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Journal Articles

In Vitro andpre-Clinical In Vivo evidence Support MDMX/MDM2 As Common Vulnerabilities across TP53 -Wild-Type T-Cell Lymphomas That Are Targetable with the α-Helical p53 Stapled Peptide Alrn-6924

Raphael Koch, MD, Amanda L Christie, BS, Noriaki Yoshida, MD PhD, Samuel Y. Ng, MDPhD, Kay Shigemori, Sara N Morrow, Alexandria Van Scoyk, Steven M. Horwitz, MD, Eric Jacobsen, MD, Solimar Santiago, Jian-Guo Ren, Vincent Guerlavais, PhD, D. Allan Annis, Manuel A. Aivado, MD PhD, David M. Weinstock, MD

Blood (2017) 130 (Supplement 1): 571.

https://doi.org/10.1182/blood.V130.Suppl_1.571.571

Published: 2017

Journal Articles

A Two-Site Interaction Underpins TRIM25 Activation of the RIG-I Anti-Viral Response

Akshay A D'Cruz, Nadia J Kershaw, Edmond M Linossi, Jessica J Chiang, May K Wang, Laura F Dagley, Ben A Croker, Jian-Guo Zhang, Michaela U Gack, Nicos A Nicola, Jeffrey J Babon, Sandra E Nicholson

Blood (2014) 124 (21): 1580.

https://doi.org/10.1182/blood.V124.21.1580.1580

Published: 2014

Journal Articles

The polycomb repressive complex 2 governs life and death of peripheral T cells

Yuxia Zhang, Sarah Kinkel, Jovana Maksimovic, Esther Bandala-Sanchez, Maria C. Tanzer, Gaetano Naselli, Jian-Guo Zhang, Yifan Zhan, Andrew M. Lew, John Silke, Alicia Oshlack, Marnie E. Blewitt, Leonard C. Harrison

Blood (2014) 124 (5): 737–749.

https://doi.org/10.1182/blood-2013-12-544106

Published: 2014

Includes: Supplemental data

Journal Articles

Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease

Bin Xiao, Yu Wang, Wei Li, Megan Baker, Jian Guo, Kelly Corbet, Ephraim L. Tsalik, Qi-Jing Li, Scott M. Palmer, Christopher W. Woods, Zhiguo Li, Nelson J. Chao, You-Wen He

Blood (2013) 122 (19): 3365–3375.

https://doi.org/10.1182/blood-2013-06-510586

Published: 2013

Includes: Supplemental data

Journal Articles

RNAi Screening Identifies A Novel Role for A-Kinase Anchoring Protein 12 (AKAP12) in B Cell Development and Function

Mutlu Kartal-Kaess, Luisa Cimmino, Simona Infantino, Mehmet Yabas, Jian-Guo Zhang, Laura Tuohey, Irwin H. Gelman, John D. Scott, Stephen L. Nutt, Anselm Enders, David Tarlinton, Ross A Dickins

Blood (2012) 120 (21): 855.

https://doi.org/10.1182/blood.V120.21.855.855

Published: 2012

Journal Articles

Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease

Pichika Chantrathammachart, Nigel Mackman, Erica Sparkenbaugh, Jian-Guo Wang, Leslie V. Parise, Daniel Kirchhofer, Nigel S. Key, Rafal Pawlinski

Blood (2012) 120 (3): 636–646.

https://doi.org/10.1182/blood-2012-04-424143

Published: 2012

Journal Articles

Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer

Jian-Guo Wang, Julia E. Geddings, Maria M. Aleman, Jessica C. Cardenas, Pichika Chantrathammachart, Julie C. Williams, Daniel Kirchhofer, Vladimir Y. Bogdanov, Ronald R. Bach, Janusz Rak, Frank C. Church, Alisa S. Wolberg, Rafal Pawlinski, Nigel S. Key, Jen Jen Yeh, Nigel Mackman

Blood (2012) 119 (23): 5543–5552.

https://doi.org/10.1182/blood-2012-01-402156

Published: 2012

Journal Articles

Monocytic microparticles activate endothelial cells in an IL-1β–dependent manner

Jian-Guo Wang, Julie C. Williams, Beckley K. Davis, Ken Jacobson, Claire M. Doerschuk, Jenny P.-Y. Ting, Nigel Mackman

