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Journal Articles

Mitapivat Improves Markers of Erythropoietic Activity in Long-Term Study of Adults with Alpha- or Beta-Non-Transfusion-Dependent Thalassemia

Kevin H.M. Kuo, D. Mark Layton, Ashutosh Lal, Hanny Al-Samkari, Penelope A. Kosinski, Bo Tong, Jeremie H. Estepp, Katrin Uhlig, Elliott P. Vichinsky

Blood (2022) 140 (Supplement 1): 2479–2480.

https://doi.org/10.1182/blood-2022-163493

Published: 2022

Journal Articles

Hydroxyurea Dosing in Very Young Children (HUGKISS): Challenges of Study Design

Meghna Dua, Winfred C. Wang, Timothy McCavit, Suvankar Majumdar, R. Clark Brown, Zora R. Rogers, Jeffrey Gossett, Guolian Kang, Jeremie H. Estepp

Blood (2022) 140 (Supplement 1): 11108–11109.

https://doi.org/10.1182/blood-2022-165760

Published: 2022

Journal Articles

Hydroxyurea Dosing in Very Young Children with Sickle Cell Anemia: A Multicenter, Randomized, Controlled Trial (HUGKISS)

Meghna Dua, Winfred C. Wang, R. Clark Brown, Melissa A. McNaull, Zora R. Rogers, Martha Barton, Jane Hankins, Jeffrey Gossett, Julie Richardson, Jerlym S. Porter, Guolian Kang, Jeremie H. Estepp

Blood (2022) 140 (Supplement 1): 445–446.

https://doi.org/10.1182/blood-2022-160485

Published: 2022

Journal Articles

Association of Thrombospondin-1 Gene Polymorphism with Elevated Tricuspid Regurgitant Velocity in Sickle Cell Anemia

Parul Rai, Sara Rashkin, Victoria I Okhomina, Vijaya Joshi, Kenneth I. Ataga, Jane S Hankins, Guolian Kang, Jeremie H. Estepp

Blood (2021) 138 (Supplement 1): 2027.

https://doi.org/10.1182/blood-2021-150845

Published: 2021

Journal Articles

Social Determinants of Health and Neurocognitive Functioning in Sickle Cell Disease

Andrew M Heitzer, Jennifer Longoria, Victoria I Okhomina, Jerlym S. Porter, Jeremie H. Estepp, Robert L Davis, Guolian Kang, Jane S Hankins

Blood (2021) 138 (Supplement 1): 2030.

https://doi.org/10.1182/blood-2021-145787

Published: 2021

Journal Articles

FT-4202, an Allosteric Activator of Pyruvate Kinase-R, Demonstrates Proof of Mechanism and Proof of Concept after a Single Dose and after Multiple Daily Doses in a Phase 1 Study of Patients with Sickle Cell Disease

R. Clark Brown, MD PhD, Kimberly Cruz, MD MS, Theodosia A. Kalfa, MD PhD, Frans A. Kuypers, PhD, Santosh L. Saraf, MD, Jeremie H. Estepp, MD, Luke R. Smart, MD, Punam Malik, MD, Mark Lerman, MD, Renae Mayer, MD, Maria D. Ribadeneira, PhD, Sanjeev Forsyth, MS, Patricia Schroeder, PhD, Eric Wu, PhD, Patrick Kelly, MD, Marilyn J. Telen, MD

Blood (2020) 136 (Supplement 1): 19–20.

https://doi.org/10.1182/blood-2020-134269

Published: 2020

Journal Articles

An Adaptive, Randomized, Placebo-Controlled, Double-Blind, Multi-Center Study of Oral FT-4202, a Pyruvate Kinase Activator in Patients with Sickle Cell Disease (PRAISE)

Kenneth W. Wood, PhD, James Geib, BS, Eric Wu, PhD, Jason Berlin, MS, Irena Webster, MPH, MA, Kenneth I. Ataga, MD, Jo Howard, MBBChir, MRCP, FRCPath, Jeremie H. Estepp, MD, Marilyn J. Telen, MD, Julie Brevard, MPH

Blood (2020) 136 (Supplement 1): 19–20.

https://doi.org/10.1182/blood-2020-134266

Published: 2020

Journal Articles

Food Deserts Are Associated with Acute Care Utilization Among Preschool Children with Sickle Cell Disease

Hamda Khan, MA, Nariman Ammar, PhD, Jerlym S. Porter, PhD MPH, Juan Ding, PhD, Jeremie H. Estepp, MD, Jason R. Hodges, PhD MA, Arash Shaban-Nejad, PhD MPH, Winfred Wang, MD, James G Gurney, PhD, Guolian Kang, PhD, Robert Davis, MD MPH, Jane S. Hankins, MD MS

