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2021) 138 (Supplement 1): 685.
https://doi.org/10.1182/blood-2021-153015
Published: 2021
Journal Articles

Characterization of Somatic Mosaicism and Mutational Profiling of Clonal Hematopoiesis Compared to MDS and sAML Depicts Diversities of Clonal Evolution

Judith S. Hecker, Luise Hartmann, Maja Rothenberg-Thurley, Jennifer Rivière, Bianka Ksienzyk, Michele C. Buck, Mark Van Der Garde, Luise Fischer, Susann Winter, Martina Rauner, Elena Tsourdi, Katja Sockel, Marie Schneider, Anne Sophie Kubasch, Martin Nolde, Dominikus Hausmann, Jörg Lützner, Andreas Roth, Florian Bassermann, Karsten Spiekermann, Lorenz Hofbauer, Uwe Platzbecker, Klaus H. Metzeler, Katharina S. Goetze
Journal: Blood
Blood (2021) 138 (Supplement 1): 3278.
https://doi.org/10.1182/blood-2021-152187
Published: 2021
Journal Articles

High Prevalence of CHF and Diabetes in AML Long-Term Survivors - a Patient Forever?

Anna Sophia Moret, Eva Telzerow, Maja Rothenberg-Thurley, Maria Cristina Sauerland, Elke Burgard, Friederike H. A. Mumm, Jan Braess, Bernhard J. Wörmann, Utz Krug, Wolfgang E. Berdel, Wolfgang Hiddemann, Karsten Spiekermann, Pia Heußner, Klaus Kraywinkel, Dennis Görlich, Klaus H. Metzeler
Journal: Blood
Blood (2021) 138 (Supplement 1): 4127.
https://doi.org/10.1182/blood-2021-149149
Published: 2021
Journal Articles

CHIP and hips: clonal hematopoiesis is common in patients undergoing hip arthroplasty and is associated with autoimmune disease

Brief Report
Judith S. Hecker, Luise Hartmann, Jennifer Rivière, Michèle C. Buck, Mark van der Garde, Maja Rothenberg-Thurley, Luise Fischer, Susann Winter, Bianka Ksienzyk, Frank Ziemann, Maria Solovey, Martina Rauner, Elena Tsourdi, Katja Sockel, Marie Schneider, Anne S. Kubasch, Martin Nolde, Dominikus Hausmann, Alexander C. Paulus, Jörg Lützner, Andreas Roth, Florian Bassermann, Karsten Spiekermann, Carsten Marr, Lorenz C. Hofbauer, Uwe Platzbecker, Klaus H. Metzeler, Katharina S. Götze
Journal: Blood
Blood (2021) 138 (18): 1727–1732.
https://doi.org/10.1182/blood.2020010163
Published: 2021
Includes: Supplemental data
Journal Articles

PTPN11 mutations and Outcomes in Adult Patients with Acute Myeloid Leukemia

Klaus H. Metzeler, MD, Maja Rothenberg-Thurley, PhD, Dennis Görlich, PhD, Maria Cristina Sauerland, Annika Maria Dufour, PhD, Stephanie Schneider, PhD, Marion Subklewe, MD, Jan Braess, MD, Bernhard J. Wörmann, MD, Wolfgang E. Berdel, Prof., MD, Utz Krug, MD, Wolfgang Hiddemann, MD PhD, Karsten Spiekermann, MD, Tobias Herold, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4–5.
https://doi.org/10.1182/blood-2020-137487
Published: 2020
Journal Articles

Single Cell Clones Derived from a Patient's AML Xenograft Display Genetic and Functional Heterogeneity

Christina Maria Zeller, MSc, Daniel Richter, MSc, Binje Vick, PhD, Tobias Herold, MD, Johannes Bagnoli, Maja Rothenberg-Thurley, PhD, Klaus H. Metzeler, MD, Karsten Spiekermann, MD, Wolfgang Enard, PhD, Irmela Jeremias, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1450.
https://doi.org/10.1182/blood-2019-127867
Published: 2019