Blood (2011) 118 (8): 2366–2374.

https://doi.org/10.1182/blood-2011-01-330878

Published: 2011

Journal Articles

Hematopoietic and nonhematopoietic cell tissue factor activates the coagulation cascade in endotoxemic mice

Rafal Pawlinski, Jian-Guo Wang, A. Phillip Owens, III, Julie Williams, Silvio Antoniak, Michael Tencati, Thomas Luther, Jesse W. Rowley, Elizabeth N. Low, Andrew S. Weyrich, Nigel Mackman

Blood (2010) 116 (5): 806–814.

https://doi.org/10.1182/blood-2009-12-259267

Published: 2010

Includes: Supplemental data

Journal Articles

Repulsive axon guidance molecule Slit3 is a novel angiogenic factor

Bing Zhang, Ursula M. Dietrich, Jian-Guo Geng, Roy Bicknell, Jeffrey D. Esko, Lianchun Wang

Blood (2009) 114 (19): 4300–4309.

https://doi.org/10.1182/blood-2008-12-193326

Published: 2009

Includes: Supplemental data

Journal Articles

HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells

Carmen Urbich, Lothar Rössig, David Kaluza, Michael Potente, Jes-Niels Boeckel, Andrea Knau, Florian Diehl, Jian-Guo Geng, Wolf-Karsten Hofmann, Andreas M. Zeiher, Stefanie Dimmeler

Blood (2009) 113 (22): 5669–5679.

https://doi.org/10.1182/blood-2009-01-196485

Published: 2009

Includes: Supplemental data

Journal Articles

T-cell receptor– and CD28-induced Vav1 activity is required for the accumulation of primed T cells into antigenic tissue

Rachel David, Liang Ma, Aleksandar Ivetic, Aya Takesono, Anne J. Ridley, Jian-Guo Chai, Victor L. Tybulewicz, Federica M. Marelli-Berg

Blood (2009) 113 (16): 3696–3705.

https://doi.org/10.1182/blood-2008-09-176511

Published: 2009

Includes: Multimedia, Supplemental data

Journal Articles

The Major Phagocyte Peroxidase-Derived Oxidant, HOSCN (Hypothiocyanous Acid), Induces Proinflammatory and Cytoprotective Gene Expression in Endothelium: A Mechanism for Microlocalized Regulation of Inflammation.

Shawn A. Mahmud, BA, Jian-Guo Wang, Ph.D., Peng Wei, M.S., Molly S. Thomas, Ph.D., John D. Belcher, Ph.D., Gregory M. Vercellotti, M.D., Arne Slungaard, M.D.

Blood (2007) 110 (11): 3295.

https://doi.org/10.1182/blood.V110.11.3295.3295

Published: 2007

Journal Articles

Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia

Benjamin T. Kile, Athanasia D. Panopoulos, Roslynn A. Stirzaker, Douglas F. Hacking, Lubna H. Tahtamouni, Tracy A. Willson, Lisa A. Mielke, Katya J. Henley, Jian-Guo Zhang, Ian P. Wicks, William S. Stevenson, Paquita Nurden, Stephanie S. Watowich, Monica J. Justice

Blood (2007) 110 (7): 2371–2380.

https://doi.org/10.1182/blood-2006-10-055087

Published: 2007

Includes: Supplemental data

Journal Articles

Regulation of Tissue Factor by NF-kB Transcription Factor p50 Is Essential for the Pathogeneses of Deep Vein Thrombosis and Arterial Restenosis.

Jian-Guo Geng, MD, PhD, Jian-Guo Wang, Ph.D., Nigel Mackman, Ph.D., Arne Slungaard, M.D., Yuqing Huo, M.D., Ph.D., Nigel S. Key, M.D.