Blood (2020) 136 (Supplement 1): 19.

https://doi.org/10.1182/blood-2020-138802

Published: 2020

Journal Articles

Fetal Hemoglobin Mediates the Effect of Beta Globin Gene Polymorphisms on Neurocognitive Functioning in Sickle Cell Disease

Andrew M Heitzer, PhD, Jennifer Longoria, PhD, Evadnie Rampersaud, PhD, Sara Rashkin, PhD, Jeremie H. Estepp, MD, Victoria Okhomina, MS, Winfred Wang, MD, Darcy Raches, PhD, Brian Potter, PhD, Allison A. King, MDMPH,PhD, Guolian Kang, PhD, Jane S. Hankins, MD MS

Blood (2020) 136 (Supplement 1): 23–24.

https://doi.org/10.1182/blood-2020-137065

Published: 2020

Journal Articles

Disease Modeling and Phenotype Rescue Using Inducible Pluripotent Stem Cells from Patients with Diamond-Blackfan Anemia

Senthil Velan Bhoopalan, MD PhD, Min-Joon Han, PhD, Steven Ellis, PhD, Harry Lesmana, MD, Jeremie H. Estepp, MD, Yoonjeong Jang, DVM,PhD, Mitchell J. Weiss, MD PhD, Marcin W. Wlodarski, MD PhD

Blood (2019) 134 (Supplement_1): 2496.

https://doi.org/10.1182/blood-2019-131354

Published: 2019

Journal Articles

Progression of Central Nervous System Vasculopathy in Young Adults with Sickle Cell Anemia

Grace Champlin, MD, Scott Hwang, MD PhD, Guolian Kang, PhD, Juan Ding, PhD, Jeremie H. Estepp, MD, Kenneth I. Ataga, MD, Curtis L. Owens, MD, Justin Newman, MD, Lisa M. Jacola, PhD ABPP-CN, Allison A. King, MD MPH, PhD, Robert Davis, MD MPH, Winfred Wang, MD, Jane S. Hankins, MD MS

Blood (2019) 134 (Supplement_1): 2290.

https://doi.org/10.1182/blood-2019-129193

Published: 2019

Journal Articles

Transcranial Doppler Velocities Conversion Rate Based on Increasing Hemoglobin Concentration: Analysies from the SCCRIP Cohort Study

Jeremie H. Estepp, MD, Ze Cong, PhD, Irene Agodoa, MD, Guolian Kang, PhD, Juan Ding, PhD, M. Beth McCarville, MD, Jane S. Hankins, MD MS, Winfred Wang, MD

Blood (2019) 134 (Supplement_1): 1002.

https://doi.org/10.1182/blood-2019-131177

Published: 2019

Journal Articles

Children with Sickle Cell Anemia and APOL1 Gene Variants Develop Albuminuria Early in Life

Rima Zahr, DO, Jeffrey Lebensburger, DO, MSPH, Evadnie Rampersaud, PhD, Jane S. Hankins, MD MS, Jeremie H. Estepp, MD

Blood (2018) 132 (Supplement 1): 2377.

https://doi.org/10.1182/blood-2018-99-118912

Published: 2018

Journal Articles

Precision Medicine for Sickle Cell Disease through Whole Genome Sequencing

Blood (2018) 132 (Supplement 1): 3641.

https://doi.org/10.1182/blood-2018-99-117606

Published: 2018

Journal Articles

Fetal Hemoglobin Level during Hydroxyurea Therapy Varies By Neighborhood

Jason R Hodges, PhD MA, Martha Villavicencio, PhD, Jeremie H. Estepp, MD, Jane S. Hankins, MD MS

Blood (2018) 132 (Supplement 1): 2221.

https://doi.org/10.1182/blood-2018-99-119165

Published: 2018

Journal Articles

Insulin-like Growth Factor Binding Protein-3 (IGFBP3) Induces Fetal Hemoglobin in Hematopoietic Stem and Progenitor Cells from Patients with Sickle Cell Anemia

Alireza Paikari, MD, Tian Mi, PhD, Yankai Zhang, PhD, Evadnie Rampersaud, PhD, Guolian Kang, PhD, Gang Wu, PhD, Jane S. Hankins, MD MS, Jeremie H. Estepp, MD, Pavel Sumazin, PhD, Mitchell J. Weiss, MD PhD, Vivien A Sheehan, MD PhD

Blood (2018) 132 (Supplement 1): 722.

https://doi.org/10.1182/blood-2018-99-115383

Published: 2018

Journal Articles

Data Access and Interactive Visualization of Whole Genome Sequence of Sickle Cell Patients within the St. Jude Cloud