Blood (2006) 108 (11): 1458.

https://doi.org/10.1182/blood.V108.11.1458.1458

Published: 2006

Journal Articles

The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: a potential mechanism for thrombosis in eosinophilic inflammatory states

Jian-Guo Wang, Shawn A. Mahmud, Jacob A. Thompson, Jian-Guo Geng, Nigel S. Key, Arne Slungaard

Blood (2006) 107 (2): 558–565.

https://doi.org/10.1182/blood-2005-05-2152

Published: 2006

Journal Articles

Lentiviral shRNA silencing of murine bone marrow cell CCR2 leads to persistent knockdown of CCR2 function in vivo

Ilze Bot, Jian Guo, Miranda Van Eck, Peter J. Van Santbrink, Pieter H. E. Groot, Reeni B. Hildebrand, Jurgen Seppen, Theo J. C. Van Berkel, Erik A. L. Biessen

Blood (2005) 106 (4): 1147–1153.

https://doi.org/10.1182/blood-2004-12-4839

Published: 2005

Journal Articles

P-Selectin Activates Leukocyte Integrin alphaMbeta2 by Recruiting Phosphatidylinositol-3 Kinase to P-Selectin Glycoprotein Ligand-1 Cytoplasmic Domain through Adaptor Protein Naf1.

Jian-Guo Geng, MD, Ph.D, Hai-Bo Wang, B.S., Ming Chen, Ph.D., Tao Xu, B.S., Lei Zhang, B.S., Xueliang Zhu, Ph.D., Edward F. Plow, Ph.D.

Blood (2004) 104 (11): 652.

https://doi.org/10.1182/blood.V104.11.652.652

Published: 2004

Journal Articles

P-selectin binding to P-selectin glycoprotein ligand-1 induces an intermediate state of αMβ2 activation and acts cooperatively with extracellular stimuli to support maximal adhesion of human neutrophils

Yan-Qing Ma, Edward F. Plow, Jian-Guo Geng

Blood (2004) 104 (8): 2549–2556.

https://doi.org/10.1182/blood-2004-03-1108

Published: 2004

Journal Articles

Transplantation tolerance induced by intranasal administration of HY peptides

Jian-Guo Chai, Edward James, Hamlata Dewchand, Elizabeth Simpson, Diane Scott

Blood (2004) 103 (10): 3951–3959.

https://doi.org/10.1182/blood-2003-11-3763

Published: 2004

NARROW

In Vitro andpre-Clinical In Vivo evidence Support MDMX/MDM2 As Common Vulnerabilities across TP53 -Wild-Type T-Cell Lymphomas That Are Targetable with the α-Helical p53 Stapled Peptide Alrn-6924

A Two-Site Interaction Underpins TRIM25 Activation of the RIG-I Anti-Viral Response

The polycomb repressive complex 2 governs life and death of peripheral T cells

Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease

RNAi Screening Identifies A Novel Role for A-Kinase Anchoring Protein 12 (AKAP12) in B Cell Development and Function

Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease

Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer

Monocytic microparticles activate endothelial cells in an IL-1β–dependent manner

Hematopoietic and nonhematopoietic cell tissue factor activates the coagulation cascade in endotoxemic mice

Repulsive axon guidance molecule Slit3 is a novel angiogenic factor

HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells

T-cell receptor– and CD28-induced Vav1 activity is required for the accumulation of primed T cells into antigenic tissue

The Major Phagocyte Peroxidase-Derived Oxidant, HOSCN (Hypothiocyanous Acid), Induces Proinflammatory and Cytoprotective Gene Expression in Endothelium: A Mechanism for Microlocalized Regulation of Inflammation.

Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia

Regulation of Tissue Factor by NF-kB Transcription Factor p50 Is Essential for the Pathogeneses of Deep Vein Thrombosis and Arterial Restenosis.

The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: a potential mechanism for thrombosis in eosinophilic inflammatory states

Lentiviral shRNA silencing of murine bone marrow cell CCR2 leads to persistent knockdown of CCR2 function in vivo

P-Selectin Activates Leukocyte Integrin alphaMbeta2 by Recruiting Phosphatidylinositol-3 Kinase to P-Selectin Glycoprotein Ligand-1 Cytoplasmic Domain through Adaptor Protein Naf1.

P-selectin binding to P-selectin glycoprotein ligand-1 induces an intermediate state of αMβ2 activation and acts cooperatively with extracellular stimuli to support maximal adhesion of human neutrophils

Transplantation tolerance induced by intranasal administration of HY peptides

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American Society of Hematology

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American Society of Hematology

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