Blood (2018) 132 (Supplement 1): 723.

https://doi.org/10.1182/blood-2018-99-116597

Published: 2018

Journal Articles

Effects of Hydroxyurea (HU) on Neurocognitive Performance in Children with Sickle Cell Disease: A Prospective Trial

Winfred Wang, MD, Jane Schreiber, PhD, Guolian Kang, PhD, Chen Li, MS, Jane S Hankins, MD MS, Jeremie H. Estepp, MD, Kathleen Helton, MD

Blood (2017) 130 (Supplement 1): 760.

https://doi.org/10.1182/blood.V130.Suppl_1.760.760

Published: 2017

Journal Articles

Hydroxyurea at Maximal Tolerated Dose (MTD) Prior to Completion of the β-Globin Switch Has Additive but Not Sustained Benefits in Fetal Hemoglobin Production

Christina Abrams, MD, Joseph Moen, MS, Guolian Kang, PhD, Winfred C. Wang, MD, Jane Hankins, MD MS, Jeremie H. Estepp, MD

Blood (2016) 128 (22): 125.

https://doi.org/10.1182/blood.V128.22.125.125

Published: 2016

Journal Articles

Pharmacokinetics in Children with Sickle Cell Anemia Following Single Dose Versus Chronic Treatment with Hydroxyurea

Joana Marie Mack, MD, Pawel Wiczling, PhD, Joseph Moen, MS, Guolian Kang, PhD, Robert I. Liem, MD MS, Julie A. Panepinto, MD MSPH, Gregory Kearns, PharmD, PhD FCP, FAAP, Kathleen A Neville, MD MS, Jeremie H. Estepp, MD

Blood (2016) 128 (22): 1314.

https://doi.org/10.1182/blood.V128.22.1314.1314

Published: 2016

NARROW

Mitapivat Improves Markers of Erythropoietic Activity in Long-Term Study of Adults with Alpha- or Beta-Non-Transfusion-Dependent Thalassemia

Hydroxyurea Dosing in Very Young Children (HUGKISS): Challenges of Study Design

Hydroxyurea Dosing in Very Young Children with Sickle Cell Anemia: A Multicenter, Randomized, Controlled Trial (HUGKISS)

Association of Thrombospondin-1 Gene Polymorphism with Elevated Tricuspid Regurgitant Velocity in Sickle Cell Anemia

Social Determinants of Health and Neurocognitive Functioning in Sickle Cell Disease

FT-4202, an Allosteric Activator of Pyruvate Kinase-R, Demonstrates Proof of Mechanism and Proof of Concept after a Single Dose and after Multiple Daily Doses in a Phase 1 Study of Patients with Sickle Cell Disease

An Adaptive, Randomized, Placebo-Controlled, Double-Blind, Multi-Center Study of Oral FT-4202, a Pyruvate Kinase Activator in Patients with Sickle Cell Disease (PRAISE)

Food Deserts Are Associated with Acute Care Utilization Among Preschool Children with Sickle Cell Disease

Fetal Hemoglobin Mediates the Effect of Beta Globin Gene Polymorphisms on Neurocognitive Functioning in Sickle Cell Disease

Disease Modeling and Phenotype Rescue Using Inducible Pluripotent Stem Cells from Patients with Diamond-Blackfan Anemia

Progression of Central Nervous System Vasculopathy in Young Adults with Sickle Cell Anemia

Transcranial Doppler Velocities Conversion Rate Based on Increasing Hemoglobin Concentration: Analysies from the SCCRIP Cohort Study

Children with Sickle Cell Anemia and APOL1 Gene Variants Develop Albuminuria Early in Life

Precision Medicine for Sickle Cell Disease through Whole Genome Sequencing

Fetal Hemoglobin Level during Hydroxyurea Therapy Varies By Neighborhood

Insulin-like Growth Factor Binding Protein-3 (IGFBP3) Induces Fetal Hemoglobin in Hematopoietic Stem and Progenitor Cells from Patients with Sickle Cell Anemia

Data Access and Interactive Visualization of Whole Genome Sequence of Sickle Cell Patients within the St. Jude Cloud

Effects of Hydroxyurea (HU) on Neurocognitive Performance in Children with Sickle Cell Disease: A Prospective Trial

Hydroxyurea at Maximal Tolerated Dose (MTD) Prior to Completion of the β-Globin Switch Has Additive but Not Sustained Benefits in Fetal Hemoglobin Production

Pharmacokinetics in Children with Sickle Cell Anemia Following Single Dose Versus Chronic Treatment with Hydroxyurea

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American Society of Hematology

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ASH Publications

American Society of Hematology

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